Expression of Somatostatin Receptors 1-5 and Dopamine Receptor 2 in Lung Carcinoids: Implications for a Therapeutic Role.

abstract：:Recent work has demonstrated that the brain has the capacity to synthesize impressive amounts of the gases nitric oxide (NO) and carbon monoxide (CO). There is growing evidence that these gaseous molecules function as novel neural messengers in the brain. This article reviews the pertinent literature concerning the pu...

journal_title：Neuroendocrinology

authors： Brann DW,Bhat GK,Lamar CA,Mahesh VB

更新日期：1997-06-01 00:00:00

abstract：:Interruption of hypothalamic growth hormone-releasing hormone (GHRH) secretion by administration of antiserum against GHRH (GHRH-ab) decreases growth hormone (GH) secretion and inhibits growth in rats. The present study was undertaken to investigate whether there is a period of accelerated or catch-up growth following...

journal_title：Neuroendocrinology

authors： Wehrenberg WB,Voltz DM,Cella SG,Müller EE,Gaillard RC

更新日期：1992-10-01 00:00:00

abstract：:The effects of angiotensin II (AII) and natriuretic peptide (ANP), alone or in combination, on tuberoinfundibular dopaminergic (TIDA) neuronal activity and on serum PRL levels were examined in this study. The TIDA neuronal activity was determined by measuring 3,4-dihydroxyphenylacetic acid (DOPAC) concentration in the...

journal_title：Neuroendocrinology

authors： Yen SH,Pan JT

更新日期：1997-11-01 00:00:00

abstract：:The effects of adrenalectomy (ADX) and dexamethasone (DEX) treatment on brain dopamine (DA) receptors of ovariectomized (OVX) rats were investigated by autoradiography using binding of the D1 and D2 antagonists ligands [3H]SCH 23390 and [3H]spiperone, respectively. Fourteen days after ADX, D1 receptors decreased in th...

journal_title：Neuroendocrinology

authors： Biron D,Dauphin C,Di Paolo T

更新日期：1992-04-01 00:00:00

abstract：:The effect of castration and adrenalectomy was studied on vasoactive intestinal peptide (VIP) concentrations in various brain and peripheral structures of male rats. Castration has no effect on any of the structures studied, whereas 4 weeks adrenalectomy (ADX) decreases VIP concentrations in the hippocampus and increa...

journal_title：Neuroendocrinology

authors： Rotsztejn WH,Besson J,Briaud B,Gagnant L,Rosselin G,Kordon C

更新日期：1980-10-01 00:00:00

abstract：:Nontropical rodents have evolved adaptations to maximize winter survival, including alterations in reproduction, energy balance and immunity. Short-day-housed Siberian hamsters display reductions in body fat and decreases in humoral immunity compared with long-day hamsters. The hormone leptin, secreted by adipose tiss...

journal_title：Neuroendocrinology

authors： Demas GE

更新日期：2002-09-01 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) plays a key role in adjusting the basal and stress-activated hypothalamic-pituitary-adrenal axis (HPA). CRH is also widely distributed in extrahypothalamic circuits, where it acts as a neuroregulator to integrate the complex neuroendocrine, autonomic, and behavioral adaptive respo...

journal_title：Neuroendocrinology

authors： Bonfiglio JJ,Inda C,Refojo D,Holsboer F,Arzt E,Silberstein S

更新日期：2011-01-01 00:00:00

abstract：:The effect of glucocorticoids on corticotropin-releasing factor (CRF) gene expression was studied by combination of in situ hybridization histochemistry and steroid implantation. Dexamethasone micropellets, implanted around the hypothalamic paraventricular nucleus (PVN), caused total inhibition of the hybridizable CRF...

journal_title：Neuroendocrinology

authors： Kovács KJ,Mezey E

更新日期：1987-10-01 00:00:00

abstract：:The frequency of pulsatile release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) is high in the breeding season and low in the nonbreeding season. These alterations in the patterns of GnRH and LH release are due to an interaction of daylength and gonadal steroid negative feedback. A vast amount...

journal_title：Neuroendocrinology

authors： Dobbins A,Lubbers LS,Jackson GL,Kuehl DE,Hileman SM

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...

journal_title：Neuroendocrinology

authors： Poletini MO,Kennett JE,McKee DT,Freeman ME

更新日期：2010-01-01 00:00:00

abstract：:Autoradiographic methods were used to study the location of estrogen-concentrating cells in the brain of the female hamster. In the hypothalamus, well-labelled cells were reliably found in the posterior medial preoptic area (MPOA), the anterior hypothalamus (AHA), and the ventromedial (VM), arcuate (ARC) and ventral p...

