Abstract：
:Addition of LETS glycoprotein to normal or transformed cells produces increased migration of the cells, as determined by formation of phagokinetic tracks on gold particle-coated coverslips. These tracks arise by a combination of phagocytosis of the gold particles and cellular migration. Increased motility is also evident on plastic in the absence of gold particles. The added LETS protein attaches to the cells in a fibrillar network, and binding is greater to normal than to transformed cells. The effects of LETS protein on migration are consistent with its effects on cell adhesion, morphology and cytoskeleton, and have potential implications for the determination of cellular migration in vivo.
journal_name
Celljournal_title
Cellauthors
Ali IU,Hynes ROdoi
10.1016/0092-8674(78)90129-0subject
Has Abstractpub_date
1978-06-01 00:00:00pages
439-46issue
2eissn
0092-8674issn
1097-4172pii
0092-8674(78)90129-0journal_volume
14pub_type
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