Complete genome sequence of a double-stranded RNA virus from avocado.

abstract：:A detailed kinetic and quantitative analysis of the early and late biosynthetic events undergone by the human immunodeficiency virus type 1 envelope protein expressed by a recombinant vaccinia virus was performed. Early folding events that occurred in the endoplasmic reticulum included disulfide bond formation (t1/2 a...

journal_title：Journal of virology

authors： Earl PL,Moss B,Doms RW

更新日期：1991-04-01 00:00:00

abstract：:BST-2/CD317/tetherin is a host factor that inhibits the release of HIV-1 and other unrelated viruses. A current model proposes that BST-2 physically tethers virions to the surface of virus-producing cells. The HIV-1-encoded Vpu protein effectively antagonizes the activity of BST-2. How Vpu accomplishes this task remai...

journal_title：Journal of virology

authors： Andrew AJ,Miyagi E,Strebel K

更新日期：2011-03-01 00:00:00

abstract：:We constructed a matched set of plasmids to investigate the interactions of essential core sequences of the simian virus 40 replication origin with flanking regulatory sequences. Deletions of either T-antigen-binding region I or the 21-base-pair repeated promoter elements reduced replication to 50 to 70% of wild-type ...

journal_title：Journal of virology

authors： DeLucia AL,Deb S,Partin K,Tegtmeyer P

更新日期：1986-01-01 00:00:00

abstract：:We analyzed the CD4+ T-lymphocyte responses to dengue, West Nile, and yellow fever viruses 4 months after immunization of a volunteer with an experimental live-attenuated dengue virus type 1 vaccine (DEN-1 45AZ5). We examined bulk culture proliferation to noninfectious antigens, determined the precursor frequency of s...

journal_title：Journal of virology

authors： Green S,Kurane I,Edelman R,Tacket CO,Eckels KH,Vaughn DW,Hoke CH Jr,Ennis FA

更新日期：1993-10-01 00:00:00

abstract：:Griffithsin, which binds N-linked glycans on gp120 to prevent HIV entry, has the most potent HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical preexposure prophylaxis. The current studies were designed to further assess its potential by exploring its activity against herpe...

journal_title：Journal of virology

authors： Nixon B,Stefanidou M,Mesquita PM,Fakioglu E,Segarra T,Rohan L,Halford W,Palmer KE,Herold BC

更新日期：2013-06-01 00:00:00

abstract：:Control of HIV-1 replication following nonsterilizing HIV-1 vaccination could be achieved by vaccine-elicited CD8(+) T-cell-mediated antiviral activity. To date, neither the functional nor the phenotypic profiles of CD8(+) T cells capable of this activity are clearly understood; consequently, little is known regarding...

journal_title：Journal of virology

authors： Freel SA,Lamoreaux L,Chattopadhyay PK,Saunders K,Zarkowsky D,Overman RG,Ochsenbauer C,Edmonds TG,Kappes JC,Cunningham CK,Denny TN,Weinhold KJ,Ferrari G,Haynes BF,Koup RA,Graham BS,Roederer M,Tomaras GD

更新日期：2010-05-01 00:00:00

abstract：:We have previously described a nonconditional mutant of avian sarcoma virus (SE21Q1b) which fails to package viral RNA (Gallis et al., Virology 94:146-161, 1979; Linial et al., Cell 15:1371-1381, 1978). Quail cells transformed by SE21Q1b contain normal amounts of intracellular viral mRNA's for src, env, and gag-pol an...

journal_title：Journal of virology

authors： Shank PR,Linial M

更新日期：1980-11-01 00:00:00

abstract：:We have investigated the molecular basis of biological differences observed among cell line-adapted isolates of the human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) and the simian immunodeficiency virus (SIV) in response to receptor binding by using a soluble form of CD4 (sCD4) as a receptor mimic. We find...

journal_title：Journal of virology

authors： Sattentau QJ,Moore JP,Vignaux F,Traincard F,Poignard P

更新日期：1993-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) RNA genome replicates within the ribonucleoprotein (RNP) complex in the modified membranous structures extended from endoplasmic reticulum. A proteomic analysis of HCV RNP complexes revealed the association of oxysterol binding protein (OSBP) as one of the components of these complexes. OSBP in...

journal_title：Journal of virology

authors： Amako Y,Sarkeshik A,Hotta H,Yates J 3rd,Siddiqui A

更新日期：2009-09-01 00:00:00

abstract：:The cell culture lines HTG2 and HTG3 were established from a transplantable hamster tumor induced by a murine sarcoma virus (strain Gz-MSV) after 17 and 60 in vivo passages, respectively. The viruses released by these two cell lines markedly differ in morphology, antigenic composition, infectivity, transforming abilit...

