Abstract:
:This investigation used a two-source capture-recapture method (CRM) for determining ascertainment and undercounts of non-national priority listed hazardous waste sites in the states of Arizona, Maine and Pennsylvania. These findings suggest that ascertainment of hazardous waste sites vary greatly, with some more accurate (i.e., Maine) than others (i.e., Pennsylvania). These data suggest that nontraditional manufacturing states (e.g., Maine) have a higher ascertainment rate than traditional manufacturing states (e.g., Pennsylvania). These results indicate that resources for locating hazardous waste sites should be more heavily allotted to industrialized areas. We suggest that the CRM is a convenient, low cost and effective method for determining (1) the accuracy of previous estimates, and (2) the number of sites in a locale with 95% confidence intervals along with an estimate of the undercount. Findings suggest that estimates of hazardous waste sites should use the CRM to determine and improve accuracy.
journal_name
Toxicol Ind Healthjournal_title
Toxicology and industrial healthauthors
Lange JH,Chang YF,LaPorte RE,Mastrangelo Gdoi
10.1191/0748233703th179oasubject
Has Abstractpub_date
2003-07-01 00:00:00pages
109-13issue
2-6eissn
0748-2337issn
1477-0393journal_volume
19pub_type
杂志文章abstract::This paper describes the development and implementation of physiologically-based pharmacokinetic (PB-Pk) models to examine the disposition of xenobiotics and their bioactivation. In a PB-Pk model, the structure of the model is based, to as great extent as practicable, on the actual physiological and biochemical struct...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/074823379401000101
更新日期:1994-01-01 00:00:00
abstract::This experiment is designed to investigate the positive effects of commercial nanosilver compound on blood parameters in experimental aflatoxicosis in broiler chickens. For this, 270 one-day-old broiler chickens were randomly divided into six treatment groups with three replicates. The experimental groups were group A...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712452611
更新日期:2014-03-01 00:00:00
abstract::Significant numbers of chemicals have been shown to be carcinogenic in mouse liver although they do not exhibit carcinogenic activity in other organs or tissues of mice or rats. This review focuses on the reasons for the unique susceptibility of the mouse liver to these carcinogens and the extent to which the carcinog...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378500100421
更新日期:1985-12-01 00:00:00
abstract::Phthalates are abundantly produced plasticizers, and dibutyl phthalate (DBP) is the most widely used derivative in various consumer products and medical devices. This study was conducted to further explore the potential testicular toxicity of DBP in adult rats and to elucidate the underlying mechanisms. Adult male alb...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233714566877
更新日期:2016-08-01 00:00:00
abstract::The concentrations of heavy metals (cadmium (Cd), copper (Cu), nickel (Ni), lead (Pb) and zinc (Zn)) were measured in hepatopancreas and muscle of a commercial shrimp (Metapenaeus affinis), in the muscle, liver and gills of two fish species (Thryssa vitrirostris and Johnius belangerii) and in the sediment samples take...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713475498
更新日期:2015-06-01 00:00:00
abstract::Lead (Pb) is one of several environmental pollutants that adversely affect human health by producing toxicity at the tissue level. The aim of the study was to understand the effects of Pb on the metabolic profiles of liver and gastrocnemius muscle of mice in relation to carbohydrate and fat metabolisms. Swiss albino m...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233720937196
更新日期:2020-07-01 00:00:00
abstract::The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. Exposure of mice to JP-8 for 1 h/day resulted in immediate secretion ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233708090908
更新日期:2007-11-01 00:00:00
abstract::Polycyclic aromatic hydrocarbons have mutagenic and carcinogenic properties and some of them are classified as probable or possible human carcinogens. Aim of this study was to evaluate the genotoxic risk in workers exposed to diesel exaust. Environmental and biological monitoring exposure to polycyclic aromatic hydroc...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233707077436
更新日期:2007-02-01 00:00:00
abstract::The purpose of this study is to follow-up the distribution, lethality percentile doses (LDs) and bioaccumulation of aluminium oxide nanoparticles (Al2O3-NPs, average diameter 9.83 ± 1.61 nm) in some tissues of male albino rats, and to evaluate its genotoxicity to the brain tissues, during acute and sublethal experimen...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498449
更新日期:2016-02-01 00:00:00
abstract::The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712469654
更新日期:2015-02-01 00:00:00
abstract::Cyclophosphamide (CP) is an alkylating agent that has been considered effective for cancer treatment. Lycopene, the pigment in tomato fruits, has beneficial effect in the treatment of some diseases. The goal of this study is to evaluate the protective effect of lycopene alone or combined with melatonin (Mel) in inhibi...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712459916
更新日期:2014-07-01 00:00:00
abstract::The aim of the present study was to assess the influence of curcumin on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Sprague Dawley rats were divided into three groups: sham-operated (SH), PH, and PH + curcumin; each group contains eight animals. The rats in curcumin-treated groups wer...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712469658
更新日期:2015-02-01 00:00:00
abstract::The developmental toxicity of 2,4-Pentanedione (2,4-PD; CAS No. 123-54-6), a widely used industrial chemical, was investigated by vapour exposure, because of its widespread use, and potential for human exposure. Timed-pregnant Fischer 344 rats were exposed on gestational days (gd) 6 to 15 inclusive to analytically mea...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823379000600308
更新日期:1990-05-01 00:00:00
