Interaction of West Nile virus with primary murine macrophages: role of cell activation and receptors for antibody and complement.

abstract：:Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene in a Moloney murine leukemia virus-based vector results in the generation of 10- to 40-fold higher titers of virus. ...

journal_title：Journal of virology

authors： Armentano D,Yu SF,Kantoff PW,von Ruden T,Anderson WF,Gilboa E

更新日期：1987-05-01 00:00:00

abstract：:Hemagglutination (HA) by the mammalian reoviruses is mediated by interactions between the viral sigma 1 protein and sialoglycoproteins on the erythrocyte surface. Three serotype 3 (T3) reovirus strains were identified that do not agglutinate either bovine or type O human erythrocytes (HA negative): T3 clone 43 (T3C43)...

journal_title：Journal of virology

authors： Dermody TS,Nibert ML,Bassel-Duby R,Fields BN

更新日期：1990-10-01 00:00:00

abstract：UNLABELLED:Hepatitis C virus (HCV) requires proteins from the NS3-NS5B polyprotein to create a replicase unit for replication of its genome. The replicase proteins form membranous compartments in cells to facilitate replication, but little is known about their functional organization within these structures. We recentl...

journal_title：Journal of virology

authors： Gomes RG,Isken O,Tautz N,McLauchlan J,McCormick CJ

更新日期：2015-12-30 00:00:00

abstract：UNLABELLED:Antibodies against the fusion (F) protein of respiratory syncytial virus (RSV) play an important role in the protective immune response to this important respiratory virus. Little is known, however, about antibody levels against multiple F-specific epitopes induced by infection or after vaccination against R...

journal_title：Journal of virology

authors： Widjaja I,Wicht O,Luytjes W,Leenhouts K,Rottier PJM,van Kuppeveld FJM,Haijema BJ,de Haan CAM

更新日期：2016-06-10 00:00:00

abstract：:CM2 is the second membrane protein of the influenza C virus and has been demonstrated to play a role in the uncoating and genome packaging processes in influenza C virus replication. Although the effects of N-linked glycosylation, disulfide-linked oligomerization, and palmitoylation of CM2 on virus replication have be...

journal_title：Journal of virology

authors： Goto T,Shimotai Y,Matsuzaki Y,Muraki Y,Sho R,Sugawara K,Hongo S

更新日期：2017-10-27 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) infects >90% of the population and establishes a latent infection with asymptomatic episodes of reactivation. However, HHV-6 reactivation is associated with morbidity and sometimes mortality in immunocompromised patients. To date, control of the virus in healthy virus carriers and the failu...

journal_title：Journal of virology

authors： Fastenackels S,Bayard C,Larsen M,Magnier P,Bonnafous P,Seddiki N,Appay V,Gautheret-Dejean A,Sauce D

更新日期：2019-06-14 00:00:00

abstract：:Information was sought on the temporal distribution of transmissible mink encephalopathy virus in royal pastel mink inoculated subcutaneously with 10(3.0) 50% intracerebral lethal doses of the Idaho strain. As determined by intracerebral assay in mink, extremely little replication of the virus occurred during the prec...

journal_title：Journal of virology

authors： Hadlow WJ,Race RE,Kennedy RC

更新日期：1987-10-01 00:00:00

abstract：:Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in pigs. Furthermore, the evolutionary dynamics of influenza virus in pigs have ...

journal_title：Journal of virology

authors： Wei K,Sun H,Sun Z,Sun Y,Kong W,Pu J,Ma G,Yin Y,Yang H,Guo X,Chang KC,Liu J

更新日期：2014-10-01 00:00:00

abstract：:A detailed comparison of the gp70 proteins of cloned ecotropic Friend murine leukemia virus (FLV) and dual-tropic Friend mink focus-forming virus (FrMCF) was performed by analyzing the structural and immunological properties of amino- and carboxy-terminal domains of these molecules generated upon controlled trypsiniza...

journal_title：Journal of virology

authors： Pinter A,Honnen WJ

更新日期：1984-02-01 00:00:00

abstract：:The activity and epithelial tropism of the human papillomavirus type 18 P105 early promoter, which directs the synthesis of the E6 and E7 transforming genes, are controlled by cis elements included in the viral long control region. To identify potential cellular regulators of this promoter, we mutagenized one or both ...

journal_title：Journal of virology

authors： Thierry F,Spyrou G,Yaniv M,Howley P

更新日期：1992-06-01 00:00:00

abstract：:High-risk human papillomaviruses (HPVs), including HPV-16 and HPV-18, are the causative agents of cervical carcinomas and are linked to several other tumors of the anogenital and oropharyngeal regions. The majority of HPV-induced tumors contain integrated copies of the normally episomal HPV genome that invariably reta...