journal_title：Journal of virology

authors： Gazdar AF,Russell E,Sarma PS,Sarin PS,Hall W,Chopra HC

更新日期：1973-10-01 00:00:00

abstract：:Escherichia coli K-12 wild type and a uvrA mutant derivative were used to construct isogenic strains bearing one, two, three, or more phage lambda cI genomes and containing increasing concentration of lambda repressor as measured by in vitro operator DNA-binding assays. The survival and phage induction in response to ...

journal_title：Journal of virology

authors： Baluch J,Sussman R

更新日期：1978-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) efficiently drives proliferation of human primary B cells in vitro, a process relevant for human diseases such as infectious mononucleosis and posttransplant lymphoproliferative disease. Human B-cell proliferation is also driven by ligands of Toll-like receptors (TLRs), notably viral or bacter...

journal_title：Journal of virology

authors： Iskra S,Kalla M,Delecluse HJ,Hammerschmidt W,Moosmann A

更新日期：2010-04-01 00:00:00

abstract：:To model human immunodeficiency virus (HIV) perinatal transmission, we studied infection of simian-human immunodeficiency virus (SHIV) SF162P3 in 10 pregnant Macaca nemestrina females and their offspring. Four of nine infants born to and suckled by these dams had evidence of infection, a transmission rate of 44.4% (95...

journal_title：Journal of virology

authors： Jayaraman P,Zhu T,Misher L,Mohan D,Kuller L,Polacino P,Richardson BA,Bielefeldt-Ohmann H,Anderson D,Hu SL,Haigwood NL

更新日期：2007-01-01 00:00:00

abstract：:The fraction of the adenovirus type 5 genome expressed as mRNA in a rat cell line, 5RK, transformed by the HsuI-G restriction fragment was analyzed by saturation hybridization using separated strands of 32P-labeled HindIII-G fragment. It was found that 45 to 50% of G fragment (about 8 X 10(5) daltons) is expressed as ...

journal_title：Journal of virology

authors： Chinnadural G,Fujinaga K,Rho MH,van der Eb AJ,Green M

更新日期：1978-12-01 00:00:00

abstract：:The adenovirus major late promoter (MLP) is active during both the early and late phases of infection. During the early phase the activity of the MLP is similar to those of the other early viral promoters, but during the late phase the rate of transcription from the MLP becomes much greater by comparison. We report he...

journal_title：Journal of virology

authors： Leong K,Lee W,Berk AJ

更新日期：1990-01-01 00:00:00

abstract：:Autophagy is an intracellular degradation pathway that provides a host defense mechanism against intracellular pathogens. However, many viruses exploit this mechanism to promote their replication. This study shows that lytic induction of Epstein-Barr virus (EBV) increases the membrane-bound form of LC3 (LC3-II) and LC...

journal_title：Journal of virology

authors： Hung CH,Chen LW,Wang WH,Chang PJ,Chiu YF,Hung CC,Lin YJ,Liou JY,Tsai WJ,Hung CL,Liu ST

更新日期：2014-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) reorganizes intracellular membranes to establish sites of replication. How viral and cellular proteins target, bind, and rearrange specific membranes into the replication factory remains a mystery. We used a lentivirus-based RNA interference (RNAi) screening approach to identify the potential c...

journal_title：Journal of virology

authors： Chao TC,Su WC,Huang JY,Chen YC,Jeng KS,Wang HD,Lai MM

更新日期：2012-02-01 00:00:00

abstract：:Simian virus 40 (SV40)-transformed human cells (LN-SV) were fused with BALB/c peritoneal macrophages (BALB/c X LN-SV) and with C57BL peritoneal macrophages (C57BL X LN-SV) and hybrid clones, all of which had segregated human chromosomes and contained the entire complement of mouse chromosomes, were isolated. All 15 BA...

journal_title：Journal of virology

authors： Huebner K,Croce CM

更新日期：1976-06-01 00:00:00

abstract：:Characterization of immune responses induced by live attenuated simian immunodeficiency virus (SIV) strains may yield clues to the nature of protective immunity induced by this vaccine approach. We investigated the ability of CD8(+) T lymphocytes from rhesus macaques immunized with the live, attenuated SIV strain SIVm...

journal_title：Journal of virology

authors： Gauduin MC,Glickman RL,Means R,Johnson RP

更新日期：1998-08-01 00:00:00

abstract：:The relative antigenicity of the individual herpes simplex virus type 1 (KOS) glycoproteins gC and gB was analyzed in BALB/c mice by using KOS mutants altered in their ability to present these antigens on cell surface membranes during infection. The mutants employed were as follows: syn LD70 , a non-temperature-sensit...

