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Protein synthesis in Rift Valley fever virus-infected cells.

Abstract：

:Rift Valley fever virus-induced protein synthesis was examined by polyacrylamide gel electrophoresis and fluorography. Five virus-induced polypeptides were detected, the nucleocapsid protein N, the nucleus-associated nonstructural protein NS1, the glycoproteins G1 and G2, and a protein of molecular weight 80K. The N, G1, G2, and 80K proteins were present in virion preparations. Sequential studies showed that NS1 accumulated in the nucleus as soon as it was formed and readily associated with nuclei partitioned from noninfected cells. The G1 and G2 proteins labelled with [3H]glucosamine and [3H]mannose. NS1 was shown to be the only virus-induced protein which was phosphorylated.

journal_name

Virology

journal_title

Virology

authors

Struthers JK,Swanepoel R,Shepherd SP

doi

10.1016/0042-6822(84)90277-0

subject

Has Abstract

pub_date

1984-04-15 00:00:00

pages

118-24

issue

1

eissn

0042-6822

issn

1096-0341

pii

0042-6822(84)90277-0

journal_volume

134

pub_type

杂志文章

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