Professional exposure to urban stressors and effects on urinary metanephrines.

abstract：:Groups of five male and five female rats were fed diets containing from 0% to 2.5% di(2-ethylhexyl)terephthalate (DEHT) or 1.2% di(2-ethylhexyl)phthalate (DEHP) for 21 days. Feed consumption and body weight gains were collected and, at study termination, animals were examined for alterations in body weight, difference...

journal_title：Toxicology and industrial health

authors： Topping DC,Ford GP,Evans JG,Lake BG,O'Donoghue JL,Lockhart HB Jr

更新日期：1987-06-01 00:00:00

abstract：:The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6...

journal_title：Toxicology and industrial health

authors： Vena JE,Buck GM,Kostyniak P,Mendola P,Fitzgerald E,Sever L,Freudenheim J,Greizerstein H,Zielezny M,McReynolds J,Olson J

更新日期：1996-05-01 00:00:00

abstract：:Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to both sexes of rats and 0, 44, 88, 1...

journal_title：Toxicology and industrial health

authors： Matthews HB,Dixon D,Herr DW,Tilson H

更新日期：1990-01-01 00:00:00

abstract：:The effects of different methylmercury (MeHg) forms on the immune system and the hypothalamic pituitary adrenal (HPA) axis were assessed. The lymphocyte response to Concanavalin A (Con A) stimulation, blood levels of interleukin-6 (IL-6), adrenocorticotrophin hormone (ACTH), and corticosterone in the presence of diffe...

journal_title：Toxicology and industrial health

authors： Ortega HG,Lopez M,Takaki A,Huang QH,Arimura A,Salvaggio JE

更新日期：1997-01-01 00:00:00

abstract：:'Toxicant-induced loss of tolerance' (or TILT) describes a two-step disease process in which (1) certain chemical exposures, e.g., indoor air contaminants, chemical spills, or pesticide applications, cause certain susceptible persons to lose their prior natural tolerance for common chemicals, foods, and drugs (initiat...

journal_title：Toxicology and industrial health

authors： Miller CS

更新日期：1999-04-01 00:00:00

abstract：:Medicinal plants are increasingly being projected as suitable alternative source for the treatment of various diseases. However, toxic effects resulting from therapeutic bismuth compounds are still documented in animals and humans. This study described the genetic effects of five common lichen species and compared the...

journal_title：Toxicology and industrial health

authors： Geyikoglu F,Turkez H,Aslan A

更新日期：2007-09-01 00:00:00

abstract：:Pyrrolizidine alkaloid isoline is isolated from the traditional Chinese medicine Ligularia duciformis. Our previous reports have already demonstrated isoline-induced liver injury in mice. The present study is designed to observe the involvement of intracellular reduced glutathione (GSH) in isoline-induced cytotoxicity...

journal_title：Toxicology and industrial health

authors： Chen Y,Ji L,Xiong A,Yang L,Wang Z

更新日期：2013-07-01 00:00:00

abstract：:Cytochrome P450 2E1 (CYP2E1) can be induced by diabetes mellitus, nonalcoholic liver disease, and obesity. This study assessed the protective effects of three sulfur compounds, namely phenethyl isothiocyanate (PEITC), dimethyl trisulfide (DMTS), and sodium thiosulfate (STS), on acrylonitrile (ACN)-induced acute toxici...

journal_title：Toxicology and industrial health

authors： Li F,Lu R,Zhao T,Zhang X,Wang S,Xing G

更新日期：2019-05-01 00:00:00

abstract：:A preliminary study of dermal and respiratory exposure to chlorpyrifos (Dursban TC) during structural treatments was conducted with eight workers from a commercial pest control company. The compound was applied by sub-slab and soil injection to four houses, with each application involving two workers. Crawl space appl...

journal_title：Toxicology and industrial health

authors： Fenske RA,Elkner KP

更新日期：1990-05-01 00:00:00

abstract：:The objective of this study was to examine the potential of arsenate to induce cardiomyocyte cell death and to explore the cellular mechanisms of arsenate toxicity. Isolated cardiomyocytes in culture from embryonic chick hearts were treated with a pentavalent arsenic species (H3AsO4) or arsenate. Arsenate produced a s...

journal_title：Toxicology and industrial health

authors： Luong MW,Rabkin SW

更新日期：2009-04-01 00:00:00

abstract：:Several classes of environmental contaminants have been claimed or suggested to possess endocrine-disrupting potency, which may result in reproductive problems and developmental disorders. In this paper the focus is on the multiple and interactive mechanisms of interference of persistent polyhalogenated aromatic hydro...

