Immunocytochemical evidence for gonadoliberin in rat anterior pituitary gland.

abstract：:Methanol extracts of rat plasma resulted in release of prolactin (PRL) from rat hemipituitaries in vitro with a linear log-dose relationship. This prolactin-releasing factor (PRF)-like activity was not altered in plasma from rats treated with bromocryptine or chlorpromazine despite significant suppression and stimulat...

journal_title：Neuroendocrinology

authors： Garthwaite TL,Hagen TC

更新日期：1979-01-01 00:00:00

abstract：:We report the development of a radioimmunoassay for prepro-TRH(160-169) (PS4), a thyrotropin-releasing hormone (TRH) enhancing peptide, and its use in characterizing the effect of electroconvulsive seizures on the levels of this peptide in various brain regions of male Wistar rats. We found that electroconvulsive seiz...

journal_title：Neuroendocrinology

authors： Pekary AE,Sattin A,Lloyd RL

更新日期：1997-05-01 00:00:00

abstract：:The effects of hepatic vagotomy upon the circadian rhythm of lipogenesis and body fat store levels were tested in seasonally obese Syrian hamsters. Lipogenesis was studied 8 weeks after surgery by measuring the incorporation of label into epididymal and retroperitoneal fat pad lipid in animals killed 30 min after intr...

journal_title：Neuroendocrinology

authors： Martin DD,Cincotta AH,Meier AH

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Type I gastric carcinoids (TIGCs) are neuroendocrine neoplasms arising from enterochromaffin-like cells in atrophic body gastritis. Data regarding their evolution in prospective series are scarce, thus treatment and follow-up are not codified. Our aim was to evaluate clinical outcome and recurrence in TIGCs ...

journal_title：Neuroendocrinology

authors： Merola E,Sbrozzi-Vanni A,Panzuto F,D'Ambra G,Di Giulio E,Pilozzi E,Capurso G,Lahner E,Bordi C,Annibale B,Delle Fave G

更新日期：2012-01-01 00:00:00

abstract：:We have investigated the hypothesis that administration of progesterone to estrogen-treated ovariectomized (OVX) rats enhances the stimulatory effects of neuropeptide Y (NPY) on the secretion of luteinizing hormone-releasing hormone (LHRH) from median eminence (ME) fragments in vitro. Adult rats were bilaterally OVX a...

journal_title：Neuroendocrinology

authors： Sabatino FD,Collins P,McDonald JK

更新日期：1990-12-01 00:00:00

abstract：:In vivo single-unit extracellular recording was used to assess neuronal membrane sensitivity at the level of the midbrain central gray (MCG) to the iontophoresis of luteinizing hormone releasing hormone (LHRH) and beta-endorphin (beta-END). The percentage of change in firing rate was evaluated to determine the effect ...

journal_title：Neuroendocrinology

authors： Schiess MC,Dudley CA,Moss RL

更新日期：1987-06-01 00:00:00

abstract：:The effect of in vivo corticosterone manipulation on binding sites for the excitatory neurotransmitter glutamate was determined using radioligand binding to rat brain cryostat sections and crude synaptic membranes. 3H-glutamate binding to regions of the dorsal hippocampal formation was significantly decreased in adren...

journal_title：Neuroendocrinology

authors： Halpain S,McEwen BS

更新日期：1988-09-01 00:00:00

abstract：:Thyroid hormones and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling play a significant role in the structural development of the cerebellum, respectively. In the present study, the possible contribution of neuronal NO synthase (NOS) and cGMP in the thyroid hormone-induced structural changes was invest...

journal_title：Neuroendocrinology

authors： Serfozo Z,de Vente J,Elekes K

更新日期：2009-01-01 00:00:00

abstract：:The present study investigates the role of melanotrope proopiomelanocortin-derived peptide in the interrenal stress response to different stressors in male gilthead sea bream, Sparus aurata. Plasma cortisol and acetyl salmon endorphin (acetyl s-EP), as well as pituitary acetyl s-EP contents, were measured during two s...

journal_title：Neuroendocrinology

authors： Mosconi G,Gallinelli A,Polzonetti-Magni AM,Facchinetti F

更新日期：1998-08-01 00:00:00

abstract：:(+/-)p-Chloroamphetamine hydrochloride, at doses of 1-8 mg/kg i.p. in rats, caused a dose-related increase in serum corticosterone concentration. The increase occurred rapidly, within 30 min, and was over within 4 h. Evidence that the increase was mediated by serotonin release consisted of the following findings: (1) ...