journal_title：Journal of virology

authors： Kennedy EM,Kornepati AV,Goldstein M,Bogerd HP,Poling BC,Whisnant AW,Kastan MB,Cullen BR

更新日期：2014-10-01 00:00:00

abstract：:Mlvi-1 defines a locus of proviral integration in rat thymomas induced by Moloney murine leukemia virus. pvt-1/Mis-1 represents an independently identified locus which becomes rearranged either by chromosomal translocation in murine plasmacytomas or by provirus insertion in retrovirus-induced murine and rat thymic lym...

journal_title：Journal of virology

authors： Koehne CF,Lazo PA,Alves K,Lee JS,Tsichlis PN,O'Donnell PV

更新日期：1989-05-01 00:00:00

abstract：:With the aid of three monoclonal antibodies (MAbs), a glycoprotein specifically localized to the outer envelope of vaccinia virus was shown to be encoded by the A33R gene. These MAbs reacted with a glycosylated protein that migrated as 23- to 28-kDa and 55-kDa species under reducing and nonreducing conditions, respect...

journal_title：Journal of virology

authors： Roper RL,Payne LG,Moss B

更新日期：1996-06-01 00:00:00

abstract：:Vaccinia virus, the basis of the smallpox vaccine, is one of the largest viruses to replicate in humans. We have used in situ atomic force microscopy (AFM) to directly visualize fully hydrated, intact intracellular mature vaccinia virus (IMV) virions and chemical and enzymatic treatment products thereof. The latter in...

journal_title：Journal of virology

authors： Malkin AJ,McPherson A,Gershon PD

更新日期：2003-06-01 00:00:00

abstract：:Two of 25 healthy pet sooty mangabey (SM) monkeys (Cercocebus atys) living in West Africa were seropositive by immunoblot when surveyed for antibody to simian immunodeficiency virus of macaques (SIVmac). SIVsmLIB1 was isolated from one of the pet sooty mangabeys. Nucleotide sequence data showed that this isolate is a ...

journal_title：Journal of virology

authors： Marx PA,Li Y,Lerche NW,Sutjipto S,Gettie A,Yee JA,Brotman BH,Prince AM,Hanson A,Webster RG

更新日期：1991-08-01 00:00:00

abstract：:The N-terminal domain of the bovine papillomavirus type 1 E2 protein is important for viral DNA replication, for transcriptional transactivation, and for interaction with the E1 protein. To determine which residues of this 200-amino-acid domain are important for these activities, single conservative amino acid substit...

journal_title：Journal of virology

authors： Brokaw JL,Blanco M,McBride AA

更新日期：1996-01-01 00:00:00

abstract：:The product of the human cytomegalovirus (HCMV) UL71 gene is conserved throughout the herpesvirus family. During HCMV infection, protein pUL71 is required for efficient virion egress and is involved in the final steps of secondary envelopment leading to infectious viral particles. We found strong indications for oligo...

journal_title：Journal of virology

authors： Meissner CS,Suffner S,Schauflinger M,von Einem J,Bogner E

更新日期：2012-03-01 00:00:00

abstract：:Oncostatin M (OSM) is released together with type I interferon (IFN) by activated dendritic cells, suggesting a concerted action of these cytokines in the biological response against infection. We found that OSM increases the antiviral effect of IFN-alpha in Huh7 hepatoma cells infected with hepatitis A or hepatitis C...

journal_title：Journal of virology

authors： Larrea E,Aldabe R,Gonzalez I,Segura V,Sarobe P,Echeverria I,Prieto J

更新日期：2009-04-01 00:00:00

abstract：:The activity of phosphatidylinositol 4-kinase class III beta (PI4KIIIβ) has been shown to be required for the replication of multiple picornaviruses; however, it is unclear whether a physical association between PI4KIIIβ and the viral replication machinery exists and, if it does, whether association is necessary. We e...

journal_title：Journal of virology

authors： Greninger AL,Knudsen GM,Betegon M,Burlingame AL,Derisi JL

更新日期：2012-04-01 00:00:00

abstract：:Rabies, caused by rabies virus (RABV), is a fatal encephalitis in humans and other mammals, which continues to present a public health threat in most parts of the world. Our previous study demonstrated that Toll-like receptor 7 (TLR7) is essential in the induction of anti-RABV antibodies via the facilitation of germin...

journal_title：Journal of virology

authors： Luo Z,Lv L,Li Y,Sui B,Wu Q,Zhang Y,Pei J,Li M,Zhou M,Hooper DC,Fu ZF,Zhao L

更新日期：2020-04-16 00:00:00

abstract：:The phenomenon of prion strains with distinct biological characteristics has been hypothesized to be involved in the structural diversity of abnormal prion protein (PrP(Sc)). However, the molecular basis of the transmission of strain properties remains poorly understood. Real-time quaking-induced conversion (RT-QUIC) ...

