Abstract:
:The effects of GABA antagonists, picrotoxin and bicuculline were studied on hyperphagia caused by insulin in free feeding rats. It was found that peripheral administration of GABA antagonists inhibited this hyperphagia. These agents were administered in the VMH and LH through stereotaxically implanted cannulae. It was found that the food intake was inhibited when injected into the VMH, but not in the LH. These findings suggest that LH plays a relatively passive role as compared to VMH, where GABA appears to be an important neurotransmitter.
journal_name
Life Scijournal_title
Life sciencesauthors
Kamatchi GL,Bhakthavatsalam P,Chandra D,Bapna JSdoi
10.1016/0024-3205(84)90220-0subject
Has Abstractpub_date
1984-06-04 00:00:00pages
2297-301issue
23eissn
0024-3205issn
1879-0631pii
0024-3205(84)90220-0journal_volume
34pub_type
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