Effects of acrylamide graded doses on metallothioneins I and II induction and DNA fragmentation: Bochemical and histomorphological changes in the liver of adult rats.

abstract：:Lead (Pb) is one of several environmental pollutants that adversely affect human health by producing toxicity at the tissue level. The aim of the study was to understand the effects of Pb on the metabolic profiles of liver and gastrocnemius muscle of mice in relation to carbohydrate and fat metabolisms. Swiss albino m...

journal_title：Toxicology and industrial health

authors： Das P,Pal S,Basu S

更新日期：2020-07-01 00:00:00

abstract：:This study focuses on investigating the possible protective effect of sodium selenite (Na2SeO3) and/or vitamin E against mercuric chloride (HgCl2)-induced hepatotoxicity in rat. Male rats were given HgCl2 (1 mg/kg body weight (bw)) and HgCl2 plus Na2SeO3 (0.25 mg/kg bw) and/or vitamin E (100 mg/kg bw) daily via gavage...

journal_title：Toxicology and industrial health

authors： Uzunhisarcikli M,Aslanturk A,Kalender S,Apaydin FG,Bas H

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of resveratrol on kidney tissue of rats exposed to cigarette smoke. Forty adult male Wistar Albino rats were divided into four groups. Animals in group 1 was the control group. For 6 weeks, group 2 was exposed to cigarette smoke; group 3 received daily intraperitoneal i...

journal_title：Toxicology and industrial health

authors： Kuruş M,Ugras M,Esrefoglu M

更新日期：2009-09-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:Exposure to the humidifier disinfectant, polyhexamethylene guanidine phosphate (PHMG), in mists generated from ultrasonic humidifiers was studied in a simulation chamber and apartment rooms. PHMG is suspected as a causative agent of lung disease in Korea residences. In the simulation-chamber study, the amount of disin...

journal_title：Toxicology and industrial health

authors： Lee JH,Yu IJ

更新日期：2017-11-01 00:00:00

abstract：:The following is a review of some of the work we have done since 2004 regarding the importance of molds and their mycotoxins in the phenomenon of sick building syndrome (SBS). In these studies we showed that the macrocyclic trichothecene mycotoxins (MTM) of Stachybotrys chartarum (SC) are easily dissociated from the s...

journal_title：Toxicology and industrial health

authors： Straus DC

更新日期：2009-10-01 00:00:00

abstract：:Orange B, a pyrazolone dye used to color frankfurter and sausage casings, was given in distilled drinking water to pregnant Osborne-Mendel rats throughout gestation. Assessed on the basis of fluid consumption, the dose levels of 0, 0.05, 0.1, 0.2, and 0.4% corresponded to daily Orange B consumption of 0, 67.5, 129.6, ...

journal_title：Toxicology and industrial health

authors： Collins TF,Black TN,Ruggles DI

更新日期：1995-07-01 00:00:00

abstract：:Adult female Swiss Webster and B6C3F1 mice received distilled water only or water containing 0.1, 1.0, 10, 100 or 1000 ppb of aldicarb daily for 34 days. The target concentration of aldicarb present in the 10 ppb dosing solution was analytically verified on a daily basis as was its stability over a 48-hr period. To de...

journal_title：Toxicology and industrial health

authors： Thomas PT,Ratajczak HV

更新日期：1988-09-01 00:00:00

abstract：:The morphological consequences of chronic exposition to low doses of cadmium (Cd) in the Leydig cells population were investigated in 40 sexually mature male mice at morphological and ultrastructural levels. Animals were orally exposed to cadmium (0.015 g/L of CdCl(2) in drinking water) for 3, 6, 12 and 18 months and ...

journal_title：Toxicology and industrial health

authors： Blanco A,Moyano R,Molina López AM,Blanco C,Flores-Acuña R,García-Flores JR,Espada M,Monterde JG

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to analyze the biochemical alterations in the gills of Venus verrucosa under exposure for 6 days to three doses of lambda-cyhalothrin (λ-cyh) (100, 250, and 500 µg L-1). Malondialdehyde, lipid hydroperoxide, and hydrogen peroxide levels in the gills of treated groups increased. λ-Cyh exposure...

