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Isolation of tumor disturbing factor on the proliferation of tumor cells in human serum.

Abstract：

:The classified sediment with ethanol from sera of nude mice and humans showed a disturbing effect on L1210 cells in vitro and a lifesaving effect on L1210 cell-bearing mice in vivo. This factor was purified more than 2300-fold to a specific activity of approximately 1 X 10(5) U/mg by ethanol classified precipitation, Sephadex G-200 gel filtration, DEAE cellulose ion exchange chromatography with Nacl and pH gradient aqueous solution, and preparative polyacrylamide gel electrophoresis.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Sakagami Y,Manabe H

doi

10.1016/0006-291x(84)91285-3

subject

Has Abstract

pub_date

1984-04-30 00:00:00

pages

520-6

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)91285-3

journal_volume

120

pub_type

杂志文章

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