CCAAT/enhancer binding protein beta binds to and activates the P670 promoter of human papillomavirus type 16.

abstract：:HIV CRF07 B'/C is a strain circulating mainly in northwest region of China. The gp41 region of CRF07 is derived from a clade C virus. In order to compare the difference of CRF07 gp41 with that of typical clade B virus, we solved the crystal structure of the core region of CRF07 gp41. Compared with clade B gp41, CRF07 ...

journal_title：Virology

authors： Du J,Xue H,Ma J,Liu F,Zhou J,Shao Y,Qiao W,Liu X

更新日期：2013-11-01 00:00:00

abstract：:RNA copies, synthesized in vitro, of the virulent satellite (RNA C) of turnip crinkle virus (TCV) infect plants when coinoculated with helper virus RNA. RNA C is a small linear RNA of about 355 bases which intensifies TCV symptoms in infected plants. Full-length cDNA copies of the satellite were inserted in an express...

journal_title：Virology

authors： Simon AE,Howell SH

更新日期：1987-01-01 00:00:00

abstract：:A series of nucleotide substitutions (G46----C; C47----A; C315----U; U317----C) were introduced into the virulence modulating region of the intermediate strain of potato spindle tuber viroid (PSTVd) in order to examine their effect upon viroid infectivity and pathogenicity with the presence of all four mutations resul...

journal_title：Virology

authors： Hammond RW

更新日期：1992-04-01 00:00:00

abstract：:To begin to map functional domains of the Sendai P-L RNA polymerase complex we wanted to characterize the P binding site on the Sendai L protein. Analysis of in vitro and in vivo P-L polymerase complex formation with carboxyl-truncations of the L protein showed that the N-terminal half of the protein was required. Sit...

journal_title：Virology

authors： Chandrika R,Horikami SM,Smallwood S,Moyer SA

更新日期：1995-11-10 00:00:00

abstract：:There is growing evidence that the receptor-binding characteristics of influenza viruses are affected by the host-dependent glycosylation of viral hemagglutinin (HA). To better understand these effects, we propagated two variants of the human influenza virus USSR/90/77 (which differed by the mutation Asn131 reversible...

journal_title：Virology

authors： Gambaryan AS,Marinina VP,Tuzikov AB,Bovin NV,Rudneva IA,Sinitsyn BV,Shilov AA,Matrosovich MN

更新日期：1998-08-01 00:00:00

abstract：:An Autographa californica nuclear polyhedrosis virus gene encoding an occlusion-derived virus (ODV) envelope protein of 56 kDa was identified and sequenced. Transcription initiates from a conserved baculovirus late motif (ATAAG) with transcripts detected from 16 through 72 hr p.i. The protein is detected in infected c...

journal_title：Virology

authors： Braunagel SC,Elton DM,Ma H,Summers MD

更新日期：1996-03-01 00:00:00

abstract：:The 24,000-molecular-weight major internal protein (p24) and the 15,000-molecular-weight nucleic acid binding protein (p15) of human T-cell leukemia virus type II (HTLV-II) were subjected to amino acid composition and amino-terminal amino acid sequence analysis. A comparison of amino acid composition of p24 and p15 of...

journal_title：Virology

authors： Devare SG,Kim Y,Fox JL,Getchell J,Cabradilla C,Kalyanaraman VS

更新日期：1985-04-15 00:00:00

abstract：:Vaccinia topoisomerase provides a model system for structure-function analysis of the type IB topoisomerase family. Here we performed an alanine scan of eight positions in the beta4 and beta5 strands of the N-terminal domain (Leu57, Ile58, Phe59, Val60, Gly61, Ser62, Gln69 and Gly73) and eight positions in the alpha8-...

journal_title：Virology

authors： Tian L,Shuman S

更新日期：2007-03-15 00:00:00

abstract：:This study evaluates the role of antibody as an indicator of immunity to ocular challenge with herpes simplex virus (HSV). Two genotypes of mice, BALB/c or BALB/c with mu-chain knockout (muK/O; which lack functional B cells), were immunized systemically either with nonvirulent infectious virus or with a eukaryotic exp...

journal_title：Virology

authors： Daheshia M,Deshpande S,Chun S,Kuklin NA,Rouse BT

更新日期：1999-04-25 00:00:00

abstract：:The 3' untranslated regions (UTRs) of many plant viral RNAs contain cap-independent translation elements (3' CITEs). Among the 3' CITEs, the Barley yellow dwarf virus (BYDV)-like translation elements (BTEs) form a structurally variable and widely distributed group. Viruses in three genera were known to harbor 3' BTEs,...