journal_title：Toxicology and industrial health

authors： Fouzai C,Trabelsi W,Rabeh I,Bejaoui S,Telahigue K,El Cafsi M,Soudani N

更新日期：2020-11-01 00:00:00

abstract：:In dry etching processes--one of the sources of potential exposure to toxic wastes in the semiconductor industry--complex mixtures of inorganic and organic compounds arise from reactions between feed stock gases (BCl3/Cl2), top layers (aluminium photoresist), and the carrier gas (N2). Two different fractions of the co...

journal_title：Toxicology and industrial health

authors： Bauer S,Wolff I,Werner N,Hoffmann P,Herzschuh R,Oemus K,Rath FW,Voigt R

更新日期：1992-05-01 00:00:00

abstract：:Microcystins (MCs) are the most potent toxins that can be produced by cyanobacteria in drinking water supplies. This study investigated the abundance of toxin-producing algae in 11 drinking water treatment plants (DWTPs). A total of 26 different algal taxa were identified in treated water, from which 12% were blue gre...

journal_title：Toxicology and industrial health

authors： Ibrahim WM,Salim EH,Azab YA,Ismail AH

更新日期：2016-10-01 00:00:00

abstract：:Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...

journal_title：Toxicology and industrial health

authors： Holder JW

更新日期：2008-11-01 00:00:00

abstract：:Cucumbers grown in two different greenhouses were exposed to mancozeb and carbaryl at different times. The effects of 10-day preharvest period, water and detergent washing, peeling, predetermined storage period at 4°C (refrigeration), and fermentation on the reduction of residue levels in the plant tissues were invest...

journal_title：Toxicology and industrial health

authors： Saeedi Saravi SS,Shokrzadeh M

更新日期：2016-06-01 00:00:00

abstract：:Reports about vanadium (V) inhalation toxicity on the hematopoietic system, specifically about coagulation are limited. Therefore, we decided to evaluate the effects of V with a complete blood count and morphologic analysis of platelets on blood smears. CD-1 male mice inhaled V2O5 0.02 M 1 h twice weekly over 12 weeks...

journal_title：Toxicology and industrial health

authors： González-Villalva A,Fortoul TI,Avila-Costa MR,Piñón-Zarate G,Rodriguez-Laraa V,Martínez-Levy G,Rojas-Lemus M,Bizarro-Nevarez P,Díaz-Bech P,Mussali-Galante P,Colin-Barenque L

更新日期：2006-04-01 00:00:00

abstract：:At the present time, the following parameters can be recommended for "early diagnosis" of phosgene overexposure: Phosgene indicator paper badges, to be worn by all persons involved in handling phosgene (these badges permit immediate estimation of the exposure dose in each individual case); Observation of the initial i...

journal_title：Toxicology and industrial health

authors： Diller WF

更新日期：1985-10-01 00:00:00

abstract：:The present paper summarizes the proposed time-dependent sensitization (TDS) and partial limbic kindling model for illness from low-level chemicals; reviews and critiques prior studies on CNS aspects of multiple chemical sensitivity (MCS); and outlines possible experimental approaches to future studies. TDS is the pro...

journal_title：Toxicology and industrial health

authors： Bell IR

更新日期：1994-07-01 00:00:00

abstract：:As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These pro...

journal_title：Toxicology and industrial health

authors： Wilbur S,Wohlers D,Paikoff S,Keith LS,Faroon O

更新日期：2008-06-01 00:00:00

abstract：:Atrazine is a commonly used herbicide that has previously been implicated as an endocrine-disrupting compound. Previous studies have shown that estrogenic endocrine-disrupting compounds affect the development of the heart, cartilage, and bone in zebrafish ( Danio rerio). To determine whether atrazine has effects simil...

journal_title：Toxicology and industrial health

authors： Walker BS,Kramer AG,Lassiter CS

更新日期：2018-05-01 00:00:00

abstract：:Cyclophosphamide (CP) is an alkylating agent that has been considered effective for cancer treatment. Lycopene, the pigment in tomato fruits, has beneficial effect in the treatment of some diseases. The goal of this study is to evaluate the protective effect of lycopene alone or combined with melatonin (Mel) in inhibi...

