Detection of macrocyclic trichothecene mycotoxin in a caprine (goat) tracheal instillation model.

abstract：:Hepato-toxicity of cadmium in alloxan induced diabetic rats has been studied by estimating a few enzymes viz serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and gamma-glutamyltranspeptidase. Present results suggest that cadmium manifests different effects in normal and diabe...

journal_title：Toxicology and industrial health

authors： Rana SV,Rastogi N

更新日期：1998-05-01 00:00:00

abstract：:Exposure estimates produced using predictive exposure assessment methods are associated with a number of uncertainties that relate to the inherent variability of the values for a given input parameter (e.g., body weight, ingestion rate, inhalation rate) and to unknowns concerning the representativeness of the assumpti...

journal_title：Toxicology and industrial health

authors： Whitmyre GK,Driver JH,Ginevan ME,Tardiff RG,Baker SR

更新日期：1992-09-01 00:00:00

abstract：:Microcystins (MCs) are the most potent toxins that can be produced by cyanobacteria in drinking water supplies. This study investigated the abundance of toxin-producing algae in 11 drinking water treatment plants (DWTPs). A total of 26 different algal taxa were identified in treated water, from which 12% were blue gre...

journal_title：Toxicology and industrial health

authors： Ibrahim WM,Salim EH,Azab YA,Ismail AH

更新日期：2016-10-01 00:00:00

abstract：:This study focuses on investigating the possible protective effect of sodium selenite (Na2SeO3) and/or vitamin E against mercuric chloride (HgCl2)-induced hepatotoxicity in rat. Male rats were given HgCl2 (1 mg/kg body weight (bw)) and HgCl2 plus Na2SeO3 (0.25 mg/kg bw) and/or vitamin E (100 mg/kg bw) daily via gavage...

journal_title：Toxicology and industrial health

authors： Uzunhisarcikli M,Aslanturk A,Kalender S,Apaydin FG,Bas H

更新日期：2016-09-01 00:00:00

abstract：:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

journal_title：Toxicology and industrial health

authors： Lange JH,Chang YF,LaPorte RE,Mastrangelo G

更新日期：2003-07-01 00:00:00

abstract：:The US EPA and the California Air Resources Board studied the exposures of 51 residents of Los Angeles, CA to 25 volatile organic chemicals in air and drinking water in February and July of 1987. Participants carried a personal air monitor consisting of a Tenax cartridge and a small sampling pump for two consecutive 1...

journal_title：Toxicology and industrial health

authors： Wallace LA

更新日期：1991-09-01 00:00:00

abstract：:Lead exposure can damage cells directly by effecting DNA or indirectly by modifying proteins and enzymes. In Bangladesh, many working children are exposed to a very high level of lead during their early life due to their involvement with lead-oriented professions. This imposes a severe threat to the growth and develop...

journal_title：Toxicology and industrial health

authors： Arif M,Islam MT,Shekhar HU

更新日期：2018-04-01 00:00:00

abstract：:In the present study, the single and combined neurotoxic effects of benzo[a]pyrene ([BaP] 0.0, 0.5, and 5.0 mg/kg body weight; intragastric administration) and lead acetate (0.0, 5.4, and 54.0 mg/L; by drinking water) were examined on KunMing mice. In the Morris water maze, results showed that BaP and lead induced syn...

journal_title：Toxicology and industrial health

authors： Youbin Q,Chengzhi C,Yan T,Xuejun J,Chongying Q,Bin P,Baijie T

更新日期：2013-06-01 00:00:00

abstract：:Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia...

journal_title：Toxicology and industrial health

authors： Al-Zoughool M,Al-Shehri Z

更新日期：2018-09-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Several classes of environmental contaminants have been claimed or suggested to possess endocrine-disrupting potency, which may result in reproductive problems and developmental disorders. In this paper the focus is on the multiple and interactive mechanisms of interference of persistent polyhalogenated aromatic hydro...

