当前位置： SCI文献检索 > VIROLOGY期刊下所有文献 > Transforming genes of avian (v-fps) and mammalian (v-fes) retroviruses correspond to a common cellular locus.

Transforming genes of avian (v-fps) and mammalian (v-fes) retroviruses correspond to a common cellular locus.

Abstract：

:The Gardner (GA) and Snyder-Theilen (ST) isolates of feline sarcoma virus (FeSV) represent genetic recombinants between feline leukemia virus (FeLV) and transformation-specific sequences (v-fes gene) of cat cellular origin. A related transforming gene (v-fps), common to the Fujinami, PRC II, and UR 1 strains of avian sarcoma virus has also been described. Translational products of each of these recombinant virus isolates are expressed in the form of polyproteins exhibiting protein kinase activities with specificity for tyrosine residues. In the present study, v-fes and v-fps homologous sequences of GA-FeSV, ST-FeSV, and Fujinami sarcoma virus (FSV) are defined and these independently derived transforming genes are shown to correspond to a common cellular genetic locus which has remained highly conserved throughout vertebrate evolution.

journal_name

Virology

journal_title

Virology

authors

Groffen J,Heisterkamp N,Shibuya M,Hanafusa H,Stephenson JR

doi

10.1016/0042-6822(83)90219-2

subject

Has Abstract

pub_date

1983-03-01 00:00:00

pages

480-6

issue

2

eissn

0042-6822

issn

1096-0341

journal_volume

125

pub_type

杂志文章

相关文献

VIROLOGY文献大全
  • CpG methylation of HPV 16 LCR at E2 binding site proximal to P97 is associated with cervical cancer in presence of intact E2.

    abstract：:Human papillomavirus type 16 (HPV-16) E2 protein negatively regulates transcription of the E6 and E7 genes. This study was done to test the hypothesis that methylation of the HPV 16 long control region (LCR) is overrepresented among cervical cancer (CaCx) cases compared to cytologically normal controls harboring intac...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2006.06.018

    authors： Bhattacharjee B,Sengupta S

    更新日期：2006-10-25 00:00:00

  • CCAAT/enhancer binding protein beta binds to and activates the P670 promoter of human papillomavirus type 16.

    abstract：:The P670 promoter of HPV16 directs transcription of the virus late genes in the differentiating epithelium. We found that CCAAT/enhancer binding protein beta (C/EBPbeta), a key transcription factor that induces the terminal differentiation of keratinocytes, enhanced the P670-driven transcription in transient reporter ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2005.10.025

    authors： Kukimoto I,Takeuchi T,Kanda T

    更新日期：2006-03-01 00:00:00

  • Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone.

    abstract：:Attenuated mutants of Venezuelan equine encephalitis virus (VEE) were isolated by selection for rapid penetration of cultured cells (R. E. Johnston and J. F. Smith, 1988, Virology 162, 437-443). Sequence analysis of these mutants identified candidate attenuating mutations at four loci in the VEE E2 glycoprotein gene: ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(91)90114-q

    authors： Davis NL,Powell N,Greenwald GF,Willis LV,Johnson BJ,Smith JF,Johnston RE

    更新日期：1991-07-01 00:00:00

  • First outbreak of callitrichid hepatitis in Germany: genetic characterization of the causative lymphocytic choriomeningitis virus strains.

    abstract：:Callitrichid hepatitis (CH) is a highly fatal, rodent-borne zoonosis of New World primates (family Callitrichidae) caused by lymphocytic choriomeningitis virus (LCMV). It is unclear whether virulence in Callitrichidae is associated with specific genetic or phylogenetic markers of the virus as only a partial S RNA sequ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2001.0909

    authors： Asper M,Hofmann P,Osmann C,Funk J,Metzger C,Bruns M,Kaup FJ,Schmitz H,Günther S

    更新日期：2001-06-05 00:00:00

  • Tyrosine sulfation of varicella-zoster virus envelope glycoprotein gpl.

    abstract：:Sulfation is a common post-translational modification of secreted and membrane proteins, with the sulfate attached to tyrosine residues or to glycan side-chains. I have shown that varicella-zoster virus (VZV) envelope glycoproteins gpI, gpII, and gpIII can be labeled with [35S]sulfate. The predominant VZV glycoprotein...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1993.1576

    authors： Edson CM

    更新日期：1993-11-01 00:00:00

  • Zoonotic potential of highly pathogenic avian H7N3 influenza viruses from Pakistan.