journal_title：Virology

authors： Wang Z,Kraft JJ,Hui AY,Miller WA

更新日期：2010-06-20 00:00:00

abstract：:The red clover necrotic mosaic dianthovirus capsid protein is expressed in vivo from a subgenomic RNA (sgRNA) identical to the 3'-terminal 1.5 kb of RNA-1. The 5' leader sequence of the capsid protein sgRNA is 62 nucleotides, contains a 14-nucleotide putative promoter sequence homologous to the RNA-1 5' terminus, and ...

journal_title：Virology

authors： Zavriev SK,Hickey CM,Lommel SA

更新日期：1996-02-15 00:00:00

abstract：:The Ns strain of Cucumber mosaic virus (CMV) induces hypersensitive response (HR) on Nicotiana tabacum cv. Xanthi-nc and on Nicotiana glutinosa. The genetic determinant of the HR induction was localized earlier to amino acid 461 of the 1a protein. The 3D structure of the 1a protein is still unknown and building a homo...

journal_title：Virology

authors： Salánki K,Gellért A,Náray-Szabó G,Balázs E

更新日期：2007-02-05 00:00:00

abstract：:The retroviral cyclin protein (rv-cyclin) of walleye dermal sarcoma virus contains two known functional domains, a cyclin box motif and a carboxy terminal transcription activation domain (AD). The AD contacts TATA-binding protein-associated factor 9 (TAF9), and this action is necessary for both positive and negative r...

journal_title：Virology

authors： Quackenbush SL,Linton A,Brewster CD,Rovnak J

更新日期：2009-03-30 00:00:00

abstract：:Rice yellow mottle virus (RYMV) is icosahedral in morphology and known to swell in vitro, but the biological function of swollen particles remains unknown. Anion-exchange chromatography was used to identify three markedly stable forms of RYMV particles from infected plants: (1) an unstable swollen form lacking Ca2+ an...

journal_title：Virology

authors： Brugidou C,Opalka N,Yeager M,Beachy RN,Fauquet C

更新日期：2002-05-25 00:00:00

abstract：:The interaction of reovirus with the cytoskeleton was investigated. The soluble components of infected cells were extracted with the nonionic detergent NP-40 in a physiological buffer, and a cytoskeletal extract was prepared from the detergent-insoluble fraction. We observed a selective association of viral-specified ...

journal_title：Virology

authors： Mora M,Partin K,Bhatia M,Partin J,Carter C

更新日期：1987-08-01 00:00:00

abstract：:The (guanine-N7)-methyltransferase domain of the vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit D1(498-844) bound to a stimulatory subunit D12. To identify structural elements of the 287-amino-acid D12 subunit that participate in binding and activation of the catalytic subunit, we ...

journal_title：Virology

authors： Saha N,Shuman S

更新日期：2001-08-15 00:00:00

abstract：:Cellular organelles of cauliflower mosaic virus-infected turnip plants were isolated, incubated with 32P-labeled deoxyribonucleoside triphosphates and assayed for their ability to synthesize virus-specific DNA. Only nuclei were found to synthesize a labeled DNA product. This DNA migrated during agarose gel electrophor...

journal_title：Virology

authors： Ansa OA,Bowyer JW,Shepherd RJ

更新日期：1982-08-01 00:00:00

abstract：:The APOBEC3 enzyme family are host restriction factors that induce mutagenesis of HIV-1 proviral genomes through the deamination of cytosine to form uracil in nascent single-stranded (-)DNA. HIV-1 suppresses APOBEC3 activity through the HIV-1 protein Vif that induces APOBEC3 degradation. Here we compared two common po...

journal_title：Virology

authors： Mohammadzadeh N,Follack TB,Love RP,Stewart K,Sanche S,Chelico L

更新日期：2019-01-15 00:00:00

abstract：:To identify the potential RNA inhibitors of HCV polymerase, we have isolated high-affinity RNA ligands specific to hepatitis C virus (HCV) NS5B protein from a combinatorial RNA library using the Systematic Evolution of Ligands by EXponential enrichment (SELEX) procedure. Thirty-seven selected ligands were classified i...

journal_title：Virology

authors： Vo NV,Oh JW,Lai MM

更新日期：2003-03-15 00:00:00

abstract：:In order to define factors involved in very late Autographa californica nucleopolyhedrovirus (AcMNPV) gene function, random mutagenesis of a baculovirus recombinant (AcUW1.lacZ) by 5'-bromodeoxyuridine treatment was performed. Five viruses were selected with deficiencies in very late gene expression. These were charac...

