Interaction between histone H1 and non-histone HMG14 detected by chemical cross-linking.

abstract：:The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7Å resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised of a β-sheet and three α-helices forming a cone-like shape. H...

journal_title：Biochemical and biophysical research communications

authors： Vognsen T,Kristensen O

更新日期：2012-03-30 00:00:00

abstract：:Protein kinase D (PKD) has been established as a negative modulator of the c-Jun N-terminal kinase (JNK) signaling pathway. We previously demonstrated that induced expression of constitutively active PKD (PKD-S744/748E) that mimics phosphorylation by PKC is sufficient to attenuate epidermal growth factor (EGF) stimula...

journal_title：Biochemical and biophysical research communications

authors： Hurd C,Rozengurt E

更新日期：2003-03-21 00:00:00

abstract：:In the present report we analyze by reverse transcription (RT) and polymerase chain reaction (PCR) the expression of vasoactive intestinal peptide receptors (VIP-R) in rat thymocytes and peripheral T and B lymphocytes. We have obtained a specific VIP-R cDNA product of 311 bp identical in size to that obtained from lun...

journal_title：Biochemical and biophysical research communications

authors： Gomariz RP,Garrido E,Leceta J,Martinez C,Abalo R,Delgado M

更新日期：1994-09-30 00:00:00

abstract：:Members of the Ca2+/calmodulin dependent protein kinase (CaMK) family and a CaMK cascade have been identified and well characterized in the brain, but little is known about their equivalents in the heart. Thus only CaMKII and its function have been reported so far. Therefore, we purified and characterized CaMKI and Ca...

journal_title：Biochemical and biophysical research communications

authors： Uemura A,Naito Y,Matsubara T,Hotta N,Hidaka H

更新日期：1998-08-19 00:00:00

abstract：:The in vitro effects of various steroid and thyroid hormones on synthesis of rat atrial natriuretic peptide (rANP) were studied using new-born rat atrial myocytes in culture. Dexamethasone, testosterone and triiodothyronine markedly stimulated both synthesis and secretion of immunoreactive (IR)-rANP with the same peak...

journal_title：Biochemical and biophysical research communications

authors： Matsubara H,Hirata Y,Yoshimi H,Takata S,Takagi Y,Iida T,Yamane Y,Umeda Y,Nishikawa M,Inada M

更新日期：1987-05-29 00:00:00

abstract：:The mechanism underlying the wogonin-mediated increase in the expression of suppressor of cytokine signaling 3 (SOCS3) is unclear. Promoter deletion assay results revealed that wogonin-induced SOCS3 expression is dependent on the AP-1 consensus sequences and two STAT responsive elements (TTACAAGAA and TTCCAGGAA) in th...

journal_title：Biochemical and biophysical research communications

authors： Nam KW,Chae S,Song HY,Mar W,Han MD

更新日期：2014-08-08 00:00:00

abstract：:The effect of steroid chemical structure on steroid-lipid interaction is studied in sonicated dipalmitoyl phosphatidylcholine vesicles by steady-state and time-resolved fluorescence anisotropy techniques using diphenylhexatriene as probe. A large number of cholesterol derivatives and steroids, some of them being precu...

journal_title：Biochemical and biophysical research communications

authors： Vincent M,Gallay J

更新日期：1983-06-29 00:00:00

abstract：:Growing evidence indicates that circular RNA (circRNA) plays an important role in the regulation of tumor biological behaviors. In this study, we aimed to explore the role of a novel circRNA, circ_0034642, in glioma. qRT-PCR was conducted to evaluate the levels of circ_0034642 in glioma tissues and cells. In addition,...

journal_title：Biochemical and biophysical research communications

authors： Yang M,Li G,Fan L,Zhang G,Xu J,Zhang J

更新日期：2019-01-15 00:00:00

abstract：:We describe here two human VIP receptor cDNA clones isolated from a jejunal epithelial cell cDNA library. The hIVR8 cDNA encodes a human VIP receptor consisting of 460 amino acids and has seven putative transmembrane domains like other G protein-coupled receptors. When expressed in COS-7 cells, hIVR8 conferred specifi...

journal_title：Biochemical and biophysical research communications

authors： Couvineau A,Rouyer-Fessard C,Darmoul D,Maoret JJ,Carrero I,Ogier-Denis E,Laburthe M

更新日期：1994-04-29 00:00:00

abstract：:Activation of seven-transmembrane G-protein coupled receptor (GPCR) mediates extracellular signals into intracellular responses. G-protein coupled receptor 55 (GPR55) is one of GPCRs and activated by endogenous cannabinoids. A family of regulators of G-protein signaling (RGS) stimulates GTP hydrolysis of alpha subunit...

