Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue.

abstract：:The single-stranded DNA-binding protein LEF-3 of Autographa californica multinucleocapsid nucleopolyhedrovirus consists of 385 amino acid residues, forms oligomers, and promotes Mg2+-independent unwinding of DNA duplexes and annealing of complementary DNA strands. Partial proteolysis revealed that the DNA-binding doma...

journal_title：Virology

authors： Mikhailov VS,Okano K,Rohrmann GF

更新日期：2006-03-15 00:00:00

abstract：:Two noncomplementing vaccinia virus temperature-sensitive mutants, Cts8 and Cts26, were mapped to the A3L gene, which encodes the major virion structural protein, 4b. The two ts mutants display normal patterns of gene expression, DNA replication, telomere resolution, and protein processing during infection. Morphogene...

journal_title：Virology

authors： Kato SE,Strahl AL,Moussatche N,Condit RC

更新日期：2004-12-05 00:00:00

abstract：:The extraordinarily high level of genetic variation of HIV-1 env genes poses a challenge to obtain antibodies that cross-react with multiple subtype Env glycoproteins. To determine if cross-reactive monoclonal antibodies (mAbs) to highly conserved epitopes in HIV-1 envelope glycoproteins can be induced, we immunized m...

journal_title：Virology

authors： Gao F,Scearce RM,Alam SM,Hora B,Xia S,Hohm JE,Parks RJ,Ogburn DF,Tomaras GD,Park E,Lomas WE,Maino VC,Fiscus SA,Cohen MS,Moody MA,Hahn BH,Korber BT,Liao HX,Haynes BF

更新日期：2009-11-10 00:00:00

abstract：:Plasmid p12929 was shown to integrate into the chromosome of Corynebacterium glutamicum RM3 and BL15. The minimal integrating fragment was subsequently defined. The arms flanking the integrated plasmid (attL and attR) were identified, allowing for the determination of the attP and the attB attachment sites. The attB s...

journal_title：Virology

authors： Moreau S,Le Marrec C,Blanco C,Trautwetter A

更新日期：1999-03-01 00:00:00

abstract：:Parotid tumor agent was an early name for polyomavirus due to its ability to induce tumors (myoepitheliomas originating from the myoepithelial glandular tissues) in mice inoculated with polyomavirus (Py) as neonates. It has long been thought that these tumors directly follow productive infection by Py in epithelial ce...

journal_title：Virology

authors： Atencio IA,Meraz A,Villarreal LP

更新日期：1994-05-01 00:00:00

abstract：:In previous studies, a mutant (cp-RSV) of the RSV A2 strain derived from 52 serial cold passages in bovine embryonic tissue culture was highly attenuated in seropositive adults and children but caused upper respiratory tract disease in seronegative infants. We investigated the genetic basis for this attenuation phenot...

journal_title：Virology

authors： Connors M,Crowe JE Jr,Firestone CY,Murphy BR,Collins PL

更新日期：1995-04-20 00:00:00

abstract：:Human parainfluenza virus type 1 (hPIV1) and type 3 (hPIV3) initiate infection by sialic acid binding. Here, we investigated sialic acid linkage specificities for binding and infection of hPIV1 and hPIV3 by using sialic acid linkage-modified cells treated with sialidases or sialyltransferases. The hPIV1 is bound to on...

journal_title：Virology

authors： Fukushima K,Takahashi T,Ito S,Takaguchi M,Takano M,Kurebayashi Y,Oishi K,Minami A,Kato T,Park EY,Nishimura H,Takimoto T,Suzuki T

更新日期：2014-09-01 00:00:00

abstract：:HIV-1 entry into cells requires the interaction of both HIV-1 envelope proteins and membrane lipids. We investigated the mechanism of neutralization of HIV-1 infection of primary monocyte-derived macrophages (MDM) by a murine monoclonal antibody (mAb) WR321. WR321 specifically binds phosphatidylinositol-4-phosphate an...

journal_title：Virology

authors： Jobe O,Peachman KK,Matyas GR,Asher LV,Alving CR,Rao M

更新日期：2012-09-01 00:00:00

abstract：:The bovine herpesvirus 1 (BHV-1) U(S) ORF8 protein with homology to the Us9 protein of other alphaherpesviruses induces apoptosis in rabbit kidney (RK13) cells without the presence of other BHV-1-encoded proteins. In this article, we have characterized the cytotoxicity and growth behavior of a BHV-1 recombinant, BHV-1...

journal_title：Virology

authors： Nakamichi K,Matsumoto Y,Otsuka H

更新日期：2002-12-05 00:00:00

abstract：:Epstein-Barr virus (EBV) is a herpesvirus that transforms B-cells (B-LCL) and has undergone intense scrutiny owing to its association with Burkitt's lymphoma, nasopharyngeal carcinoma, and immunoblastic lymphomas. B-LCL have also proven useful in the study of human immunology. We describe a novel system for inducing e...

