Naive T-cell depletion related to infection by X4 human immunodeficiency virus type 1 in poor immunological responders to highly active antiretroviral therapy.

abstract：:Posttranslational modification-oligomerization, phosphorylation, and proteolytic cleavage-of the human papillomavirus (HPV) E4 protein occurs as the infected keratinocytes migrate up through the suprabasal wart layers. It has been postulated that these events modify E4 function during the virus life cycle. In HPV type...

journal_title：Journal of virology

authors： Knight GL,Grainger JR,Gallimore PH,Roberts S

更新日期：2004-12-01 00:00:00

abstract：UNLABELLED:Many murine leukemia viruses (MLVs) are partially resistant to restriction by mouse APOBEC3 (mA3) and essentially fully resistant to induction of G-to-A mutations by mA3. In contrast, Vif-deficient HIV-1 (ΔVif HIV-1) is profoundly restricted by mA3, and the restriction includes high levels of G-to-A mutation...

journal_title：Journal of virology

authors： Nair S,Sanchez-Martinez S,Ji X,Rein A

更新日期：2014-04-01 00:00:00

abstract：:The current studies demonstrate complex and seemingly contradictory effects by gamma interferon (IFN-gamma) on Friend virus (FV) infection. Both temporal and tissue-specific effects were observed. During the first week of infection, IFN-gamma-deficiency caused increased levels of FV infection in multiple tissues. Surp...

journal_title：Journal of virology

authors： Stromnes IM,Dittmer U,Schumacher TN,Schepers K,Messer RJ,Evans LH,Peterson KE,Race B,Hasenkrug KJ

更新日期：2002-03-01 00:00:00

abstract：:The genome sequence of a hypervirulent novirhabdovirus, viral hemorrhagic septicemia virus (VHSV) French strain 23-75, was determined. Compared to the genome of the prototype Fil3 strain, a number of substitutions, deletions, and insertions were observed. Following the establishment of a plasmid-based minigenome repli...

journal_title：Journal of virology

authors： Biacchesi S,Lamoureux A,Mérour E,Bernard J,Brémont M

更新日期：2010-10-01 00:00:00

abstract：:A number of avocado (Persea americana) cultivars are known to contain high-molecular-weight double-stranded RNA (dsRNA) molecules for which a viral nature has been suggested, although sequence data are not available. Here we report the cloning and complete sequencing of a 13.5-kbp dsRNA virus isolated from avocado and...

journal_title：Journal of virology

authors： Villanueva F,Sabanadzovic S,Valverde RA,Navas-Castillo J

更新日期：2012-01-01 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne virus that infects upward of 300 million people annually and has the potential to cause fatal hemorrhagic fever and shock. While the parameters contributing to dengue immunopathogenesis remain unclear, the collapse of redox homeostasis and the damage induced by oxidative stress ...

journal_title：Journal of virology

authors： Ferrari M,Zevini A,Palermo E,Muscolini M,Alexandridi M,Etna MP,Coccia EM,Fernandez-Sesma A,Coyne C,Zhang DD,Marques ETA,Olagnier D,Hiscott J

更新日期：2020-11-23 00:00:00

abstract：:The large-particle fraction from the cytoplasm of chick embryo fibroblasts infected with Semliki Forest virus was found to catalyze the incorporation of the 5'-triphosphates of guanosine, adenine, cytidine, and uridine into an acid-insoluble alkali-labile product. The conditions affecting the preparation and assay of ...

journal_title：Journal of virology

authors： Martin EM,Sonnabend JA

更新日期：1967-02-01 00:00:00

abstract：:Paramyxoviruses initiate entry through the concerted action of the tetrameric attachment glycoprotein (HN, H, or G) and the trimeric fusion glycoprotein (F). The ectodomains of HN/H/G contain a stalk region important for oligomeric stability and for the F triggering resulting in membrane fusion. Paramyxovirus HN, H, a...

journal_title：Journal of virology

authors： Maar D,Harmon B,Chu D,Schulz B,Aguilar HC,Lee B,Negrete OA

更新日期：2012-06-01 00:00:00

abstract：:Aluminum (Al)-based salts are widely used adjuvants in ruminants and other species to strengthen the immune response elicited against vaccine antigen(s). However, they can lead to the formation of long-lasting granulomas composed of abundant activated macrophages. Small ruminant lentiviruses (SRLV) are widely distribu...

journal_title：Journal of virology

authors： Echeverría I,de Miguel R,Asín J,Rodríguez-Largo A,Fernández A,Pérez M,de Andrés D,Luján L,Reina R

更新日期：2020-12-22 00:00:00

abstract：:A monoclonal antibody, MAb vpg15, inhibits feline immunodeficiency virus (FIV) infection in tissue culture. The antibody is directed to a determinant of the feline cell surface marker, CD9, implying that CD9 may serve as a viral receptor or coreceptor in this system. In cells expressing CD9, MAb vpg15 markedly delayed...

