Conserved and exposed epitopes on intact, native, primary human immunodeficiency virus type 1 virions of group M.

abstract：:An E1-E3-deleted recombinant adenovirus vector expressing the hybrid protein TetR-KRAB has been produced. In this virus, AdTG9562, the E2 transcription is regulated by TetR-KRAB and tetO sequences inserted in cis. In the absence of tetracycline, a strong reduction in E2A gene expression, viral DNA replication, and lat...

journal_title：Journal of virology

authors： Rittner K,Schultz H,Pavirani A,Mehtali M

更新日期：1997-04-01 00:00:00

abstract：:We previously observed that when human immunodeficiency virus (HIV)-infected T lymphocytes are added to epithelial cells, they adhere, polarize, and secrete virions unidirectionally onto the epithelium. Epithelial cells subsequently take up virus and become productively infected. We report here that colchicine treatme...

journal_title：Journal of virology

authors： Pearce-Pratt R,Malamud D,Phillips DM

更新日期：1994-05-01 00:00:00

abstract：:The inclusion of Mimiviridae members in the putative monophyletic nucleocytoplasmic large DNA virus (NCLDV) group is based on genomic and phylogenomic patterns. This shows that, along with other viral families, they share a set of genes known as core or "hallmark genes," including the gene for the major capsid protein...

journal_title：Journal of virology

authors： Boratto PVM,Dornas FP,da Silva LCF,Rodrigues RAL,Oliveira GP,Cortines JR,Drumond BP,Abrahão JS

更新日期：2018-01-02 00:00:00

abstract：:The synthesis of viral RNA by wild-type vesicular stomatitis virus (L(1)VSV) and a small, plaque-size mutant (S(2)VSV) was studied in vitro and in chicken embryo (CE) and mouse L-cell cultures. Virus-specific RNA synthesized in CE or L cells infected with either L(1) or S(2)VSV at low multiplicity was of the same size...

journal_title：Journal of virology

authors： Wertz GW,Levine M

更新日期：1973-08-01 00:00:00

abstract：:TR1.3 is a Friend murine leukemia virus (MLV) that induces selective syncytium induction (SI) of brain capillary endothelial cells (BCEC), intracerebral hemorrhage, and death. Syncytium induction by TR1.3 has been mapped to a single tryptophan-to-glycine conversion at position 102 of the envelope glycoprotein (Env102)...

journal_title：Journal of virology

authors： Murphy SL,Chung-Landers M,Honczarenko M,Gaulton GN

更新日期：2006-05-01 00:00:00

abstract：:Feline leukemia virus (FeLV) proviruses have been characterized from naturally occurring non-B-cell, non-T-cell tumors occurring in the spleens of infected cats. These proviruses exhibit a unique sequence motif in the long terminal repeat (LTR), namely, a 21-bp tandem triplication beginning 25 bp downstream of the enh...

journal_title：Journal of virology

authors： Athas GB,Lobelle-Rich P,Levy LS

更新日期：1995-06-01 00:00:00

abstract：:Adenovirus (Ad) gene transfer vectors can be used to transfer and express antigens and function as strong adjuvants and thus are useful platforms for the development of genetic vaccines. Based on the hypothesis that Ad vectors with enhanced infectibility of dendritic cells (DC) may be able to evoke enhanced immune res...

journal_title：Journal of virology

authors： Worgall S,Busch A,Rivara M,Bonnyay D,Leopold PL,Merritt R,Hackett NR,Rovelink PW,Bruder JT,Wickham TJ,Kovesdi I,Crystal RG

更新日期：2004-03-01 00:00:00

abstract：:Half of the world's population is exposed to the risk of dengue virus infection. Although a vaccine for dengue virus is now available in a few countries, its reported overall efficacy of about 60% is not ideal. Protective immune correlates following natural dengue virus infection remain undefined, which makes it diffi...

journal_title：Journal of virology

authors： Xu M,Züst R,Toh YX,Pfaff JM,Kahle KM,Davidson E,Doranz BJ,Velumani S,Tukijan F,Wang CI,Fink K

更新日期：2016-11-28 00:00:00

abstract：:Herpes simplex virus (HSV) codes for several envelope glycoproteins, including glycoprotein G-2 (gG-2) of HSV type 2 (HSV-2), which are dispensable for replication in cell culture. However, clinical isolates which are deficient in such proteins occur rarely. We describe here five clinical HSV-2 isolates which were fou...

journal_title：Journal of virology

authors： Liljeqvist JA,Svennerholm B,Bergström T

更新日期：1999-12-01 00:00:00

abstract：:Antiviral effects were characterized for two oligodeoxyribonucleoside methylphosphonates synthesized in an antisense (3'-TCTTAACC-5') or a sense (5'-AGAATTGG-3') orientation, based on the RNA sequence of the first splice acceptor site of the tat-3 gene of human immunodeficiency virus (HIV) (5'...AGAAUUGG...3'). The de...

