Replication of Western equine encephalomyelitis virus. I. Some chemical and physical characteristics of viral ribonucleic acid.

abstract：:Cloned avian leukosis viral DNAs were mutagenized in the long terminal repeat, in the leader sequence for env mRNA, and at the poly-env junction. The effect of these mutations in the viral DNA upon its ability to direct virus production or env mRNA synthesis was analyzed by microinjecting the mutant DNAs into chicken ...

journal_title：Journal of virology

authors： Pugatsch T,Stacey DW

更新日期：1982-08-01 00:00:00

abstract：UNLABELLED:Influenza A viruses (IAVs) rely on host factors to support their life cycle, as viral proteins hijack or interact with cellular proteins to execute their functions. Identification and understanding of these factors would increase our knowledge of the molecular mechanisms manipulated by the viruses. In this s...

journal_title：Journal of virology

authors： Gao S,Wu J,Liu RY,Li J,Song L,Teng Y,Sheng C,Liu D,Yao C,Chen H,Jiang W,Chen S,Huang W

更新日期：2015-01-01 00:00:00

abstract：:Human group C adenoviruses cause an acute infection in respiratory epithelia and establish a long-term or persistent infection, possibly in lymphocytes. The mechanism by which this persistence is maintained is unknown; however, it would require that persistently infected lymphocytes not be deleted. The adenovirus geno...

journal_title：Journal of virology

authors： McNees AL,Garnett CT,Gooding LR

更新日期：2002-10-01 00:00:00

abstract：:The Borna disease virus (BDV) is the prototype member of the Bornaviridae, and it replicates in the cell nucleus. The BDV p24P and p40N proteins carry nuclear localization signals (NLS) and are found in the nuclei of infected cells. The BDV p10 protein does not have an NLS, but it binds with P and/or N and is transloc...

journal_title：Journal of virology

authors： Malik TH,Kishi M,Lai PK

更新日期：2000-04-01 00:00:00

abstract：:By means of both electron microscopy and plaque assay techniques, 10(-3)m Zn(2+) has been shown to reduce the adsorption rate of male-specific filamentous deoxyribonucleic acid bacteriophages to the tips of F pili. In contrast, 10(-3)m Zn(2+) did not affect the adsorption of male-specific ribonucleic acid phages to th...

journal_title：Journal of virology

authors： Ou JT,Anderson TF

更新日期：1972-10-01 00:00:00

abstract：:The herpes simplex virus type 1 (HSV-1) protease and its substrate, the assembly protein ICP35, are involved in virion maturation. Both proteins are encoded by a single open reading frame but are translated independently from 3'-coterminal mRNAs of different sizes and are in frame. The herpesvirus shell assembles arou...

journal_title：Journal of virology

authors： Robertson BJ,McCann PJ 3rd,Matusick-Kumar L,Preston VG,Gao M

更新日期：1997-02-01 00:00:00

abstract：UNLABELLED:Human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 encode auxiliary proteins that play important roles in viral replication, viral latency, and immune escape. The presence of auxiliary protein-encoding open reading frames (ORFs) in HTLV-3, the latest HTLV to be discovered, is unknown. Simian T-cell l...

journal_title：Journal of virology

authors： Turpin J,Journo C,Ko NL,Sinet F,Carpentier A,Galioot A,Edwards D,Vandamme AM,Gazzolo L,Duc Dodon M,Gessain A,Kashanchi F,Balansard I,Lacoste R,Mahieux R

更新日期：2015-01-15 00:00:00

abstract：:Chronic hepatitis C virus (HCV) infection is frequently associated with extrahepatic manifestations, including nonmalignant and malignant B-cell lymphoproliferative disorders. It has been reported that specific changes or recurring motifs in the amino acid sequence of the HCV hypervariable region 1 (HVR1) may be assoc...

journal_title：Journal of virology

authors： Bianchettin G,Bonaccini C,Oliva R,Tramontano A,Cividini A,Casato M,Merlini G,Silini E,Mondelli MU

更新日期：2007-05-01 00:00:00

abstract：:It was demonstrated that Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) were nonessential for B-lymphocyte growth transformation. We revisited this issue by producing a large quantity of EBER-deleted EBV by using an Akata cell system. Although the EBER-deleted virus efficiently infected B lymphocytes, its 50% tra...

journal_title：Journal of virology

authors： Yajima M,Kanda T,Takada K

更新日期：2005-04-01 00:00:00

abstract：:Interallelic complementation between certain temperature-sensitive mutants of gene 42 of bacteriophage T4 was demonstrated by measuring the incorporation of labeled thymine into DNA. ...

