Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections.

abstract：:The N termini of the capsid proteins VP1 and VP2 of adeno-associated virus (AAV) play important roles in subcellular steps of infection and contain motifs that are highly homologous to a phospholipase A(2) (PLA(2)) domain and nuclear localization signals (NLSs). To more clearly understand how virion components influen...

journal_title：Journal of virology

authors： Johnson JS,Li C,DiPrimio N,Weinberg MS,McCown TJ,Samulski RJ

更新日期：2010-09-01 00:00:00

abstract：:Herpes simplex virus (HSV) strains HSV type 1 (HSV-1) KOS and HSV-2 186 are representative of delayed and early shutoff strains, respectively, with regard to their ability to inhibit protein synthesis in Friend erythroleukemia cells. When these cells were simultaneously infected with HSV-1 KOS and HSV-2 186, HSV-1 KOS...

journal_title：Journal of virology

authors： Hill TM,Sadler JR,Betz JL

更新日期：1985-10-01 00:00:00

abstract：:A human cytomegalovirus (CMV) UL54 pol exonuclease domain II mutation, D413A, found in a clinical specimen, conferred ganciclovir (GCV) and cidofovir resistance but not foscarnet resistance when incorporated into laboratory strain T2294. After several passages without drug, mutation was observed in five of eight plaqu...

journal_title：Journal of virology

authors： Chou S,Marousek GI

更新日期：2008-01-01 00:00:00

abstract：:The binding of a recombinant soluble form of the measles virus (MV) hemagglutinin (sH) to cells expressing hybrid CD46/CD4 proteins was compared to that of purified virus. For binding of both ligands, both CD46 external short consensus repeats I and II (SCR I and II) in the natural order were essential. The addition o...

journal_title：Journal of virology

authors： Devaux P,Buchholz CJ,Schneider U,Escoffier C,Cattaneo R,Gerlier D

更新日期：1997-05-01 00:00:00

abstract：:Human immunodeficiency virus infection in humans and simian immunodeficiency virus (SIV) infection in rhesus macaques (RM) leads to a generalized loss of immune responses involving perturbations in T-cell receptor (TCR) signaling. In contrast, naturally SIV-infected sooty mangabeys (SM) remain asymptomatic and retain ...

journal_title：Journal of virology

authors： Bostik P,Wu P,Dodd GL,Villinger F,Mayne AE,Bostik V,Grimm BD,Robinson D,Kung HJ,Ansari AA

更新日期：2001-12-01 00:00:00

abstract：:Recent reports suggest that human genogroup II genotype 17 (GII.17) noroviruses are increasing in prevalence. We analyzed the evolutionary changes of three GII.17 capsid protruding (P) domains. We found that the GII.17 P domains had little cross-reactivity with antisera raised against the dominant GII.4 strains. X-ray...

journal_title：Journal of virology

authors： Singh BK,Koromyslova A,Hefele L,Gürth C,Hansman GS

更新日期：2015-12-23 00:00:00

abstract：:Two major outer envelope glycoproteins of Epstein-Barr virus, gp350 and gp220, are known to be encoded by 3.2- and 2.5-kilobase RNAs which map to the same DNA fragment (M. Hummel, D. Thorley-Lawson, and E. Kieff, J. Virol. 49:413-417). These RNAs have the same 5' and 3' ends. The larger RNA is encoded by a 2,777-base ...

journal_title：Journal of virology

authors： Beisel C,Tanner J,Matsuo T,Thorley-Lawson D,Kezdy F,Kieff E

更新日期：1985-06-01 00:00:00

abstract：:DNA polymerase activity was detected in each of eight preparations of concentrated human hepatitis B antigen (HBAg) rich in Dane particles prepared by high-speed centrifugation of antigen-positive human plasma and in none of seven control preparations prepared in the same way from HBAg-negative plasma. The incorporati...

journal_title：Journal of virology

authors： Kaplan PM,Greenman RL,Gerin JL,Purcell RH,Robinson WS

更新日期：1973-11-01 00:00:00

abstract：:ZAM is an env-containing member of the gypsy family of retrotransposons that represents a possible retrovirus of invertebrates. In this paper, we traced ZAM mobilization to get information about a potential path a retroelement may take to reach the germ line of its host. In situ hybridization on whole-mount tissues an...

journal_title：Journal of virology

authors： Leblanc P,Desset S,Giorgi F,Taddei AR,Fausto AM,Mazzini M,Dastugue B,Vaury C

更新日期：2000-11-01 00:00:00

abstract：:We have examined the exposure and conservation of antigenic epitopes on the surface envelope glycoproteins (gp120 and gp41) of 26 intact, native, primary human immunodeficiency virus type 1 (HIV-1) group M virions of clades A to H. For this, 47 monoclonal antibodies (MAbs) derived from HIV-1-infected patients were use...

