Zoonotic potential of highly pathogenic avian H7N3 influenza viruses from Pakistan.

abstract：:Virions of southern bean mosaic virus (SBMV) show two distinct sensitivity patterns upon heating. Infectivity loss and capsid denaturation occur concurrently if virions are exposed at 50-55 degrees in 0.1 M sodium phosphate buffer, pH 7.5, or 0.1 M glycine-phosphate buffer, pH 9.0. Contrastingly, virions are inactivat...

journal_title：Virology

authors： Veerisetty V,El-Hassan SA,Sehgal OP

更新日期：1981-01-30 00:00:00

abstract：:Geminiviruses are small, ssDNA-containing plant viruses. Bean golden mosaic virus (BGMV) and tomato golden mosaic virus (TGMV) have bipartite genomes, the components of which are designated A and B. Although they are closely related, BGMV and TGMV nevertheless exhibit distinct host-specific phenotypes, with BGMV being...

journal_title：Virology

authors： Gillette WK,Meade TJ,Jeffrey JL,Petty IT

更新日期：1998-11-25 00:00:00

abstract：:Latent membrane protein 2A (LMP2A) is expressed in latent Epstein-Barr virus (EBV) infection. LMP2A functions to downregulate B-cell signal transduction and viral reactivation from latency in EBV-immortalized B cells in vitro, and acts to provide B cells with both a survival and developmental signal in vivo. Identific...

journal_title：Virology

authors： Ikeda M,Ikeda A,Longan LC,Longnecker R

更新日期：2000-03-01 00:00:00

abstract：:The baculovirus-insect cell system is used routinely for foreign glycoprotein production, but the precise nature of the N-glycosylation pathway in this system remains unclear. Some studies indicate that these cells cannot process N-linked oligosaccharides to complex forms containing outer-chain galactose and sialic ac...

journal_title：Virology

authors： Jarvis DL,Finn EE

更新日期：1995-10-01 00:00:00

abstract：:Rice tungro disease is caused by a complex of two viruses, Rice tungro bacilliform virus (RTBV) and Rice tungro spherical virus (RTSV). To examine the RNAi-based defence response in rice during tungro disease, we characterized the virus-derived small RNAs and miRNAs by Deep Sequencing. We found that, while 21 nt/22 nt...

journal_title：Virology

authors： Zarreen F,Kumar G,Johnson AMA,Dasgupta I

更新日期：2018-10-01 00:00:00

abstract：:Among 167 rotavirus specimens collected from young children in a suburban area of Bissau, Guinea-Bissau, from 1996 to 1998, most identifiable strains belonged to the uncommon P[6], G2 type and approximately 50% remained incompletely typed. In the present study, 76 such strains were further characterized. Due to interp...

journal_title：Virology

authors： Fischer TK,Page NA,Griffin DD,Eugen-Olsen J,Pedersen AG,Valentiner-Branth P,Mølbak K,Sommerfelt H,Nielsen NM

更新日期：2003-06-20 00:00:00

abstract：:The papillomavirus (PV) E2 protein activates transcription and replication by recruiting cellular proteins and the E1 DNA helicase to their binding sites in the viral genome. We recently demonstrated that phosphorylation of tyrosine 102 in the bovine papillomavirus (BPV-1) E2 protein restricts these activities and tha...

journal_title：Virology

authors： DeSmet M,Kanginakudru S,Jose L,Xie F,Gilson T,Androphy EJ

更新日期：2018-08-01 00:00:00

abstract：:During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) protein, a class I viral fusion protein that has several unique features. Coronavirus entry is unusual in that it is often biphas...

journal_title：Virology

authors： Millet JK,Whittaker GR

更新日期：2018-04-01 00:00:00

abstract：:A chloroplast-localized papaya methionine sulfoxide reductase B1 (PaMsrB1) interacting with Papaya ringspot virus (PRSV) NIa-Pro was identified using a Sos recruitment two-hybrid system (SRS). SRS analysis of several deletion mutants of PRSV NIa-Pro and PaMsrB1 demonstrated that the C-terminal (residues 133-239) fragm...

journal_title：Virology

authors： Gao L,Shen W,Yan P,Tuo D,Li X,Zhou P

更新日期：2012-12-05 00:00:00

abstract：:Ten human genital invasive squamous cell carcinomas and five human premalignant tissues were analyzed for the presence of selected sets of herpes simplex virus 2 (HSV-2) DNA sequences. Two vulvar tumors and one vulvar dysplastic tissue were found to contain DNA sequences homologous to the BglII O fragment (coordinates...

journal_title：Virology

authors： Manservigi R,Cassai E,Deiss LP,Di Luca D,Segala V,Frenkel N

更新日期：1986-11-01 00:00:00

abstract：:The guinea pig cytomegalovirus (GPCMV) co-linear gene and potential functional homolog of HCMV UL84 (GP84) was investigated. The GP84 gene had delayed early transcription kinetics and transient expression studies of GP84 protein (pGP84) demonstrated that it targeted the nucleus and co-localized with the viral DNA poly...