journal_title：Neuroendocrinology

authors： Krieger MS,Morrell JI,Pfaff DW

更新日期：1976-01-01 00:00:00

abstract：:To elucidate the mechanisms of the impaired pituitary response to growth hormone-releasing hormone (GHRH) in aged animals on a cellular basis, a reverse hemolytic plaque assay was performed on dispersed pituitary cells from young (8-month-old) and old (26-month-old) male F344 rats. The proportion of growth hormone (GH...

journal_title：Neuroendocrinology

authors： Shimokawa I,Higami Y,Okimoto T,Ikeda T

更新日期：1994-12-01 00:00:00

abstract：:The effects of corticotropin-releasing factor (CRF) on GnRH release from the adult male rat mediobasal hypothalamus (MBH) and median eminence (ME) were studied in an in vitro incubation system. CRF induced a dose-related inhibition of GnRH release from both the MBH and the isolated ME, and this inhibition was blocked ...

journal_title：Neuroendocrinology

authors： Gambacciani M,Yen SS,Rasmussen DD

更新日期：1986-01-01 00:00:00

abstract：:The purpose of the present study was to evaluate the opioid receptor subtype mediating opioid modulation of growth hormone (GH) secretion during ontogeny. The mu-agonist morphine and the kappa agonist U50,488 caused a stimulation and inhibition of GH secretion, respectively, on postnatal day 10. Studies on postnatal d...

journal_title：Neuroendocrinology

authors： Eason MG,Francis RS,Kuhn CM

更新日期：1996-06-01 00:00:00

abstract：:Circadian rhythm of blood corticosterone in adrenalectomized rats with (AT rat) or without adrenal autotransplants was investigated. Blood samples were obtained individually at 4-hour intervals for a 24-hour period per week for 5-7 consecutive weeks by the tail tip incision method. Corticosterone responses of the auto...

journal_title：Neuroendocrinology

authors： Murakami N,Takahashi K

更新日期：1982-03-01 00:00:00

abstract：:Arginine-vasopressin (AVP) is regarded as a potent stimulator of pituitary adrenocorticotropin (ACTH) secretion and participates therefore in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis function in concert with the physiological activator of the axis, hypothalamic corticotropin-releasing hormone (C...

journal_title：Neuroendocrinology

authors： Bernardini R,Chiarenza A,Kamilaris TC,Renaud N,Lempereur L,Demitrack M,Gold PW,Chrousos GP

更新日期：1994-11-01 00:00:00

abstract：:To study the eyes' role in maintaining the circadian rhythm in pituitary-adrenal function, 24-h patterns of corticosterone levels were compared in intact and blinded adult female rats. Rats were blinded by optic enucleation at approximately 80 days of age. Nonstress plasma corticosterone levels were determined fluorom...

journal_title：Neuroendocrinology

authors： Wilson MM,Rice RW,Critchlow V

更新日期：1976-01-01 00:00:00

abstract：:Relief of symptoms can be achieved following surgery for growth hormone (GH)-secreting adenomas, as well as after pharmacological therapy with somatostatin analogs. Recently, long-acting somatostatin analog depot formulations, octreotide LAR and lanreotide SR have become available. Somatostatin analogs control GH/insu...

journal_title：Neuroendocrinology

authors： Tolis G,Angelopoulos NG,Katounda E,Rombopoulos G,Kaltzidou V,Kaltsas D,Protonotariou A,Lytras A

更新日期：2006-01-01 00:00:00

abstract：:The accuracy and reproducibility of the World Health Organization (WHO) 2015 classification of bronchopulmonary neuroendocrine neoplasms (BP-NENs) is disputed. The aim of this study is to classify and grade BP-NENs using the WHO 2019 classification of digestive system NENs (DiS-NEN-WHO 2019), and to analyze its accura...

journal_title：Neuroendocrinology

authors： Oka N,Kasajima A,Konukiewitz B,Sakurada A,Okada Y,Kameya T,Weichert W,Ishikawa Y,Suzuki H,Sasano H,Klöppel G

更新日期：2020-01-01 00:00:00

abstract：:In previous studies, we have shown that male Wistar rats exposed to a single inescapable stressor session (15 min restraint) exhibited 24 h later an anxiogenic-like behavior in the elevated plus-maze (EPM), which was reversed by inhibition of corticosterone (CS) synthesis with metyrapone (75 mg/kg i.p.) 3 h before str...

journal_title：Neuroendocrinology

authors： Calvo N,Volosin M

更新日期：2001-04-01 00:00:00

abstract：:In vitro and in vivo perfusion techniques were used to examine the changes in the release of beta-endorphin, methionine-enkephalin (met-enkephalin), dynorphin and luteinizing hormone releasing hormone (LHRH) in response to the corticotropin releasing factor (CRF) receptor antagonist, alpha-helical CRF9-41. All four pe...