abstract::'Toxicant-induced loss of tolerance' (or TILT) describes a two-step disease process in which (1) certain chemical exposures, e.g., indoor air contaminants, chemical spills, or pesticide applications, cause certain susceptible persons to lose their prior natural tolerance for common chemicals, foods, and drugs (initiat...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/074823379901500302
更新日期:1999-04-01 00:00:00
abstract::Chloroethane (CE) gas carcinogenicity is analyzed and determined from a National Toxicology Program (NTP) bioassay where an inhalation concentration of 15,000 ppm CE gas in air produced the highest incidence of an uncommon-to-rare tumor ever observed by the NTP. Persistently inhaled CE produces endometrial cancers in ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233708100371
更新日期:2008-11-01 00:00:00
abstract::The aim of the present study was to determine the effects of extremely low-frequency magnetic field (ELF-MF) on accumulation of manganese (Mn) in the kidney, liver and brain of rats. A total of 40 rats were randomly divided into eight groups. Four control groups received 0, 3.75, 15 and 60 mg Mn per kg body weight ora...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713480204
更新日期:2015-06-01 00:00:00
abstract::The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712472526
更新日期:2015-03-01 00:00:00
abstract::This study reports on airborne exposure levels and soil concentrations of lead in regard to abatement of a steel structure (water tank). The tank was de-leaded by abrasive sand blasting. The ball of the tank had a lead surface level that exceeded the Environmental Protection Agency (EPA) definition of lead-based paint...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1191/0748233702th127oa
更新日期:2002-02-01 00:00:00
abstract::Glycidyl methacrylate (GMA; CAS no. 106-91-2) is a chemical monomer used in the manufacture of dental resins, can coatings and polymers. GMA has demonstrated toxicity to the ocular, digestive, respiratory and dermal systems. Human exposure occurs mainly in the workplace, but it can also happen through food. Although t...
journal_title:Toxicology and industrial health
pub_type: 信件
doi:10.1177/0748233720957816
更新日期:2020-12-01 00:00:00
abstract::Paraphenylene diamine (PPD) hair dye poisoning is a common health problem in the Middle East and Indian subcontinent. It is the most common cause of suicide intent especially among females. We hereby present a 27-year-old female who presented with a clinical feature of PPD poisoning due to a suicidal attempt, and she ...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712448118
更新日期:2014-09-01 00:00:00
abstract::As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These pro...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/0748233708090910
更新日期:2008-06-01 00:00:00
abstract::The purpose of this study was to characterize the ultrastructural changes in the muscles of 2- and 6-month-old rats that were injected with 6-mercaptopurine monohydrate (6-MP) at 2 mg base/kg sc daily from 2 to 22 days of age. The earliest, usually subsarcolemmal alterations, were disorganization of fibrils at the Z-b...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378600200205
更新日期:1986-09-01 00:00:00
abstract::Elaeagnus angustifolia was analyzed for determination of metals, phytoconstituents, bactericidal, fungicidal and insecticidal effects and to explore its chemical and biological potential. The root, branches, leaves, stem bark and root bark parts of E. angustifolia were found to contain iron, lead, copper, cadmium, zin...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233713498459
更新日期:2016-01-01 00:00:00
abstract::The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712472525
更新日期:2015-04-01 00:00:00
abstract::Hepatocarcinogens are agents that increase the incidence of liver cancer in exposed animals or humans. It is now established that carcinogenic exposures have a widespread impact on the transcriptome, inducing both adaptive and adverse changes in the activities of genes and pathways. Chemical hepatocarcinogens have als...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233720922710
更新日期:2020-05-01 00:00:00
abstract::Hepatocytes that were isolated from 48 hr starved rats and incubated in Krebs-Henseleit bicarbonate buffer containing 10 microM A23187, 10mM l-lactate, 1mM pyruvate and 2mM l-lysine were found to contain 0.064 mumol of inorganic pyrophosphate/g wet wgt cells. Addition of either 20mM acetate or butyrate, which caused t...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/074823378600200308
更新日期:1986-09-01 00:00:00
abstract::The aryl hydrocarbon receptor (AHR) is one of the principal xenobiotic, nuclear receptor that is responsible for the early events involved in the transcription of a complex set of genes comprising the CYP450 gene family. In the present computational study, homology modelling and molecular docking were carried out with...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233712463774
更新日期:2014-09-01 00:00:00
abstract::Occupational exposure in a copper smelting industry may produce various adverse health effects including cancer. Despite a number of well-documented studies reporting an increased risk of cancer among copper smelter workers, the data on genotoxic effects in this industry are scarce. In view of the above, an assessment...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233711422735
更新日期:2012-10-01 00:00:00
abstract::Several classes of environmental contaminants have been claimed or suggested to possess endocrine-disrupting potency, which may result in reproductive problems and developmental disorders. In this paper the focus is on the multiple and interactive mechanisms of interference of persistent polyhalogenated aromatic hydro...
journal_title:Toxicology and industrial health
pub_type: 杂志文章,评审
doi:10.1177/074823379801400107
更新日期:1998-01-01 00:00:00
abstract::An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine (DFO), in removing cadmium from biological system. The potential efficiency of those chelators were investigated after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight dai...
journal_title:Toxicology and industrial health
pub_type: 杂志文章
doi:10.1177/0748233711403192
更新日期:2012-02-01 00:00:00