journal_title：Virology

authors： Merrington CL,Kitts PA,King LA,Possee RD

更新日期：1996-03-01 00:00:00

abstract：:The molecular cloning of the DNA provirus of Mason-Pfizer monkey virus (M-PMV) is described. Fourteen independent clones of integrated M-PMV proviruses were isolated from a human embryo kidney cell line that had been previously derived from a single cell clone infected with M-PMV. Characterization of these clones for ...

journal_title：Virology

authors： Barker CS,Pickel J,Tainsky M,Hunter E

更新日期：1986-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) core protein constitutes a viral nucleocapsid and may possess multiple functions. In this study, we demonstrated the homotypic interaction and multimerization of HCV core protein in vitro and in vivo. By using a yeast two-hybrid system, we showed that the amino-terminal hydrophilic portion (ami...

journal_title：Virology

authors： Matsumoto M,Hwang SB,Jeng KS,Zhu N,Lai MM

更新日期：1996-04-01 00:00:00

abstract：:An in-frame gag gene mutant of human immunodeficiency virus type 1, which carries two amino acid substitutions in the center of the p24 coding region, was constructed in vitro, and its replication properties in several cell lines were examined. In CD4-negative SW480 cells transfected with the mutant clone, synthesis a...

journal_title：Virology

authors： Sakuragi J,Sakai H,Kawamura M,Tokunaga K,Ueda S,Adachi A

更新日期：1995-09-10 00:00:00

abstract：:A mutant strain of polyoma virus encoding a truncated middle T protein has been studied for its ability to replicate and induce tumors following inoculation into newborn mice. Virus replication in the acute period prior to expected onset of tumors as well as persistence of virus in older animals were followed. The mut...

journal_title：Virology

authors： Freund R,Sotnikov A,Bronson RT,Benjamin TL

更新日期：1992-12-01 00:00:00

abstract：:HTLV-I infection is characterized by low viremia and restricted viral expression. While the mechanisms regulating viral latency are poorly understood, it is believed that interactions between viral and host cellular factor(s) are involved. Several lines of evidence indicate that HTLV-I provirus may be methylated in pr...

journal_title：Virology

authors： Saggioro D,Forino M,Chieco-Bianchi L

更新日期：1991-05-01 00:00:00

abstract：:The longest open reading frame of turnip yellow mosaic virus genomic RNA (ORF-206) encodes a 206-kDa nonstructural protein. The most prominent in vitro translation products of ORF-206 are the full-length p206 and a shorter N-coterminal 150-kDa protein. We have confirmed these assignments by immunoprecipitation of in v...

journal_title：Virology

authors： Bransom KL,Weiland JJ,Dreher TW

更新日期：1991-09-01 00:00:00

abstract：:Equid herpesvirus-1 (EHV-1) outbreaks continue despite widely used vaccination. We demonstrated previously that an ORF1/ORF71 gene deletion mutant of the EHV-1 strain Ab4 (Ab4ΔORF1/71) is less virulent than its parent Ab4 virus. Here, we describe the Ab4 challenge infection evaluating protection induced by the Ab4ΔORF...

journal_title：Virology

authors： Perkins G,Babasyan S,Stout AE,Freer H,Rollins A,Wimer CL,Wagner B

更新日期：2019-05-01 00:00:00

abstract：:The movement protein (MP) of cauliflower mosaic virus (CaMV) is a multifunctional protein that potentiates the cell-to-cell and long distance movement of the virus. Functional domains in the CaMV MP were determined by analyzing deletions in green fluorescent protein (GFP)-MP fusions transfected into Arabidopsis thalia...

journal_title：Virology

authors： Huang Z,Han Y,Howell SH

更新日期：2000-05-25 00:00:00

abstract：:Human enteric adenovirus Ad41 is associated with children gastroenteritis. To infect gastrointestinal cells, the invading virus must be acid-stable and resistant to inactivation by bile salts and proteases. In addition, it has to cross the mucus barrier before it infects mucosa cells. We show that Ad41 infectivity is ...

journal_title：Virology

authors： Favier AL,Burmeister WP,Chroboczek J

更新日期：2004-04-25 00:00:00

abstract：:We have previously shown that the late promoter of the human papovavirus BK (prototype) is contained within the three 68-bp repeats and a 66-bp region to the late side of the repeats which together constitute the early promoter enhancer. We have now carried out unidirectional deletion and linker scan analyses of these...

journal_title：Virology

authors： Cassill JA,Deyerle KL,Subramani S

更新日期：1989-03-01 00:00:00