journal_title：Virology

authors： McGregor A,Choi KY,Schleiss MR

更新日期：2011-02-05 00:00:00

abstract：:Recent interest focused on the dynamics of HIV-1 replication in primary monocytes/macrophages and T-lymphocytes of the immune system, as well as the standardization of virological and immunological in vitro assays with primary isolates, provided the impetus for these studies. These types of studies have never been per...

journal_title：Virology

authors： Tsai WP,Conley SR,Kung HF,Garrity RR,Nara PL

更新日期：1996-12-15 00:00:00

abstract：:In addition to its role in virus assembly, the matrix (M) protein of vesicular stomatitis virus (VSV) is involved in virus-induced cell rounding and inhibition of host-directed gene expression. Previous experiments have shown that two M protein mutants genetically dissociate the ability of M protein to inhibit host-di...

journal_title：Virology

authors： Lyles DS,McKenzie MO

更新日期：1997-03-03 00:00:00

abstract：:Genetic recombination resulting in the production of wild-type infectious virus is an obstacle in the current system for producing densovirus transducing particles. In order to eliminate this problem, a double subgenomic Sindbis virus (TE/3'2J/VP) was engineered that expresses the structural proteins (VPs) of Aedes de...

journal_title：Virology

authors： Allen-Miura TM,Afanasiev BN,Olson KE,Beaty BJ,Carlson JO

更新日期：1999-04-25 00:00:00

abstract：:Porcine circovirus type 2 (PCV2) is the causative agent of an emerging swine disease, postweaning multisystemic wasting syndrome. In this work, the RNAs of PCV2 synthesized during productive infection in porcine kidney cells were characterized. A total of nine RNAs were detected. They include the viral capsid protein ...

journal_title：Virology

authors： Cheung AK

更新日期：2003-01-05 00:00:00

abstract：:Turnip crinkle carmovirus (TCV) has a uniquely high recombination frequency and nonrandom cross-over site distribution among the recombining TCV-associated satellite RNAs. An in vitro system has been developed that includes a partially purified TCV replicase preparation (RdRp) and chimeric RNAs that resemble the putat...

journal_title：Virology

authors： Nagy PD,Simon AE

更新日期：1998-09-30 00:00:00

abstract：:Equine herpesvirus 1 (EHV-1) recombinants that carry either a deletion of glycoprotein M (gM) or express mutant forms of gM were constructed. The recombinants were derived from strain Kentucky A (KyA), which also lacks genes encoding gE and gI. Plaques on RK13 cells induced by the gM-negative KyA were reduced in size ...

journal_title：Virology

authors： Seyboldt C,Granzow H,Osterrieder N

更新日期：2000-12-20 00:00:00

abstract：:Fiber and penton base overproduced in adenovirus (Ad) infected cells can be secreted prior to progeny release and thereby regulate progeny spread. We aimed to investigate the mechanisms of fiber and penton base secretion in Ad2- or Ad5-infected A549 cells. Our flow cytometry analyses detected abundant surface fiber mo...

journal_title：Virology

authors： Yan Y,Zhang B,Hou W,Lin H,Rebetz J,Hong SS,Wang Y,Ran L,Fan X

更新日期：2017-05-01 00:00:00

abstract：:The infectivity in vivo, replication competence in vitro, and expression of viral genes of several molecularly cloned duck hepatitis B virus (DHBV) genomes were investigated. In addition, replication competence, core protein expression, and secretion of viral proteins were investigated for a grey heron hepatitis B vir...

journal_title：Virology

authors： Wildner G,Fernholz D,Sprengel R,Schneider R,Will H

更新日期：1991-11-01 00:00:00

abstract：:The HPV16 E7 oncoprotein and 17β-estradiol are important factors for the induction of premalignant lesions and cervical cancer. The study of these factors is crucial for a better understanding of cervical tumorigenesis. Here, we assessed the global gene expression profiles induced by the HPV16 E7 oncoprotein and/or 17...

journal_title：Virology

authors： Cortés-Malagón EM,Bonilla-Delgado J,Díaz-Chávez J,Hidalgo-Miranda A,Romero-Cordoba S,Uren A,Celik H,McCormick M,Munguía-Moreno JA,Ibarra-Sierra E,Escobar-Herrera J,Lambert PF,Mendoza-Villanueva D,Bermudez-Cruz RM,Gariglio P

更新日期：2013-12-01 00:00:00

abstract：:The unordered N-termini of parvovirus capsid proteins (Nt) are translocated through a channel at the icosahedral five-fold axis to serve for virus traffick. Heterologous peptides were genetically inserted at the Nt of MVM to study their functional tolerance to manipulations. Insertion of a 5T4-single-chain antibody at...

