Association and dissociation of the calcium-binding domains of calpain by Ca2+.

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Biochemical and biophysical research communications

authors： Xiao F,Hu Q,Zeng M,Guan L,Liu X,Yang Y,Zhong C

更新日期：2012-04-13 00:00:00

abstract：:Signal transduction by transforming growth factor-beta (TGF-beta) involves the formation of a heteromeric complex of two transmembrane serine/threonine kinase receptors, type I (T beta R-I) and type II (T beta R-II). In the region preceeding the kinase domain of T beta R-I there is a glycine- and serine-rich sequence,...

journal_title：Biochemical and biophysical research communications

authors： Franzén P,Heldin CH,Miyazono K

更新日期：1995-02-15 00:00:00

abstract：:COMPARE computer program suggested that benzamide riboside, BR, 3-(1-deoxy-beta-D-ribofuranosyl)benzamide, should have a similar mechanism of action as that of tiazofurin, an inhibitor of IMP dehydrogenase (IMPDH). This hypothesis was tested in K562 cells in culture. BR was cytotoxic to K562 cells with an IC50 of 2 mi...

journal_title：Biochemical and biophysical research communications

authors： Jayaram HN,Gharehbaghi K,Jayaram NH,Rieser J,Krohn K,Paull KD

更新日期：1992-08-14 00:00:00

abstract：:We have characterized the hydrodynamic behavior of nucleosome arrays in which the N- and C-terminal "tails" of the histone H2A-H2B and H3-H4 domains have been selectively removed by digestion with immobilized trypsin. The sedimentation coefficient of the polynucleosome fibers lacking the histone H2A-H2B tails exhibite...

journal_title：Biochemical and biophysical research communications

authors： Moore SC,Ausió J

更新日期：1997-01-03 00:00:00

abstract：:Cyclosporine A (CSA) is a widely used immunosuppressant drug known to commonly cause cardio and nephrotoxicity. A study looking at the sex specificity of the cardiotoxicity of CSA revealed that sexual dimorphism existed when looking at the electrocardiographs and left ventricles of CSA-treated rats. We hypothesized th...

journal_title：Biochemical and biophysical research communications

authors： El-Bassossy HM,Eid BG

更新日期：2018-01-01 00:00:00

abstract：:A few examples of translational activation by antisense small noncoding RNAs (sRNAs) have already been discovered in prokaryotic cells, and all of them are through a sense-antisense interaction at the 5'-untranslated region (5'-UTR) of target mRNAs. Here, we report a novel phenomenon of translational activation of pro...

journal_title：Biochemical and biophysical research communications

authors： Hayashi G,Hong C,Hagihara M,Nakatani K

更新日期：2012-12-07 00:00:00

abstract：:A novel protein kinase activity was characterized from the cytosolic fraction of isolated rabbit gastric glands. The kinase phosphorylated a major 33,000 Da endogenous protein (pp33) and was stimulated by Zn2+ and Mn2+ with Kact of 1.0 and 7.5 mM, respectively. Mg2+ and Ca2+ failed to stimulate any pp33 kinase activit...

journal_title：Biochemical and biophysical research communications

authors： Goldenring JR,Oddsdottir M,Modlin IM

更新日期：1987-01-30 00:00:00

abstract：:The aim of the study was to determine the expression profiles of message RNAs and long non-coding RNAs in CD4+T cells of asthmatic patients and to explore the clinical value and biological function. Expression profiles in CD4+T cells of asthmatic patients and healthy controls were analyzed by microarray. We found 2725...

journal_title：Biochemical and biophysical research communications

authors： Qi X,Chen H,Huang Z,Fu B,Wang Y,Xie J,Zhao J,Cao Y,Xiong W

更新日期：2018-09-10 00:00:00

abstract：:Alkaline elastase YaB, produced by alkalophilic Bacillus YaB, is an extracellular serine protease having 55% homology to subtilisin BPN' and thus could be called subtilisin YaB. It is synthesized as a 378-amino acid preproenzyme and secreted into the culture medium as a 265-amino acid mature protease. To examine if th...

journal_title：Biochemical and biophysical research communications

authors： Chang YC,Kadokura H,Yoda K,Yamasaki M

更新日期：1996-02-15 00:00:00

abstract：:A series of amino acid-derived sulfonate salts have been synthesized. They were found to inactivate efficiently and selectively human leukocyte elastase. The sulfonate salts of the methyl esters of L-norleucine, L-norvaline and L-valine were the most potent. The enzyme is inactivated irreversibly with concomitant rele...

journal_title：Biochemical and biophysical research communications

authors： Groutas WC,Brubaker MJ,Zandler ME,Stanga MA,Huang TL,Castrisos JC,Crowley JP

