The minute virus of mice exploits different endocytic pathways for cellular uptake.

abstract：:The envelope (E) protein of dengue virus (DENV) is composed of three domains (EDI, EDII, EDIII) and is the main target of neutralizing antibodies. Many monoclonal antibodies that bind EDIII strongly neutralize DENV. However in vitro studies indicate that anti-EDIII antibodies contribute little to the neutralizing pote...

journal_title：Virology

authors： Williams KL,Wahala WM,Orozco S,de Silva AM,Harris E

更新日期：2012-07-20 00:00:00

abstract：:The pr55gag polyprotein of HIV-1 plays a critical role in the formation of immature virus particles in the cell and during the budding process. We investigated the influence of amino acid substitutions in the p24CA- region of the gag polyprotein on the viral assembly process. Deletion of the amino acids 341-352 in the...

journal_title：Virology

authors： von Poblotzki A,Wagner R,Niedrig M,Wanner G,Wolf H,Modrow S

更新日期：1993-04-01 00:00:00

abstract：:Human papillomavirus type 16 E7 protein, expressed in Escherichia coli as fusion protein lac alpha peptide-E7 (lac-E7), was purified by electrophoresis and used to immunize rabbits to raise antisera. The anti-lac-E7 sera recognized another bacterially expressed fusion protein trpE-E7 by the Western blot method. The an...

journal_title：Virology

authors： Sato H,Watanabe S,Furuno A,Yoshiike K

更新日期：1989-05-01 00:00:00

abstract：:The HPV16 E7 oncoprotein and 17β-estradiol are important factors for the induction of premalignant lesions and cervical cancer. The study of these factors is crucial for a better understanding of cervical tumorigenesis. Here, we assessed the global gene expression profiles induced by the HPV16 E7 oncoprotein and/or 17...

journal_title：Virology

authors： Cortés-Malagón EM,Bonilla-Delgado J,Díaz-Chávez J,Hidalgo-Miranda A,Romero-Cordoba S,Uren A,Celik H,McCormick M,Munguía-Moreno JA,Ibarra-Sierra E,Escobar-Herrera J,Lambert PF,Mendoza-Villanueva D,Bermudez-Cruz RM,Gariglio P

更新日期：2013-12-01 00:00:00

abstract：:After intranasal inoculation, mouse hepatitis virus (MHV) gains entry into the central nervous system (CNS) via the olfactory and trigeminal nerves. Under the appropriate conditions, some mice develop clinically apparent demyelinating encephalomyelitis several weeks later, with virus always present in the spinal cord....

journal_title：Virology

authors： Perlman S,Jacobsen G,Olson AL,Afifi A

更新日期：1990-04-01 00:00:00

abstract：:We demonstrate that the AL2 gene of Cabbage leaf curl virus (CaLCuV) activates the CP promoter in mesophyll and acts to derepress the promoter in vascular tissue, similar to that observed for Tomato golden mosaic virus (TGMV). Binding studies indicate that sequences mediating repression and activation of the TGMV and ...

journal_title：Virology

authors： Lacatus G,Sunter G

更新日期：2008-06-20 00:00:00

abstract：:Lloviu virus (LLOV), a phylogenetically divergent filovirus, is the proposed etiologic agent of die-offs of Schreibers's long-fingered bats (Miniopterus schreibersii) in western Europe. Studies of LLOV remain limited because the infectious agent has not yet been isolated. Here, we generated a recombinant vesicular sto...

journal_title：Virology

authors： Ng M,Ndungo E,Jangra RK,Cai Y,Postnikova E,Radoshitzky SR,Dye JM,Ramírez de Arellano E,Negredo A,Palacios G,Kuhn JH,Chandran K

更新日期：2014-11-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) is used as a model to study gammaherpesvirus pathogenesis both in tissue culture systems and in vivo. We used a gene-trapping approach to get insight into cellular factors involved in MHV68 infection. By generating a library of gene-trapped CHO cells, we were able to isolate several ...

journal_title：Virology

authors： Jarousse N,Coscoy L

更新日期：2008-04-10 00:00:00

abstract：:HAV particles isolated from infected cells banded at buoyant densities of 1.42, 1.32, and 1.20 g/ml, and distinctive protein patterns were established by gel electrophoresis and reverse phase high performance liquid chromatography. The relatively higher amounts of p30 in particles with lower buoyant densities suggest ...

journal_title：Virology

authors： Gauss-Müller V,Lottspeich F,Deinhardt F

更新日期：1986-12-01 00:00:00

abstract：:We previously demonstrated that human parainfluenza virus type 2 (hPIV-2) induces RhoA activation, which promotes its growth. RhoA controls the equilibrium between globular and filamentous actin (F-actin). We found that F-actin formation is induced by wild type (wt) hPIV-2 infection, and that inhibition of F-actin for...

