Pycnogenol in cigarette filters scavenges free radicals and reduces mutagenicity and toxicity of tobacco smoke in vivo.

abstract：:Peracetic acid (PAA) is a corrosive chemical with a pungent odor, which is extensively used in occupational settings and causes various health hazards in exposed workers. Currently, there is no US government agency recommended method that could be applied universally for the sampling and analysis of PAA. Legacy method...

journal_title：Toxicology and industrial health

authors： Nordling J,Kinsky OR,Osorio M,Pechacek N

更新日期：2017-12-01 00:00:00

abstract：:The current study explores the effects of the inhalation of lead (Pb), Cd and its mixture (Pb-Cd) in a mice model, analysing metal concentrations in the lung, and the morphological modifications in the bronchiolar epithelium identified by scanning electron microscopy after eight weeks of inhalation. Our results indica...

journal_title：Toxicology and industrial health

authors： Fortoul TI,Avila-Costa MR,Espejel-Maya G,Mussali-Galante P,Avila-Casado Mdel C,Hernández-Serrato MI,Saldivar-Osorio L

更新日期：2004-06-01 00:00:00

abstract：:Exposure estimates produced using predictive exposure assessment methods are associated with a number of uncertainties that relate to the inherent variability of the values for a given input parameter (e.g., body weight, ingestion rate, inhalation rate) and to unknowns concerning the representativeness of the assumpti...

journal_title：Toxicology and industrial health

authors： Whitmyre GK,Driver JH,Ginevan ME,Tardiff RG,Baker SR

更新日期：1992-09-01 00:00:00

abstract：:As one of the main components of risk assessment, exposure assessment plays a key role in evaluating risk. Many different scenarios can be developed to estimate the risk from exposure to chemicals such as persistent organic pollutants (POPs). The US Food and Drug Administration (FDA)'s Center for Food Safety and Appli...

journal_title：Toxicology and industrial health

authors： Jensen E,Egan S,Canady R,Bolger P

更新日期：2001-06-01 00:00:00

abstract：:The US EPA and the California Air Resources Board studied the exposures of 51 residents of Los Angeles, CA to 25 volatile organic chemicals in air and drinking water in February and July of 1987. Participants carried a personal air monitor consisting of a Tenax cartridge and a small sampling pump for two consecutive 1...

journal_title：Toxicology and industrial health

authors： Wallace LA

更新日期：1991-09-01 00:00:00

abstract：:Atrazine is a commonly used herbicide that has previously been implicated as an endocrine-disrupting compound. Previous studies have shown that estrogenic endocrine-disrupting compounds affect the development of the heart, cartilage, and bone in zebrafish ( Danio rerio). To determine whether atrazine has effects simil...

journal_title：Toxicology and industrial health

authors： Walker BS,Kramer AG,Lassiter CS

更新日期：2018-05-01 00:00:00

abstract：:The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...

journal_title：Toxicology and industrial health

authors： Moselhy SS,Kumosani TA,Al-Malki AL,Naif AA

更新日期：2015-04-01 00:00:00

abstract：:Groups of five male and five female rats were fed diets containing from 0% to 2.5% di(2-ethylhexyl)terephthalate (DEHT) or 1.2% di(2-ethylhexyl)phthalate (DEHP) for 21 days. Feed consumption and body weight gains were collected and, at study termination, animals were examined for alterations in body weight, difference...

journal_title：Toxicology and industrial health

authors： Topping DC,Ford GP,Evans JG,Lake BG,O'Donoghue JL,Lockhart HB Jr

更新日期：1987-06-01 00:00:00

abstract：:Nanomaterials are widely used nowadays in a range of technological and biomedical fields. Graphene as a nanomaterial used in the health-care sector and in workplaces has raised some concerns about its toxicity. This study aimed to evaluate the cytotoxicity of graphene nanoparticles (GNPs) on the A549 epithelial cells ...