journal_title：Journal of virology

authors： Glorioso J,Schröder CH,Kumel G,Szczesiul M,Levine M

更新日期：1984-06-01 00:00:00

abstract：:The RNA genome of influenza virus is transcribed and replicated by the viral RNA polymerase complex in the cell nucleus. We have generated green fluorescent protein (GFP)-tagged polymerase subunits to study the assembly of the polymerase complex. Our results show that individually expressed polymerase basic protein 1 ...

journal_title：Journal of virology

authors： Fodor E,Smith M

更新日期：2004-09-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) infection of mice provides a tractable small-animal system for assessing viral requirements for establishment of and reactivation from latency. The M2 gene product has no homology to any known proteins but has been shown to play a role in both the establishment of MHV68 latency and r...

journal_title：Journal of virology

authors： DeZalia M,Speck SH

更新日期：2008-08-01 00:00:00

abstract：:The alphavirus Semliki Forest virus (SFV) infects cells through low-pH-induced membrane fusion mediated by the E1 protein, a class II virus membrane fusion protein. During fusion, E1 inserts into target membranes via its hydrophobic fusion loop and refolds to form a stable E1 homotrimer. Mutation of a highly conserved...

journal_title：Journal of virology

authors： Chanel-Vos C,Kielian M

更新日期：2006-06-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS), caused by a novel coronavirus (CoV) known as SARS-CoV, is a contagious and life-threatening respiratory illness with pneumocytes as its main target. A full understanding of how SARS-CoV would interact with lung epithelial cells will be vital for advancing our knowledge of SARS...

journal_title：Journal of virology

authors： Tseng CT,Tseng J,Perrone L,Worthy M,Popov V,Peters CJ

更新日期：2005-08-01 00:00:00

abstract：:The ability of human immunodeficiency virus type 1 (HIV-1) to transduce nondividing cells is key to infecting terminally differentiated macrophages, which can serve as a long-term reservoir of HIV-1 infection. The mutation N57A in the viral CA protein renders HIV-1 cell cycle dependent, allowing examination of HIV-1 i...

journal_title：Journal of virology

authors： Fischer DK,Saito A,Kline C,Cohen R,Watkins SC,Yamashita M,Ambrose Z

更新日期：2019-04-17 00:00:00

abstract：:By using T1 oligonucleotide fingerprinting and mapping techniques, we analyzed the genomic structure of retroviruses produced by thymocytes and splenocytes of reciprocal bone marrow-and thymus-grafted chimeras. We found that the genetic factor(s) derived from NZB mice that suppresses the development of thymic leukemia...

journal_title：Journal of virology

authors： Datta SK,Thomas CY,Nicklas JA,Coffin JM

更新日期：1983-07-01 00:00:00

abstract：:Data showing that an apoptotic reaction (the exit into the cytoplasm and nucleolytic internucleosomal degradation of chromosomal DNA, compaction and fragmentation of chromatin, cellular shrinkage, and cytoplasmic blebbing) developed in a subline of HeLa-S3 cells upon nonpermissive poliovirus infection with either a gu...

journal_title：Journal of virology

authors： Tolskaya EA,Romanova LI,Kolesnikova MS,Ivannikova TA,Smirnova EA,Raikhlin NT,Agol VI

更新日期：1995-02-01 00:00:00

abstract：:Neurotropic coronavirus induces acute encephalomyelitis and demyelination in mice. Infection of BALB/c (H-2(d)) mice expressing a dominant negative gamma interferon (IFN-gamma) receptor specifically in oligodendrocytes was examined to determine the influence of IFN-gamma signaling on pathogenesis. Inhibition of IFN-ga...

journal_title：Journal of virology

authors： Parra GI,Bergmann CC,Phares TW,Hinton DR,Atkinson R,Stohlman SA

更新日期：2010-03-01 00:00:00

abstract：:Transcription of the terminal protein (TP) gene of Epstein-Barr virus (EBV) in Burkitt's lymphoma cells, in EBV-negative Burkitt's lymphoma cells converted with transformation-defective (P3HR1) and transformation-competent (B95-8, AG876) EBV strains, and in EBV-immortalized cell lines was studied. A TP1 cDNA probe spa...

journal_title：Journal of virology

authors： Zimber-Strobl U,Suentzenich KO,Laux G,Eick D,Cordier M,Calender A,Billaud M,Lenoir GM,Bornkamm GW

更新日期：1991-01-01 00:00:00

abstract：:To gain insight into the cellular regulation of bovine leukemia virus (BLV) trans activation, a lambda-gt11 cDNA library was constructed with mRNA isolated from a BLV-induced tumor and the recombinant proteins were screened with an oligonucleotide corresponding to the tax activation-responsive element (TAR). Two clone...

journal_title：Journal of virology

authors： Willems L,Kettmann R,Chen G,Portetelle D,Burny A,Derse D

更新日期：1992-02-01 00:00:00