    abstract：:H5 and H7 avian influenza viruses can become highly pathogenic in chickens after interspecies transmission. These viruses have transmitted directly to humans from birds in Eurasia and Africa (H5N1), the Netherlands (H7N7), and Canada (H7N3). Here we report antigenic, sequence, and phylogenetic analyses of H7N3 viruses...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2009.05.008

    authors： Aamir UB,Naeem K,Ahmed Z,Obert CA,Franks J,Krauss S,Seiler P,Webster RG

    更新日期：2009-08-01 00:00:00

  • Antiviral activity of natural and recombinant human leukocyte interferons in tobacco protoplasts.

    abstract：:Several purified species of human leukocyte interferon, including recombinant interferons, inhibit the multiplication of tobacco mosaic virus (TMV) in tobacco protoplasts derived from various cultivars. Viral RNA accumulation was determined by dot-blot hybridization to specific cDNA probes, and virus antigen was deter...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(85)90456-8

    authors： Rosenberg N,Reichman M,Gera A,Sela I

    更新日期：1985-01-15 00:00:00

  • Replication of minute virus of mice DNA in adenovirus-infected or adenovirus-transformed cells.

    abstract：:The effect of adenovirus infection or transformation on the DNA replication of Minute Virus of Mice (MVM) was studied in human fibroblast cell lines. In WI38, HeLa, and 293 cells MVM infection allowed production of viral NS-1 and capsid proteins with or without adenovirus 2 (Ad2) co-infection. However, MVM DNA replica...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(90)90010-o

    authors： Fox E,Moen PT Jr,Bodnar JW

    更新日期：1990-06-01 00:00:00

  • The minute virus of mice exploits different endocytic pathways for cellular uptake.

    abstract：:The minute virus of mice, prototype strain (MVMp), is a non-enveloped, single-stranded DNA virus of the family Parvoviridae. Unlike other parvoviruses, the mechanism of cellular uptake of MVMp has not been studied in detail. We analyzed MVMp endocytosis in mouse LA9 fibroblasts and a tumor cell line derived from epith...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2015.02.054

    authors： Garcin PO,Panté N

    更新日期：2015-08-01 00:00:00

  • Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity.

    abstract：:Tick-borne flaviviruses are maintained in nature in an enzootic cycle involving a tick vector and a vertebrate host. Thus, the virus replicates in two disparate hosts, each providing selective pressures that can influence virus replication and pathogenicity. To identify viral determinants associated with replication i...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2008.08.030

    authors： Mitzel DN,Best SM,Masnick MF,Porcella SF,Wolfinbarger JB,Bloom ME

    更新日期：2008-11-25 00:00:00

  • Membrane topology of coronavirus E protein.

    abstract：:Coronavirus small envelope protein E has two known biological functions: it plays a pivotal role in virus envelope formation, and the murine coronavirus E protein induces apoptosis in E protein-expressing cultured cells. The E protein is an integral membrane protein. Its C-terminal region extends cytoplasmically in th...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2001.0818

    authors： Maeda J,Repass JF,Maeda A,Makino S

    更新日期：2001-03-15 00:00:00

  • Functional analysis of bipartite begomovirus coat protein promoter sequences.

    abstract：:We demonstrate that the AL2 gene of Cabbage leaf curl virus (CaLCuV) activates the CP promoter in mesophyll and acts to derepress the promoter in vascular tissue, similar to that observed for Tomato golden mosaic virus (TGMV). Binding studies indicate that sequences mediating repression and activation of the TGMV and ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2008.03.012

    authors： Lacatus G,Sunter G

    更新日期：2008-06-20 00:00:00

  • The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response.

    abstract：:Encephalitis is a rare, but serious complication from vaccination against smallpox using replication competent strains of vaccinia virus. In this report we describe mutants of vaccinia virus, containing N-terminal deletions of the vaccinia virus interferon resistance gene, E3L, that are attenuated for neuropathogenesi...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2005.01.006

    authors： Brandt T,Heck MC,Vijaysri S,Jentarra GM,Cameron JM,Jacobs BL

    更新日期：2005-03-15 00:00:00

  • Isolation of a monoclonal antibody that recognizes the origin binding domain of JCV, but not SV40, large T-antigen.

    abstract：:Within immunocompromised populations, the JC polyomavirus is the cause of the often-fatal disease Progressive Multifocal Leukoencephalopathy (PML). JC virus encodes a protein, termed T-antigen (T-ag), which is essential for its replication and pathogenicity. Previous studies of JCV T-ag have, in general, used antibodi...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2016.07.006

    authors： Grubman SA,Shin J,Phelan PJ,Gong A,Can H,Dilworth R,Kini SK,Gagnon D,Archambault J,Meinke G,Bohm A,Jefferson DM,Bullock PA