journal_title：Virology

authors： Ohta K,Matsumoto Y,Yumine N,Nishio M

更新日期：2018-11-01 00:00:00

abstract：:We have previously adapted an experimental system which supports autonomous replication of human papillomavirus-11 (HPV-11) genomic DNA in a human squamous carcinoma cell line (SCC-4) following electroporation of linearized viral DNA. This system allows evaluation of HPV-11 transcription in the context of replicating ...

journal_title：Virology

authors： Renaud KJ,Cowsert LM

更新日期：1996-06-01 00:00:00

abstract：:Human enteric adenovirus Ad41 is associated with children gastroenteritis. To infect gastrointestinal cells, the invading virus must be acid-stable and resistant to inactivation by bile salts and proteases. In addition, it has to cross the mucus barrier before it infects mucosa cells. We show that Ad41 infectivity is ...

journal_title：Virology

authors： Favier AL,Burmeister WP,Chroboczek J

更新日期：2004-04-25 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection can be inhibited by small molecules that target the CCR5 coreceptor. Here, we describe some properties of clonal viruses resistant to one such inhibitor, SCH-D, using both chimeric, infectious molecular clones and Env-pseudotypes. Studies using combinations of CCR5...

journal_title：Virology

authors： Pugach P,Marozsan AJ,Ketas TJ,Landes EL,Moore JP,Kuhmann SE

更新日期：2007-04-25 00:00:00

abstract：:This paper reports the molecular cloning of a rearranged c-myc region from the FT-1 cell line, which was derived from a spontaneous feline T-cell leukemia carrying the feline leukemia virus (FeLV). An abnormal c-myc EcoRI fragment of about 18 kilobases, detected by Southern blotting, was molecularly cloned from the DN...

journal_title：Virology

authors： Miura T,Shibuya M,Tsujimoto H,Fukasawa M,Hayami M

更新日期：1989-04-01 00:00:00

abstract：:Processing of the transmembrane glycoprotein (GP) of Marburg virus involved the conversion of an endo H-sensitive, ER-specific form into an endo H-resistant, Golgi-specific precursor that was cleaved into GP(1) and GP(2). Cleavage was mediated by furin or another subtilisin-like endoprotease with similar substrate spe...

journal_title：Virology

authors： Volchkov VE,Volchkova VA,Ströher U,Becker S,Dolnik O,Cieplik M,Garten W,Klenk HD,Feldmann H

更新日期：2000-03-01 00:00:00

abstract：:Very fast sedimenting DNA (VFS DNA) of T4 phage, which is formed by infection with a mutant in gene 49, was examined by electron microscopy after mild treatment with DNase I. It showed Y-shaped, branched strands in addition to linear strands. Each branch contained a single-stranded interruption about 60 nucleotides lo...

journal_title：Virology

authors： Minagawa T,Murakami A,Ryo Y,Yamagishi H

更新日期：1983-04-15 00:00:00

abstract：:A full-length cDNA of cucurbit aphid-borne yellows virus (CABYV) has been constructed and expressed either as an in vitro transcript, under control of a bacteriophage T7 RNA polymerase promoter, or in vivo, under control of the cauliflower mosaic virus 35S promoter in an agroinfection vector. The biological activity o...

journal_title：Virology

authors： Prüfer D,Wipf-Scheibel C,Richards K,Guilley H,Lecoq H,Jonard G

更新日期：1995-12-01 00:00:00

abstract：:Nanogram amounts of the proinflammatory cytokine interleukin-1alpha (IL-1alpha) were detected in uninfected cultures of human corneal epithelial cells (HCEC). Although HSV-1 replicated >10(4)-fold in these cells and caused extensive cytopathic effects, virus infection was not accompanied by significant extracellular r...

journal_title：Virology

authors： Tran MT,Dean DA,Lausch RN,Oakes JE

更新日期：1998-04-25 00:00:00

abstract：:Genomic and messenger RNAs of a Zaire strain of Ebola virus were cloned, and inserts specific for the nucleoprotein gene were isolated and sequenced. The nucleoprotein gene is located proximal to the 3' end of the genome and is preceeded by a putative leader sequence. The gene begins with the transcriptional start sit...

journal_title：Virology

authors： Sanchez A,Kiley MP,Holloway BP,McCormick JB,Auperin DD

更新日期：1989-05-01 00:00:00

abstract：:Three different protein molecules copurify with T4 tail tubes after the tubes are released from the baseplate by guanidine hydrochloride treatment. These tube-associated proteins (TAPs) are the products of genes 29, 48, and 54. To further investigate the structural roles that these proteins may play in T4 tail assembl...

