Purification and translation of murine mammary tumor virus mRNA's.

abstract：:The structure of recombinant virus-like particles of malabaricus grouper nervous necrosis virus (MGNNV), a fish nodavirus isolated from the grouper Epinephelus malabaricus, was determined by electron cryomicroscopy (cryoEM) and three-dimensional reconstruction at 23-A resolution. The cryoEM structure, sequence compari...

journal_title：Journal of virology

authors： Tang L,Lin CS,Krishna NK,Yeager M,Schneemann A,Johnson JE

更新日期：2002-06-01 00:00:00

abstract：:Resistance to human immunodeficiency virus type 1 protease (HIV PR) inhibitors results primarily from the selection of multiple mutations in the protease region. Because many of these mutations are selected for the ability to decrease inhibitor binding in the active site, they also affect substrate binding and potenti...

journal_title：Journal of virology

authors： Dauber DS,Ziermann R,Parkin N,Maly DJ,Mahrus S,Harris JL,Ellman JA,Petropoulos C,Craik CS

更新日期：2002-02-01 00:00:00

abstract：:Among prion infections, two scenarios of prion spread are generally observed: (i) early lymphoid tissue replication or (ii) direct neuroinvasion without substantial antecedent lymphoid amplification. In nature, cervids are infected with chronic wasting disease (CWD) prions by oral and nasal mucosal exposure, and studi...

journal_title：Journal of virology

authors： Hoover CE,Davenport KA,Henderson DM,Denkers ND,Mathiason CK,Soto C,Zabel MD,Hoover EA

更新日期：2017-04-28 00:00:00

abstract：:Preferential integration into transcriptionally active regions of genomes has been observed for retroviral vectors based on gamma-retroviruses and lentiviruses. However, differences in the integration site preferences were detected, which might be explained by differences in viral components of the preintegration comp...

journal_title：Journal of virology

authors： Monse H,Laufs S,Kuate S,Zeller WJ,Fruehauf S,Uberla K

更新日期：2006-08-01 00:00:00

abstract：:The small envelope protein (E) plays a role of central importance in the assembly of coronaviruses. This was initially established by studies demonstrating that cellular expression of only E protein and the membrane protein (M) was necessary and sufficient for the generation and release of virus-like particles. To inv...

journal_title：Journal of virology

authors： Kuo L,Hurst KR,Masters PS

更新日期：2007-03-01 00:00:00

abstract：:The incorporation of (3)H-thymidine ((3)H-dT) into deoxyribonucleic acid (DNA) has been studied in uninfected confluent monolayer cultures of monkey kidney and mouse kidney cells, simian virus 40 (SV40)-infected cells, and in SV40-transformed mouse kidney cells. Radioautographic measurements revealed that during the p...

journal_title：Journal of virology

authors： Kit S,De Torres RA,Dubbs DR,Salvi ML

更新日期：1967-08-01 00:00:00

abstract：:Borna disease virus infection of neonatal rats results in a characteristic behavioral syndrome and apoptosis of subsets of neurons in the hippocampus and cerebellum (neonatal Borna disease [NBD]). The cellular mechanisms leading to neurodevelopmental damage in NBD have not been fully elucidated. Insights into this mod...

journal_title：Journal of virology

authors： Williams BL,Lipkin WI

更新日期：2006-09-01 00:00:00

abstract：:Several members of the APOBEC3 DNA cytosine deaminase family can potently inhibit Vif-deficient human immunodeficiency virus type 1 (HIV-1) by catalyzing cytosine deamination in viral cDNA and impeding reverse transcription. HIV-1 counteracts restriction with the virally encoded Vif protein, which targets relevant APO...

journal_title：Journal of virology

authors： Wang J,Shaban NM,Land AM,Brown WL,Harris RS

更新日期：2018-05-29 00:00:00

abstract：:We describe a modification of the polymerase chain reaction technique which allows amplification of cellular DNA adjacent to an integrated provirus given sequence information for the provirus only. The modified technique should be generally useful for studies of insertional mutagenesis and other situations in which on...

journal_title：Journal of virology

authors： Silver J,Keerikatte V

更新日期：1989-05-01 00:00:00

abstract：:The primary herpes simplex virus type 2 (HSV-2) latency-associated transcript (LAT) promoter influences LAT expression and rates of virus reactivation. We explored the biological importance of particular neuronally responsive regions within the promoter by creating new recombinant viruses bearing a targeted deletion (...

