Antiapoptotic and proliferative activity of curcumin on ovarian follicles in mice exposed to whole body ionizing radiation.

abstract：:Zinc oxide nanoparticles (ZnO NPs) are important nanomaterials with myriad applications and in widespread use. The main aim of this study was to evaluate the direct effect of ZnO NPs on steroidogenesis by considering mouse testicular Leydig cells (TM3) as an in vitro model system. The uptake, intracellular behaviour, ...

journal_title：Toxicology and industrial health

authors： Bara N,Kaul G

更新日期：2018-08-01 00:00:00

abstract：:Methiocarb (MC) is a widely used carbamate pesticide in agriculture and health programs. Although the main molecular mechanism of carbamate toxicity involves acetylcholinesterase inhibition, studies have also implicated the induction of oxidative stress. Therefore, the present study was aimed to evaluate the effect of...

journal_title：Toxicology and industrial health

authors： Ozden S,Catalgol B,Gezginci-Oktayoglu S,Karatug A,Bolkent S,Alpertunga B

更新日期：2013-02-01 00:00:00

abstract：:Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 mont...

journal_title：Toxicology and industrial health

authors： Hopper DL,Kernan WJ,Lloyd WE

更新日期：1986-07-01 00:00:00

abstract：:Wild alligators exposed to persistent organochlorine contaminants, municipal waste compounds, and contemporary-use herbicides exhibit reproductive alterations that are thought to be caused by endocrine disruption. This study tests the hypothesis that these alterations, at least in part, result from exposure of alligat...

journal_title：Toxicology and industrial health

authors： Crain DA,Spiteri ID,Guillette LJ Jr

更新日期：1999-01-01 00:00:00

abstract：:Recently, we have detailed a DNA alkaline unwinding assay (DAUA) that can be used to rapidly measure chemically induced strand breaks in mammalian cells (Daniel et al., 1985). In this paper we present further development of this assay, including: (1) studies on the relationship between DNA adducts and DNA strand break...

journal_title：Toxicology and industrial health

authors： Daniel FB,Chang LW,Schenck KM,DeAngelo AB,Skelly MF

更新日期：1989-10-01 00:00:00

abstract：:This study reports on airborne exposure levels and soil concentrations of lead in regard to abatement of a steel structure (water tank). The tank was de-leaded by abrasive sand blasting. The ball of the tank had a lead surface level that exceeded the Environmental Protection Agency (EPA) definition of lead-based paint...

journal_title：Toxicology and industrial health

authors： Lange JH

更新日期：2002-02-01 00:00:00

abstract：:The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...

journal_title：Toxicology and industrial health

authors： Mumtaz MM,Durkin PR

更新日期：1992-11-01 00:00:00

abstract：:Young adult CD-1 male mice were housed in individual cages throughout the study. Groups of 10 to 20 mice were given gradually increasing doses of delta-9-tetrahydrocannabinol (THC) at 6.25 to 25 mg/kg i.p., trifluoperazine (TFP) at 6 to 12 mg/kg p.o., phenobarbital sodium (PS) at 20 to 35 mg/kg p.o., morphine sulfate ...

journal_title：Toxicology and industrial health

authors： Yen-Koo HC,Tocus EC,Balazs T

更新日期：1989-12-01 00:00:00

abstract：:A preliminary study of dermal and respiratory exposure to chlorpyrifos (Dursban TC) during structural treatments was conducted with eight workers from a commercial pest control company. The compound was applied by sub-slab and soil injection to four houses, with each application involving two workers. Crawl space appl...

journal_title：Toxicology and industrial health

authors： Fenske RA,Elkner KP

更新日期：1990-05-01 00:00:00

abstract：:Trans-1,1,1,4,4,4-hexafluoro-2-butene (HFO-133mzz-E) is an odorless gas that finds uses as a foam transfer agent, heat transfer fluid, and specialty gas. The acute 4-h LC50 (in rats) for HFO-133mzz-E is > 17,000 ppm; it was not an eye or dermal irritant in 3- and 13-week repeated-dose inhalation studies in rats at con...

journal_title：Toxicology and industrial health

authors：

更新日期：2019-03-01 00:00:00

abstract：:The aim of this study was to evaluate the global scientific output of neurotoxicity of nanoparticles (NPs) and explore their hot spots and research trends. Articles about the neurotoxicity of NPs between 2008 and 2017 were taken from the Web of Science Core Collection database. The VOSviewer was used to analyze annual...

journal_title：Toxicology and industrial health

authors： Su B,Guan Q,Yu S

更新日期：2018-12-01 00:00:00

abstract：:At the present time, the following parameters can be recommended for "early diagnosis" of phosgene overexposure: Phosgene indicator paper badges, to be worn by all persons involved in handling phosgene (these badges permit immediate estimation of the exposure dose in each individual case); Observation of the initial i...

journal_title：Toxicology and industrial health

authors： Diller WF

更新日期：1985-10-01 00:00:00

abstract：:In the framework of a series of experiments conducted to evaluate the carcinogenic effects of oxygenated gasoline additives, MTBE was analyzed in an oral lifetime carcinogenicity study using 8-week-old male and female Sprague-Dawley rats. These experiments were part of a large research project on gasoline carcinogenic...

journal_title：Toxicology and industrial health

authors： Belpoggi F,Soffritti M,Maltoni C

更新日期：1995-03-01 00:00:00

abstract：:1,2-Dichloropropane (1,2-DCP), a solvent, which is the main component of the cleaner used in the offset printing companies in Japan, is suspected to be the causative agent of bile duct cancer, which has been recently reported at high incidence in those offset printing workplaces. While there are some reports about the...

