当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Inhibition by glucose and deoxyglucose of phosphatidylserine synthesis in Ehrlich ascites tumor cells: a possible relation to the Crabtree effect and depletion of endoplasmic reticulum Ca2+ stores.

Inhibition by glucose and deoxyglucose of phosphatidylserine synthesis in Ehrlich ascites tumor cells: a possible relation to the Crabtree effect and depletion of endoplasmic reticulum Ca2+ stores.

Abstract：

:Incorporation of [14C]serine into phosphatidylserine by the base exchange reaction in Ehrlich ascites tumor cells is inhibited by 30% by glucose and by 60% by 2-deoxyglucose (10 mM each). The inhibition by thapsigargin (0.2 microM) amounts to 80%. This inhibition is interpreted as being due to depletion of calcium stores in the endoplasmic reticulum and is compatible with the previous observation [Teplova, V. V., Bogucka, K., Czyz, A., Evtodienko, Yu.V., Duszyński, J., and Wojtczak, L. (1993) Biochem. Biophys. Res. Commun. 196, 1148-1154] that glucose and deoxyglucose elicit an increase of cytoplasmic [Ca2+] at the expense of intracellular Ca2+ stores and with the finding [Barańska, J. (1989) FEBS Lett. 256, 33-37] that the base exchange reaction requires high concentration of Ca2+ within the endoplasmic reticulum lumen.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Rakowska M,Wojtczak L

doi

10.1006/bbrc.1995.1187

subject

Has Abstract

pub_date

1995-02-06 00:00:00

pages

300-5

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(85)71187-4

journal_volume

207

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Plasma lipoproteins mediate platelet adhesion.

    abstract：:Platelet adhesion to VLDL, LDL, HDL, and to a mixture of purified apolipoproteins was examined. Platelets adhered to all the classes of lipoproteins tested. VLDL and the apolipoprotein mixture promoted the greatest degree of adhesion. Platelet adhesion was inhibited by addition of EDTA, RGD-containing peptides and ant...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80180-9

    authors： Kowalska MA,Tuszynski GP,Capuzzi DM

    更新日期：1990-10-15 00:00:00

  • Replacement of methionine as the axial ligand of Achromobacter cycloclastes cytochrome c554 at high pH values revealed by absorption, EPR and MCD spectroscopy.

    abstract：:Cytochrome c554 from the denitrifying bacterium Achromobacter cycloclastes is a monoheme class II c-type cytochrome with a His-Met axial coordination at neutral pH. The amino acid composition and the N-terminal sequence of the cytochrome have been determined. Subsequent determination of the pH-dependence of the redox ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2434

    authors： Saraiva LM,Thomson AJ,Le Brun NE,Liu MY,Payne WJ,LeGall J,Moura I

    更新日期：1994-10-14 00:00:00

  • Expression profile analysis of colon cancer cells in response to sulindac or aspirin.

    abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) have a preventive effect against colorectal cancer. Although inhibition of cyclooxygenase-2 plays a crucial role in the suppression of tumors, precise mechanisms of their action remain to be disclosed. To identify genes involved in the growth-suppressive effect of NSAIDs, ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2002.6648

    authors： Iizaka M,Furukawa Y,Tsunoda T,Akashi H,Ogawa M,Nakamura Y

    更新日期：2002-03-29 00:00:00

  • Mouse thymoma cell line expresses a gluconeogenic enzyme, fructose 1,6-bisphosphatase.

    abstract：:Fructose 1,6-bisphosphatase was observed in a thymic lymphoma cell line, WEH17.1 (11.5 +/- 0.8 munits/mg cytosol protein). Only a trace amount of the enzyme activity was observed in normal thymus tissue. The WEH17.1 enzyme had a pH optimum at around 7.5. The AMP-concentration giving 50% inhibition of the activity was ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)92811-8

    authors： Mizunuma H,Tashima Y

    更新日期：1989-02-15 00:00:00

  • Detection of purine cytosine permease of S. cerevisiae: use of antibodies against a synthetic peptide corresponding to a predicted sequence in the N-terminal domain of the protein.

    abstract：:A synthetic peptide, selected in the predicted N-terminal amino-acid sequence of the purine cytosine permease (gene FCY2), linked to albumins proved a remarkably good immunogen in rabbits. In ELISA, sera reacted with the synthetic peptide and with specific proteins of plasma-membrane-enriched fractions of mutant Sacch...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.2489

    authors： Grandier-Vazeille X,Neaud V,Geoffre S

    更新日期：1993-12-15 00:00:00

  • DMSO increases tyrosine residue phosphorylation in membranes from murine erythroleukemia cells.