journal_title：Neuroendocrinology

authors： Nikolarakis KE,Almeida OF,Sirinathsinghji DJ,Herz A

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors (NETs) are rare and characterized by a heterogeneous clinical course and an unmet need for better prognostic markers. Plasma cell-free DNA (cfDNA) has prognostic value in other malignancies but is not previously investigated in NETs. We studied cfDNA levels in patients with mainly low g...

journal_title：Neuroendocrinology

authors： Oversoe SK,Sorensen BS,Tabaksblat EM,Gronbaek H,Kelsen J

更新日期：2021-01-18 00:00:00

abstract：:Recordings were made of single unit activity through chronically implanted electrodes within the hypothalamic paraventricular nucleus of freely moving male rats also bearing chronically implanted stimulating electrodes in the preoptic area (POA) and indwelling jugular cannulae. High frequency electrical stimulation of...

journal_title：Neuroendocrinology

authors： Saphier D,Feldman S

更新日期：1986-01-01 00:00:00

abstract：:The known occurrence of opiates in the adrenals stimulated us to determine whether Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2), an endogenous peptide that can act as an antiopiate, is present in these glands and whether adrenalectomy affects its concentrations in plasma. The presence of Tyr-MIF-1 in the adrenals of the rat was sh...

journal_title：Neuroendocrinology

authors： Kastin AJ,Fabre L,Banks WA,Zadina JE

更新日期：1993-03-01 00:00:00

abstract：UNLABELLED:Mediobasal hypothalamic slices of adult ovariectomized (OVX) rats treated or not with 17 beta-estradiol (E2) were superfused in buffered (pH 7.2) Locke medium containing bacitracin. A 6-min pulse of K+ (56 m M) was less effective in releasing luteinizing hormone releasing hormone (LH-RH) from mediobasal hypo...

journal_title：Neuroendocrinology

authors： Drouva SV,Laplante E,Gautron JP,Kordon C

更新日期：1984-02-01 00:00:00

abstract：:Somatostatin receptors on lactotroph cells of the anterior pituitary are positively regulated by estradiol. In the present work, we investigated whether estradiol regulation of somatostatin receptors also occurred in the female rat brain. 125I-Tyr0-DTrp8-somatostatin (125I-SRIF: 780 Ci/mM) was used as a ligand. Female...

journal_title：Neuroendocrinology

authors： Slama A,Videau C,Kordon C,Epelbaum J

更新日期：1992-08-01 00:00:00

abstract：:Glucocorticoid hormones have important effects on brain function in the context of acute and chronic stress. Many of these are mediated by the glucocorticoid receptor (GR). GR has transcriptional activity which is highly context-specific and differs between tissues and even between cell types. The outcome of GR-mediat...

journal_title：Neuroendocrinology

authors： Viho EMG,Buurstede JC,Mahfouz A,Koorneef LL,van Weert LTCM,Houtman R,Hunt HJ,Kroon J,Meijer OC

更新日期：2019-01-01 00:00:00

abstract：:G-protein-coupled receptor 135 (GPCR135), a former orphan GPCR also known as SALPR, has recently been shown to be modulated by relaxin-3 (R3). In addition to GPCR135, R3 has been shown to be an agonist for GPCR142 (which is a pseudogene in the rat) and to activate LGR7, which is primarily the receptor for relaxin-1/2....

journal_title：Neuroendocrinology

authors： Sutton SW,Bonaventure P,Kuei C,Roland B,Chen J,Nepomuceno D,Lovenberg TW,Liu C

更新日期：2004-01-01 00:00:00

abstract：:The mechanisms by which leptin influences energy homeostasis are not entirely understood. Several observations indicate that proopiomelanocortin (POMC) is involved in the regulation of food intake and may be a mediator of leptin action. To further study this interaction, a sensitive solution hybridization assay was us...

journal_title：Neuroendocrinology

authors： Korner J,Chua SC Jr,Williams JA,Leibel RL,Wardlaw SL

更新日期：1999-12-01 00:00:00

abstract：:To determine the possible physiological role of endogenous growth hormone-releasing factor (GRF) in the neuronal content and release of cerebral somatostatin (SS), we studied the effect of endogenous GRF blockade on the immunoreactive SS (IR-SS) content of cells and media in fetal rat cerebral cortical and hypothalami...

journal_title：Neuroendocrinology

authors： de los Frailes MT,Cacicedo L,Fernandez G,Tolón RM,Jesus Lorenzo M,Aguado F,Sánchez Franco F

更新日期：1992-02-01 00:00:00