journal_title：Toxicology and industrial health

authors： Brouwer A,Morse DC,Lans MC,Schuur AG,Murk AJ,Klasson-Wehler E,Bergman A,Visser TJ

更新日期：1998-01-01 00:00:00

abstract：:Ferric nitrilotriacetate (Fe-NTA) is a known renal carcinogen and has been shown to adversely induce oxidative stress and tissue toxicity after both acute and chronic exposure. Present studies were designed to study the hepatoprotective and antioxidant potential of butylated hydroxyanisole (BHA), a phenolic antioxidan...

journal_title：Toxicology and industrial health

authors： Ansar S,Iqbal M

更新日期：2015-11-01 00:00:00

abstract：:The aim of this study was to evaluate the global scientific output of neurotoxicity of nanoparticles (NPs) and explore their hot spots and research trends. Articles about the neurotoxicity of NPs between 2008 and 2017 were taken from the Web of Science Core Collection database. The VOSviewer was used to analyze annual...

journal_title：Toxicology and industrial health

authors： Su B,Guan Q,Yu S

更新日期：2018-12-01 00:00:00

abstract：:The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...

journal_title：Toxicology and industrial health

authors： Mumtaz MM,Durkin PR

更新日期：1992-11-01 00:00:00

abstract：:Endothelial adhesion plays an important role in the process of atherosclerosis, which is regulated by endothelial adhesion molecules and chemoattractant molecules. In some areas of China, citreoviridin (CIT) is considered a risk factor for the development of atherosclerosis. Here, we investigated the role of CIT in ad...

journal_title：Toxicology and industrial health

authors： Hou H,Zhou R,Jia Q,Li Q,Kang L,Jiao P,Li D,Jiang B

更新日期：2015-03-01 00:00:00

abstract：:1,2-Dichloropropane (1,2-DCP), a solvent, which is the main component of the cleaner used in the offset printing companies in Japan, is suspected to be the causative agent of bile duct cancer, which has been recently reported at high incidence in those offset printing workplaces. While there are some reports about the...

journal_title：Toxicology and industrial health

authors： Yanagiba Y,Suzuki T,Suda M,Hojo R,Gonzalez FJ,Nakajima T,Wang RS

更新日期：2016-09-01 00:00:00

abstract：:The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6...

journal_title：Toxicology and industrial health

authors： Vena JE,Buck GM,Kostyniak P,Mendola P,Fitzgerald E,Sever L,Freudenheim J,Greizerstein H,Zielezny M,McReynolds J,Olson J

更新日期：1996-05-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:The morphological changes of ricin-induced apoptosis in a human cervical cancer cell line were studied. To shed light on the mechanism of action of ricin toxin (RT) at the cellular level, we examined cell growth, apoptosis, changes of mitochondrial membrane potential (MMP) and cytochrome C translocation in HeLa cells ...

journal_title：Toxicology and industrial health

authors： Liao P,Liu W,Li H,Gao H,Wang H,Li N,Xu N,Li J,Wan J,Liu L,Sun Y

更新日期：2012-06-01 00:00:00

abstract：:Cytochrome P450 2E1 (CYP2E1) can be induced by diabetes mellitus, nonalcoholic liver disease, and obesity. This study assessed the protective effects of three sulfur compounds, namely phenethyl isothiocyanate (PEITC), dimethyl trisulfide (DMTS), and sodium thiosulfate (STS), on acrylonitrile (ACN)-induced acute toxici...

journal_title：Toxicology and industrial health

authors： Li F,Lu R,Zhao T,Zhang X,Wang S,Xing G

更新日期：2019-05-01 00:00:00

abstract：:The negative health effects caused by lead (Pb) exposure are widely recognized; however, the molecular mechanisms remain unknown. The aim of this study was to assess the effect of occupational Pb exposure on telomere length and to investigate the potential mechanisms leading to telomere shortening. A cohort of 334 mal...