    abstract：:Phosphorylation of membranes from murine erythroleukemia cells was performed in the presence and absence of the polar solvent dimethyl sulfoxide. Quantitation of the phosphoamino acid content revealed that DMSO stimulated phosphotyrosine accumulation by three-fold; serine and threonine phosphorylation decreased signif...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91479-1

    authors： Earp HS,Rubin RA,Austin KS,Dy RC

    更新日期：1983-04-29 00:00:00

  • Chemical induction of cellular antioxidants affords marked protection against oxidative injury in vascular smooth muscle cells.

    abstract：:Extensive evidence suggests that reactive oxygen species are critically involved in the pathogenesis of cardiovascular diseases, such as atherosclerosis and myocardial ischemia-reperfusion injury. Consistent with this concept, administration of exogenous antioxidants has been shown to be protective against oxidative c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2002.6614

    authors： Cao Z,Li Y

    更新日期：2002-03-22 00:00:00

  • Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts.

    abstract：:Our previous studies showed that basic fibroblast growth factor 2 (FGF2) null mice display markedly reduced bone mass and bone formation. However, the mechanism by which FGF2 regulates bone mass or bone formation is not fully defined. Activating transcription factor 4 (ATF4), one member of activating transcription fac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.11.059

    authors： Fei Y,Xiao L,Hurley MM

    更新日期：2010-01-01 00:00:00

  • Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA.

    abstract：:HMGB1 (high-mobility group B1) is a ubiquitously expressed bifunctional protein that acts as a nuclear protein in cells and also as an inflammatory mediator in the extracellular space. HMGB1 changes its functions according to the redox states in both intra- and extra-cellular environments. Two cysteines, Cys23 and Cys...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：

    authors： Wang J,Tochio N,Takeuchi A,Uewaki J,Kobayashi N,Tate S

    更新日期：2013-11-29 00:00:00

  • Cholesterol depletion induces ANTXR2-dependent activation of MMP-2 via ERK1/2 phosphorylation in neuroglioma U251 cell.

    abstract：:Cholesterol is a critical component of lipid rafts implicated in regulating multiple signal transduction. The anthrax toxin receptor 2 (ANTXR2) is a type I membrane protein acting as the second receptor for the anthrax toxin. In this study, we first investigated the association between cholesterol and ANTXR2. We provi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.06.001

    authors： Zou J,Xu L,Ju Y,Zhang P,Wang Y,Zhang B

    更新日期：2014-09-12 00:00:00

  • Circadian expression of clock and screening of clock-controlled genes in peripheral lymphocytes of rat.

    abstract：:In this paper, the circadian pattern of Clock and genes mediated by the Clock was investigated in peripheral lymphocytes of rats. Circadian rhythms of Clock are found under the regimes of constant darkness (DD) and 12-h light-12-h dark (LD12:12h), with the peak phase at CT7 and ZT21, respectively. Ten differential cDN...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.08.228

    authors： Du YZ,Fan SJ,Meng QH,Wang GQ,Tong J

    更新日期：2005-11-04 00:00:00

  • Interaction between histone H1 and non-histone HMG14 detected by chemical cross-linking.

    abstract：:The interaction between histone H1 and non-histones HMG14 and HMG17 has been studied by chemical cross-linking. Cross-linking kinetics show the appearance of discrete bands which correspond to the interaction between H1 and HMG14. Interaction between H1 and HMG17 has not been detected. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91670-4

    authors： Espel E,Bernués J,Querol E,Martínez P,Barris A,Lloberas J

    更新日期：1983-12-28 00:00:00

  • Stimulation of Ca2+ release-activated Ca2+ channels as a potential mechanism involved in non-genomic 1,25(OH)2-vitamin D3-induced Ca2+ entry in skeletal muscle cells.

    abstract：:As in other vitamin D target cells, activation of voltage-dependent Ca2+ channels (VDCC) mediates the fast, non-genomic, 1,25(OH)2D3 stimulation of Ca2+ influx in skeletal muscle cells (SMC). 1,25(OH)2D3 has also been shown to rapidly induce the release of Ins(1,4,5)P3 in SMC. Experiments were performed to investigate...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7501

    authors： Vazquez G,de Boland AR,Boland R

    更新日期：1997-10-20 00:00:00

  • Inhibition of neuroglandular antigen (NGA) glycosylation by phorbol ester in human melanoma cells.

    abstract：:NGA is a human melanoma-associated antigen recognized by a panel of murine monoclonal antibodies developed in this laboratory. NGA consists of a 23.5 kDa core protein which is glycosylated in vivo to give a family of glycoproteins (30-60 kDa). Treatment of human melanoma G361 cells with the phorbol ester PMA resulted ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)92798-8

    authors： Feyles V,Dixon WT,Sikora LK,Jerry LM

    更新日期：1989-02-15 00:00:00

  • The RNA-binding protein Cpeb4 is a novel positive regulator of osteoclast differentiation.

