Abstract:
:The Borna disease virus (BDV) is the prototype member of the Bornaviridae, and it replicates in the cell nucleus. The BDV p24P and p40N proteins carry nuclear localization signals (NLS) and are found in the nuclei of infected cells. The BDV p10 protein does not have an NLS, but it binds with P and/or N and is translocated to the nucleus. Hence, p10 may play a role in the replication of BDV in the cell nucleus. Here, we show that the P-binding domain is located in the N terminus of p10 and that S(3) and L(16) are important for the interaction.
journal_name
J Viroljournal_title
Journal of virologyauthors
Malik TH,Kishi M,Lai PKdoi
10.1128/jvi.74.7.3413-3417.2000subject
Has Abstractpub_date
2000-04-01 00:00:00pages
3413-7issue
7eissn
0022-538Xissn
1098-5514journal_volume
74pub_type
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