Inhalation toxicity study of methanol, toluene, and methanol/toluene mixtures in rats: effects of 28-day exposure.

abstract：:The morphological changes of ricin-induced apoptosis in a human cervical cancer cell line were studied. To shed light on the mechanism of action of ricin toxin (RT) at the cellular level, we examined cell growth, apoptosis, changes of mitochondrial membrane potential (MMP) and cytochrome C translocation in HeLa cells ...

journal_title：Toxicology and industrial health

authors： Liao P,Liu W,Li H,Gao H,Wang H,Li N,Xu N,Li J,Wan J,Liu L,Sun Y

更新日期：2012-06-01 00:00:00

abstract：:A more complicated pathology was observed in female pigs infected with Mycoplasma hyopneumoniae, when the same were exposed to 20 ppm dietary levels of fumonisin B1 (FB1) starting 14 days before infection for a period of 42 days as was assessed by gross pathology and pathomorphological examinations or computed tomogra...

journal_title：Toxicology and industrial health

authors： Pósa R,Stoev S,Kovács M,Donkó T,Repa I,Magyar T

更新日期：2016-06-01 00:00:00

abstract：:Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 mont...

journal_title：Toxicology and industrial health

authors： Hopper DL,Kernan WJ,Lloyd WE

更新日期：1986-07-01 00:00:00

abstract：STUDY OBJECTIVES:Asbestos bodies (ABs) form as asbestos fibers become coated by a cellular iron- and protein-rich matrix. ABs have been reported in lymph nodes and a few extrapulmonary sites, but no data exist as to their formation outside of the lung. It is not clear whether the AB found in these extrapulmonary areas ...

journal_title：Toxicology and industrial health

authors： Williams MG,Dodson RF,Dickson EW,Fraire AE

更新日期：2001-02-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of resveratrol on kidney tissue of rats exposed to cigarette smoke. Forty adult male Wistar Albino rats were divided into four groups. Animals in group 1 was the control group. For 6 weeks, group 2 was exposed to cigarette smoke; group 3 received daily intraperitoneal i...

journal_title：Toxicology and industrial health

authors： Kuruş M,Ugras M,Esrefoglu M

更新日期：2009-09-01 00:00:00

abstract：:Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...

journal_title：Toxicology and industrial health

authors： Holder JW

更新日期：2008-11-01 00:00:00

abstract：:The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...

journal_title：Toxicology and industrial health

authors： Moselhy SS,Kumosani TA,Al-Malki AL,Naif AA

更新日期：2015-04-01 00:00:00

abstract：:Widespread use of mobile phones which are a major source of electromagnetic fields might affect living organisms. However, there has been no investigation concerning prenatal exposure to electromagnetic fields or their roles in the development of the pyramidal cells of the cornu ammonis in postnatal life. Two groups o...

journal_title：Toxicology and industrial health

authors： Bas O,Odaci E,Mollaoglu H,Ucok K,Kaplan S

更新日期：2009-07-01 00:00:00

abstract：:Hepatocarcinogens are agents that increase the incidence of liver cancer in exposed animals or humans. It is now established that carcinogenic exposures have a widespread impact on the transcriptome, inducing both adaptive and adverse changes in the activities of genes and pathways. Chemical hepatocarcinogens have als...

journal_title：Toxicology and industrial health

authors： Nicolaidou V,Koufaris C

更新日期：2020-05-01 00:00:00

abstract：:Chloropentafluorobenzene (CPFB) has been identified as a candidate simulant for nonpersistent chemical warfare agents. Acute toxicity studies have shown that CPFB has limited adverse effects on laboratory animals. A 21-day inhalation study of rats and mice to 2.5, 0.8, and 0.25 mg CPFB/liter resulted in reduced weight...

journal_title：Toxicology and industrial health

authors： Kinkead ER,Bunger SK,Kimmel EC,Flemming CD,Wall HG,Grabau JH

更新日期：1991-07-01 00:00:00

abstract：:Hepato-toxicity of cadmium in alloxan induced diabetic rats has been studied by estimating a few enzymes viz serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and gamma-glutamyltranspeptidase. Present results suggest that cadmium manifests different effects in normal and diabe...