journal_title：Journal of virology

authors： Chiu CS,Greenberg GR

更新日期：1973-08-01 00:00:00

abstract：:Infectious pancreatic necrosis virus of fish, infectious bursal disease virus of chickens, Tellina virus and oyster virus of bivalve molluscs, and drosophila X virus of Drosophila melanogaster are naked icosahedral viruses with an electron microscopic diameter of 58 to 60 nm. The genome of each of these viruses consis...

journal_title：Journal of virology

authors： Dobos P,Hill BJ,Hallett R,Kells DT,Becht H,Teninges D

更新日期：1979-11-01 00:00:00

abstract：:The outcome of a viral infection is regulated in part by the complex coordination of viral and host interactions that compete for the control and optimization of virus replication. Severe acute respiratory syndrome coronavirus (SARS-CoV) intimately engages and regulates the host innate immune responses during infectio...

journal_title：Journal of virology

authors： Frieman M,Ratia K,Johnston RE,Mesecar AD,Baric RS

更新日期：2009-07-01 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is known to infect stem cells in the neonatal central nervous system. Here, we evaluated the effects of CVB3 infection on the major source and repository of stem cells, the bone marrow (BM). Viral genome was detectable in BM within 24 h of infection, and productive infection of BM cells was ev...

journal_title：Journal of virology

authors： Althof N,Whitton JL

更新日期：2013-03-01 00:00:00

abstract：:Apoptin, a viral death protein derived from chicken anemia virus, displays a number of tumor-specific behaviors. In particular, apoptin is phosphorylated, translocates to the nucleus, and induces apoptosis specifically in tumor or transformed cells, whereas it is nonphosphorylated and remains primarily inactive in the...

journal_title：Journal of virology

authors： Zhang YH,Kooistra K,Pietersen A,Rohn JL,Noteborn MH

更新日期：2004-09-01 00:00:00

abstract：:Using quantitative RNase protection assays, we have monitored the appearance of mRNAs generated during lytic infection of tightly synchronized murine cells by the autonomous parvovirus minute virus of mice. Our results demonstrate that transcripts from the P4 promoter can be detected prior to those from the P39 promot...

journal_title：Journal of virology

authors： Clemens KE,Pintel DJ

更新日期：1988-04-01 00:00:00

abstract：:A series of recombinant molecules were constructed which direct the expression of the easily assayed gene chloramphenicol acetyltransferase. We have used these recombinants to show that the 73/72-base-pair tandem repeat unit from the Moloney murine sarcoma virus long terminal repeat shares a number of properties with ...

journal_title：Journal of virology

authors： Laimins LA,Gruss P,Pozzatti R,Khoury G

更新日期：1984-01-01 00:00:00

abstract：UNLABELLED:Infection of the lower respiratory tract by influenza A viruses results in increases in inflammation and immune cell infiltration in the lung. The dynamic relationships among the lung microenvironments, the lung, and systemic host responses during infection remain poorly understood. Here we used extensive sy...

journal_title：Journal of virology

authors： Camp JV,Bagci U,Chu YK,Squier B,Fraig M,Uriarte SM,Guo H,Mollura DJ,Jonsson CB

更新日期：2015-09-01 00:00:00

abstract：:A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against c...

journal_title：Journal of virology

authors： Berhe G,Minet C,Le Goff C,Barrett T,Ngangnou A,Grillet C,Libeau G,Fleming M,Black DN,Diallo A

更新日期：2003-01-01 00:00:00

abstract：:Synthesis of viral ribonucleic acid (RNA) polymerase, maturation protein, and coat protein in Escherichia coli infected with bacteriophage R17 occurs mainly on polysomes containing four or more ribosomes. The 30S ribosomal subunits through trimer-size polysomes, which are associated with all of the R17-specific protei...

journal_title：Journal of virology

authors： Truden JL,Franklin RM

更新日期：1972-01-01 00:00:00

abstract：:Most eukaryotic initiation factors (eIFs) are required for internal translation initiation at the internal ribosome entry site (IRES) of picornaviruses. eIF4B is incorporated into ribosomal 48S initiation complexes with the IRES RNA of foot-and-mouth disease virus (FMDV). In contrast to the weak interaction of eIF4B w...

journal_title：Journal of virology

authors： Ochs K,Rust RC,Niepmann M

更新日期：1999-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is believed to begin with interactions between cell-free HCV and cell receptors that include CD81, scavenger receptor B1 (SR-B1), claudin-1 (CLDN1), and occludin (OCLN). In this study, we have demonstrated that HCV spreading from infected hepatocytes to uninfected hepatocytes leads to...