journal_title：Virology

authors： Curiel TJ,Cook DR,Bogedain C,Jilg W,Harrison GS,Cotten M,Curiel DT,Wagner E

更新日期：1994-02-01 00:00:00

abstract：:The 3' untranslated regions (UTRs) of many plant viral RNAs contain cap-independent translation elements (3' CITEs). Among the 3' CITEs, the Barley yellow dwarf virus (BYDV)-like translation elements (BTEs) form a structurally variable and widely distributed group. Viruses in three genera were known to harbor 3' BTEs,...

journal_title：Virology

authors： Wang Z,Kraft JJ,Hui AY,Miller WA

更新日期：2010-06-20 00:00:00

abstract：:Replication and transmission of avian influenza virus in humans poses a pandemic threat. The molecular determinants that facilitate this process are not well understood. We used DBA/2 mice to identify viral factors that mediate the difference in pathogenesis between a virulent (H7N3) and a non-virulent (H7N9) avian in...

journal_title：Virology

authors： DesRochers BL,Chen RE,Gounder AP,Pinto AK,Bricker T,Linton CN,Rogers CD,Williams GD,Webby RJ,Boon AC

更新日期：2016-07-01 00:00:00

abstract：:Phylogenetic analysis of the N8 neuraminidase (NA) genes from 18 influenza A viruses, representing equine and avian hosts in different geographic locations, revealed three major lineages: (i) currently circulating equine 2 viruses; (ii) avian viruses isolated in the Eurasian region, including A/Equine/Jilin/1/89, a re...

journal_title：Virology

authors： Saito T,Kawaoka Y,Webster RG

更新日期：1993-04-01 00:00:00

abstract：:The Gardner (GA) and Snyder-Theilen (ST) isolates of feline sarcoma virus (FeSV) represent genetic recombinants between feline leukemia virus (FeLV) and transformation-specific sequences (v-fes gene) of cat cellular origin. A related transforming gene (v-fps), common to the Fujinami, PRC II, and UR 1 strains of avian ...

journal_title：Virology

authors： Groffen J,Heisterkamp N,Shibuya M,Hanafusa H,Stephenson JR

更新日期：1983-03-01 00:00:00

abstract：:Economic loss due to viral endothelial cell necrosis of eel (VECNE) of Anguilla japonica is a serious problem for the cultured Japanese eel market. However, the viral genome responsible for VECNE is unknown. We recently developed a rapid determination system for viral nucleic acid sequences (RDV) to determine viral ge...

journal_title：Virology

authors： Mizutani T,Sayama Y,Nakanishi A,Ochiai H,Sakai K,Wakabayashi K,Tanaka N,Miura E,Oba M,Kurane I,Saijo M,Morikawa S,Ono S

更新日期：2011-03-30 00:00:00

abstract：:Ts1, a temperature-sensitive mutant of Moloney murine leukemia virus-TB (MoMuLV-TB), causes a progressive hindlimb paralytic disease in susceptible strains of mice. Previously, it has been shown that a single amino acid substitution, Val-25----Ile in gPr80env, is responsible for the temperature sensitivity, inefficien...

journal_title：Virology

authors： Kamps CA,Lin YC,Wong PK

更新日期：1991-10-01 00:00:00

abstract：:Viral vector particles derived from murine leukemia virus (MLV) mediate highly efficient stable gene transfer used in gene therapeutic approaches and in the generation of transgenic cell lines. However, the establishment of stable viral packaging cells (VPCs) is a time-consuming challenge. To overcome this limitation,...

journal_title：Virology

authors： Berg K,Schäfer VN,Bartnicki N,Eggenschwiler R,Cantz T,Stitz J

更新日期：2019-05-01 00:00:00

abstract：:The simian parainfluenza virus 5 (SV5) V/P gene encodes two proteins: V and the phosphoprotein P. The V and P proteins are amino coterminal for 164 residues, but they have unique carboxyl termini. The unique carboxyl terminus of V contains seven cysteine residues, resembles a zinc finger, and binds two atoms of zinc. ...

journal_title：Virology

authors： Lin GY,Paterson RG,Richardson CD,Lamb RA

更新日期：1998-09-15 00:00:00

abstract：:Ten human genital invasive squamous cell carcinomas and five human premalignant tissues were analyzed for the presence of selected sets of herpes simplex virus 2 (HSV-2) DNA sequences. Two vulvar tumors and one vulvar dysplastic tissue were found to contain DNA sequences homologous to the BglII O fragment (coordinates...

journal_title：Virology

authors： Manservigi R,Cassai E,Deiss LP,Di Luca D,Segala V,Frenkel N

更新日期：1986-11-01 00:00:00

abstract：:This study was initiated to evaluate the in vivo infectivity and pathogenicity of a group of recombinant feline leukemia viruses (rFeLVs) previously generated by in vitro forced recombination between a FeLV subgroup A virus (FeLV-A) and an endogenous FeLV (enFeLV) envelope (env) element (Sheets et al., 1992, Virology ...