journal_title：Virology

authors： Sánchez-Martínez C,Grueso E,Carroll M,Rommelaere J,Almendral JM

更新日期：2012-10-10 00:00:00

abstract：:Single intradermal or intramuscular inoculations of GM-CSF DNA with the DNA prime for a simian-human immunodeficiency virus (SHIV)-89.6 vaccine, which consists of DNA priming followed by modified vaccinia Ankara (MVA) boosting, increased protection of both the blood and intestines against the acute phase of an intrare...

journal_title：Virology

authors： Lai L,Vödrös D,Kozlowski PA,Montefiori DC,Wilson RL,Akerstrom VL,Chennareddi L,Yu T,Kannanganat S,Ofielu L,Villinger F,Wyatt LS,Moss B,Amara RR,Robinson HL

更新日期：2007-12-05 00:00:00

abstract：:H4N8 subtype avian influenza viruses were isolated from shorebirds in eastern Hokkaido. All the isolates shared >99.7% nucleotide homology, and all the viral genes except for PB1 were highly related to those of A/red-necked stint/Australia/1/04. Thus, the isolates were regarded as PB1 reassortants. The most similar PB...

journal_title：Virology

authors： Bui VN,Ogawa H,Xininigen,Karibe K,Matsuo K,Awad SS,Minoungou GL,Yoden S,Haneda H,Ngo LH,Tamaki S,Yamamoto Y,Nakamura K,Saito K,Watanabe Y,Runstadler J,Huettmann F,Happ GM,Imai K

更新日期：2012-02-05 00:00:00

abstract：:The measles virus (MV) phosphoprotein (P) gene encodes three proteins, P, C, and V. The V protein is synthesized by pseudo-templated transcription, also designated as RNA editing: during P gene transcription one G residue is inserted at a defined position in about 50% of the mRNAs. To study the importance of sequence ...

journal_title：Virology

authors： Schneider H,Kaelin K,Billeter MA

更新日期：1997-01-20 00:00:00

abstract：:The circular single-stranded viral DNA (ssDNA) of filamentous phage is oriented in the virus with a hairpin forming sequence called mos at the leading end of the virion-the end that emerges from the cell first. In the experiments that originally defined mos it was also found to enhance virion production 100-fold, thou...

journal_title：Virology

authors： Bauer M,Smith GP

更新日期：1988-11-01 00:00:00

abstract：:Twelve avian reovirus strain 176 proteins, 10 structural (lambda 1, lambda 2, lambda 3, mu 1, mu 2/mu 2C, sigma 1, sigma 2, sigma 3, and sigma 4), and 2 nonstructural (mu NS and sigma NS) were identified and characterized by electrophoretic analysis of purified virions and infected cell lysates. Three of the identifie...

journal_title：Virology

authors： Ni Y,Ramig RF,Kemp MC

更新日期：1993-03-01 00:00:00

abstract：:Red sea bream iridovirus (RSIV) of the Iridoviridae family is a causative agent of lethal infections in many cultured marine fish species in southwestern Japan. RSIV-induced apoptosis was divided as follows: (1). cell shrinkage and rounding at the early apoptotic stage, (2). cell enlargement at the middle apoptotic st...

journal_title：Virology

authors： Imajoh M,Sugiura H,Oshima S

更新日期：2004-05-01 00:00:00

abstract：:Mouse hybridomas which produce monoclonal antibodies to the Autographa californica nuclear polyhedrosis virus (AcNPV) have been prepared and the protein to which each is directed has been determined. The antibody produced by clones 3F3 and 5E9 specifically bound polyhedron protein of MW 32,000 when used in immunoadsor...

journal_title：Virology

authors： Roberts PL,Naser W

更新日期：1982-10-30 00:00:00

abstract：:Although a live attenuated HIV vaccine is not currently considered for safety reasons, a strategy inducing both T cells and neutralizing antibodies to native assembled HIV-1 particles expressed by a replicating virus might mimic the advantageous characteristics of live attenuated vaccine. To this aim, we generated a l...

journal_title：Virology

authors： Guerbois M,Moris A,Combredet C,Najburg V,Ruffié C,Février M,Cayet N,Brandler S,Schwartz O,Tangy F

更新日期：2009-05-25 00:00:00

abstract：:Human papillomavirus type 6 (HPV 6) DNA was detected in an episomal form in DNA extracted from an invasive squamous carcinoma of the vulva. The viral DNA, designated HPV6-T70, was molecularly cloned. Restriction analysis of the HPV6-T70 genome revealed an insertion of approximately 35 bp in the 5' portion of the upstr...

journal_title：Virology

authors： Kasher MS,Roman A

更新日期：1988-07-01 00:00:00