    abstract：:Cytoplasmic polyadenylation element binding (CPEB) proteins are RNA-binding proteins involved in translational regulation of the specific target mRNAs and control function of various organs including brain, liver and hematopoietic system. However, the role of CPEB proteins during osteoclast differentiation remains unc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.05.089

    authors： Arasaki Y,Li M,Akiya T,Nozawa I,Ezura Y,Hayata T

    更新日期：2020-08-06 00:00:00

  • Enhanced v-Src-induced oncogenic transformation in the absence of focal adhesion kinase is mediated by phosphatidylinositol 3-kinase.

    abstract：:We showed previously [K. Moissoglu, I.H. Gelman, J. Biol. Chem. 278 (2003) 47946-47959] that oncogenic v-Src could induce 7- to 10-fold greater anchorage-independent growth (AIG) in FAK-null mouse embryo fibroblasts (MEF) compared to those expressing FAK. Here, we demonstrate that the enhanced AIG (eAIG) correlates wi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.03.025

    authors： Moissoglu K,Sachdev S,Gelman IH

    更新日期：2005-05-13 00:00:00

  • Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect.

    abstract：:Regeneration and functional reconstruction of peripheral nerve defects remained a significant clinical challenge. Nerve guide conduits, with seed cells or neurotrophic factors (NTFs), had been widely used to improve the repair and regeneration of injured peripheral nerve. Pyrroloquinoline quinone (PQQ) was an antioxid...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.12.121

    authors： Luo L,Gan L,Liu Y,Tian W,Tong Z,Wang X,Huselstein C,Chen Y

    更新日期：2015-02-20 00:00:00

  • Inhibition of periarterial nerve stimulation-induced vasodilation of the mesenteric arterial bed by CGRP (8-37) and CGRP receptor desensitization.

    abstract：:We provide the first functional evidence that calcitonin gene-related peptide (8-37) induces a direct vasoconstriction and reversibly antagonizes vasodilation of the mesenteric arterial bed induced by calcitonin gene-related peptide (CGRP) suggesting that CGRP (8-37) is a competitive antagonist of vascular CGRP recept...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)92390-l

    authors： Han SP,Naes L,Westfall TC

    更新日期：1990-04-30 00:00:00

  • alphaA- and alphaB-crystallins protect glucose-6-phosphate dehydrogenase against UVB irradiation-induced inactivation.

    abstract：:alpha-Crystallin, a major eye lens protein, has been shown to function like a molecular chaperone by suppressing the aggregation of other proteins induced by various stress conditions. Ultraviolet (UV) radiation is known to cause structural and functional alterations in the lens macromolecules. Earlier we observed tha...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.4642

    authors： Reddy GB,Reddy PY,Suryanarayana P

    更新日期：2001-04-06 00:00:00

  • Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating occludin, claudin-1 and E-cadherin expression.

    abstract：:The Apical Junctional Complex (AJC) encompassing the tight junction (TJ) and adherens junction (AJ) plays a pivotal role in regulating epithelial barrier function and epithelial cell proliferative processes through signaling events that remain poorly characterized. A potential regulator of AJC protein expression is Gl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.05.164

    authors： Severson EA,Kwon M,Hilgarth RS,Parkos CA,Nusrat A

    更新日期：2010-07-02 00:00:00

  • Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.

    abstract：:Endoplasmic reticulum (ER) stress has been shown to play a key role during the initiation and clinical progression of the cardiovascular diseases, such as atherosclerosis. We have recently shown that expression of tissue factor pathway inhibitor (TFPI) in human monocyte-derived macrophages (MDMs) was induced by choles...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.07.070

    authors： Espada S,Stavik B,Holm S,Sagen EL,Bjerkeli V,Skjelland M,Dahl TB,Espevik T,Kanse S,Sandset PM,Skretting G,Halvorsen B

    更新日期：2017-09-16 00:00:00

  • Functional characterization of the heterodimeric sweet taste receptor T1R2 and T1R3 from a New World monkey species (squirrel monkey) and its response to sweet-tasting proteins.

    abstract：:The family C G protein-coupled receptor (GPCR) T1R2 and T1R3 heterodimer functions as a broadly acting sweet taste receptor. Perception of sweet taste is a species-dependent physiological process. It has been widely reported that New World monkeys and rodents are not able to perceive some of the artificial sweeteners ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.09.083

    authors： Liu B,Ha M,Meng XY,Khaleduzzaman M,Zhang Z,Li X,Cui M

    更新日期：2012-10-19 00:00:00

  • OK-1035, a selective inhibitor of DNA-dependent protein kinase.