journal_title：Virology

authors： Pandey R,Bechtel MK,Su Y,Ghosh AK,Hayes KA,Mathes LE,Roy-Burman P

更新日期：1995-12-20 00:00:00

abstract：:We show that the product of the polarity suppression (psu) gene from bacteriophage P4 associates with P4 capsids. This association can occur when Psu is (i) provided in vivo from the P4 genome or from a plasmid or (ii) provided in vitro by mixing viable phage particles with Psu protein. Psu is unable to associate with...

journal_title：Virology

authors： Isaksen ML,Rishovd ST,Calendar R,Lindqvist BH

更新日期：1992-06-01 00:00:00

abstract：:Avipoxviruses are significant pathogens infecting a wide range of wild and domestic bird species globally. Here, we describe a novel genome sequence of magpiepox virus (MPPV) isolated from an Australian magpie. In the present study, histopathologically confirmed cutaneous pox lesions were used for transmission electro...

journal_title：Virology

authors： Sarker S,Batinovic S,Talukder S,Das S,Park F,Petrovski S,Forwood JK,Helbig KJ,Raidal SR

更新日期：2020-01-15 00:00:00

abstract：:The elucidation of the antigenic structure of the S glycoprotein of murine coronaviruses will provide further understanding of the complex pathogenicity of these viruses. In order to identify linear antigenic determinants, the primary structure of the S glycoprotein of murine hepatitis virus strain A59 was analyzed wi...

journal_title：Virology

authors： Daniel C,Lacroix M,Talbot PJ

更新日期：1994-08-01 00:00:00

abstract：:The function of rice dwarf virus segment 11 and the corresponding segments of other phytoreoviruses is not yet determined. The amino acid sequence of Pns11, encoded by segment 11, contains a putative zinc finger and five flanking basic regions at the C-terminus. The full-length Pns11 protein and three truncated deriva...

journal_title：Virology

authors： Xu H,Li Y,Mao Z,Li Y,Wu Z,Qu L,An C,Ming X,Schiemann J,Casper R,Chen Z

更新日期：1998-01-20 00:00:00

abstract：:The prototype strain of Flanders virus (61-7484) has been adapted to grow in Vero cell cultures and a plaque assay has been developed. Electron micrographs of infected cells revealed rod-shaped virions budding in clusters from the plasma membrane, consistent with the tentative classification of Flanders virus as a mem...

journal_title：Virology

authors： Boyd KR,Whitaker-Dowling P

更新日期：1988-04-01 00:00:00

abstract：:We recently reported the phenomenon of retroviral insertion into a herpesvirus (Isfort et al., (1992) Proc. Natl. Acad. Sci. USA 89, 991-995). We have now isolated Marek's disease virus (MDV) clones that carry retroviral inserts. Retroviral LTR insertion has the potential to activate or inactivate herpesvirus genes le...

journal_title：Virology

authors： Kost R,Jones D,Isfort R,Witter R,Kung HJ

更新日期：1993-01-01 00:00:00

abstract：:The sequence of gene VI from figwort mosaic virus (FMV) clone x4 was determined and compared with that previously published for FMV clone DxS. Both clones originated from the same virus isolation, but the virus used to clone DxS was propagated extensively in a host of a different family prior to cloning whereas that u...

journal_title：Virology

authors： Sanger M,Daubert S,Goodman RM

更新日期：1991-06-01 00:00:00

abstract：:Our recent results demonstrated that bile acids facilitate virus escape from the endosomes into the cytoplasm for successful replication of porcine enteric calicivirus (PEC). We report a novel finding that bile acids can be substituted by cold treatment for endosomal escape and virus replication. This endosomal escape...

journal_title：Virology

authors： Shivanna V,Kim Y,Chang KO

更新日期：2015-09-01 00:00:00

abstract：:We have determined the nucleotide sequence of the RNA2 segment of the Nudaurelia capensis omega virus genome. It was found to consist of 2448 nucleotides and contained one long open reading frame (ORF) encoding the 644 residue capsid protein. The deduced amino acid sequence of this protein reveals a positively charged...

journal_title：Virology

authors： Agrawal DK,Johnson JE

更新日期：1992-10-01 00:00:00

abstract：:Prostaglandin E₂ (PGE₂) is an arachidonic acid (AA)-derived signaling molecule that can influence host immune responses to infection or vaccination. In this study, we investigated PGE₂ production in vitro by cells infected with the poxvirus vaccine strain, modified vaccinia Ankara virus (MVA). Human THP-1 cells, murin...

journal_title：Virology

authors： Pollara JJ,Spesock AH,Pickup DJ,Laster SM,Petty IT

更新日期：2012-07-05 00:00:00