journal_title：Toxicology and industrial health

authors： Nasirzadeh N,Azari MR,Rasoulzadeh Y,Mohammadian Y

更新日期：2019-01-01 00:00:00

abstract：:'Toxicant-induced loss of tolerance' (or TILT) describes a two-step disease process in which (1) certain chemical exposures, e.g., indoor air contaminants, chemical spills, or pesticide applications, cause certain susceptible persons to lose their prior natural tolerance for common chemicals, foods, and drugs (initiat...

journal_title：Toxicology and industrial health

authors： Miller CS

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：STUDY OBJECTIVES:Asbestos bodies (ABs) form as asbestos fibers become coated by a cellular iron- and protein-rich matrix. ABs have been reported in lymph nodes and a few extrapulmonary sites, but no data exist as to their formation outside of the lung. It is not clear whether the AB found in these extrapulmonary areas ...

journal_title：Toxicology and industrial health

authors： Williams MG,Dodson RF,Dickson EW,Fraire AE

更新日期：2001-02-01 00:00:00

abstract：:Significant numbers of chemicals have been shown to be carcinogenic in mouse liver although they do not exhibit carcinogenic activity in other organs or tissues of mice or rats. This review focuses on the reasons for the unique susceptibility of the mouse liver to these carcinogens and the extent to which the carcinog...

journal_title：Toxicology and industrial health

authors： Pereira MA

更新日期：1985-12-01 00:00:00

abstract：:Aflatoxin B1 (AFB1) is a toxic compound commonly found as a contaminant in human food. It is carcinogenic due its potential in inducing the oxidative stress and distortion of the most antioxidant enzymes. Since black tea possesses strong antioxidant activity, it protects cells and tissues against oxidative stress. Cur...

journal_title：Toxicology and industrial health

authors： Alm-Eldeen AA,Mona MH,Shati AA,El-Mekkawy HI

更新日期：2015-12-01 00:00:00

abstract：:Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liver failure, but therapeutic doses are believed to be safe. The purpose of this study is to investigate the effects of administration of subtoxic doses of APAP on liver and blood levels of insulin-like growth factor-1 (IGF-...

journal_title：Toxicology and industrial health

authors： Ozdemir D,Aksu I,Baykara B,Ates M,Sisman AR,Kiray M,Buyuk A,Uysal N

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to evaluate the global scientific output of neurotoxicity of nanoparticles (NPs) and explore their hot spots and research trends. Articles about the neurotoxicity of NPs between 2008 and 2017 were taken from the Web of Science Core Collection database. The VOSviewer was used to analyze annual...

journal_title：Toxicology and industrial health

authors： Su B,Guan Q,Yu S

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Polycyclic aromatic hydrocarbons (PAHs) are potent environmental pollutants. Benzo[α]pyrene (B[α]P) is the major compound of PAHs that acts by activating aryl hydrocarbon receptor (AhR) in cells. B[α]P is a known carcinogen and an immunotoxicant; however, its role with regard to nuclear factor of activated T ...

journal_title：Toxicology and industrial health

authors： Parsa M,Ostad SN,Moogahi SM,Bayat M,Ghahremani MH

更新日期：2016-07-01 00:00:00

abstract：:A meta-analysis of epidemiologic studies for textile industry workers was undertaken in an attempt to evaluate whether the cancer risk varies within the textile industry in relation to the job held or the textile fiber used. We combined studies published up until 1990, when an ad hoc IARC Monograph was issued, and tho...

journal_title：Toxicology and industrial health

authors： Mastrangelo G,Fedeli U,Fadda E,Milan G,Lange JH

更新日期：2002-05-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:The mechanism by which granulocyte colony-stimulating factor (G-CSF) could lead to the protection from liver injury is not well known. Therefore, the resolution of this role needs further basic and clinical experimental investigation. Acute liver injury was induced in rats by single intraperitoneal injection of a 0.50...

journal_title：Toxicology and industrial health

authors： Qujeq D,Abassi R,Faeizi F,Parsian H,Faraji AS,Taheri H,Tatar M,Elmi MM,Halalkhor S

