Abstract：
:The sequence of gene VI from figwort mosaic virus (FMV) clone x4 was determined and compared with that previously published for FMV clone DxS. Both clones originated from the same virus isolation, but the virus used to clone DxS was propagated extensively in a host of a different family prior to cloning whereas that used to clone x4 was not. Differences in the amino acid sequence inferred from the DNA sequences occurred in two clusters. An N-terminal conserved region preceded two regions of variation separated by a central conserved region. Variation in cauliflower mosaic virus (CaMV) gene VI sequences, all of which were derived from virus isolates from hosts from one host family, was similar to that seen in the FMV comparison, though the extent of variation was less. Alignment of gene VI domains from FMV and CaMV revealed regions of amino acid sequence identical in both viruses within the conserved regions. The similarity in the pattern of conserved and variable domains of these two viruses suggests common host-interactive functions in caulimovirus gene VI homologues, and possibly an analogy between caulimoviruses and certain animal viruses in the influence of the host on sequence variability of viral genes.
journal_name
Virologyjournal_title
Virologyauthors
Sanger M,Daubert S,Goodman RMdoi
10.1016/0042-6822(91)90624-ksubject
Has Abstractpub_date
1991-06-01 00:00:00pages
830-4issue
2eissn
0042-6822issn
1096-0341journal_volume
182pub_type
杂志文章相关文献
VIROLOGY文献大全abstract：:Missing contact footprinting with formic acid as a modifying reagent was used to examine specific IE-1 binding contacts to double-stranded oligonucleotides that contained either a consensus hr repeat sequence or a sequence from the pe38 promoter, which is down regulated by IE-1. The hr repeat sequences contain two con...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.2000.0452
更新日期：2000-08-15 00:00:00
abstract：:The DNAs of the Cas-Br-E MuLV-induced leukemias always contain somatically acquired mink cell focus-forming (MCF) recombinant proviruses. MCF recombinants could be involved during leukemogenesis at both preleukemic times and in late-stage tumors. Among the Cas-Br-E-induced non-T-, non-B-cell leukemias, viral integrati...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(92)90241-g
更新日期：1992-12-01 00:00:00
abstract：:The recent development of arterivirus full-length cDNA clones makes possible the construction of chimeric arteriviruses for fundamental and applied studies. Using an equine arteritis virus (EAV) infectious cDNA clone, we have engineered chimeras in which the ectodomains of the two major envelope proteins, the glycopro...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.2001.1074
更新日期：2001-09-30 00:00:00
abstract：:Rat 3Y1 cells were infected by AKR virus through microinjection of molecularly cloned proviral DNA. Based on a strong immunofluorescence using anti-p30 as an antiserum a cell clone (RESA-2) was selected that had a high expression of viral antigens. Subsequent restriction analysis of its DNA revealed that the RESA-2 cl...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(83)90361-6
更新日期：1983-01-30 00:00:00
abstract：:Tombusviruses replicate on pre-existing organelles such as peroxisomes or mitochondria, the membranes of which become extensively reorganized into multivesicular bodies (MVBs) during the infection process. Cucumber necrosis virus (CNV) has previously been shown to replicate in association with peroxisomes in yeast. We...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2013.12.035
更新日期：2014-03-01 00:00:00
abstract：:Rotavirus infection was studied in adult nude mice (BALB/c background), alpha beta or gamma delta and alpha beta/gamma delta T cell receptor (TCR) knockout (-/-) mice (C57BL/6 and C57BL/6 x 129 backgrounds), and SCID mice (C57BL/6 background). The gamma delta TCR -/- mice cleared infection just like control mice. All ...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1997.8843
更新日期：1997-11-24 00:00:00
abstract：:The M128L myxoma virus gene expresses a five-membrane spanning cell surface protein with significant amino acid homology to the cellular CD47 proteins. CD47, also called integrin-associated protein (IAP), is associated with the modulation of leukocyte adhesion, motility, activation, and phagocytosis. Creation of an M1...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2005.03.037
更新日期：2005-06-20 00:00:00
abstract：:Computational analysis of feline immunodeficiency virus (FIV) RNA sequences indicated that common FIV strains contain a rev response element (RRE) defined by a long unbranched hairpin with 6 stem-loop sub-domains, termed stem-loop A (SLA). To examine the role of the RNA secondary structure of the RRE, mutational analy...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2010.04.009
更新日期：2010-09-01 00:00:00
abstract：:Mutations disrupting helicase domain motifs of the Tobacco mosaic virus 126/183-kDa proteins were investigated for their effect on replicase function and assembly. These mutations inhibited virus replication but did not affect 126-kDa induced N gene resistance or RNAi suppression. However, in vivo expressed 126-kDa mo...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2010.03.019
更新日期：2010-07-05 00:00:00