journal_title：Toxicology and industrial health

authors： Brouwer A,Morse DC,Lans MC,Schuur AG,Murk AJ,Klasson-Wehler E,Bergman A,Visser TJ

更新日期：1998-01-01 00:00:00

abstract：:This experiment is designed to investigate the positive effects of commercial nanosilver compound on blood parameters in experimental aflatoxicosis in broiler chickens. For this, 270 one-day-old broiler chickens were randomly divided into six treatment groups with three replicates. The experimental groups were group A...

journal_title：Toxicology and industrial health

authors： Gholami-Ahangaran M,Zia-Jahromi N

更新日期：2014-03-01 00:00:00

abstract：:This study focuses on investigating the possible protective effect of sodium selenite (Na2SeO3) and/or vitamin E against mercuric chloride (HgCl2)-induced hepatotoxicity in rat. Male rats were given HgCl2 (1 mg/kg body weight (bw)) and HgCl2 plus Na2SeO3 (0.25 mg/kg bw) and/or vitamin E (100 mg/kg bw) daily via gavage...

journal_title：Toxicology and industrial health

authors： Uzunhisarcikli M,Aslanturk A,Kalender S,Apaydin FG,Bas H

更新日期：2016-09-01 00:00:00

abstract：:In dry etching processes--one of the sources of potential exposure to toxic wastes in the semiconductor industry--complex mixtures of inorganic and organic compounds arise from reactions between feed stock gases (BCl3/Cl2), top layers (aluminium photoresist), and the carrier gas (N2). Two different fractions of the co...

journal_title：Toxicology and industrial health

authors： Bauer S,Wolff I,Werner N,Hoffmann P,Herzschuh R,Oemus K,Rath FW,Voigt R

更新日期：1992-05-01 00:00:00

abstract：:Hepatocytes that were isolated from 48 hr starved rats and incubated in Krebs-Henseleit bicarbonate buffer containing 10 microM A23187, 10mM l-lactate, 1mM pyruvate and 2mM l-lysine were found to contain 0.064 mumol of inorganic pyrophosphate/g wet wgt cells. Addition of either 20mM acetate or butyrate, which caused t...

journal_title：Toxicology and industrial health

authors： Gitomer WL,Veech RL

更新日期：1986-09-01 00:00:00

abstract：:At the present time, the following parameters can be recommended for "early diagnosis" of phosgene overexposure: Phosgene indicator paper badges, to be worn by all persons involved in handling phosgene (these badges permit immediate estimation of the exposure dose in each individual case); Observation of the initial i...

journal_title：Toxicology and industrial health

authors： Diller WF

更新日期：1985-10-01 00:00:00

abstract：:In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...

journal_title：Toxicology and industrial health

authors： Ozkurkcugil C,Yilmaz MY,Ozkan L,Kokturk S,Isken T

更新日期：2011-05-01 00:00:00

abstract：:The bromoalkane, 1-bromopropane (1-BP), may damage the reproductive system though oxidative stress, while the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in regulating intracellular antioxidant levels against oxidative stress. This study explored the role of oxidativ...

journal_title：Toxicology and industrial health

authors： Yang G,Xiang Y,Zhou W,Zhong X,Zhang Y,Lin D,Huang X

更新日期：2020-12-11 00:00:00

abstract：:Trans-1,1,1,4,4,4-hexafluoro-2-butene (HFO-133mzz-E) is an odorless gas that finds uses as a foam transfer agent, heat transfer fluid, and specialty gas. The acute 4-h LC50 (in rats) for HFO-133mzz-E is > 17,000 ppm; it was not an eye or dermal irritant in 3- and 13-week repeated-dose inhalation studies in rats at con...

journal_title：Toxicology and industrial health

authors：

更新日期：2019-03-01 00:00:00

abstract：:The morphological consequences of chronic exposition to low doses of cadmium (Cd) in the Leydig cells population were investigated in 40 sexually mature male mice at morphological and ultrastructural levels. Animals were orally exposed to cadmium (0.015 g/L of CdCl(2) in drinking water) for 3, 6, 12 and 18 months and ...

journal_title：Toxicology and industrial health

authors： Blanco A,Moyano R,Molina López AM,Blanco C,Flores-Acuña R,García-Flores JR,Espada M,Monterde JG