journal_title：Journal of virology

authors： Sano K,Atarashi R,Ishibashi D,Nakagaki T,Satoh K,Nishida N

更新日期：2014-10-01 00:00:00

abstract：:Helicobacter pylori causes peptic ulcers and gastric cancer, which lead to significantly higher morbidity in Japan than elsewhere in the world. As bacteriophage (phage) and host bacteria coevolve, the study of H. pylori phages is important to extend understanding of the evolution and pathogenesis of H. pylori. Here we...

journal_title：Journal of virology

authors： Uchiyama J,Takeuchi H,Kato S,Takemura-Uchiyama I,Ujihara T,Daibata M,Matsuzaki S

更新日期：2012-10-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) mutations that confer escape from cytotoxic T-lymphocyte (CTL) recognition can sometimes result in lower viral fitness. These mutations can then revert upon transmission to a new host in the absence of CTL-mediated immune selection pressure restricted by the HLA alleles of t...

journal_title：Journal of virology

authors： Rousseau CM,Daniels MG,Carlson JM,Kadie C,Crawford H,Prendergast A,Matthews P,Payne R,Rolland M,Raugi DN,Maust BS,Learn GH,Nickle DC,Coovadia H,Ndung'u T,Frahm N,Brander C,Walker BD,Goulder PJ,Bhattacharya T,Hecke

更新日期：2008-07-01 00:00:00

abstract：UNLABELLED:The APOBEC3 family of DNA cytosine deaminases has important roles in innate immunity and cancer. It is unclear how DNA tumor viruses regulate these enzymes and how these interactions, in turn, impact the integrity of both the viral and cellular genomes. Polyomavirus (PyVs) are small DNA pathogens that contai...

journal_title：Journal of virology

authors： Verhalen B,Starrett GJ,Harris RS,Jiang M

更新日期：2016-06-24 00:00:00

abstract：:Papillomaviruses normally replicate in stratified squamous epithelial tissues of their mammalian hosts, in which the viral genome is found as a nuclear plasmid. Two viral proteins, E1, a helicase, and E2, a transcriptional activator and plasmid maintenance factor, are known to contribute to the episomal replication of...

journal_title：Journal of virology

authors： Angeletti PC,Kim K,Fernandes FJ,Lambert PF

更新日期：2002-04-01 00:00:00

abstract：:In adenovirus-infected cells, the epidermal growth factor receptor (EGF-R) is internalized from the cell surface via endosomes and is degraded, and the E3 10,400-dalton protein (10.4K protein) is required for this effect (C. R. Carlin, A. E. Tollefson, H. A. Brady, B. L. Hoffman, and W. S. M. Wold, Cell 57:135-144, 19...

journal_title：Journal of virology

authors： Tollefson AE,Stewart AR,Yei SP,Saha SK,Wold WS

更新日期：1991-06-01 00:00:00

abstract：:Mature nonstructural protein-15 (nsp15) from the severe acute respiratory syndrome coronavirus (SARS-CoV) contains a novel uridylate-specific Mn2+-dependent endoribonuclease (NendoU). Structure studies of the full-length form of the obligate hexameric enzyme from two CoVs, SARS-CoV and murine hepatitis virus, and its ...

journal_title：Journal of virology

authors： Joseph JS,Saikatendu KS,Subramanian V,Neuman BW,Buchmeier MJ,Stevens RC,Kuhn P

更新日期：2007-06-01 00:00:00

abstract：:Two forms of herpes simplex virus glycoprotein gD were recombined into Autographa californica nuclear polyhedrosis virus (baculovirus) and expressed in infected Spodoptera frugiperda (Sf9) cells. Each protein was truncated at residue 306 of mature gD. One form, gD-1(306t), contains the coding sequence of Patton strain...

journal_title：Journal of virology

authors： Sisk WP,Bradley JD,Leipold RJ,Stoltzfus AM,Ponce de Leon M,Hilf M,Peng C,Cohen GH,Eisenberg RJ

更新日期：1994-02-01 00:00:00

abstract：:We have previously described the expression of the major nonstructural protein (NS-1) of Aleutian mink disease parvovirus (ADV) in insect cells by using a baculovirus vector (J. Christensen, T. Storgaard, B. Bloch, S. Alexandersen, and B. Aasted, J. Virol. 67:229-238, 1993). To study its biochemical properties, ADV NS...

journal_title：Journal of virology

authors： Christensen J,Pedersen M,Aasted B,Alexandersen S

更新日期：1995-03-01 00:00:00

abstract：:Feline calicivirus is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of Caliciviridae. We have examined the entry process of feline calicivirus (FCV). An earlier study demonstrated that acidification in endosomes may be required. We have confirmed this observatio...

journal_title：Journal of virology

authors： Stuart AD,Brown TD

更新日期：2006-08-01 00:00:00