abstract：:Adsorption and one-step growth experiments performed with blue-green algal virus (BGAV) LPP-1 under normal conditions revealed a slow adsorption rate, in comparison with bacteriophage systems, followed by a 7-hour latent period. The burst size was approximately 100 virus particles per cell. The molecular weight of the...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(67)90036-0
更新日期：1967-08-01 00:00:00
abstract：:Open reading frame 89 (ORF89) is one of the three genes that are believed to be involved in the latent infection of white spot syndrome virus (WSSV). Here, we report the structure and functional characterization of ORF89. cDNA sequencing, 5' RLM-RACE, and 3' RLM-RACE showed that ORF89 gene is transcribed into an unspl...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2004.05.005
更新日期：2004-07-20 00:00:00
abstract：:The mechanism by which lentivirus envelope (Env) glycoproteins are packaged into budding virions is poorly understood. Simian immunodeficiency virus (SIV) contains an Env protein with an unusually long cytoplasmic tail. To investigate the role of this domain in the incorporation of the SIV Env into virions, we generat...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.2001.0869
更新日期：2001-05-10 00:00:00
abstract：:In 1943 Burnet reported on changes in the hemagglutinating properties of human influenza virus which occurred during adaptation of the virus to growth in chicken eggs. Only recently has direct evidence been presented that these changes affect the antigenic properties of the virus. Schild et al. (G. C. Schild, J. S. Ox...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(85)90105-9
更新日期：1985-05-01 00:00:00
abstract：:The recent development of in vitro hepatitis C virus (HCV) RNA replication systems has provided useful tools for studying the intracellular anti-HCV activity of ribavirin. Ribavirin has been shown to: (1) induce "error catastrophe" in poliovirus, Proc. Natl. Acad. Sci. USA 98, 6895-6900), (2) be a pseudo-substrate of ...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/s0042-6822(03)00152-1
更新日期：2003-06-05 00:00:00
abstract：:A nonaphid transmissible (NAT) variant of tobacco vein mottling virus (TVMV) was used to test the hypothesis that the viral coat protein (CP) plays a role in determining aphid transmissibility. Comparison of the nucleotide sequences in the coat protein cistron of an aphid transmissible isolate (TVMV-AT) with that of T...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(90)90389-9
更新日期：1990-09-01 00:00:00
abstract：:When hemagglutinin (HA) and neuraminidase (NA) are presented together on an intact influenza virus particle, the antigens are competitive, with HA dominant over NA in T- and B-cell priming. Immunization with mixtures of purified HA and NA eliminates antigenic competition between HA and NA, as well as between N1-N2 NA ...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1996.0581
更新日期：1996-11-01 00:00:00
abstract：:Immunization with heat-inactivated herpes simplex virus type 1 (HSV-1) 2-5 days before ocular infection reduced the frequency of establishment of latent HSV-1 infection in the trigeminal ganglion (TG); this induction of resistance coincided with reduced expression of IFN-gamma mRNA in the TG. Immunization with unrelat...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1997.8738
更新日期：1997-09-29 00:00:00
abstract：:The primary cell types that sustain polyomavirus (Py) replication following intranasal infection as well as the nature of the host cellular response to Py were unknown. As this is an essential and specific site for virus entry, it seems likely that viral gene function must be adapted to these mucosal tissues. Using im...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1999.0030
更新日期：2000-01-05 00:00:00
abstract：:During replication, the lengthy genome of dsDNA viruses is translocated with remarkable velocity into the limited space within the preformed procapsid. We previously found that a viral-encoded RNA (pRNA) played a key role in bacterial virus phi29 DNA translocation. Design of mutant pRNA sets containing two and three i...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.2000.0771
更新日期：2001-03-15 00:00:00
abstract：:In order to determine the location and biological significance of the acid-induced conformational change in influenza virus hemagglutinin (HA) reported by Skehel et al., monoclonal antibodies were prepared to the molecule before and after treatment at pH 5.0. These antibodies together with monoclonal antibodies to the...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/s0042-6822(83)80015-4
更新日期：1983-04-30 00:00:00
abstract：:Parotid tumor agent was an early name for polyomavirus due to its ability to induce tumors (myoepitheliomas originating from the myoepithelial glandular tissues) in mice inoculated with polyomavirus (Py) as neonates. It has long been thought that these tumors directly follow productive infection by Py in epithelial ce...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1994.1254
更新日期：1994-05-01 00:00:00
abstract：:To address the mechanisms of host-virus adaptation and pathogenesis of lentiviral infections, we compared the evolution of the same isolate of simian immunodeficiency virus (SIVsmm9) in two different situations: nonpathogenic infection of its natural host, the sooty mangabey, and AIDS-inducing infection of a new host,...