journal_title：Journal of virology

authors： Zaia JA,Rossi JJ,Murakawa GJ,Spallone PA,Stephens DA,Kaplan BE,Eritja R,Wallace RB,Cantin EM

更新日期：1988-10-01 00:00:00

abstract：:The immune response to a synthetic peptide, H3 HA1(305-328), representing the C'-terminal 24 amino acid residues of the HA1 chain of the hemagglutinin of the H3 subtype of influenza virus is controlled by genes in the I region of the major histocompatibility complex. Mice of the H-2d haplotype are high responders and ...

journal_title：Journal of virology

authors： Brown LE,Murray JM,Anders EM,Tang XL,White DO,Tregear GW,Jackson DC

更新日期：1988-05-01 00:00:00

abstract：:Most retroviral packaging cell lines were established by a helper virus plasmid cotransfected with a separate plasmid encoding a selection marker. Since this selection marker coexisted in trans with the helper virus sequence, helper virus gene expression could be inactivated by host DNA methylation despite selection f...

journal_title：Journal of virology

authors： Young WB,Link CJ Jr

更新日期：2000-06-01 00:00:00

abstract：:The DNA sequence of 3,240 nucleotides of the XbaI G fragment located in the unique long (UL) region of the equine herpesvirus 1 genome revealed two major open reading frames (ORFs) designated UL3 and UL4. The UL3 ORF of 470 amino acids (aa) maps at nucleotides (nt) 4450 to 3038 from the long terminus, and its predicte...

journal_title：Journal of virology

authors： Zhao Y,Holden VR,Harty RN,O'Callaghan DJ

更新日期：1992-09-01 00:00:00

abstract：:The immune response to bovine herpesvirus 1 (BHV-1) infection can protect cattle from subsequent challenge with the virus. This protection involves a variety of defensive strategies, and the activation of most of these defenses requires the recognition of viral proteins by the cellular immune system. To identify some ...

journal_title：Journal of virology

authors： Hutchings DL,van Drunen Littel-van den Hurk S,Babiuk LA

更新日期：1990-10-01 00:00:00

abstract：:Long interspersed nuclear element 1 (LINE-1; L1) retrotransposons are the most common retroelements in mammalian genomes. Unlike individual families of endogenous retroviruses (ERVs), they have remained active throughout the mammalian radiation and are responsible for most of the retroelement movement and much genome ...

journal_title：Journal of virology

authors： Erickson IK,Cantrell MA,Scott L,Wichman HA

更新日期：2011-12-01 00:00:00

abstract：:Cottontail rabbit papillomavirus (CRPV)-induced papillomas progress at a high frequency to carcinomas and thus can serve as a model for high-cancer-risk human papillomavirus infection. Previously, we have shown that antibodies to nonstructural and structural proteins are detected in only a fraction of papilloma-bearin...

journal_title：Journal of virology

authors： Selvakumar R,Borenstein LA,Lin YL,Ahmed R,Wettstein FO

更新日期：1994-06-01 00:00:00

abstract：:Recombinant poxvirus vectors are undergoing intensive evaluation as vaccine candidates for a variety of infectious pathogens. Avipoxviruses, such as canarypox virus, are replication deficient in mammalian cells by virtue of a poorly understood species-specific restriction. Highly attenuated vaccinia virus strains such...

journal_title：Journal of virology

authors： Zhang X,Cassis-Ghavami F,Eller M,Currier J,Slike BM,Chen X,Tartaglia J,Marovich M,Spearman P

更新日期：2007-07-01 00:00:00

abstract：:Nine virulent bacteriophages of the anaerobe Corynebacterium (Propionibacterium) acnes, the P-a series, are DNA phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. They have isometric heads (420 by 460 nm), and are placed in Bradley's group B-1. There is permanent plaque suppression a...

journal_title：Journal of virology

authors： Zierdt CH

更新日期：1974-11-01 00:00:00

abstract：:We have identified a cytomegalovirus virion protein capable of modulating the rapid induction of an interferon-like response in cells that follows virus binding and penetration. Functional genomics revealed a role for the major cytomegalovirus structural protein, pp65 (ppUL83), in counteracting this response. The unde...

journal_title：Journal of virology

authors： Abate DA,Watanabe S,Mocarski ES

更新日期：2004-10-01 00:00:00

abstract：:The sequence of the human immunodeficiency virus type 2 circle junction was determined. The most common sequence found between the conserved CA and TG dinucleotides at the ends of the integrated provirus was five bases long (GGTAC). This suggests that the integration of human immunodeficiency virus type 2 DNA is accom...