journal_title：Toxicology and industrial health

authors： Rana SV,Rastogi N

更新日期：1998-05-01 00:00:00

abstract：:The present study investigates the toxic effects of acrylamide (ACR) administered to rats at two doses on (i) oxidative stress and disruption of pro-oxidant/antioxidant balance in hepatic cells and (ii) its correlation with metallothioneins (MTs) genes expression, DNA damage and histomorphological changes. Treated rat...

journal_title：Toxicology and industrial health

authors： Ghorbel I,Elwej A,Chaabene M,Boudawara O,Marrakchi R,Jamoussi K,Boudawara TS,Zeghal N

更新日期：2017-08-01 00:00:00

abstract：:1,2-Dichloropropane (1,2-DCP), a solvent, which is the main component of the cleaner used in the offset printing companies in Japan, is suspected to be the causative agent of bile duct cancer, which has been recently reported at high incidence in those offset printing workplaces. While there are some reports about the...

journal_title：Toxicology and industrial health

authors： Yanagiba Y,Suzuki T,Suda M,Hojo R,Gonzalez FJ,Nakajima T,Wang RS

更新日期：2016-09-01 00:00:00

abstract：:Within hours after the terrorist attack on the Pentagon on September 11, 2001, an extensive sampling effort was initiated within the building to include surface wipe sampling for select coplanar polychlorinated biphenyls (PCBs), congeners of polychlorinated dibenzo(p)dioxins and dibenzofurans (dioxins/furans) and lead...

journal_title：Toxicology and industrial health

authors： Gaborek BJ,Mullikin JM,Pitrat AT,Cummings L,May LM

更新日期：2001-06-01 00:00:00

abstract：:Aflatoxin B1 (AFB1) is a toxic compound commonly found as a contaminant in human food. It is carcinogenic due its potential in inducing the oxidative stress and distortion of the most antioxidant enzymes. Since black tea possesses strong antioxidant activity, it protects cells and tissues against oxidative stress. Cur...

journal_title：Toxicology and industrial health

authors： Alm-Eldeen AA,Mona MH,Shati AA,El-Mekkawy HI

更新日期：2015-12-01 00:00:00

abstract：:The aim of this study was to evaluate the antiapoptotic and proliferative activity of curcumin (Cur) on the ovarian follicles in mice exposed to whole body ionizing radiation (Rd). The mice were exposed to 8.3 gray whole body Rd, and Cur groups were given as a daily dose of 100 mg/kg of Cur for 10 days (10 days before...

journal_title：Toxicology and industrial health

authors： Aktas C,Kanter M,Kocak Z

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:For several decades, there has been increasing evidence for excess incidence of lung cancer among workers in the rubber industry. The purpose of this study was to assess the risk of lung cancer occurrence among Egyptian workers involved in the rubber industry using two circulating protein biomarkers. METHODS...

journal_title：Toxicology and industrial health

authors： Mourad BH

更新日期：2020-04-01 00:00:00

abstract：:In the present work, 6 honeydew samples of known geographical and botanical origins and 11 honeybee samples were analyzed to detect possible contamination by the thermoelectric power plants in Mugla, Turkey. The contents of trace elements were determined by atomic absorption spectrometry after application of microwave...

journal_title：Toxicology and industrial health

authors： Silici S,Uluozlu OD,Tuzen M,Soylak M

更新日期：2016-03-01 00:00:00

abstract：:The human teratogenic potential of chlordiazepoxide is debated. To study the effects on the fetal development of very large doses of chlordiazepoxide that were used for a suicide attempt during pregnancy, self-poisoned pregnant women were identified from patients in a toxicological inpatient clinic in Budapest, Hungar...

journal_title：Toxicology and industrial health

authors： Gidai J,Acs N,Bánhidy F,Czeizel AE

更新日期：2008-02-01 00:00:00

abstract：:Peracetic acid (PAA) is a corrosive chemical with a pungent odor, which is extensively used in occupational settings and causes various health hazards in exposed workers. Currently, there is no US government agency recommended method that could be applied universally for the sampling and analysis of PAA. Legacy method...

