Properties of Corynebacterium acnes bacteriophage and description of an interference phenomenon.

Abstract:

:Nine virulent bacteriophages of the anaerobe Corynebacterium (Propionibacterium) acnes, the P-a series, are DNA phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. They have isometric heads (420 by 460 nm), and are placed in Bradley's group B-1. There is permanent plaque suppression at highest phage concentrations. After 100- to 1,000-fold dilution, plaques are evident. The latent period is 1 h and burst size 25. Cross-neutralization data of antisera for the nine phages are similar. There is an unexplained precipitous drop in plaque-forming units during the first 5 min of neutralization, after which the rate is linear for 2 h. They are sensitive to pH extremes but are partially protected even at pH 4 or 9 by storage at 4 C. They are resistant to ether and chloroform and are inactivated within 10 min at 70 C.

journal_name

J Virol

journal_title

Journal of virology

authors

Zierdt CH

doi

10.1128/JVI.14.5.1268-1273.1974

subject

Has Abstract

pub_date

1974-11-01 00:00:00

pages

1268-7

issue

5

eissn

0022-538X

issn

1098-5514

journal_volume

14

pub_type

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