journal_title：Journal of virology

authors： de Parseval A,Lerner DL,Borrow P,Willett BJ,Elder JH

更新日期：1997-08-01 00:00:00

abstract：:Recognition of virus infections by pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation associated gene 5 (MDA5), activates signaling pathways, leading to the induction of inflammatory cytokines that limit viral replication. To d...

journal_title：Journal of virology

authors： Guo H,Jiang D,Ma D,Chang J,Dougherty AM,Cuconati A,Block TM,Guo JT

更新日期：2009-01-01 00:00:00

abstract：:Analysis of the pronase-derived glycopeptides of isolated mumps virus glycoproteins revealed the presence of both complex and high-mannose-type oligosaccharides on the HN and F1 glycoproteins, whereas only high-mannose-type glycopeptides were detected on F2. Endoglycosidase F, a newly described glycosidase that cleave...

journal_title：Journal of virology

authors： Herrler G,Compans RW

更新日期：1983-08-01 00:00:00

abstract：:During lytic infection, herpes simplex virus subverts the host cell RNA polymerase II transcription machinery to efficiently express its own genome while repressing the expression of most cellular genes. The mechanism by which RNA polymerase II is directed to the viral delayed-early and late genes is still unresolved....

journal_title：Journal of virology

authors： Rice SA,Long MC,Lam V,Spencer CA

更新日期：1994-02-01 00:00:00

abstract：:While epidermal growth factor receptor (EGFR) has been shown to be important in the entry process for multiple viruses, including hepatitis C virus (HCV), the molecular mechanisms by which EGFR facilitates HCV entry are not well understood. Using the infectious cell culture HCV model (HCVcc), we demonstrate that the b...

journal_title：Journal of virology

authors： Diao J,Pantua H,Ngu H,Komuves L,Diehl L,Schaefer G,Kapadia SB

更新日期：2012-10-01 00:00:00

abstract：:Merkel cell polyomavirus (MCV) is a recently discovered human polyomavirus causing the majority of human Merkel cell carcinomas. We mapped a 71-bp minimal MCV replication core origin sufficient for initiating eukaryotic DNA replication in the presence of wild-type MCV large T protein (LT). The origin includes a poly(T...

journal_title：Journal of virology

authors： Kwun HJ,Guastafierro A,Shuda M,Meinke G,Bohm A,Moore PS,Chang Y

更新日期：2009-12-01 00:00:00

abstract：:Cytotoxic CD8+ T lymphocytes (CTL) directed against the matrix protein pp65 are major effectors in controlling infection against human cytomegalovirus (HCMV), a persistent virus of the Betaherpesvirus family. We previously suggested that cross-presentation of pp65 by nonpermissive dendritic cells (DCs) could overcome ...

journal_title：Journal of virology

authors： Arrode G,Boccaccio C,Abastado JP,Davrinche C

更新日期：2002-01-01 00:00:00

abstract：:Human T-cell lymphotropic virus type 1 (HTLV-1) is transmitted through a viral synapse and enters target cells via interaction with the glucose transporter GLUT1. Here, we show that Neuropilin-1 (NRP1), the receptor for semaphorin-3A and VEGF-A165 and a member of the immune synapse, is also a physical and functional p...

journal_title：Journal of virology

authors： Ghez D,Lepelletier Y,Lambert S,Fourneau JM,Blot V,Janvier S,Arnulf B,van Endert PM,Heveker N,Pique C,Hermine O

更新日期：2006-07-01 00:00:00

abstract：:The initiation of RNA transcription by the virion-bound RNA transcriptase of vesicular stomatitis virus has been examined. Multiple initiation sequences have been observed, two of which have been characterized (pppApCpGp... and pppGpCp...) suggestive of a transcription process which can start at different sites along ...

journal_title：Journal of virology

authors： Roy P,Bishop DH

更新日期：1973-04-01 00:00:00

abstract：:We have studied the functions of the intracellular RNAs of mouse mammary tumor virus (MMTV) by purification and translation in vitro. Two major size classes of MMTV RNA, 35S and 24S RNA, were isolated from MMTV-infected rat (XC) cells and cultured mammary tumor cells by preparative hybridization of whole cell or polya...

journal_title：Journal of virology

authors： Dudley JP,Varmus HE

更新日期：1981-07-01 00:00:00

abstract：:The RNA produced in vivo from bacteriophage phiX174 DNA has been analyzed by polyacrylamide-agarose gel electrophoresis and sedimentation in dimethyl sulfoxide gradients, and the results of Hayashi and Hayashi (1970) have been confirmed and extended. An efficient procedure for recovery of RNA from gels, followed by a ...