journal_title：Journal of virology

authors： Nyambi PN,Mbah HA,Burda S,Williams C,Gorny MK,Nádas A,Zolla-Pazner S

更新日期：2000-08-01 00:00:00

abstract：:Inhibition of histone deacetylase (HDAC) activity induces growth arrest, differentiation, and, in certain cell types, apoptosis. FR901228, FK228, or depsipeptide, is an HDAC inhibitor effective in T-cell lymphomas. Adult T-cell leukemia (ATL) is caused by human T-cell leukemia virus type 1 (HTLV-1) and remains incurab...

journal_title：Journal of virology

authors： Mori N,Matsuda T,Tadano M,Kinjo T,Yamada Y,Tsukasaki K,Ikeda S,Yamasaki Y,Tanaka Y,Ohta T,Iwamasa T,Tomonaga M,Yamamoto N

更新日期：2004-05-01 00:00:00

abstract：:The hemagglutinin of fowl plague virus has been expressed in Spodoptera frugiperda (Sf9) cells and in Estigmene acrea cells by using a baculovirus vector. Structural analysis revealed that the endo-H-resistant N-glycans of HA from Sf9 cells were predominantly trimannosyl core oligosaccharides, whereas in E. acrea cell...

journal_title：Journal of virology

authors： Wagner R,Geyer H,Geyer R,Klenk HD

更新日期：1996-06-01 00:00:00

abstract：:Endogenous retroviruses, records of past retroviral infections, are ubiquitous in vertebrate genomes. On occasion, vertebrate hosts have co-opted retroviral genes for their own biological functions. Here, we perform a phylogenomic survey of retroviral gag gene homologs within vertebrate genomes and identify two ancien...

journal_title：Journal of virology

authors： Wang J,Gong Z,Han GZ

更新日期：2019-06-28 00:00:00

abstract：:Human papillomavirus (HPV) infection of the genital tract is common; however, only about 10 to 15% of infections persist, and approximately 10 to 15% of these persistent infections result in cancer. Basal epidermal stem cells are the presumed target cells for HPV infection, providing a reservoir of latently infected c...

journal_title：Journal of virology

authors： Woappi Y,Hosseinipour M,Creek KE,Pirisi L

更新日期：2018-05-14 00:00:00

abstract：:The characteristics of fusion of respiratory syncytial virus (RSV) with HEp-2 cells were studied by the R18 fluorescence dequenching assay of membrane fusion. A gradual increase in fluorescence intensity indicative of virion-cell fusion was observed when R18-labeled RSV was incubated with HEp-2 cells. Approximately 35...

journal_title：Journal of virology

authors： Srinivasakumar N,Ogra PL,Flanagan TD

更新日期：1991-08-01 00:00:00

abstract：:Vesicular stomatitis virus has the potential for very rapid evolution in the laboratory, but like many other arboviruses, it evolves at a relatively slow rate in the natural environment. Previous work showed that alternating replication in different cell types does not promote stasis. In order to determine whether oth...

journal_title：Journal of virology

authors： Zárate S,Novella IS

更新日期：2004-11-01 00:00:00

abstract：:The discovery that hepatitis B virus (HBV) integrates into host chromosomes raises the question of whether such viral DNA integration correlates directly with the activation of specific oncogenes or the inactivation of anti-oncogenes. To obtain insight into this problem, we randomly collected HBV integrant samples fro...

journal_title：Journal of virology

authors： Tokino T,Matsubara K

更新日期：1991-12-01 00:00:00

abstract：:An immunocompetent, permissive, small-animal model would be valuable for the study of human immunodeficiency virus type 1 (HIV-1) pathogenesis and for the testing of drug and vaccine candidates. However, the development of such a model has been hampered by the inability of primary rodent cells to efficiently support s...

journal_title：Journal of virology

authors： Tervo HM,Keppler OT

更新日期：2010-12-01 00:00:00

abstract：:Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. Therefore, in addition to virus-specific antibodies, there is considerable interest in immune correlates of protection against these viruses, which could be a target...

journal_title：Journal of virology

authors： Kreijtz JH,de Mutsert G,van Baalen CA,Fouchier RA,Osterhaus AD,Rimmelzwaan GF

更新日期：2008-06-01 00:00:00

abstract：:Butyrate is an abundant metabolite produced by gut microbiota. While butyrate is a known histone deacetylase inhibitor that activates expression of many genes involved in immune system pathways, its effects on virus infections and on the antiviral type I interferon (IFN) response have not been adequately investigated....

journal_title：Journal of virology

authors： Chemudupati M,Kenney AD,Smith AC,Fillinger RJ,Zhang L,Zani A,Liu SL,Anderson MZ,Sharma A,Yount JS