journal_title：Journal of virology

authors： Whitcomb JM,Hughes SH

更新日期：1991-07-01 00:00:00

abstract：:Several domains of CD4 have been suggested to play a critical role in events that follow its binding to the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41). It has been reported previously that cells expressing a chimeric molecule consisting of the first 177 residues of human CD4 attache...

journal_title：Journal of virology

authors： Golding H,Blumenthal R,Manischewitz J,Littman DR,Dimitrov DS

更新日期：1993-11-01 00:00:00

abstract：:Expression of several major histocompatibility complex (MHC) class I alleles is associated with a protective effect against disease progression in both human immunodeficiency virus type 1 and simian immunodeficiency virus infection. To understand the mechanism underlying this effect, we investigated the expression of ...

journal_title：Journal of virology

authors： Zhang ZQ,Fu TM,Casimiro DR,Davies ME,Liang X,Schleif WA,Handt L,Tussey L,Chen M,Tang A,Wilson KA,Trigona WL,Freed DC,Tan CY,Horton M,Emini EA,Shiver JW

更新日期：2002-12-01 00:00:00

abstract：:Marburg virus (MARV) has been associated with sporadic episodes of hemorrhagic fever, including a recent highly publicized outbreak in Angola that produced severe disease and significant mortality in infected patients. MARV is also considered to have potential as a biological weapon. Recently, we reported the developm...

journal_title：Journal of virology

authors： Daddario-DiCaprio KM,Geisbert TW,Geisbert JB,Ströher U,Hensley LE,Grolla A,Fritz EA,Feldmann F,Feldmann H,Jones SM

更新日期：2006-10-01 00:00:00

abstract：:Previous work demonstrated that a herpes simplex virus type 1 (HSV-1) immediate-early function up-regulates beta interferon but not chloramphenicol acetyltransferase reporter genes driven by the strong simian virus 40 (SV40) or cytomegalovirus promoter-enhancer regions in both transient assays and stable cell lines. T...

journal_title：Journal of virology

authors： Brown CR,Nakamura MS,Mosca JD,Hayward GS,Straus SE,Perera LP

更新日期：1995-11-01 00:00:00

abstract：:The hepatitis B virus (HBV) X protein (HBx) is a multifunctional regulator of cellular signal transduction and transcription pathways and has a critical role in HBV replication. Much of the cytoplasmic signal transduction activity associated with HBx expression and its stimulation of viral replication is attributable ...

journal_title：Journal of virology

authors： Bouchard MJ,Wang L,Schneider RJ

更新日期：2006-05-01 00:00:00

abstract：:At least four members of the integrin family of receptors, alphaVbeta1, alphaVbeta3, alphaVbeta6, and alphaVbeta8, have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro. Our investigators have recently shown that the efficiency of receptor usage appears to be related to the viral serotype ...

journal_title：Journal of virology

authors： Duque H,LaRocco M,Golde WT,Baxt B

更新日期：2004-09-01 00:00:00

abstract：:The genome RNA and six mRNA species of infectious hematopoietic necrosis virus were analyzed by denaturing gel electrophoresis. The following molecular weights were determined: genome RNA, 3.7 X 10(6); mRNA 1, 2.26 X 10(6); mRNA 2, 5.63 X 10(5); mRNA 3, 4.84 X 10(5); mRNA 4 (containing two different mRNA species), 3.0...

journal_title：Journal of virology

authors： Kurath G,Leong JC

更新日期：1985-02-01 00:00:00

abstract：:The internal structural proteins of retroviruses are proteolytically processed from the Gag polyprotein, which alone is able to assemble into virus-like particles when expressed in cells. All Gag proteins contain domains corresponding to the three structural proteins MA, CA, and NC. We have expressed the CA and NC dom...

journal_title：Journal of virology

authors： Campbell S,Vogt VM

更新日期：1995-10-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of the aggressive and fatal disease adult T-cell leukemia. Previous studies have demonstrated that the HTLV-1-encoded Tax protein inhibits the function of tumor suppressor p53 through a Tax-induced NF-kappaB pathway. Given these attributes, we were int...

journal_title：Journal of virology

authors： Jung KJ,Dasgupta A,Huang K,Jeong SJ,Pise-Masison C,Gurova KV,Brady JN

更新日期：2008-09-01 00:00:00

abstract：:RNA from adenovirus 2-infected KB cells was annealed in liquid with RNA in vast excess to viral heavy (l) and light (r) 32P-labeled DNA strands. Hybridization kinetics were analyzed by computer to estimate the number of viral RNA abundance classes, their relative concentrations, and the fraction of each DNA strand fro...

journal_title：Journal of virology

authors： Wold WS,Green M,Brackmann KH,Cartas MA,Devine C

更新日期：1976-11-01 00:00:00