journal_title：Journal of virology

authors： Clements JB,Sinsheimer RL

更新日期：1975-01-01 00:00:00

abstract：:Preclinical studies have shown that gene transfer following readministration of viral vectors is often inefficient due to the presence of neutralizing antibodies. Vectors derived from ubiquitous human adenoviruses may have limited clinical use because preexisting humoral and cellular immunity is found in 90% of the po...

journal_title：Journal of virology

authors： Kremer EJ,Boutin S,Chillon M,Danos O

更新日期：2000-01-01 00:00:00

abstract：:To study the expression of the Autographa californica nuclear polyhedrosis virus (AcNPV) genome, intracellular virus-specific proteins and mRNAs were pulsed-labeled, extracted, and analyzed at 6-h intervals during the replicative cycle. Most RNAs were detected between 12 and 24 h postinfection (p.i.), but many continu...

journal_title：Journal of virology

authors： Rohel DZ,Faulkner P

更新日期：1984-06-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) is a recently described arterivirus responsible for disease in swine worldwide. Comparative sequence analysis of 3'-terminal structural genes of the single-stranded RNA viral genome revealed the presence of two genotypic classes of PRRSV, represented by the p...

journal_title：Journal of virology

authors： Nelsen CJ,Murtaugh MP,Faaberg KS

更新日期：1999-01-01 00:00:00

abstract：:Using gel mobility assays, we have detected two proteins that bind in the U3 region of the 1731 retrotransposon long terminal repeats (between positions -110 and -73) in nuclear extracts from Drosophila melanogaster cultured cells. The first one binds double-stranded DNA, whereas the other binds the mRNA-like strand i...

journal_title：Journal of virology

authors： Fourcade-Peronnet F,Codani-Simonart S,Best-Belpomme M

更新日期：1992-03-01 00:00:00

abstract：:Jaagsiekte sheep retrovirus (JSRV) is the causative agent of a transmissible lung cancer of sheep known as ovine pulmonary carcinoma. Recently, we have found that the expression of the JSRV envelope (Env) is sufficient to transform mouse NIH 3T3 cells in classical transformation assays. To further investigate the mech...

journal_title：Journal of virology

authors： Palmarini M,Maeda N,Murgia C,De-Fraja C,Hofacre A,Fan H

更新日期：2001-11-01 00:00:00

abstract：:Signal peptidase cleavage at the C-prM junction in the flavivirus structural polyprotein is inefficient in the absence of the cytoplasmic viral protease, which catalyzes cleavage at the COOH terminus of the C protein. The signal peptidase cleavage occurs efficiently in circumstances where the C protein is deleted or i...

journal_title：Journal of virology

authors： Stocks CE,Lobigs M

更新日期：1998-03-01 00:00:00

abstract：:We previously reported that mitogenic activation of porcine peripheral blood mononuclear cells resulted in production of porcine endogenous retrovirus(es) (PERV[s]) capable of productively infecting human cells (C. Wilson et al., J. Virol. 72:3082-3087, 1998). We now extend that analysis to show that additional passag...

journal_title：Journal of virology

authors： Wilson CA,Wong S,VanBrocklin M,Federspiel MJ

更新日期：2000-01-01 00:00:00

abstract：:The members of Flaviviridae utilize several endocytic pathways to enter a variety of host cells. Our previous work showed that classical swine fever virus (CSFV) enters porcine kidney (PK-15) cells through a clathrin-dependent pathway that requires Rab5 and Rab7. The entry mechanism for CSFV into other cell lines rema...

journal_title：Journal of virology

authors： Zhang YN,Liu YY,Xiao FC,Liu CC,Liang XD,Chen J,Zhou J,Baloch AS,Kan L,Zhou B,Qiu HJ

更新日期：2018-07-17 00:00:00

abstract：:C57BL mice (Fv-1b) develop a severe immunodeficiency disease following inoculation as adults with LP-BM5 murine leukemia virus (MuLV), a derivative of Duplan-Laterjet virus which contains B-tropic ecotropic and mink cell focus-inducing MuLVs and a putative defective genome which may be the proximal cause of disease. T...

journal_title：Journal of virology

authors： Hartley JW,Fredrickson TN,Yetter RA,Makino M,Morse HC 3rd

更新日期：1989-03-01 00:00:00

abstract：:The various strains of BK virus (BKV) exhibit a remarkable degree of heterogeneity in the transcriptional control region, which may affect the biological characteristics of a BKV strain. We describe the detection and sequencing of BKV control regions directly from urine samples and after propagation in cell culture. A...

journal_title：Journal of virology

authors： Sundsfjord A,Johansen T,Flaegstad T,Moens U,Villand P,Subramani S,Traavik T

更新日期：1990-08-01 00:00:00