    更新日期：2016-10-01 00:00:00

  • High levels of IL-4 and IL-10 mRNA and low levels of IL-2, IL-9 and IFN-gamma mRNA in MuLV-induced lymphomas.

    abstract：:The expression of cytokines may influence the development of lymphoma in retrovirally infected animals in at least two ways: (1) cytokines in the tumor environment may stimulate the proliferation of tumor cells and/or (2) cytokines in the tumor environment may diminish the cell-mediated antitumor immune response. To e...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1999.9846

    authors： Beaty RM,Rulli K,Bost KL,Pantginis J,Lenz J,Levy LS

    更新日期：1999-09-01 00:00:00

  • A human T-cell line resistant to cytopathic effects of the human immunodeficiency virus (HIV).

    abstract：:Infection of human helper T lymphocytes with the human immunodeficiency virus (HIV) results in a rapid induction of cytopathic effects and cell lysis. We isolated a variant of the human T-lymphoblastoid cell line, CEM, that is fully susceptible to HIV infection but resistant to virally induced cytopathic effects. Expo...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(87)90434-x

    authors： Casareale D,Stevenson M,Sakai K,Volsky DJ

    更新日期：1987-01-01 00:00:00

  • Origin of the hemagglutinin gene of H3N2 influenza viruses from pigs in China.

    abstract：:Influenza viruses of the H3N2 subtype similar to Aichi/2/68 and Victoria/3/75 persist in pigs many years after their antigenic counterparts have disappeared from humans (Shortridge et al. (1977). Science 19, 1454-1455). To provide information on the mechanism of conservation of these influenza viruses in pigs, the hem...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(88)90405-9

    authors： Kida H,Shortridge KF,Webster RG

    更新日期：1988-01-01 00:00:00

  • Human T-cell leukemia virus type II: primary structure analysis of the major internal protein, p24 and the nucleic acid binding protein, p15.

    abstract：:The 24,000-molecular-weight major internal protein (p24) and the 15,000-molecular-weight nucleic acid binding protein (p15) of human T-cell leukemia virus type II (HTLV-II) were subjected to amino acid composition and amino-terminal amino acid sequence analysis. A comparison of amino acid composition of p24 and p15 of...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(85)90434-9

    authors： Devare SG,Kim Y,Fox JL,Getchell J,Cabradilla C,Kalyanaraman VS

    更新日期：1985-04-15 00:00:00

  • Minimum requirements for specific binding of RNA and coat protein of alfalfa mosaic virus.

    abstract：:Coat protein-protected fragments of alfalfa mosaic virus RNA (AlMV-RNA) and tobacco streak virus RNA (TSV-RNA), which were isolated as described [D. Zuidema, M. F. A. Bierhuizen, B. J. C. Cornelissen, J. F. Bol, and E. M. J. Jaspars (1983)Virology, 125, 361-369], were tested for their ability to rebind AlMV coat prote...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(84)90165-x

    authors： Zuidema D,Cool RH,Jaspars EM

    更新日期：1984-07-30 00:00:00

  • Serological characterization of human T-cell leukemia (lymphotropic) virus, type I (HTLV-I) small envelope protein.

    abstract：:Murine monoclonal antibodies were developed against the protein products produced by murine C127 cells which had been transfected with a recombinant plasmid clone containing the human T-cell leukemia (lymphotropic) virus type I (HTLV-I) proviral DNA coding regions for part of env, px, and the 3' LTR. Four antibodies w...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(86)90270-9

    authors： Newman MJ,Baker IT,Reitz MS,Eiden M,Blattner WA,Gallo RC,Mann DL

    更新日期：1986-04-15 00:00:00

  • Human papillomavirus 16 E6 variants differ in their dysregulation of human keratinocyte differentiation and apoptosis.

    abstract：:L83V-related variants of human papillomavirus (HPV) 16 E6, exemplified by the Asian-American variant Q14H/H78Y/L83V, were shown to be more prevalent than E6 prototype in progressing lesions and cervical cancer. We evaluated functions relevant to carcinogenesis for the E6 variants L83V, R10/L83V and Q14H/H78Y/L83V as w...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2008.09.036

    authors： Zehbe I,Richard C,DeCarlo CA,Shai A,Lambert PF,Lichtig H,Tommasino M,Sherman L

    更新日期：2009-01-05 00:00:00

  • Maize chlorotic mottle machlomovirus and wheat streak mosaic rymovirus concentrations increase in the synergistic disease corn lethal necrosis.