journal_title：Neuroendocrinology

authors： Fuller RW,Snoddy HD

更新日期：1980-08-01 00:00:00

abstract：:Infusion of the three human prepro-VIP derived peptides [vasoactive intestinal peptide (VIP), peptide histidine methionine (PHM) and the newly discovered peptide histidine valine (PHV-42)] at a constant nominal rate of 5 pmol/kg/min in 6 healthy volunteers for 60 min resulted in plateau plasma levels of 56,475 and 1,0...

journal_title：Neuroendocrinology

authors： Yiangou Y,Gill JS,Chrysanthou BJ,Burrin J,Bloom SR

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:The expression of somatostatin receptors (SSTRs) and dopamine receptor 2 (DR2) in neuroendocrine tumors is of clinical importance as somatostatin analogues and dopamine agonists can be used for their localization and/or treatment. The objective of this study is to examine the expression of the five SSTR subty...

journal_title：Neuroendocrinology

authors： Kanakis G,Grimelius L,Spathis A,Tringidou R,Rassidakis GZ,Öberg K,Kaltsas G,Tsolakis AV

更新日期：2015-01-01 00:00:00

abstract：:Increases in the level of cAMP stimulate the secretion of GnRH from GT1 GnRH neuronal cells. We hypothesized that cyclic nucleotide phosphodiesterases (PDEs), the enzymes that hydrolyze cAMP, may constitute a negative feedback signaling mechanism for GnRH regulation by decreasing the level of cAMP. GT1 cells were show...

journal_title：Neuroendocrinology

authors： Sakakibara H,Conti M,Weiner RI

更新日期：1998-12-01 00:00:00

abstract：:Phase relation between plasma corticosterone and locomotor activity rhythms was analyzed in individual rats with selective lesions of suprachiasmatic nuclei (SCN). SCN in Wistar male rats were selectively coagulated electrically and the extent of SCN destruction was examined histologically. Spontaneous locomotor activ...

journal_title：Neuroendocrinology

authors： Watanabe K,Hiroshige T

更新日期：1981-07-01 00:00:00

abstract：:The recent description of infertility in humans with loss-of-function mutations in genes for neurokinin B (NKB) or its receptor (NK3R) has focused attention on the importance of this tachykinin in the control of GnRH secretion. In a number of species, NKB neurons in the arcuate nucleus also produce two other neuropept...

journal_title：Neuroendocrinology

authors： Goodman RL,Coolen LM,Lehman MN

更新日期：2014-01-01 00:00:00

abstract：:Correlations between the specific binding of radiolabelled adrenoligands in frontal cortex and hypothalamus, and plasma testosterone levels were investigated in inbred mouse strains. Binding values were structure and genotype dependent. There were significant negative intrastrain and interstrain correlations between h...

journal_title：Neuroendocrinology

authors： Shishkina GT,Naumenko EV

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND/AIMS:Abuse of toluene products (e.g., glue-sniffing) primarily occurs during adolescence and has been associated with appetite suppression and weight impairments. However, the metabolic phenotype arising from adolescent inhalant abuse has never been fully characterised, and its persistence during abstinence ...

journal_title：Neuroendocrinology

authors： Crossin R,Andrews ZB,Sims NA,Pang T,Mathai M,Gooi JH,Stefanidis A,Oldfield BJ,Lawrence AJ,Duncan JR

更新日期：2018-01-01 00:00:00

abstract：:The possible role of prostaglandins (PGs) in the hypothalamic control of ovulation has been investigated by studying the effects of indomethacin (ID) and PGs on the release of luteinizing hormone-releasing hormone (LHRH) from hypothalamic synaptosomes. Female rats were chronically pretreated with ID on diestrus 2 (D2)...

journal_title：Neuroendocrinology

authors： Linton EA,Bennett GW,Whitehead SA

更新日期：1979-01-01 00:00:00

abstract：:In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

journal_title：Neuroendocrinology

authors： Clark M,Smith MA,Weiss SR,Post RM

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND/AIM:The mode of action of the somatostatin analog octreotide on neuro-endocrine tumour proliferation is largely unknown. Overexpression of the proto-oncogene Akt/PKB (protein kinase B) has been demonstrated in certain neuro-endocrine tumours: Akt activates downstream proteins including mTOR and p70S6K, which...

journal_title：Neuroendocrinology

authors： Grozinsky-Glasberg S,Franchi G,Teng M,Leontiou CA,Ribeiro de Oliveira A Jr,Dalino P,Salahuddin N,Korbonits M,Grossman AB

更新日期：2008-01-01 00:00:00

abstract：:The present study was undertaken to evaluate the 24-hour periodicity in serum prolactin levels subsequent to transecting the ascending serotonergic system or ablating the suprachiasmatic nuclei (SCN) of adult (185 g) female rats. The ascending serotonergic system was transected at the level of the rostral mesencephalo...

