A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae.

abstract：:In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...

journal_title：Toxicology and industrial health

authors： Mussali-Galante P,Avila-Costa MR,Piñón-Zarate G,Martínez-Levy G,Rodríguez-Lara V,Rojas-Lemus M,Avila-Casado MC,Fortoul TI

更新日期：2005-09-01 00:00:00

abstract：:This study was designed to determine if long-term exposure to high doses of methoxychlor (M) would alter pituitary or testicular endocrine functions in either an estrogenic or antiandrogenic manner. Weanling male Long-Evans hooded rats were dosed daily with M (po) at 0, 200, 300, or 400 mg kg-1 day-1 for 10 months. Me...

journal_title：Toxicology and industrial health

authors： Gray LE Jr,Ostby J,Cooper RL,Kelce WR

更新日期：1999-01-01 00:00:00

abstract：:Significant numbers of chemicals have been shown to be carcinogenic in mouse liver although they do not exhibit carcinogenic activity in other organs or tissues of mice or rats. This review focuses on the reasons for the unique susceptibility of the mouse liver to these carcinogens and the extent to which the carcinog...

journal_title：Toxicology and industrial health

authors： Pereira MA

更新日期：1985-12-01 00:00:00

abstract：:Cyclophosphamide (CP) is an alkylating agent that has been considered effective for cancer treatment. Lycopene, the pigment in tomato fruits, has beneficial effect in the treatment of some diseases. The goal of this study is to evaluate the protective effect of lycopene alone or combined with melatonin (Mel) in inhibi...

journal_title：Toxicology and industrial health

authors： Al-Malki AL

更新日期：2014-07-01 00:00:00

abstract：:The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...

journal_title：Toxicology and industrial health

authors： Ajiboye TO,Komolafe YO,Yakubu MT,Ogunbode SM

更新日期：2015-02-01 00:00:00

abstract：:The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

journal_title：Toxicology and industrial health

authors： Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

更新日期：2015-03-01 00:00:00

abstract：:Many episodes of low back pain are disabling, thus making it one of the costly occupational health problem. The proper alignment and lifting operations during drilling process frequently exposed the oil-drilling workers to unusual strain on the spine and thus make them susceptible for developing low back pain. The pre...

journal_title：Toxicology and industrial health

authors： Tiwari RR,Saha A

更新日期：2014-02-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...

journal_title：Toxicology and industrial health

authors： Maina G,Manzari M,Palmas A,Passini V,Filon FL

更新日期：2007-02-01 00:00:00

abstract：:This study demonstrates the detection and dynamics of macrocyclic trichothecene mycotoxin (MTM) tissue loading using a commercially available assay in a goat model. The detection of MTMs has been difficult and complex due to the uncertainty of what tissues to examine and when to sample. Twelve goats (two groups of eac...

journal_title：Toxicology and industrial health

authors： Layton RC,Purdy CW,Jumper CA,Straus DC

更新日期：2009-10-01 00:00:00

abstract：:Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 mont...

journal_title：Toxicology and industrial health

authors： Hopper DL,Kernan WJ,Lloyd WE

更新日期：1986-07-01 00:00:00

abstract：:Hepatocarcinogens are agents that increase the incidence of liver cancer in exposed animals or humans. It is now established that carcinogenic exposures have a widespread impact on the transcriptome, inducing both adaptive and adverse changes in the activities of genes and pathways. Chemical hepatocarcinogens have als...

journal_title：Toxicology and industrial health

authors： Nicolaidou V,Koufaris C

更新日期：2020-05-01 00:00:00

abstract：:Not only is skin cancer by far the most common human cancer but also the incidence of skin cancer has been increasing at an alarming rate in recent decades. Fortunately, most people now realize that sun exposure causes unattractive photoaging and skin cancer, so they do apply sunscreens conscientiously. However, until...

journal_title：Toxicology and industrial health

authors： Burke KE,Wei H

更新日期：2009-05-01 00:00:00

abstract：:The current study explores the effects of the inhalation of lead (Pb), Cd and its mixture (Pb-Cd) in a mice model, analysing metal concentrations in the lung, and the morphological modifications in the bronchiolar epithelium identified by scanning electron microscopy after eight weeks of inhalation. Our results indica...

journal_title：Toxicology and industrial health

authors： Fortoul TI,Avila-Costa MR,Espejel-Maya G,Mussali-Galante P,Avila-Casado Mdel C,Hernández-Serrato MI,Saldivar-Osorio L

更新日期：2004-06-01 00:00:00

abstract：:Phthalates are abundantly produced plasticizers, and dibutyl phthalate (DBP) is the most widely used derivative in various consumer products and medical devices. This study was conducted to further explore the potential testicular toxicity of DBP in adult rats and to elucidate the underlying mechanisms. Adult male alb...