journal_title：Journal of virology

authors： Liu Z,He JJ

更新日期：2013-08-01 00:00:00

abstract：:Little is known about the mechanisms used by enveloped viruses to separate themselves from the cell surface at the final step of budding. However, small sequences in the Gag proteins of several retroviruses (L domains) have been implicated in this process. A sequence has been identified in the M proteins of rhabdoviru...

journal_title：Journal of virology

authors： Craven RC,Harty RN,Paragas J,Palese P,Wills JW

更新日期：1999-04-01 00:00:00

abstract：:A tumorigenic line of mouse cells transformed by the nononcogenic murine K papovavirus was established and characterized. Tumor-bearing animals produced antibody specific for K virus-transformed cells; the K virus T antiserum did not react with polyomavirus-transformed cells. Immunoprecipitation of the T antigen in th...

journal_title：Journal of virology

authors： Kanda T,Takemoto KK

更新日期：1984-06-01 00:00:00

abstract：:We investigated the effect of HLA class I alleles on clinical parameters for HIV-1 disease progression in the Japanese population, where two strongly protective alleles, HLA-B*57 and HLA-B*27, are virtually nonexistent. HLA-B alleles showed a dominant role, primarily through HLA-B*67:01 and the HLA-B*52:01-C*12:02 hap...

journal_title：Journal of virology

authors： Naruto T,Gatanaga H,Nelson G,Sakai K,Carrington M,Oka S,Takiguchi M

更新日期：2012-10-01 00:00:00

abstract：:The ability of the gamma(1)34.5 protein to suppress the PKR response plays a crucial role in herpes simplex virus pathogenesis. In this process, the gamma(1)34.5 protein associates with protein phosphatase 1 to form a large complex that dephosphorylates eIF-2alpha and thereby prevents translation shutoff mediated by P...

journal_title：Journal of virology

authors： Jing X,Cerveny M,Yang K,He B

更新日期：2004-07-01 00:00:00

abstract：:ts5, a temperature-sensitive mutant of influenza B virus, belongs to one of seven recombination groups. When the mutant infected MDCK cells at the nonpermissive temperature (37.5 degrees C), infectious virus was produced at very low levels compared with the yield at the permissive temperature (32 degrees C) and hemagg...

journal_title：Journal of virology

authors： Shibata S,Yamamoto-Goshima F,Maeno K,Hanaichi T,Fujita Y,Nakajima K,Imai M,Komatsu T,Sugiura S

更新日期：1993-06-01 00:00:00

abstract：:Proteasome inhibitors (e.g., bortezomib, MG132) are known to enhance adeno-associated virus (AAV) transduction; however, whether this results from pleotropic proteasome inhibition or off-target serine and/or cysteine protease inhibition remains unresolved. Here, we examined recombinant AAV (rAAV) effects of a new prot...

journal_title：Journal of virology

authors： Mitchell AM,Samulski RJ

更新日期：2013-12-01 00:00:00

abstract：:Understanding the role of host factors during lethal influenza virus infection is critical to deciphering the events that determine the fate of the host. One such factor is encoded by the Mx1 gene, which confers resistance to influenza virus infection. Here, we compared pathology and global gene expression profiles in...

journal_title：Journal of virology

authors： Cilloniz C,Pantin-Jackwood MJ,Ni C,Carter VS,Korth MJ,Swayne DE,Tumpey TM,Katze MG

更新日期：2012-03-01 00:00:00

abstract：:Posttranslational modification-oligomerization, phosphorylation, and proteolytic cleavage-of the human papillomavirus (HPV) E4 protein occurs as the infected keratinocytes migrate up through the suprabasal wart layers. It has been postulated that these events modify E4 function during the virus life cycle. In HPV type...

journal_title：Journal of virology

authors： Knight GL,Grainger JR,Gallimore PH,Roberts S

更新日期：2004-12-01 00:00:00

abstract：:The gamma(1)34.5 protein, a virulence factor of herpes simplex viruses, redirects protein phosphatase 1 to dephosphorylate the alpha subunit of translation initiation factor 2 (eIF2alpha). Additionally, it inhibits the induction of antiviral genes by TANK-binding kinase 1. Nevertheless, its precise role in vivo remain...

journal_title：Journal of virology

authors： Verpooten D,Feng Z,Valyi-Nagy T,Ma Y,Jin H,Yan Z,Zhang C,Cao Y,He B

更新日期：2009-12-01 00:00:00