    abstract：:Corn lethal necrosis (CLN) is caused by the synergistic interaction between maize chlorotic mottle machlomovirus (MCMV) and any potyvirus which infects cereals. Interactions between MCMV and wheat streak mosaic rymovirus (WSMV) in N28Ht corn produced MCMV concentrations that averaged 3.3- to 11.2-fold higher in doubly...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1997.8989

    authors： Scheets K

    更新日期：1998-03-01 00:00:00

  • Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry.

    abstract：:Human nectin-1 (HveC, Prr1), a member of the immunoglobulin superfamily and a receptor for the entry of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-1), binds to viral gD. For HSV-1, HSV-2, and PRV, the gD-binding region of nectin-1 has been localized to the N-...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2001.0989

    authors： Geraghty RJ,Fridberg A,Krummenacher C,Cohen GH,Eisenberg RJ,Spear PG

    更新日期：2001-07-05 00:00:00

  • The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC.

    abstract：:It was recently proposed that HIV RT mutations that decrease RNase H activity increase zidovudine (AZT) resistance by delaying the degradation of the RNA template, allowing more time for AZTMP excision from the 3' end of the viral DNA. This predicts that suboptimal concentrations of an RNase H Inhibitor (RNHI), which ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2011.08.010

    authors： Davis CA,Parniak MA,Hughes SH

    更新日期：2011-10-25 00:00:00

  • Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression.

    abstract：:The influenza PA-X protein is translated from the PA open reading frame from frameshifting and suppresses cellular gene expression due to its ribonuclease activity. We further defined the functional roles of PA-X by comparing PA-X proteins from two related viruses - equine influenza (EIV) and canine influenza (CIV) H3...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2016.06.001

    authors： Feng KH,Sun M,Iketani S,Holmes EC,Parrish CR

    更新日期：2016-09-01 00:00:00

  • Evidence for replication of cauliflower mosaic virus DNA in plant nuclei.

    abstract：:Cellular organelles of cauliflower mosaic virus-infected turnip plants were isolated, incubated with 32P-labeled deoxyribonucleoside triphosphates and assayed for their ability to synthesize virus-specific DNA. Only nuclei were found to synthesize a labeled DNA product. This DNA migrated during agarose gel electrophor...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(82)90124-6

    authors： Ansa OA,Bowyer JW,Shepherd RJ

    更新日期：1982-08-01 00:00:00

  • Adenovirus E1A proteins are closely associated with chromatin in productively infected and transformed cells.

    abstract：:The adenovirus E1A 243R oncoprotein encodes a potent transcription-repression function within the N-terminal 80 amino acids. Our proposed model of E1A repression predicts that E1A interacts with important cellular proteins on chromatin. Consistent with this idea, we report here that E1A proteins from in vivo formaldeh...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2007.10.021

    authors： Green M,Panesar NK,Loewenstein PM

    更新日期：2008-02-05 00:00:00

  • Immunogenicity of peptides simulating a neutralization epitope of transmissible gastroenteritis virus.

    abstract：:Previously, an epitope recognized by a set of neutralizing monoclonal antibodies directed against the S protein of transmissible gastroenteritis has been identified. This neutralization epitope can be simulated by a single peptide combining residues 380 to 387 and 1176 to 1184 of the S protein; this combination peptid...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(91)90684-4

    authors： Posthumus WP,Lenstra JA,van Nieuwstadt AP,Schaaper WM,van der Zeijst BA,Meloen RH

    更新日期：1991-05-01 00:00:00

  • Early antibody responses map to non-protective, PCV2 capsid protein epitopes.

    abstract：:Porcine circovirus type 2 (PCV2) is an economically important cause of post-weaning multisystemic wasting syndrome (PMWS) in weanling piglets. Current commercial vaccines against PCV2 are highly effective. Yet, a recurring emergence of new genotypes in vaccinated herds necessitates a better understanding of protective...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2019.11.008

    authors： Ilha M,Nara P,Ramamoorthy S

    更新日期：2020-01-15 00:00:00

  • Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant.

    abstract：:Brain metastases occur commonly in the setting of a variety of human cancers. At present, such cases are invariably fatal and highlight a need for research on new therapies. We have developed a mouse brain tumor model utilizing the Harding-Passey melanoma cell line injected intracranially into C57Bl/6 mice. Tumors dev...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1995.1382

    authors： Randazzo BP,Kesari S,Gesser RM,Alsop D,Ford JC,Brown SM,Maclean A,Fraser NW

    更新日期：1995-08-01 00:00:00