Effects of cadmium on liver function in diabetic rats.

Abstract:

:Hepato-toxicity of cadmium in alloxan induced diabetic rats has been studied by estimating a few enzymes viz serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and gamma-glutamyltranspeptidase. Present results suggest that cadmium manifests different effects in normal and diabetic rats. Insulin therapy helps in restoring the liver function. It is suggested that an isozyme of cytochrome P450 that appears in diabetic rats might be responsible for altered toxicity of cadmium.

journal_name

Toxicol Ind Health

authors

Rana SV,Rastogi N

doi

10.1177/074823379801400306

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

473-7

issue

3

eissn

0748-2337

issn

1477-0393

journal_volume

14

pub_type

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