更新日期：1985-04-16 00:00:00

abstract：:Insulin-like growth factor-II (IGF-II) is a potent mitogen for cells in culture. The H19 gene is a developmentally regulated gene with putative tumor suppressor activity, and loss of H19 expression may be involved in tumorigenesis. The H19 gene is closely linked to the human IGF-II gene (IGF2) on chromosome 11p15.5 an...

journal_title：Biochemical and biophysical research communications

authors： Kiess W,Paquette J,Koepf G,Wolf E,Deal C

更新日期：1999-02-16 00:00:00

abstract：:The in vitro effects of various steroid and thyroid hormones on synthesis of rat atrial natriuretic peptide (rANP) were studied using new-born rat atrial myocytes in culture. Dexamethasone, testosterone and triiodothyronine markedly stimulated both synthesis and secretion of immunoreactive (IR)-rANP with the same peak...

journal_title：Biochemical and biophysical research communications

authors： Matsubara H,Hirata Y,Yoshimi H,Takata S,Takagi Y,Iida T,Yamane Y,Umeda Y,Nishikawa M,Inada M

更新日期：1987-05-29 00:00:00

abstract：:The yeast transcriptional regulator Hap1 promotes both transcriptional activation and repression. Previous studies have shown that Hap1 binds to the promoter of its own gene and represses its transcription. In this report, we identified the DNA site that allows Hap1-binding with high affinity. This Hap1-binding site c...

journal_title：Biochemical and biophysical research communications

authors： Xin X,Lan C,Lee HC,Zhang L

更新日期：2007-10-12 00:00:00

abstract：:The aim of this study was to investigate hormonal factors responsible for the huge increase in PRL receptors on the day of estrus in the rat mammary gland. For this purpose, ovariectomized rats were primed with E2 so as to reach a physiological serum concentration of E2 (21.5 +/- 1.2 pg/ml) and high PRL serum values (...

journal_title：Biochemical and biophysical research communications

authors： Guillaumot P,Sabbagh I,Bertrand J,Cohen H

更新日期：1986-03-28 00:00:00

abstract：:Incorporation of [14C]serine into phosphatidylserine by the base exchange reaction in Ehrlich ascites tumor cells is inhibited by 30% by glucose and by 60% by 2-deoxyglucose (10 mM each). The inhibition by thapsigargin (0.2 microM) amounts to 80%. This inhibition is interpreted as being due to depletion of calcium sto...

journal_title：Biochemical and biophysical research communications

authors： Rakowska M,Wojtczak L

更新日期：1995-02-06 00:00:00

abstract：:The intracellular parasitic protist Trypanosoma cruzi is the causative agent of Chagas disease in Latin America. In general, pyrimidine nucleotides are supplied by both de novo biosynthesis and salvage pathways. While epimastigotes-an insect form-possess both activities, amastigotes-an intracellular replicating form o...

journal_title：Biochemical and biophysical research communications

authors： Hashimoto M,Morales J,Fukai Y,Suzuki S,Takamiya S,Tsubouchi A,Inoue S,Inoue M,Kita K,Harada S,Tanaka A,Aoki T,Nara T

更新日期：2012-01-20 00:00:00

abstract：:The nuclear-mitochondrial stringent response was examined in isonuclear rho+, 21S rRNA-containing rho-, and rho o strains of S. cerevisiae. By 30 min after nutritional downshift, nuclear rDNA transcription falls to 15% of control levels congruently in all strains, as assayed via whole-cell RNA or by hybrid selection o...

journal_title：Biochemical and biophysical research communications

authors： McEntee CM,Cantwell R,Thomas LC,Hudson AP

更新日期：1989-10-16 00:00:00

abstract：:A model for the degradation of xylose and ethanol production by Klebsiella planticola is proposed and compared with the exponential and Michaelis-Menten approaches. This model is based on the energy system diagrams and it is a simplified version of a previous model developed for the glucose and ethanol kinetics of the...

journal_title：Biochemical and biophysical research communications

authors： Bastianoni S,Gastaldelli A,Bonechi C,Mocenni C,Rossi C

更新日期：1996-10-03 00:00:00

abstract：:Maximal stimulation of inositol 1,4,5 trisphosphate (IP3) production by epinephrine and carbachol in rat parotid cell aggregates is additive when the two agents are employed simultaneously. The additive response proceeds through both the alpha 1-adrenergic and muscarinic-cholinergic signal transduction pathways. It is...

journal_title：Biochemical and biophysical research communications

authors： Kowatch MA,Roth GS

更新日期：1991-05-15 00:00:00

abstract：:The role of the cytoplasmic domain of human Fc gamma RII in cellular activation was studied by transfecting P815 cells with different isoforms or deletion mutants of this receptor and then assaying protein tyrosine phosphorylation after crosslinking with anti-CD32 monoclonal antibodies. Fc gamma RIIa, but not Fc gamma...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Pudiak D,Looney RJ