journal_title：Journal of virology

authors： Wang K,Pesnicak L,Straus SE

更新日期：1997-10-01 00:00:00

abstract：:Rio Bravo virus (RBV) is a member of the family Flaviviridae, genus Flavivirus. It belongs to a group of viruses in the genus with no known vector. In this report, we analyze the complete genome of the prototype RBV, strain M64. ...

journal_title：Journal of virology

authors： Volkova E,Tesh RB,Monath TP,Vasilakis N

更新日期：2012-04-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 genome encodes the Tax protein that plays essential regulatory roles in HTLV-1 replication and oncogenic transformation of T lymphocytes....

journal_title：Journal of virology

authors： Gao L,Harhaj EW

更新日期：2013-12-01 00:00:00

abstract：:The prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a formidable battle horse for the study of viral immunology, as well as viral persistence and associated diseases. Investigations with LCMV have uncovered basic mechanisms by which viruses avoid elimination by the host adaptive immune response. In ...

journal_title：Journal of virology

authors： Martínez-Sobrido L,Zúñiga EI,Rosario D,García-Sastre A,de la Torre JC

更新日期：2006-09-01 00:00:00

abstract：:The neutralizing activities of polyclonal antibodies and monoclonal antibodies (MAbs) obtained by immunization of mice with L1 virus-like particles (VLPs) were investigated by using pseudovirion infectivity assays for human papillomavirus type 16 (HPV-16), HPV-31, HPV-33, HPV-45, HPV-58, and HPV-59 to obtain a better ...

journal_title：Journal of virology

authors： Combita AL,Touzé A,Bousarghin L,Christensen ND,Coursaget P

更新日期：2002-07-01 00:00:00

abstract：:It is shown that the plasmid prophage P1 can be displaced by a superinfecting P1 phage in Escherichia coli recA(P1) lysogens. Six widely separated phage markers were used to distinguish between residual recombination and total substitution. It is further shown that superinfection of recA lysogens can lead to loss of b...

journal_title：Journal of virology

authors： Meurs E,D'Ari R

更新日期：1979-08-01 00:00:00

abstract：:A gene encoding a polypeptide with homology to mammalian vascular endothelial growth factors (VEGFs) has been discovered in the genome of orf virus (OV), a parapoxvirus that affects sheep and goats and, occasionally, humans. The gene is transcribed abundantly early in infection and is found immediately outside the inv...

journal_title：Journal of virology

authors： Lyttle DJ,Fraser KM,Fleming SB,Mercer AA,Robinson AJ

更新日期：1994-01-01 00:00:00

abstract：:Adenovirus type 2 (Ad2)-transformed hamster and rat cells are susceptible to lysis by natural killer (NK) cells from the host of origin and are nontumorigenic in immunocompetent hamsters and rats, respectively. These NK-cell-susceptible, virus-transformed cells are, however, highly tumorigenic in athymic (nude) mice--...

journal_title：Journal of virology

authors： Cook JL,Lewis AM Jr

更新日期：1987-07-01 00:00:00

abstract：:Transcriptional stimulatory properties of virus-encoded transactivators appear to be critical for viral gene expression and may be linked to cellular transformation in certain cases. Recently, the simian virus 40 (SV40) 17-kDa small-t antigen was shown to stimulate transcription of polymerase II and III genes in trans...

journal_title：Journal of virology

authors： Rajan P,Dhamankar V,Rundell K,Thimmapaya B

更新日期：1991-12-01 00:00:00

abstract：:Viral infection is associated with a vigorous inflammatory response characterized by cellular infiltration and release of the proinflammatory cytokines interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-alpha). In the present study, we identified a novel function of human cytomegalovirus (HCMV) that results in ...

journal_title：Journal of virology

authors： Jarvis MA,Borton JA,Keech AM,Wong J,Britt WJ,Magun BE,Nelson JA

更新日期：2006-06-01 00:00:00

abstract：:A temperature-sensitive mutant of adenovirus 31 was defective in formation of the DNA replication complex, suggesting the existence of a virus-coded protein necessary for the complex-formation. ...

journal_title：Journal of virology

authors： Suzuki E,Shimojo H

更新日期：1974-02-01 00:00:00

abstract：:The effect of herpes simplex virus type 2 (HSV-2) infection on the synthesis of DNA in human embryonic fibroblast cells was determined at temperatures permissive (37 C) and nonpermissive (42 C) for virus multiplication. During incubation of HSV-2 infected cultures at 42 C for 2 to 4 days or after shift-down from 42 to...