更新日期：2010-09-01 00:00:00

abstract：:The effect of copper in form of copper sulphate (CuSO4 x 5 H2O) was studied in the bone marrow cells of rats of Wistar strain in an in vitro culture. Evident differences between tissue cultures of the bone marrow cells were observed between the control and experimental groups. In the experimental group, the CFU-F colo...

journal_title：Toxicology and industrial health

authors： Miszta H

更新日期：1989-12-01 00:00:00

abstract：:Acetaminophen (APAP) is widely used in the treatment of pain. Toxic doses of APAP cause acute liver failure, but therapeutic doses are believed to be safe. The purpose of this study is to investigate the effects of administration of subtoxic doses of APAP on liver and blood levels of insulin-like growth factor-1 (IGF-...

journal_title：Toxicology and industrial health

authors： Ozdemir D,Aksu I,Baykara B,Ates M,Sisman AR,Kiray M,Buyuk A,Uysal N

更新日期：2016-01-01 00:00:00

abstract：:Atmospheric acid precursor emissions in Asia are increasing at a significant rate. This is expected to continue for the next several years. This main purpose for this study is to observe the concentration variations of PM(2.5), PM(2.5-10), PM(10), total suspended particulates (TSP), atmospheric particulates, and dry d...

journal_title：Toxicology and industrial health

authors： Fang GC,Liu CK

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Polycyclic aromatic hydrocarbons (PAHs) are potent environmental pollutants. Benzo[α]pyrene (B[α]P) is the major compound of PAHs that acts by activating aryl hydrocarbon receptor (AhR) in cells. B[α]P is a known carcinogen and an immunotoxicant; however, its role with regard to nuclear factor of activated T ...

journal_title：Toxicology and industrial health

authors： Parsa M,Ostad SN,Moogahi SM,Bayat M,Ghahremani MH

更新日期：2016-07-01 00:00:00

abstract：:A comparative potency method for cancer risk assessment has been developed based on a constant relative potency hypothesis. This method was developed and tested using data from a battery of short-term mutagenesis bioassays, animal tumorigenicity data and human lung cancer risk estimations. This data base was developed...

journal_title：Toxicology and industrial health

authors： Lewtas J

更新日期：1985-12-01 00:00:00

abstract：:Acrylamide has been discovered in foods cooked at high temperature. A potentially harmful effect of this dietary component has been suggested by data indicating its association with increased breast cancer. This study investigated the potential effects of acrylamide in nontumorigenic breast cells by assessing expressi...

journal_title：Toxicology and industrial health

authors： Lyn-Cook LE Jr,Tareke E,Word B,Starlard-Davenport A,Lyn-Cook BD,Hammons GJ

更新日期：2011-02-01 00:00:00

abstract：:Retinyl esters are the storage form of vitamin A in skin, and retinyl palmitate (RP) accounts for the majority of the retinyl esters endogenously formed in skin. RP is also obtained exogenously through the topical application of cosmetic and skin care products that contain RP. There is limited information on the penet...

journal_title：Toxicology and industrial health

authors： Yan J,Wamer WG,Howard PC,Boudreau MD,Fu PP

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Hydrogen sulfide poisoning can cause severe myocardial injury, but the damage is subtle and can be easily misdiagnosed. This report presents the dynamic observation of myocardial injury associated with hydrogen sulfide poisoning. CASE REPORT:Two young men presented with symptoms of "lightning-like" death im...

journal_title：Toxicology and industrial health

authors： Mo W,Shen J,Huang X,Zhang Y,Zhang Z

更新日期：2020-10-01 00:00:00

abstract：:In the present study, we attempted to elucidate the induction of autophagy in rat hepatocytes by a low concentration of mercury. Hepatocytes treated with different doses of mercuric chloride (HgCl2; 1, 2.5, 5 and 10 µM) and at different time intervals (0 min, 30 min, 1 h, 2 h and 4 h) show autophagic cell death only a...

journal_title：Toxicology and industrial health

authors： Chatterjee S,Ray A,Mukherjee S,Agarwal S,Kundu R,Bhattacharya S

更新日期：2014-08-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnONP) are manufactured on a large scale and can be found in a variety of consumer products, such as sunscreens, lotions, paints and food additives. Few studies have been carried out on its genotoxic potential and related mechanisms in whole organisms. In the present study, the in vivo genoto...

journal_title：Toxicology and industrial health

authors： Carmona ER,Inostroza-Blancheteau C,Rubio L,Marcos R

更新日期：2016-12-01 00:00:00