journal_title：Toxicology and industrial health

authors： Nordling J,Kinsky OR,Osorio M,Pechacek N

更新日期：2017-12-01 00:00:00

abstract：:The developmental toxicity of 2,4-Pentanedione (2,4-PD; CAS No. 123-54-6), a widely used industrial chemical, was investigated by vapour exposure, because of its widespread use, and potential for human exposure. Timed-pregnant Fischer 344 rats were exposed on gestational days (gd) 6 to 15 inclusive to analytically mea...

journal_title：Toxicology and industrial health

authors： Tyl RW,Ballantyne B,Pritts IM,Garman RH,Fisher LC,France KA,McNeil DJ

更新日期：1990-05-01 00:00:00

abstract：:Retinyl esters are the storage form of vitamin A in skin, and retinyl palmitate (RP) accounts for the majority of the retinyl esters endogenously formed in skin. RP is also obtained exogenously through the topical application of cosmetic and skin care products that contain RP. There is limited information on the penet...

journal_title：Toxicology and industrial health

authors： Yan J,Wamer WG,Howard PC,Boudreau MD,Fu PP

更新日期：2006-05-01 00:00:00

abstract：:The purpose of this study was to characterize the ultrastructural changes in the muscles of 2- and 6-month-old rats that were injected with 6-mercaptopurine monohydrate (6-MP) at 2 mg base/kg sc daily from 2 to 22 days of age. The earliest, usually subsarcolemmal alterations, were disorganization of fibrils at the Z-b...

journal_title：Toxicology and industrial health

authors： Abraham AA,Veronesi B,Alleva FR,Balazs T

更新日期：1986-09-01 00:00:00

abstract：:The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...

journal_title：Toxicology and industrial health

authors： Ajiboye TO,Komolafe YO,Yakubu MT,Ogunbode SM

更新日期：2015-02-01 00:00:00

abstract：:Continuous occupational exposure to spent engine oil (SEO) poses physiological risks to humans, especially to automobile mechanics. This study investigated the physiological effects of SEO-contaminated soil in a male Wistar rat model. Animals were dermally exposed to soil contaminated with SEO for 120 consecutive days...

journal_title：Toxicology and industrial health

authors： Obiyo GE,Ogunsuyi OM,Akindele O A

更新日期：2020-12-01 00:00:00

abstract：:Cutting fluids can become contaminated with metals (e.g., nickel, Ni) and nitrosamines (e.g., N-nitrosodiethanolamine, NDELA) and there is concern that these classes of contaminants can modulate dermal disposition and ultimately the toxicity of cutting fluid additives, such as irritant biocides (e.g., triazine). Bioci...

journal_title：Toxicology and industrial health

authors： Baynes RE,Brooks JD,Barlow BM,Riviere JE

更新日期：2005-10-01 00:00:00

abstract：:Holothuria polii (Delle Chiaje, 1823) (Holothuriidae) is a sea cucumber inhabiting Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal, antibacterial and antiparasitic effects. The present study aims to elucidate the structure of the bioactive material of H. polii for pharmacologica...

journal_title：Toxicology and industrial health

authors： Omran NE,Khedr AM

更新日期：2015-01-01 00:00:00

abstract：:The effect of copper in form of copper sulphate (CuSO4 x 5 H2O) was studied in the bone marrow cells of rats of Wistar strain in an in vitro culture. Evident differences between tissue cultures of the bone marrow cells were observed between the control and experimental groups. In the experimental group, the CFU-F colo...

journal_title：Toxicology and industrial health

authors： Miszta H

更新日期：1989-12-01 00:00:00

abstract：:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accur...

journal_title：Toxicology and industrial health

authors： Lange JH,Chang YF,LaPorte RE,Mastrangelo G

更新日期：2003-07-01 00:00:00

abstract：:In The Netherlands, risk assessment of air pollutants goes back to 1980. From 1985 onwards the risk assessment of chemicals has crystallized in a systematic multi-media approach taking into account air, water, soil, and food. Criteria Documents support the formulation of environmental quality standards. Until now, 23 ...

journal_title：Toxicology and industrial health

authors： Vermeire T,van der Heijden K

更新日期：1990-10-01 00:00:00