更新日期：2020-07-30 00:00:00

abstract：:In this report, we describe the isolation, molecular genetic mapping, and phenotypic characterization of vaccinia virus mutants resistant to cytosine arabinoside (araC) and phosphonoacetic acid (PAA). At 37 degrees C, 8 microM araC was found to prevent macroscopic plaque formation by wild-type virus and to cause a 10(...

journal_title：Journal of virology

authors： Taddie JA,Traktman P

更新日期：1993-07-01 00:00:00

abstract：:We determined the sequence of the gene for the virion transactivator protein Vmw65 of herpes simplex virus type 2 (HSV-2), strain 333. An analysis of the coding sequence revealed an overall high degree of primary sequence conservation (86%) relative to the HSV-1 protein, although the carboxy-terminal region which enco...

journal_title：Journal of virology

authors： Greaves RF,O'Hare P

更新日期：1991-12-01 00:00:00

abstract：:Defective reovirions lacking the largest (L-1) of the normal 10 genomic segments grow only in association with helper reovirus. Because of the similarity in properties of defective and infectious virions, separation of the two populations by physical methods has been unseccessful. Controlled digestion of purified viru...

journal_title：Journal of virology

authors： Spandidos DA,Graham AF

更新日期：1975-04-01 00:00:00

abstract：:In 1997, an H5N1 influenza virus outbreak occurred in chickens in Hong Kong, and the virus was transmitted directly to humans. Because there is limited information about the avian influenza virus reservoir in that region, we genetically characterized virus strains isolated in Hong Kong during the 1997 outbreak. We seq...

journal_title：Journal of virology

authors： Hoffmann E,Stech J,Leneva I,Krauss S,Scholtissek C,Chin PS,Peiris M,Shortridge KF,Webster RG

更新日期：2000-07-01 00:00:00

abstract：:Apoptosis was postulated as the main barrier to replication of the Autographa californica nuclear polyhedrosis virus (AcMNPV) in a Spodoptera littoralis SL2 cell line (N. Chejanovsky and E. Gershburg, Virology 209:519-525, 1995). Thus, we hypothesized that the viral apoptotic suppressor gene p35 is either poorly expre...

journal_title：Journal of virology

authors： Gershburg E,Rivkin H,Chejanovsky N

更新日期：1997-10-01 00:00:00

abstract：:Infection of Escherichia coli with the satellite virus P4 without its helper bacteriophage P2 leads either to the immune integrated state or to the nonimmune multicopy plasmid condition. We analyzed the transcription pattern of the phage plasmid P4 early and late after infection and during the stable plasmid or lysoge...

journal_title：Journal of virology

authors： Dehó G,Zangrossi S,Ghisotti D,Sironi G

更新日期：1988-05-01 00:00:00

abstract：:Envelope glycoprotein E1 (gp51 to gp54) is the most antigenic protein of hog cholera virus or classical swine fever virus (CSFV). Four antigenic domains, A to D, have been mapped on E1 with a panel of monoclonal antibodies (MAbs) raised against CSFV strain Brescia. The boundaries of these domains have been established...

journal_title：Journal of virology

authors： van Rijn PA,Miedema GK,Wensvoort G,van Gennip HG,Moormann RJ

更新日期：1994-06-01 00:00:00

abstract：:Human cytomegalovirus UL25 codes for a structural phosphoprotein of 85 kDa (C. J. Baldick and T. Shenk, J. Virol. 70:6097-6105, 1996; M. C. Battista et al., J. Virol. 73:3800-3809, 1999). In this study we analyzed the intracellular and intraviral localization of pUL25 by confocal and immunoelectron microscopy and foun...

journal_title：Journal of virology

authors： Zini N,Battista MC,Santi S,Riccio M,Bergamini G,Landini MP,Maraldi NM

更新日期：1999-07-01 00:00:00

abstract：:Coronavirus envelope (E) proteins are small (approximately 75- to 110-amino-acid) membrane proteins that have a short hydrophilic amino terminus, a relatively long hydrophobic membrane domain, and a long hydrophilic carboxy-terminal domain. The protein is a minor virion structural component that plays an important, no...

journal_title：Journal of virology

authors： Ye Y,Hogue BG

更新日期：2007-04-01 00:00:00

abstract：:Glycoprotein B (gB) of herpes simplex virus (HSV) is one of four glycoproteins essential for viral entry and cell fusion. Recently, paired immunoglobulin-like type 2 receptor (PILRalpha) was identified as a receptor for HSV type 1 (HSV-1) gB. Both PILRalpha and a gD receptor were shown to participate in HSV-1 entry in...

journal_title：Journal of virology

authors： Fan Q,Lin E,Satoh T,Arase H,Spear PG

更新日期：2009-08-01 00:00:00