journal_title：Toxicology and industrial health

authors： Al-Malki AL

更新日期：2014-07-01 00:00:00

abstract：:Endothelial adhesion plays an important role in the process of atherosclerosis, which is regulated by endothelial adhesion molecules and chemoattractant molecules. In some areas of China, citreoviridin (CIT) is considered a risk factor for the development of atherosclerosis. Here, we investigated the role of CIT in ad...

journal_title：Toxicology and industrial health

authors： Hou H,Zhou R,Jia Q,Li Q,Kang L,Jiao P,Li D,Jiang B

更新日期：2015-03-01 00:00:00

abstract：:Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 mont...

journal_title：Toxicology and industrial health

authors： Hopper DL,Kernan WJ,Lloyd WE

更新日期：1986-07-01 00:00:00

abstract：:This study was realized to investigate the possible beneficial effect of thymoquinone (TQ), the major active component of volatile oil of Nigella sativa seeds, against lead (Pb)-induced inhibition of rat testicular functions. Adult rats were randomized into four groups: a control group receiving no treatment; a Pb gro...

journal_title：Toxicology and industrial health

authors： Mabrouk A,Ben Cheikh H

更新日期：2016-06-01 00:00:00

abstract：:In the present study, we attempted to elucidate the induction of autophagy in rat hepatocytes by a low concentration of mercury. Hepatocytes treated with different doses of mercuric chloride (HgCl2; 1, 2.5, 5 and 10 µM) and at different time intervals (0 min, 30 min, 1 h, 2 h and 4 h) show autophagic cell death only a...

journal_title：Toxicology and industrial health

authors： Chatterjee S,Ray A,Mukherjee S,Agarwal S,Kundu R,Bhattacharya S

更新日期：2014-08-01 00:00:00

abstract：:Phthalates are abundantly produced plasticizers, and dibutyl phthalate (DBP) is the most widely used derivative in various consumer products and medical devices. This study was conducted to further explore the potential testicular toxicity of DBP in adult rats and to elucidate the underlying mechanisms. Adult male alb...

journal_title：Toxicology and industrial health

authors： Aly HA,Hassan MH,El-Beshbishy HA,Alahdal AM,Osman AM

更新日期：2016-08-01 00:00:00

abstract：:The present study was designed to evaluate the effect of Plantago major Linnaeus (PM) extract on serum total sialic acid (TSA), lipid-bound sialic acid (LSA), some trace elements (copper (Cu), zinc (Zn) and iron) and mineral levels (magnesium, calcium and sodium) in Wistar albino rat administrated 7,12-dimethylbenz(a)...

journal_title：Toxicology and industrial health

authors： Oto G,Ekin S,Ozdemir H,Levent A,Berber I

更新日期：2012-05-01 00:00:00

abstract：:Exposure estimates produced using predictive exposure assessment methods are associated with a number of uncertainties that relate to the inherent variability of the values for a given input parameter (e.g., body weight, ingestion rate, inhalation rate) and to unknowns concerning the representativeness of the assumpti...

journal_title：Toxicology and industrial health

authors： Whitmyre GK,Driver JH,Ginevan ME,Tardiff RG,Baker SR

更新日期：1992-09-01 00:00:00

abstract：:A preliminary study of dermal and respiratory exposure to chlorpyrifos (Dursban TC) during structural treatments was conducted with eight workers from a commercial pest control company. The compound was applied by sub-slab and soil injection to four houses, with each application involving two workers. Crawl space appl...

journal_title：Toxicology and industrial health

authors： Fenske RA,Elkner KP

更新日期：1990-05-01 00:00:00

abstract：:This report reviews the literature on the impact of exposure to trichloroethylene (TCE) on human health. Special emphasis is given to the health effects reported in excess of national norms by participants in the TCE Subregistry of the Volatile Organic Compounds Registry of the National Exposure Registries--persons wi...

journal_title：Toxicology and industrial health

authors： Gist GL,Burg JR

更新日期：1995-05-01 00:00:00

abstract：:Organophosphate poisoning is a life-threatening condition, which is being responsible for the symptoms due to cholinergic effects. Clinical status and blood levels of cholinesterase are used its diagnosis. While atropine and pralidoxime (PAM) appear as essential medications, hemofiltration treatments and lipid solutio...

journal_title：Toxicology and industrial health

authors： Karakus A,Celik MM,Karcioglu M,Tuzcu K,Erden ES,Zeren C

更新日期：2014-06-01 00:00:00