journal_title：Virology

authors： Ishimoto LK,Ishimoto KS,Cascino A,Cipollaro M,Eiserling FA

更新日期：1988-05-01 00:00:00

abstract：:Experiments were undertaken to determine if the sera of avian sarcoma virus-infected 15I5 X 7(2) chickens exhibit antibody reactivity for species of endogenous retroviral envelope glycoprotein expressed in 15I5 X 7(2) fibroblasts. Two viruses were used for infection of the 15I5 X 7(2) chickens, Pr-A and cl. 85; the en...

journal_title：Virology

authors： Halpern MS,Deery DT,Flores LJ,Fujita DJ,Mason WS

更新日期：1983-01-30 00:00:00

abstract：:Within the family of Poxviridae, the entomopoxviruses are the most distant relatives of the more well-known and intensively studied orthopoxviruses (vaccinia and variola). The growth of the entomopoxvirus from Amsacta moorei (AmEPV) has been characterized in cell culture and compared to that of vaccinia virus (VV), th...

journal_title：Virology

authors： Winter J,Hall RL,Moyer RW

更新日期：1995-08-20 00:00:00

abstract：:This report shows that (S)CARNA 5, the satellite of cucumber mosaic virus (CMV) strain S, directs the synthesis of two small proteins in a wheat germ cell-free translation system. The two proteins are produced by the translation of both (S)CARNA 5 purified from CMV virions and the (+) strand purified from double-stran...

journal_title：Virology

authors： Avila-Rincon MJ,Collmer CW,Kaper JM

更新日期：1986-07-30 00:00:00

abstract：:The flavivirus nonstructural protein NS1 has been implicated in viral RNA replication, although its precise role has not been identified. In its native state NS1 exists as a heat labile homodimer that is thought to be required for NS1 function and secretion. However, we have recently identified a cDNA clone of KUN vir...

journal_title：Virology

authors： Hall RA,Khromykh AA,Mackenzie JM,Scherret JH,Khromykh TI,Mackenzie JS

更新日期：1999-11-10 00:00:00

abstract：:In a previous paper (G. Winkler, V. B. Randolph, G. R. Cleaves, T. E. Ryan, and V. Stollar, 1988, Virology 162, 187-196) we showed that the newly synthesized dengue-2 virus nonstructural protein, NS1, exists briefly as a monomer and then undergoes dimerization. We demonstrate here that the dimerization of NS1 is assoc...

journal_title：Virology

authors： Winkler G,Maxwell SE,Ruemmler C,Stollar V

更新日期：1989-07-01 00:00:00

abstract：:The RNA dependent RNA polymerase of Sendai virus consists of a complex of the large (L) and phosphoprotein (P) subunits where L is thought to be responsible for all the catalytic activities necessary for viral RNA synthesis. We previously showed that the L protein forms an oligomer [Smallwood, S., Cevik, B., Moyer, S....

journal_title：Virology

authors： Cevik B,Smallwood S,Moyer SA

更新日期：2007-06-20 00:00:00

abstract：:In mid-January 2016, an outbreak of H7N8 high-pathogenicity avian influenza virus (HPAIV) in commercial turkeys occurred in Indiana. Surveillance within the 10km control zone identified H7N8 low-pathogenicity avian influenza virus (LPAIV) in nine surrounding turkey flocks but no other HPAIV-affected premises. We seque...

journal_title：Virology

authors： Lee DH,Torchetti MK,Killian ML,Swayne DE

更新日期：2017-07-01 00:00:00

abstract：:Red clover necrotic mosaic virus (RCNMV) encodes N-terminally overlapping proteins of 27 and 88 kDa (p27 and p88) known to be required for replication. Green fluorescent protein (GFP) fusions were used to visualize the location of p27 and p88 within Nicotiana benthamiana cells. GFP:p27 fusions localized to the endopla...

journal_title：Virology

authors： Turner KA,Sit TL,Callaway AS,Allen NS,Lommel SA

更新日期：2004-03-15 00:00:00

abstract：:The OC43 strain of human coronavirus (HCoV-OC43) is an ubiquitous respiratory tract pathogen possessing neurotropic capacities. Coronavirus structural envelope (E) protein possesses specific motifs involved in protein-protein interaction or in homo-oligomeric ion channel formation, which are known to play various role...

journal_title：Virology

authors： Stodola JK,Dubois G,Le Coupanec A,Desforges M,Talbot PJ

更新日期：2018-02-01 00:00:00

abstract：:VP5, a 5'-terminal, small open reading frame in segment A of the aquatic birnavirus (infectious pancreatic necrosis virus, IPNV) genome, encodes a 17-kDa nonstructural protein. We previously reported apoptosis induced by IPNV in a fish cell line. In the present study, we cloned and identified VP5 and tested its functi...

journal_title：Virology

authors： Hong JR,Gong HY,Wu JL

更新日期：2002-04-10 00:00:00