journal_title：Toxicology and industrial health

authors： Aly HA,Hassan MH,El-Beshbishy HA,Alahdal AM,Osman AM

更新日期：2016-08-01 00:00:00

abstract：:People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

journal_title：Toxicology and industrial health

authors： Ghosh M,Biswas D,Mukherjee A

更新日期：2010-08-01 00:00:00

abstract：:Microbiological studies were carried out on microbial contamination and antimicrobial activity of sea cucumber Holothuria polii collected from Mediterranean Sea at Abu-kir shore of Alexandria, Egypt. The obtained results revealed the presence of isolates of five human Gram-negative pathogenic bacteria, representing fi...

journal_title：Toxicology and industrial health

authors： Omran NE,Allam NG

更新日期：2013-11-01 00:00:00

abstract：:Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to both sexes of rats and 0, 44, 88, 1...

journal_title：Toxicology and industrial health

authors： Matthews HB,Dixon D,Herr DW,Tilson H

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：:In this study, the cytotoxic potential of fluoride and endosulfan in combination was investigated in Swiss albino mice bone marrow cells using the chromosomal aberration (CA) and micronucleus (MN) test systems. Fluoride (25.1 mg kg-1 body weight [bw] in water) and endosulfan (1.8 mg kg-1 bw by oral intubation) were ad...

journal_title：Toxicology and industrial health

authors： Sharma A,John P,Bhatnagar P

更新日期：2020-12-16 00:00:00

abstract：:The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group,...

journal_title：Toxicology and industrial health

authors： Koltover VK

更新日期：2009-05-01 00:00:00

abstract：:The US EPA and the California Air Resources Board studied the exposures of 51 residents of Los Angeles, CA to 25 volatile organic chemicals in air and drinking water in February and July of 1987. Participants carried a personal air monitor consisting of a Tenax cartridge and a small sampling pump for two consecutive 1...

journal_title：Toxicology and industrial health

authors： Wallace LA

更新日期：1991-09-01 00:00:00

abstract：:The actual stage of the development of Kosovo is characterized by the concerning levels of environmental pollution and the serious health problems attributed to the emission of pollutants into air, soil and water. In this context, river pollution is one of the main threats due to the discharge of untreated urban and i...

journal_title：Toxicology and industrial health

authors： Alija AJ,Bresgen N,Bojaxhi E,Krenn M,Bajraktari ID,Eckl PM

更新日期：2018-08-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:Holothuria polii (Delle Chiaje, 1823) (Holothuriidae) is a sea cucumber inhabiting Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal, antibacterial and antiparasitic effects. The present study aims to elucidate the structure of the bioactive material of H. polii for pharmacologica...

journal_title：Toxicology and industrial health

authors： Omran NE,Khedr AM

更新日期：2015-01-01 00:00:00

abstract：:Orange B, a pyrazolone dye used to color frankfurter and sausage casings, was given in distilled drinking water to pregnant Osborne-Mendel rats throughout gestation. Assessed on the basis of fluid consumption, the dose levels of 0, 0.05, 0.1, 0.2, and 0.4% corresponded to daily Orange B consumption of 0, 67.5, 129.6, ...

journal_title：Toxicology and industrial health

authors： Collins TF,Black TN,Ruggles DI

更新日期：1995-07-01 00:00:00

abstract：:Medicinal plants are increasingly being projected as suitable alternative source for the treatment of various diseases. However, toxic effects resulting from therapeutic bismuth compounds are still documented in animals and humans. This study described the genetic effects of five common lichen species and compared the...

journal_title：Toxicology and industrial health

authors： Geyikoglu F,Turkez H,Aslan A

更新日期：2007-09-01 00:00:00

abstract：:Lead (Pb) is one of several environmental pollutants that adversely affect human health by producing toxicity at the tissue level. The aim of the study was to understand the effects of Pb on the metabolic profiles of liver and gastrocnemius muscle of mice in relation to carbohydrate and fat metabolisms. Swiss albino m...

journal_title：Toxicology and industrial health

authors： Das P,Pal S,Basu S

更新日期：2020-07-01 00:00:00

abstract：:This study reports on airborne exposure levels and soil concentrations of lead in regard to abatement of a steel structure (water tank). The tank was de-leaded by abrasive sand blasting. The ball of the tank had a lead surface level that exceeded the Environmental Protection Agency (EPA) definition of lead-based paint...

journal_title：Toxicology and industrial health

authors： Lange JH

更新日期：2002-02-01 00:00:00

abstract：:As one of the main components of risk assessment, exposure assessment plays a key role in evaluating risk. Many different scenarios can be developed to estimate the risk from exposure to chemicals such as persistent organic pollutants (POPs). The US Food and Drug Administration (FDA)'s Center for Food Safety and Appli...

journal_title：Toxicology and industrial health

authors： Jensen E,Egan S,Canady R,Bolger P

更新日期：2001-06-01 00:00:00

abstract：:Chronic exposure to jet fuel has been shown to have adverse effects on human liver function, to cause emotional dysfunction, to cause abnormal electroencephalograms, to cause shortened attention spans, and to decrease sensorimotor speed. Due to the decision by the United States Air Force to implement the widespread us...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,Robledo RF,Witten M

更新日期：1997-09-01 00:00:00