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Mannose metabolism: more than meets the eye.

Abstract：

:Mannose is a simple sugar with a complex life. It is a welcome therapy for genetic and acquired human diseases, but it kills honeybees and blinds baby mice. It could cause diabetic complications. Mannose chemistry, metabolism, and metabolomics in cells, tissues and mammals can help explain these multiple systemic effects. Mannose has good, bad or ugly outcomes depending on its steady state levels and metabolic flux. This review describes the role of mannose at cellular level and its impact on organisms.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Sharma V,Ichikawa M,Freeze HH

doi

10.1016/j.bbrc.2014.06.021

subject

Has Abstract

pub_date

2014-10-17 00:00:00

pages

220-8

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(14)01095-X

journal_volume

453

pub_type

杂志文章,评审

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