journal_title：Toxicology and industrial health

authors： Yanagiba Y,Suzuki T,Suda M,Hojo R,Gonzalez FJ,Nakajima T,Wang RS

更新日期：2016-09-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...

journal_title：Toxicology and industrial health

authors： Maina G,Manzari M,Palmas A,Passini V,Filon FL

更新日期：2007-02-01 00:00:00

abstract：:Chloropentafluorobenzene (CPFB) has been identified as a candidate simulant for nonpersistent chemical warfare agents. Acute toxicity studies have shown that CPFB has limited adverse effects on laboratory animals. A 21-day inhalation study of rats and mice to 2.5, 0.8, and 0.25 mg CPFB/liter resulted in reduced weight...

journal_title：Toxicology and industrial health

authors： Kinkead ER,Bunger SK,Kimmel EC,Flemming CD,Wall HG,Grabau JH

更新日期：1991-07-01 00:00:00

abstract：:As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These pro...

journal_title：Toxicology and industrial health

authors： Wilbur S,Wohlers D,Paikoff S,Keith LS,Faroon O

更新日期：2008-06-01 00:00:00

abstract：:Aflatoxin B1 (AFB1) is a toxic compound commonly found as a contaminant in human food. It is carcinogenic due its potential in inducing the oxidative stress and distortion of the most antioxidant enzymes. Since black tea possesses strong antioxidant activity, it protects cells and tissues against oxidative stress. Cur...

journal_title：Toxicology and industrial health

authors： Alm-Eldeen AA,Mona MH,Shati AA,El-Mekkawy HI

更新日期：2015-12-01 00:00:00

abstract：:The US EPA and the California Air Resources Board studied the exposures of 51 residents of Los Angeles, CA to 25 volatile organic chemicals in air and drinking water in February and July of 1987. Participants carried a personal air monitor consisting of a Tenax cartridge and a small sampling pump for two consecutive 1...

journal_title：Toxicology and industrial health

authors： Wallace LA

更新日期：1991-09-01 00:00:00

abstract：:The purpose of this study is to follow-up the distribution, lethality percentile doses (LDs) and bioaccumulation of aluminium oxide nanoparticles (Al2O3-NPs, average diameter 9.83 ± 1.61 nm) in some tissues of male albino rats, and to evaluate its genotoxicity to the brain tissues, during acute and sublethal experimen...

journal_title：Toxicology and industrial health

authors： Morsy GM,El-Ala KS,Ali AA

更新日期：2016-02-01 00:00:00

abstract：:Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational perio...

journal_title：Toxicology and industrial health

authors： Razavinasab M,Moazzami K,Shabani M

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：:Maneb is a dithiocarbamate fungicide that contains manganese. Dithiocarbamates are considered to be chemicals of low toxicity. An experimental group (n = 10) received maneb (obtained from Hoecht-Shering) at a concentration of 250 ppm in distilled water five days a week (treatment time is three weeks). It was orally ad...

journal_title：Toxicology and industrial health

authors： Deveci E

更新日期：2006-10-01 00:00:00

abstract：:Lead is a heavy metal that affects various systems and organs in the body, especially the nervous system. In this study, the in vivo and in vitro effects of lead on neurons were analyzed. We divided mouse pups into three groups based on the concentration of lead exposure: the control group, the low-dose group, and the...

journal_title：Toxicology and industrial health

authors： Duan Y,Peng L,Shi H,Jiang Y

更新日期：2017-11-01 00:00:00

abstract：:We report two cases of formaldehyde-containing hair straighteners causing new onset asthma. Formaldehyde has been reported to cause asthma in other settings. The purpose of this article is to examine two cases of asthma in hairdressers exposed to hair smoothing products and to review the relevant literature on formald...

journal_title：Toxicology and industrial health

authors： Dahlgren JG,Talbott PJ

更新日期：2018-04-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnO NPs) are produced in high tonnage each year; they are widely used in consumer and industrial products, also now finding applications in bioimaging and drug delivery. In the present study, comparison between ZnO NPs (39 nm) and its bulk/micron form (particle size = 5 µm) on liver function ...

journal_title：Toxicology and industrial health

authors： Moatamed ER,Hussein AA,El-Desoky MM,Khayat ZE

更新日期：2019-10-01 00:00:00

abstract：:Lead (Pb) is a toxic metal that induces a wide range of biochemical and physiological effects in humans. Oxidative damage has been proposed as a possible mechanism involved in Pb toxicity. The current study was carried out to evaluate the antioxidant activities of zinc (Zn) supplement against lead acetate-induced kidn...

journal_title：Toxicology and industrial health

authors： Soussi A,Gargouri M,El Feki A

更新日期：2018-07-01 00:00:00

abstract：:The negative health effects caused by lead (Pb) exposure are widely recognized; however, the molecular mechanisms remain unknown. The aim of this study was to assess the effect of occupational Pb exposure on telomere length and to investigate the potential mechanisms leading to telomere shortening. A cohort of 334 mal...

journal_title：Toxicology and industrial health

authors： Pawlas N,Płachetka A,Kozłowska A,Mikołajczyk A,Kasperczyk A,Dobrakowski M,Kasperczyk S

更新日期：2016-12-01 00:00:00

abstract：:Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...

journal_title：Toxicology and industrial health

authors： Holder JW

更新日期：2008-11-01 00:00:00

abstract：:Malathion can be ingested, inhaled, or absorbed through the skin, but acute toxicity is maximized when administered orally. Intravenous lipid emulsion (ILE) treatment is used as a new therapeutic method in cases of systemic toxicity caused by some lipid soluble agents. This study aimed to examine the potential treatme...

journal_title：Toxicology and industrial health

authors： Uysal M,Karaman S

更新日期：2018-02-01 00:00:00