    abstract：:Screening for inhibitors of DNA-dependent protein kinase (DNA-PK) revealed 3-cyano-5-(4-pyridyl)-6-hydrazonomethyl-2-pyridone, designated OK-1035, to be a potent and selective inhibitor. When a synthetic peptide was used as a substrate, OK-1035 caused 50% inhibition of DNA-PK activity at 8 microM, a concentration more...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.2431

    authors： Take Y,Kumano M,Hamano Y,Fukatsu H,Teraoka H,Nishimura S,Okuyama A

    更新日期：1995-10-04 00:00:00

  • Molecular cloning of a new member of the Rab protein family, Rab 26, from rat pancreas.

    abstract：:Members of the Rab family of low molecular weight GTP-binding (LMWG) proteins regulate vesicular transport; distinct Rab proteins are located in specific vesicular compartments within the exocytotic and endocytotic pathway. Pancreatic zymogen granules possess multiple LMWG. Rab 3A, however, which has been suggested to...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1277

    authors： Wagner AC,Strowski MZ,Göke B,Williams JA

    更新日期：1995-02-27 00:00:00

  • CD2AP contributes to cell migration and adhesion in cultured gastric epithelium.

    abstract：:The potential association of CD2AP with the adherens junction protein E-cadherin, co-localization with the actin cytoskeleton, and involvement in cell migration was investigated in cultured rat gastric mucosal cells. In stationary cells, CD2AP was localized perinuclearly while E-cadherin was expressed along cell-cell ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.04.140

    authors： Mustonen H,Lepistö A,Lehtonen S,Lehtonen E,Puolakkainen P,Kivilaakso E

    更新日期：2005-07-01 00:00:00

  • Conditional transformation of mouse pancreatic epithelial cells: an in vitro model for analysis of genetic events in pancreatocarcinogenesis.

    abstract：:Pancreatic ductal adenocarcinomas arise through the accumulation of certain genetic alterations including ras, p16, p53, and DPC4. We found that activation of ras and inactivation of p53 could cooperatively induce in vitro tumorigenicity in conditionally immortalized pancreatic epithelial (IMPE) cells. IMPE cells were...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.04.196

    authors： Koizumi M,Ito D,Fujimoto K,Toyoda E,Kami K,Mori T,Doi R,Whitehead R,Imamura M

    更新日期：2004-06-25 00:00:00

  • Identification of an unconventional nuclear localization signal in human ribosomal protein S2.

    abstract：:Ribosomal proteins must be imported into the nucleus after being synthesized in the cytoplasm. Since the rpS2 amino acid sequence does not contain a typical nuclear localization signal, we used deletion mutant analysis and rpS2-beta-galactosidase chimeric proteins to identify the nuclear targeting domains in rpS2. Nuc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.07.069

    authors： Antoine M,Reimers K,Wirz W,Gressner AM,Müller R,Kiefer P

    更新日期：2005-09-16 00:00:00

  • Cyclic AMP decreases LDL catabolism and cholesterol synthesis in the human hepatoma cell line HepG2.

    abstract：:A 24h pretreatment of the human hepatoma cell line HepG2 with dibutyryl cyclic AMP in the presence of theophylline induced a dose dependent decrease in low density lipoprotein binding, uptake and degradation. This effect is most likely due to a reduction of the LDL receptor number. Sterol synthesis from sodium acetate...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80858-1

    authors： Maziere C,Maziere JC,Salmon S,Auclair M,Mora L,Moreau M,Polonovski J

    更新日期：1988-10-14 00:00:00

  • The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception.

    abstract：:Peripheral noxious stimulation leads to phosphorylation and thereby activation of the transcription factor CREB in the spinal cord. CREB phosphorylation occurs mainly at serine 133, but the phosphorylation site at serine 142 may also be important. We investigated the impact of spinal CREB protein levels and phosphoryl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.07.148

    authors： Niederberger E,Ehnert C,Gao W,Coste O,Schmidtko A,Popp L,Gall CV,Korf HW,Tegeder I,Geisslinger G

    更新日期：2007-10-12 00:00:00

  • Effect of acetylcholine on the electrophysiology and proliferative response of human lymphocytes.

    abstract：:Using the patch-clamp technique, we determined that 1-15 mM extracellular acetylcholine reduced whole-cell n-type K+ currents in human peripheral blood lymphocytes and accelerated their inactivation. The percentage increase in K+ channel inactivation rate and the degree of drug induced block were independent of membra...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.1351

    authors： Gáspár R Jr,Varga Z,Bene L,Marcheselli F,Pieri C,Damjanovich S

    更新日期：1996-09-13 00:00:00