Abstract:
:The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group, along with the relevant literature data, to show that in-vivo antioxidants increase the systems reliability in other tacks. For example, butylated hydroxytoluene can prevent production of O2*- in mitochondria, whereas flavonoids can induce expression of antioxidant enzymes, SOD and catalase. We suggest that the timely introduction of antioxidants can provide the beneficial physiological effects through the prophylactic reliability maintenance against reactive forms of oxygen via the hormonal system.
journal_name
Toxicol Ind Healthjournal_title
Toxicology and industrial healthauthors
Koltover VKdoi
10.1177/0748233709103029subject
Has Abstractpub_date
2009-05-01 00:00:00pages
295-9issue
4-5eissn
0748-2337issn
1477-0393pii
25/4-5/295journal_volume
25pub_type
杂志文章,评审abstract::The effect of copper in form of copper sulphate (CuSO4 x 5 H2O) was studied in the bone marrow cells of rats of Wistar strain in an in vitro culture. Evident differences between tissue cultures of the bone marrow cells were observed between the control and experimental groups. In the experimental group, the CFU-F colo...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378900500617
更新日期:1989-12-01 00:00:00
abstract:INTRODUCTION:Spirometry is the main pulmonary function test routinely employed in the occupational medicine practice. Its interpretation depends on the choice of the theoretical reference values. Therefore, our objective was to retrospectively evaluate the differences in the spirometric interpretation according to the ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233720912059
更新日期:2020-02-01 00:00:00
abstract::In summary, we have described our method of treating phosgene inhalation injury. We have presented two serious cases in detail which demonstrate that survival was associated with aggressive therapy. Several points should be mentioned. The pulmonary edema and resulting fluid and foam production can be so copious as to ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378500100207
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVES:In this study, biological exposure indicators were used to assess the exposure of workers to cadmium (Cd), lead (Pb), manganese (Mn), and nickel (Ni) in nonferrous metal smelters. METHODS:A total of 273 male participants (178 exposed and 95 nonexposed control group), working in nonferrous metal foundries lo...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233715589262
更新日期:2016-10-01 00:00:00
abstract::In this paper, a description of olfactory anatomy is presented, followed by a brief review of modern procedures for testing olfactory function. Information from the sole study which has quantitatively examined olfactory function in patients with apparent multiple chemical sensitivity (MCS) is presented. In essence, th...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract::Recently, we have detailed a DNA alkaline unwinding assay (DAUA) that can be used to rapidly measure chemically induced strand breaks in mammalian cells (Daniel et al., 1985). In this paper we present further development of this assay, including: (1) studies on the relationship between DNA adducts and DNA strand break...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378900500506
更新日期:1989-10-01 00:00:00
abstract::Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational perio...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233714525497
更新日期:2016-06-01 00:00:00
abstract::Environmental pollution, primarily from industrialization, has caused significant adverse effects to humans, animals, and the ecosystem. Attempts have been made to reduce and prevent these pollutants through better waste management practices. Incineration is one such practice, which seeks to prevent adverse health imp...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:
更新日期:1996-03-01 00:00:00
abstract::Endothelial adhesion plays an important role in the process of atherosclerosis, which is regulated by endothelial adhesion molecules and chemoattractant molecules. In some areas of China, citreoviridin (CIT) is considered a risk factor for the development of atherosclerosis. Here, we investigated the role of CIT in ad...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713483194
更新日期:2015-03-01 00:00:00
abstract::Holothuria polii (Delle Chiaje, 1823) (Holothuriidae) is a sea cucumber inhabiting Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal, antibacterial and antiparasitic effects. The present study aims to elucidate the structure of the bioactive material of H. polii for pharmacologica...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712466135
更新日期:2015-01-01 00:00:00
abstract::In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1191/0748233705th224oa
更新日期:2005-09-01 00:00:00
abstract::The inhalation toxicity of methanol and toluene was investigated in rats. Young Sprague Dawley rats of both sexes were exposed to vapors of methanol (300 ppm, 3000 ppm), toluene (30 ppm, 300 ppm) or methanol/toluene (300/30 ppm, 300/300 ppm, 3000/30 ppm, and 3000/300 ppm) six hrs per day, five days/week for four weeks...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823379401000310
更新日期:1994-05-01 00:00:00
abstract::Yoghurt is a popular dairy product in Iran because of its beneficial influence on human health and nutritional value. Aflatoxin M1 (AFM1) is the metabolite of potential carcinogen aflatoxin B1, which can contaminate milk through the feed and is not eliminated by common processing heat treatment. An analytical method u...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233710394236
更新日期:2011-08-01 00:00:00
abstract::The aim of this study was to evaluate the effect of resveratrol on kidney tissue of rats exposed to cigarette smoke. Forty adult male Wistar Albino rats were divided into four groups. Animals in group 1 was the control group. For 6 weeks, group 2 was exposed to cigarette smoke; group 3 received daily intraperitoneal i...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233709346755
更新日期:2009-09-01 00:00:00
abstract::Organophosphate poisoning is a life-threatening condition, which is being responsible for the symptoms due to cholinergic effects. Clinical status and blood levels of cholinesterase are used its diagnosis. While atropine and pralidoxime (PAM) appear as essential medications, hemofiltration treatments and lipid solutio...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712462478
更新日期:2014-06-01 00:00:00
abstract::Glycidyl methacrylate (GMA; CAS no. 106-91-2) is a chemical monomer used in the manufacture of dental resins, can coatings and polymers. GMA has demonstrated toxicity to the ocular, digestive, respiratory and dermal systems. Human exposure occurs mainly in the workplace, but it can also happen through food. Although t...