更新日期：1994-06-15 00:00:00

abstract：:REV-ERBα is a nuclear heme receptor, transcriptional repressor and critical component of the molecular clock that drives daily rhythms of metabolism. Evidence reveals that REV-ERBα also plays an important regulatory role in clock-dependent lung physiology and inflammatory responses. We hypothesize that cigarette smoke...

journal_title：Biochemical and biophysical research communications

authors： Sundar IK,Rashid K,Sellix MT,Rahman I

更新日期：2017-12-02 00:00:00

abstract：INTRODUCTION:SIRT2 is a NAD(+)-dependent deacetylases and associated with numerous processes such as infection, carcinogenesis, DNA damage and cell cycle regulation. However, the role of SIRT2 in inflammatory process in macrophage remains unclear. MATERIALS AND METHODS:In the present study, we have evaluated the regul...

journal_title：Biochemical and biophysical research communications

authors： Lee AS,Jung YJ,Kim D,Nguyen-Thanh T,Kang KP,Lee S,Park SK,Kim W

更新日期：2014-08-08 00:00:00

abstract：:Gallbladder carcinoma (GBC), an aggressive and mostly lethal malignancy, is known to be resistant to a number of drug stimuli. Here, we demonstrated that arsenic trioxide inhibited the proliferation of gallbladder carcinoma in vivo and in vitro as well as the transcription of cell cycle-related protein Cyclin D1. And,...

journal_title：Biochemical and biophysical research communications

authors： Ai Z,Lu W,Ton S,Liu H,Sou T,Shen Z,Qin X

更新日期：2007-08-31 00:00:00

abstract：:BST2 is an antiviral factor that inhibits the release of enveloped virus at the plasma membrane via an unusual topology in which its N-terminal is in the cytosol while its C-terminal is anchored by glycophosphatidylinositol (GPI). BST2-deficient cells showed substantially higher release of virions than wild type cells...

journal_title：Biochemical and biophysical research communications

authors： Yi E,Oh J,Kang HR,Song MJ,Park SH

更新日期：2019-02-05 00:00:00

abstract：:We investigated the expression of myocilin in the optic nerve head of porcine eyes by Western blotting and immunohistochemical staining. Myocilin was localized in the nucleus, centrosome, glial filament, mitochondria, and some parts of the cell membranes of the astrocytes. Myocilin was also detected at the edge-feet p...

journal_title：Biochemical and biophysical research communications

authors： Noda S,Mashima Y,Obazawa M,Kubota R,Oguchi Y,Kudoh J,Minoshima S,Shimizu N

更新日期：2000-10-05 00:00:00

abstract：:IL-13 mediates its effects through a complex receptor system including IL-4Ralpha and a functional IL-13Ralpha1. IL-13 has been reported to have no effects on mouse B cells due to a lack of receptor expression. However, on human B cells a functional IL-13Ralpha1 has been described. Here, we identified the rat IL-13Ral...

journal_title：Biochemical and biophysical research communications

authors： Pierrot C,Beniguel L,Bègue A,Khalife J

更新日期：2001-10-05 00:00:00

abstract：:Osterix (Osx) has been shown to be an osteoblast-specific transcription factor for bone formation. Recently, it has been reported that Osx is significantly expressed in the mouse olfactory bulb, proving that Osx may play a role in olfactory bulb development, as well as bone development. Here, we studied morphological ...

journal_title：Biochemical and biophysical research communications

authors： Park JS,Park GI,Kim JE

更新日期：2016-09-09 00:00:00

abstract：:Phosphoglucose isomerase (PGI) is a well-characterized ubiquitous enzyme involved in the glycolytic pathway. It catalyzes the reversible isomerization of D-glucopyranose-6-phosphate and D-fructofuranose-6-phosphate and is present in all living cells. However, there is interspecies variation at the level of the primary...

journal_title：Biochemical and biophysical research communications

authors： Mathur D,Ahsan Z,Tiwari M,Garg LC

更新日期：2005-11-18 00:00:00

abstract：:The contribution of four transport pathways to Li+ influx in human, chicken and eel erythrocytes was studied. All pathways were measured simultaneously in each kind of blood sample to avoid possible temporal variations in transport parameters. We found that: 1) Li+ influx via Na(+)-K+ pump increased 2-3 fold in the or...

journal_title：Biochemical and biophysical research communications

authors： Romano L,Battaglia M,Cordì R,Rinaldi C,Leucci S,Amato A

更新日期：1995-05-05 00:00:00

abstract：:Our previous studies have shown that the liver from Naked Mole Rats (NMRs), a long-lived rodent, has increased proteasome activity and lower levels of protein ubiquitination compared to mice. This suggests that protein quality control might play a role in assuring species longevity. To determine whether enhanced prote...

journal_title：Biochemical and biophysical research communications

authors： Pride H,Yu Z,Sunchu B,Mochnick J,Coles A,Zhang Y,Buffenstein R,Hornsby PJ,Austad SN,Pérez VI

更新日期：2015-02-20 00:00:00