journal_title：Biochemical and biophysical research communications

authors： Jang H,Kim Y,Ghil S

更新日期：2020-12-17 00:00:00

abstract：:Age-related hearing loss (ARHL) is a neurodegenerative disease associated with an aged population. ARHL is influenced by biological factors such as aging, sex difference, and atherosclerosis. The mechanisms of ARHL caused by atherosclerosis have not been previously determined in apolipoprotein E knockout (ApoE KO) mal...

journal_title：Biochemical and biophysical research communications

authors： Kim YY,Chao JR,Kim C,Kim B,Thi-Thanh Nguyen P,Jung H,Chang J,Lee JH,Suh JG

更新日期：2020-03-12 00:00:00

abstract：:Prostate cancer (PCa) is the second leading cause of cancer-associated mortality in men. Speckle-type pox virus and zinc finger protein (SPOP), the most frequently mutated gene in PCa, functions as a tumor suppressor via degradation of cancer-promoting substrates. However, its upstream regulation in PCa metastasis rem...

journal_title：Biochemical and biophysical research communications

authors： Lv W,Huan M,Yang W,Gao Y,Wang K,Xu S,Zhang M,Ma J,Wang X,Chen Y,Li L

更新日期：2020-08-27 00:00:00

abstract：:Wheat germ phosphoglycerate mutase, exposed to 3.4 M guanidinium chloride at 22 degrees C and pH 7.8, slowly undergoes time-dependent inactivation which can be fully reversed by adding excess Co2+ or Mn2+ to a 50-fold dilution of the denaturing medium. Titration of the denatured enzyme with either Co2+ or Mn2+ shows t...

journal_title：Biochemical and biophysical research communications

authors： Smith GC,McWilliams AD,Hass LF

更新日期：1986-04-14 00:00:00

abstract：:In this study, acetosyringone was identified as one of the major extracellular phenolics in tobacco suspension cells and was shown to have bioactive properties that influence early events in plant-bacterial pathogenesis. In our model system, tobacco cell suspensions treated with bacterial isolate Pseudomonas syringae ...

journal_title：Biochemical and biophysical research communications

authors： Baker CJ,Mock NM,Whitaker BD,Roberts DP,Rice CP,Deahl KL,Aver'yanov AA

更新日期：2005-03-04 00:00:00

abstract：:We investigated the molecular effect and signal pathway of icariin, a major flavonoid of Epimedium koreanum Nakai, on angiogenesis. Icariin stimulated in vitro endothelial cell proliferation, migration, and tubulogenesis, which are typical phenomena of angiogenesis, as well as increased in vivo angiogenesis. Icariin a...

journal_title：Biochemical and biophysical research communications

authors： Chung BH,Kim JD,Kim CK,Kim JH,Won MH,Lee HS,Dong MS,Ha KS,Kwon YG,Kim YM

更新日期：2008-11-14 00:00:00

abstract：:Tissue factor (TF) is an initiation factor for blood coagulation and its expression is induced on endothelial cells during inflammatory or immune responses. We designed an antisense oligodeoxynucleotide (AS-1/TF) for rat TF and studied its effect on hepatic ischemic reperfusion injury. AS-1/TF was delivered intravenou...

journal_title：Biochemical and biophysical research communications

authors： Nakamura K,Kadotani Y,Ushigome H,Akioka K,Okamoto M,Ohmori Y,Yaoi T,Fushiki S,Yoshimura R,Yoshimura N

更新日期：2002-09-27 00:00:00

abstract：:Borrelidin exhibits a wide spectrum of biological activities and has been considered as a non-competitive inhibitor of threonyl-tRNA synthetase (ThrRS). However, the detailed mechanisms of borrelidin against ThrRS, especially borrelidin binding site on ThrRS, are still unclear, which limits the development of novel bo...

journal_title：Biochemical and biophysical research communications

authors： Li M,Zhang J,Liu C,Fang B,Wang X,Xiang W

更新日期：2014-09-05 00:00:00

abstract：:The effect of cellular stress factors, the hyperthermia and the acidification of culture medium, on mechano-growth factor (MGF) synthesis by murine myoblasts in culture was investigated. Hyperthermia was shown to stimulate MGF expression both in primary myoblasts and in differentiated multinuclear myotubes. The induct...

journal_title：Biochemical and biophysical research communications

authors： Kravchenko IV,Furalyov VA,Popov VO

更新日期：2008-10-17 00:00:00

abstract：:The PKC alpha, beta, delta, epsilon and zeta isoenzyme changes in the rat kidney cortex have been investigated after temporary occlusion of the renal artery, followed by reperfusion for up to 4 h. Increased PKC alpha, delta and epsilon immunoreactivity and PKC alpha activity occurred within 60 min of postischemic refl...

journal_title：Biochemical and biophysical research communications

authors： La Porta CA,Comolli R

更新日期：1993-03-31 00:00:00

abstract：:Ribosome modulation factor (RMF) is involved in stabilization of ribosomes during the transition from exponential growth to the stationary growth phase in Escherichia coli. A deficiency of RMF is known to reduce cell viability. Overaccumulation of spermidine also leads to a decrease in cell viability and to a decrease...