journal_title：Journal of virology

authors： Melvin P,Kucera LS

更新日期：1975-03-01 00:00:00

abstract：:A detailed restriction endonuclease map for the genome of Bacillus subtilis phage SP01 is presented. Sites of cleavage for the restriction enzymes BglII, EcoRI, HaeIII, and SalI were determined. This physical map showed that SP01 DNA was 140 kilobases in length and contained a repeated sequence of 12.4 kilobases at it...

journal_title：Journal of virology

authors： Pero J,Hannett NM,Talkington C

更新日期：1979-07-01 00:00:00

abstract：:Host cell tRNAs are recruited for use as primers to initiate reverse transcription in retroviruses. Human immunodeficiency virus type 1 (HIV-1) uses tRNA(Lys3) as the replication primer, whereas Rous sarcoma virus (RSV) uses tRNA(Trp). The nucleic acid (NA) chaperone function of the nucleocapsid (NC) domain of HIV-1 G...

journal_title：Journal of virology

authors： Rye-McCurdy TD,Nadaraia-Hoke S,Gudleski-O'Regan N,Flanagan JM,Parent LJ,Musier-Forsyth K

更新日期：2014-07-01 00:00:00

abstract：:Strains of Theiler's murine encephalomyelitis virus (TMEV) are divided into two subgroups, TO and GDVII. TMEV strains show subgroup-specific virus growth and cell tropism and induce subgroup-specific diseases. Using site-directed mutagenesis, we demonstrated that the amino acid at position 57 of the leader protein (L(...

journal_title：Journal of virology

authors： Takano-Maruyama M,Ohara Y,Asakura K,Okuwa T

更新日期：2006-12-01 00:00:00

abstract：:Cytotoxic CD8+ T lymphocytes (CTL) directed against the matrix protein pp65 are major effectors in controlling infection against human cytomegalovirus (HCMV), a persistent virus of the Betaherpesvirus family. We previously suggested that cross-presentation of pp65 by nonpermissive dendritic cells (DCs) could overcome ...

journal_title：Journal of virology

authors： Arrode G,Boccaccio C,Abastado JP,Davrinche C

更新日期：2002-01-01 00:00:00

abstract：:Determining how West Nile virus crosses the blood-brain barrier is critical to understanding the pathogenesis of encephalitis. Here, we show that ICAM-1(-/-) mice are more resistant than control animals to lethal West Nile encephalitis. ICAM-1(-/-) mice have a lower viral load, reduced leukocyte infiltration, and dimi...

journal_title：Journal of virology

authors： Dai J,Wang P,Bai F,Town T,Fikrig E

更新日期：2008-04-01 00:00:00

abstract：:Previously, the cyclophilin inhibitors cyclosporine (CsA) and alisporivir (ALV) were shown to inhibit the replication of diverse RNA viruses, including arteriviruses and coronaviruses, which both belong to the order Nidovirales In this study, we aimed to identify arterivirus proteins involved in the mode of action of ...

journal_title：Journal of virology

authors： de Wilde AH,Boomaars-van der Zanden AL,de Jong AWM,Bárcena M,Snijder EJ,Posthuma CC

更新日期：2019-08-28 00:00:00

abstract：:Carboxypeptidase D (gp180), one of many candidate receptors proposed for hepatitis B viruses (HBVs), was examined and found to be the actual cellular receptor for avian HBVs. This conclusion was based on the following observations: (i) gp180 was the only host protein that bound with high affinity to the pre-S ectodoma...

journal_title：Journal of virology

authors： Breiner KM,Urban S,Schaller H

更新日期：1998-10-01 00:00:00

abstract：:The cellular immune response contributes to viral clearance as well as to liver injury in acute and chronic hepatitis C virus (HCV) infection. An immunodominant determinant frequently recognized by liver-infiltrating and circulating CD8(+) T cells of HCV-infected patients is the HCV(NS3-1073) peptide CVNGVCWTV. Using ...

journal_title：Journal of virology

authors： Wedemeyer H,Mizukoshi E,Davis AR,Bennink JR,Rehermann B

更新日期：2001-12-01 00:00:00

abstract：:The hepatitis C virus (HCV) core protein is known to be a multifunctional protein, besides being a component of viral nucleocapsids. Previously, we have shown that the core protein binds to the cytoplasmic domain of lymphotoxin beta receptor, which is a member of tumor necrosis factor receptor (TNFR) family. In this s...

journal_title：Journal of virology

authors： Zhu N,Khoshnan A,Schneider R,Matsumoto M,Dennert G,Ware C,Lai MM

更新日期：1998-05-01 00:00:00