journal_title：Toxicology and industrial health

authors： Pawlas N,Płachetka A,Kozłowska A,Mikołajczyk A,Kasperczyk A,Dobrakowski M,Kasperczyk S

更新日期：2016-12-01 00:00:00

abstract：:Kinetic interactions among chemicals present in a mixture can influence the relationship between administered and delivered or effective dose; these interactions are distinct from dynamic interactions such as, for example, competition between two chemicals for receptor binding sites. The relationship between administe...

journal_title：Toxicology and industrial health

authors： O'Flaherty EJ

更新日期：1989-10-01 00:00:00

abstract：:This investigation gives detailed analysis of peripheral marker enzymes as well as neurobehavioral tests following chronic aluminium (Al) exposure (10 mg/kg b.w. for 12 weeks intragastrically). We observed a significant decrease in the levels of serum cholinesterase after toxicity. The enzymatic activity of cytochrome...

journal_title：Toxicology and industrial health

authors： Kaur A,Gill KD

更新日期：2006-02-01 00:00:00

abstract：:An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine (DFO), in removing cadmium from biological system. The potential efficiency of those chelators were investigated after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight dai...

journal_title：Toxicology and industrial health

authors： Fatemi SJ,Saljooghi AS,Balooch FD,Iranmanesh M,Golbafan MR

更新日期：2012-02-01 00:00:00

abstract：:The gem-polishing industry in Jaipur, India employs a substantial proportion of children. The process of polishing may result in exposure to chromium in working children. Thus, this study aims to find out the levels of chromium in these working children and the associated factors. Blood samples were analysed for chrom...

journal_title：Toxicology and industrial health

authors： Tiwari RR,Saha A,Sathwara NG,Parikh JR

更新日期：2012-03-01 00:00:00

abstract：:The anti-genotoxic potential of hydrated sodium calcium aluminosilicate (HSCAS) was investigated using sister chromatid exchanges (SCEs) induced by aflatoxin B1 (AFB1) as genotoxic endpoint in human lymphocytes. Whole blood samples from two healthy male donors were used for this experiment and the effects of different...

journal_title：Toxicology and industrial health

authors： Türkez H,Sişman T

更新日期：2007-03-01 00:00:00

abstract：:2,4-dinitroanisole (DNAN) is a warhead explosive currently under investigation as a replacement for TNT in melt-cast insensitive munitions. In animal studies, DNAN is a mild ocular and skin irritant with a significant potential for dermal absorption.  It is not a dermal sensitizer.  Acute and subacute rat inhalation s...

journal_title：Toxicology and industrial health

authors：

更新日期：2018-01-01 00:00:00

abstract：:Paraquat has been shown to be a highly toxic compound for humans and animals, and many cases of acute poisoning and death have been reported over the past few decades. The present study was undertaken to evaluate comprehensively herbicides (Paraquat) and some plant extracts to biochemical aspects of Lymnaea natalensis...

journal_title：Toxicology and industrial health

authors： Bakry FA,Eleiwa ME,Taha SA,Ismil SM

更新日期：2016-01-01 00:00:00

abstract：:In the present study, we attempted to elucidate the induction of autophagy in rat hepatocytes by a low concentration of mercury. Hepatocytes treated with different doses of mercuric chloride (HgCl2; 1, 2.5, 5 and 10 µM) and at different time intervals (0 min, 30 min, 1 h, 2 h and 4 h) show autophagic cell death only a...

journal_title：Toxicology and industrial health

authors： Chatterjee S,Ray A,Mukherjee S,Agarwal S,Kundu R,Bhattacharya S

更新日期：2014-08-01 00:00:00

abstract：:Significant numbers of chemicals have been shown to be carcinogenic in mouse liver although they do not exhibit carcinogenic activity in other organs or tissues of mice or rats. This review focuses on the reasons for the unique susceptibility of the mouse liver to these carcinogens and the extent to which the carcinog...

journal_title：Toxicology and industrial health

authors： Pereira MA

更新日期：1985-12-01 00:00:00