journal_title:Toxicology and industrial health
pub_type: 信件
doi:10.1177/0748233720957816
更新日期:2020-12-01 00:00:00
abstract::Endocrine disrupting chemicals (EDCs) are defined as exogenous substances that can alter the development and functioning of the endocrine system. The Wnt signaling pathway is an evolutionarily conserved pathway consisting of proteins that transmit cell-to-cell receptors through cell surface receptors, regulating impor...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/0748233719898989
更新日期:2020-01-01 00:00:00
abstract::This study was designed to determine if long-term exposure to high doses of methoxychlor (M) would alter pituitary or testicular endocrine functions in either an estrogenic or antiandrogenic manner. Weanling male Long-Evans hooded rats were dosed daily with M (po) at 0, 200, 300, or 400 mg kg-1 day-1 for 10 months. Me...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823379901500105
更新日期:1999-01-01 00:00:00
abstract::Pesticides are omnipresent in environment, water, fruits, and vegetables and are considered as risk factors for human health. Consumers are mainly exposed to pesticides through diet, and the main question to be answered concerns the impact of such exposure on health. In this study, we developed a mouse model to mimic ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233714548207
更新日期:2016-07-01 00:00:00
abstract::The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233707076810
更新日期:2007-05-01 00:00:00
abstract::Sorption of three pesticides on geologic material ranging in organic carbon content from 0.33 to 6.9 g kg-1 was measured in soil columns using a miscible displacement technique. An octanol-water partitioning model was shown to be inappropriate for predicting sorption of the less hydrophobic pesticides on the low organ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378800400306
更新日期:1988-09-01 00:00:00
abstract::In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233710387006
更新日期:2011-05-01 00:00:00
abstract::The aim of the present study was to assess and compare the individual adverse effects of bisphenol A (BPA) and octylphenol (OP) on the reproductive system of prepubertal male rats. Rats were exposed to BPA and OP at doses of 125 and 250 mg/kg/day, by gavage, for 90 days. At the end of the study, the testes, epididymis...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233715603847
更新日期:2017-02-01 00:00:00
abstract:STUDY OBJECTIVES:Asbestos bodies (ABs) form as asbestos fibers become coated by a cellular iron- and protein-rich matrix. ABs have been reported in lymph nodes and a few extrapulmonary sites, but no data exist as to their formation outside of the lung. It is not clear whether the AB found in these extrapulmonary areas ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1191/0748233701th090oa
更新日期:2001-02-01 00:00:00
abstract::Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liver failure, but therapeutic doses are believed to be safe. The purpose of this study is to investigate the effects of administration of subtoxic doses of APAP on liver and blood levels of insulin-like growth factor-1 (IGF-...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498439
更新日期:2016-01-01 00:00:00
abstract::In allelopathy, one plant suppresses the growth and development of other plant/plants by negatively affecting a variety of physiological and biochemical reactions. We checked the effects of methanolic extracts (allelochemical extracts) of Phytolacca latbenia (Moq.) H. Walter on antioxidant enzyme activities such as pe...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713483205
更新日期:2015-10-01 00:00:00
abstract::Paraquat has been shown to be a highly toxic compound for humans and animals, and many cases of acute poisoning and death have been reported over the past few decades. The present study was undertaken to evaluate comprehensively herbicides (Paraquat) and some plant extracts to biochemical aspects of Lymnaea natalensis...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498457
更新日期:2016-01-01 00:00:00
abstract::Diazinon (DZN) is one of the most widely used insecticides in agricultural pest control. Previous studies have shown that DZN may induce hepatotoxicity. Reactive oxygen species and apoptosis pathways are involved in the toxicity of DZN. Crocin, a constituent of saffron, has hepatoprotective effects due to its antioxid...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713475519
更新日期:2015-04-01 00:00:00
abstract::Cutting fluids can become contaminated with metals (e.g., nickel, Ni) and nitrosamines (e.g., N-nitrosodiethanolamine, NDELA) and there is concern that these classes of contaminants can modulate dermal disposition and ultimately the toxicity of cutting fluid additives, such as irritant biocides (e.g., triazine). Bioci...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1191/0748233705th229oa
更新日期:2005-10-01 00:00:00
abstract::Forty-five deaths from mesothelioma have occurred among production workers in an asbestos-cement factory. This analysis examines the fit of the cubic residence time model to the incidence of mesothelioma using a case-control method proposed by de Klerk and colleagues. The cubic residence time model was found to provid...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00