更新日期：2013-07-01 00:00:00

abstract：:This study was realized to investigate the possible beneficial effect of thymoquinone (TQ), the major active component of volatile oil of Nigella sativa seeds, against lead (Pb)-induced inhibition of rat testicular functions. Adult rats were randomized into four groups: a control group receiving no treatment; a Pb gro...

journal_title：Toxicology and industrial health

authors： Mabrouk A,Ben Cheikh H

更新日期：2016-06-01 00:00:00

abstract：:In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...

journal_title：Toxicology and industrial health

authors： Mussali-Galante P,Avila-Costa MR,Piñón-Zarate G,Martínez-Levy G,Rodríguez-Lara V,Rojas-Lemus M,Avila-Casado MC,Fortoul TI

更新日期：2005-09-01 00:00:00

abstract：:Two prospective, longitudinal studies-one in North Carolina and one in Michigan-have examined effects of prenatal polychlorinated biphenyl (PCB) exposure on behavioral and cognitive development in infants and children. The Michigan cohort was selected to overrepresent the offspring of women who had eaten relatively la...

journal_title：Toxicology and industrial health

authors： Jacobson JL,Jacobson SW

更新日期：1996-05-01 00:00:00

abstract：:In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...

journal_title：Toxicology and industrial health

authors： Ozkurkcugil C,Yilmaz MY,Ozkan L,Kokturk S,Isken T

更新日期：2011-05-01 00:00:00

abstract：:The aim of this study was to investigate the different testicular toxicity and the role of apoptosis in the possible mechanism induced by the two isomers of bromopropanes (BPs) in the same dosage. Following the 14-day treatment with a single dose of 1-BP and 2-BP (1 g/kg), male rats were killed and a series of experim...

journal_title：Toxicology and industrial health

authors： Xin QQ,Yong Huang,Jie Li,Zhang WJ,Tao Yu,Hua Wang,Cheng Zhang,Ye DQ,Fen Huang

更新日期：2010-09-01 00:00:00

abstract：:Orange B, a pyrazolone dye used to color frankfurter and sausage casings, was given in distilled drinking water to pregnant Osborne-Mendel rats throughout gestation. Assessed on the basis of fluid consumption, the dose levels of 0, 0.05, 0.1, 0.2, and 0.4% corresponded to daily Orange B consumption of 0, 67.5, 129.6, ...

journal_title：Toxicology and industrial health

authors： Collins TF,Black TN,Ruggles DI

更新日期：1995-07-01 00:00:00

abstract：:Flight personnel are exposed to cosmic ionizing radiation, chemicals (fuel, jet engine exhausts, cabin air pollutants), electromagnetic fields from cockpit instruments, and disrupted sleep patterns. Only recently has cancer risk among these workers been investigated. With the aim of increasing the precision of risk es...

journal_title：Toxicology and industrial health

authors： Buja A,Lange JH,Perissinotto E,Rausa G,Grigoletto F,Canova C,Mastrangelo G

更新日期：2005-11-01 00:00:00

abstract：:Environmental Impact Assessment is essentially a process comprising four elements: identification, prediction, evaluation, and monitoring. Properly conducted EIA studies can identify linkages between injurious events and/or activities and their damaging consequences. This aids in making the risk management decision. T...

journal_title：Toxicology and industrial health

authors： Ratanachai C

更新日期：1991-09-01 00:00:00

abstract：:Forty-nine female workers in the shoemaking industry, exposed to a solvent mixture containing benzene and twenty-seven non-exposed controls, were investigated. Concentrations of benzene and toluene in the working atmosphere, as well as benzene and toluene in blood and phenols in pre- and post-shift urine as parameters...

journal_title：Toxicology and industrial health

authors： Bogadi-Sare A,Turk R,Karacić V,Zavalić M,Trutin-Ostović K

更新日期：1997-07-01 00:00:00

abstract：:The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. Exposure of mice to JP-8 for 1 h/day resulted in immediate secretion ...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,Titone D,He X,Hyde J,Witten M

更新日期：2007-11-01 00:00:00