journal_title：Virology
pub_type： 杂志文章
doi：10.1006/viro.1998.9217
更新日期：1998-07-20 00:00:00
abstract：:CD8 T cells play an important role in controlling Ebola infection and in mediating vaccine-induced protective immunity, yet little is known about antigenic targets in Ebola that are recognized by CD8 T cells. Overlapping peptides were used to identify major histocompatibility complex class I-restricted epitopes in mic...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2003.09.016
更新日期：2004-01-05 00:00:00
abstract：:Equine infectious anemia virus (EIAV) is responsible of acute disease episodes characterized by fever, anemia, thrombocytopenia and anorexia in equids. The high mutation rate in EIAV genome limited the number of full genome sequences availability. In the present study, we used the SureSelect target enrichment system w...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2019.08.016
更新日期：2019-11-01 00:00:00
abstract：:In wild-type human parainfluenza virus type 2 (WT HPIV2), one gene (the P/V gene) encodes both the polymerase-associated phosphoprotein (P) and the accessory V protein. We generated a HPIV2 virus (rHPIV2-V(ko)) in which the P/V gene encodes only the P protein to examine the role of V in replication in vivo and as a po...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2009.11.018
更新日期：2010-02-20 00:00:00
abstract：:A viroid has been purified from avocado leaves infected by sunblotch disease and designated the avocado sunblotch viroid. It is a covalently closed circular RNA molecule with a molecular weight lower than that of chrysanthemum stunt viroid and citrus exocortis viroid while hybridization analysis with 32P-labeled compl...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/0042-6822(79)90045-x
更新日期：1979-11-01 00:00:00
abstract：:Porcine circovirus type 2 (PCV2) is an economically important cause of post-weaning multisystemic wasting syndrome (PMWS) in weanling piglets. Current commercial vaccines against PCV2 are highly effective. Yet, a recurring emergence of new genotypes in vaccinated herds necessitates a better understanding of protective...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2019.11.008
更新日期：2020-01-15 00:00:00
abstract：:Begomoviruses (family Geminiviridae) are responsible for many economically important crop diseases worldwide. The majority of these diseases are caused by bipartite begomovirus infections, although a rapidly growing number of diseases of the Old World are associated with monopartite begomoviruses. With the exception o...
journal_title：Virology
pub_type： 杂志文章,随机对照试验,评审
doi：10.1016/j.virol.2005.09.042
更新日期：2006-01-05 00:00:00
abstract：:Chikungunya virus (CHIKV) infection leads to activation of innate immune response by triggering Toll-like receptor (TLR) pathways resulting in elevated cytokines and type-I interferon levels. Genetic variations of these genes may influence human CHIKV-susceptibility and disease progression. Present study aimed to iden...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2017.08.009
更新日期：2017-11-01 00:00:00
abstract：:We report herein that vesicular stomatitis virus (VSV) induced a concurrent primary Th1 (T helper 1) and Th2 cytokine response detectable ex vivo. Liposome-encapsulated clodronate-mediated elimination of CD8- marginal dendritic cells (DCs) and splenic macrophages (m Phi), but not CD8+ interdigitating DCs, prior to inf...
journal_title：Virology
pub_type： 杂志文章
doi：10.1016/j.virol.2005.07.031
更新日期：2005-11-25 00:00:00