journal_title：Neuroendocrinology

authors： Dunn JD,Johnson DC,Castro AJ,Swenson R

更新日期：1980-08-01 00:00:00

abstract：:In the present study we demonstrated that TLQP-21, a biologically active peptide derived from the processing of the larger pro-VGF granin, plays a role in mammotrophic cell differentiation. We used an established in vitro model, the GH3 cell line, which upon treatment with epidermal growth factor develops a mammotroph...

journal_title：Neuroendocrinology

authors： Petrocchi Passeri P,Biondini L,Mongiardi MP,Mordini N,Quaresima S,Frank C,Baratta M,Bartolomucci A,Levi A,Severini C,Possenti R

更新日期：2013-01-01 00:00:00

abstract：:In rats anesthetized with sodium pentobarbital, adrenal venous blood samples were collected and analyzed for epinephrine and norepinephrine by the fluorometric method. Stimulation of the inferior fovea or adjacent areas resulted in a significant increase in epinephrine secretion. Stimulation of some other areas of the...

journal_title：Neuroendocrinology

authors： Matsui H

更新日期：1979-01-01 00:00:00

abstract：:The ability of dopamine receptor antagonists to stimulate prolactin release in rats with medial basal hypothalamic lesions was investigated. Starting levels of prolactin were elevated to approximately 400 ng/ml in animals in which the tuberoinfundibular dopaminergic neurons were completely destroyed by the lesion. In ...

journal_title：Neuroendocrinology

authors： Cheung CY,Neill AC,Weiner RI

更新日期：1981-06-01 00:00:00

abstract：:The potential involvement of the sympathoadrenal system in stress-induced secretion of peptides from the intermediate lobe of the pituitary gland and the activation of the pituitary-adrenal axis was studied. Male Wistar rats were subjected to control procedures, to sympathectomy by chronic administration (8 weeks) of ...

journal_title：Neuroendocrinology

authors： Kvetnansky R,Tilders FJ,van Zoest ID,Dobrakovova M,Berkenbosch F,Culman J,Zeman P,Smelik PG

更新日期：1987-04-01 00:00:00

abstract：:The effects of ablation of the nucleus medianus on drinking and vasopressin secretion were studied in male Long-Evans rats. The amount of water drunk in 1 h was assessed after subcutaneous injection of 5.8% NaCl (13.34 mosm/kg) or of angiotensin II (1.5 mg/kg). In a separate test with no water available, plasma vasopr...

journal_title：Neuroendocrinology

authors： Mangiapane ML,Thrasher TN,Keil LC,Simpson JB,Ganong WF

更新日期：1983-07-01 00:00:00

abstract：:An electrophysiological investigation was conducted on the connection of medial preoptic neurons with the median eminence and the basal and corticomedial amygdala in pentobarbital anesthesized male Sprague-Dawley rats. Of 411 medial preoptic neurons tested with median eminence stimuli, antidromic responses (mean laten...

journal_title：Neuroendocrinology

authors： Layton BS,Lafontaine S,Renaud LP

更新日期：1981-01-01 00:00:00

abstract：:Hyponatremia due to elevated arginine vasopressin (AVP) secretion increases mortality in liver failure patients. The mechanisms causing dysregulation of AVP secretion are unknown. Our hypothesis is that inappropriate AVP release associated with liver failure is due to increased brain-derived neurotrophic factor (BDNF)...

journal_title：Neuroendocrinology

authors： Balapattabi K,Little JT,Bachelor M,Cunningham JT

更新日期：2020-01-01 00:00:00

abstract：:Distribution and properties of receptors for gonadotropin-releasing hormone (GnRH) were analyzed in the brain of adult male rats. Binding of the iodinated GnRH agonist Des-Gly10-(D-Ala6)-GnRH ethylamide was studied in hippocampus and anterior pituitary using three convergent approaches: quantitative autoradiography on...

journal_title：Neuroendocrinology

authors： Leblanc P,Crumeyrolle M,Latouche J,Jordan D,Fillion G,L'Heritier A,Kordon C,Dussaillant M,Rostène W,Haour F

更新日期：1988-11-01 00:00:00

abstract：:A patch-clamp study was conducted on cultured frog pituitary melanotrophs, in order to investigate the effects of adrenaline on the electrical activity of these cells. In the whole-cell configuration, adrenaline (1 microM) caused hyperpolarization that was accompanied by a fall in membrane input resistance and a block...

journal_title：Neuroendocrinology

authors： Valentijn JA,Vaudry H,Cazin L

更新日期：1994-01-01 00:00:00