Abstract:
:The binding of a recombinant soluble form of the measles virus (MV) hemagglutinin (sH) to cells expressing hybrid CD46/CD4 proteins was compared to that of purified virus. For binding of both ligands, both CD46 external short consensus repeats I and II (SCR I and II) in the natural order were essential. The addition of SCR III and IV enhanced virus binding but inhibited sH binding. Accordingly, this lowered the ability of sH to compete with MV binding. Antihemagglutinin monoclonal antibodies selectively inhibited the binding of either sH or MV. Thus, sH and MV share a common binding site in SCR I and II but differ in their apparent avidity to CD46 under the influence of SCR III and IV.
journal_name
J Viroljournal_title
Journal of virologyauthors
Devaux P,Buchholz CJ,Schneider U,Escoffier C,Cattaneo R,Gerlier Ddoi
10.1128/JVI.71.5.4157-4160.1997subject
Has Abstractpub_date
1997-05-01 00:00:00pages
4157-60issue
5eissn
0022-538Xissn
1098-5514journal_volume
71pub_type
杂志文章abstract::Poliovirus infection of HeLa cells results in a rapid inhibition of host protein synthesis by a mechanism that does not affect the translation of poliovirus RNA. It has been suggested that this virus-induced translational control results from inactivation of the cap-binding protein complex, and it has been shown that ...
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pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.68.10.6523-6534.1994
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journal_title:Journal of virology
pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00996-19
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.78.6.2701-2710.2004
更新日期:2004-03-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2015-04-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02367-07
更新日期:2008-05-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.77.8.4836-4847.2003
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.79.7.4506-4509.2005
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.75.20.9679-9686.2001
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journal_title:Journal of virology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2002-02-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2015-01-15 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.73.5.3682-3691.1999
更新日期:1999-05-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.35.1.219-232.1980
更新日期:1980-07-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2010-05-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.06556-11
更新日期:2012-03-01 00:00:00
abstract::Genetic and biochemical studies have suggested the existence of a bacteriophage-like, DNA-packaging/ejecting portal complex in herpesviruses capsids, but its arrangement remained unknown. Here, we report the first visualization of a unique vertex in the Kaposi's sarcoma-associated herpesvirus (KSHV) capsid by cryoelec...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02254-06
更新日期:2007-04-01 00:00:00