journal_title：Biochemical and biophysical research communications

authors： Apirakaramwong A,Fukuchi J,Kashiwagi K,Kakinuma Y,Ito E,Ishihama A,Igarashi K

更新日期：1998-10-20 00:00:00

abstract：:SpYPT1p belongs to a family of ras-like GTP-binding proteins which is believed to be involved in the regulation of intracellular vesicular trafficking. We have analyzed the processing of this protein in its natural environment, the fission yeast Schizosaccharomyces pombe, and when expressed in transfected mammalian CO...

journal_title：Biochemical and biophysical research communications

authors： Giannakouros T,Newman CM,Armstrong J,Magee AI

更新日期：1993-05-14 00:00:00

abstract：:Recent evidence suggested that human cardiac stem cells (hCSCs) may have the clinical application for cardiac repair; however, their characteristics and the regulatory mechanisms of their growth have not been fully investigated. Here, we show the novel property of hCSCs with respect to their origin and tissue distribu...

journal_title：Biochemical and biophysical research communications

authors： Tateishi K,Ashihara E,Honsho S,Takehara N,Nomura T,Takahashi T,Ueyama T,Yamagishi M,Yaku H,Matsubara H,Oh H

更新日期：2007-01-19 00:00:00

abstract：:Schisanhenol (Sal) did not diminish the antitumor activity of adriamycin in mice bearing P388 ascites tumor. Sal did not antagonize the suppressive effect of adriamycin on DNA synthesis and cell proliferation in an L1210 ascitic tumor cell culture. Furthermore, Sal at the concentration of 0.1, 0.25, or 1 mM accelerate...

journal_title：Biochemical and biophysical research communications

authors： Lin TJ,Liu GT

更新日期：1991-07-15 00:00:00

abstract：:Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and ...

journal_title：Biochemical and biophysical research communications

authors： Sinha YN,Jacobsen BP

更新日期：1988-10-14 00:00:00

abstract：:Engineering of secreted protease variants exhibiting altered substrate specificity is a challenging task because effective screening methods for the desired property are not available yet. In this study, we sought to obtain variants of Kex2, a yeast Golgi protease, which exhibit altered P2 specificity. We first random...

journal_title：Biochemical and biophysical research communications

authors： Han HE,Rho SH,Lee YJ,Park WJ

更新日期：2005-12-02 00:00:00

abstract：:Cellular Ca(2+) homeostasis is maintained through the integrated and coordinated function of Ca(2+) transport molecules, Ca(2+) buffers and sensors. These molecules are associated with the plasma membrane and different cellular compartments, such as the cytoplasm, nucleus, mitochondria, and cellular reticular network,...

journal_title：Biochemical and biophysical research communications

authors： Krebs J,Agellon LB,Michalak M

更新日期：2015-04-24 00:00:00

abstract：:It has been well established that estrogen is involved in the pathophysiology of breast cancer. Estrogen receptor (ER) alpha appears to promote the proliferation of cancer tissues, while ERbeta can protect against the mitogenic effect of estrogen in breast tissue. The expression status of ERalpha and ERbeta may greatl...

journal_title：Biochemical and biophysical research communications

authors： Koyama S,Wada-Hiraike O,Nakagawa S,Tanikawa M,Hiraike H,Miyamoto Y,Sone K,Oda K,Fukuhara H,Nakagawa K,Kato S,Yano T,Taketani Y

更新日期：2010-02-12 00:00:00

abstract：:Modern proteomics approaches include techniques to examine the expression, localization, modifications, and complex formation of proteins in cells. In order to address issues of protein function in vitro using classical biochemical and biophysical approaches, high-throughput methods of cloning the appropriate reading ...

journal_title：Biochemical and biophysical research communications

authors： Huang RY,Boulton SJ,Vidal M,Almo SC,Bresnick AR,Chance MR

更新日期：2003-08-08 00:00:00

abstract：:alpha-Difluoromethylornithine (DFMO) has been widely used for determining the amounts of ornithine decarboxylase (ODC) in cells. However, we have now found that DFMO does not react with ODC-antizyme complex, indicating that the amounts of radioactive DFMO bound to the protein may not reflect the amounts of ODC in crud...

journal_title：Biochemical and biophysical research communications

authors： Kitani T,Fujisawa H

更新日期：1986-06-30 00:00:00

abstract：:Antithrombin inhibits chemokine-induced migration of neutrophils by activating heparan sulfate proteoglycan-dependent signaling. Mechanisms of antithrombin's effects on neutrophils were, therefore, studied by testing function and expression of heparan sulfate proteoglycans in RT-PCR or flow cytometry and cell migratio...

journal_title：Biochemical and biophysical research communications

authors： Kaneider NC,Egger P,Dunzendorfer S,Wiedermann CJ

更新日期：2001-09-14 00:00:00