In vivo and in vitro effects of arginine-vasopressin receptor antagonists on the hypothalamic-pituitary-adrenal axis in the rat.

abstract：:In rats anesthetized with sodium pentobarbital, adrenal venous blood samples were collected and analyzed for epinephrine and norepinephrine by the fluorometric method. Stimulation of the inferior fovea or adjacent areas resulted in a significant increase in epinephrine secretion. Stimulation of some other areas of the...

journal_title：Neuroendocrinology

authors： Matsui H

更新日期：1979-01-01 00:00:00

abstract：:Methanol extracts of rat plasma resulted in release of prolactin (PRL) from rat hemipituitaries in vitro with a linear log-dose relationship. This prolactin-releasing factor (PRF)-like activity was not altered in plasma from rats treated with bromocryptine or chlorpromazine despite significant suppression and stimulat...

journal_title：Neuroendocrinology

authors： Garthwaite TL,Hagen TC

更新日期：1979-01-01 00:00:00

abstract：:Concentrations of luteinizing hormone (LH) and prolactin (Prl) in the serum of anestrous and cycling ewes were compared. The concentration of LH in serum and the frequency of episodic releases of LH were lower in anestrous than in cycling ewes. Concentrations of LH in serum rose as rapidly after ovariectomy of anestro...

journal_title：Neuroendocrinology

authors： Jackson GL,Davis SL

更新日期：1979-01-01 00:00:00

abstract：:Cushing's syndrome is associated with serious morbidity and increased mortality. Irrespective of its cause, i.e. a pituitary adenoma, ectopic ACTH production or an adrenal neoplasia, Cushing's syndrome is primarily treated surgically. However, when surgery is unsuccessful or contraindicated, medical therapy is needed ...

journal_title：Neuroendocrinology

authors： Feelders RA,Hofland LJ,de Herder WW

更新日期：2010-01-01 00:00:00

abstract：:It has been recently demonstrated that luteinizing hormone-releasing hormone (LHRH) can inhibit LHRH release by the hypothalamus, suggesting an ultrashort feedback of LHRH on LHRH neurons. In order to test this hypothesis, immunocytochemical localization of LHRH was conducted in the preoptic area of the rat brain. Con...

journal_title：Neuroendocrinology

authors： Pelletier G

更新日期：1987-11-01 00:00:00

abstract：:The pressor effect of intravenous angiotensin II (AII) was compared in the unrestrained rat before and after electrolytic lesions of the subfornical organ (SFO), the circumventricular organ of the dorsal third cerebral ventricle. Abdominal aortic and venal caval catheters were used to measure arterial pressure and to ...

journal_title：Neuroendocrinology

authors： Mangiapane ML,Simpson JB

更新日期：1980-12-01 00:00:00

abstract：:Acute electrolytic stimulation of the median raphe (MR) nucleus (MR Stim) between 13:00 and 16:00 h on proestrus blocked ovulation in 10 of the 21 rats tested, whereas all sham-treated (MR Sham, no current) animals ovulated normally (n = 12). MR Stim at 16:00 h on proestrus in individual cannulated rats 'turned off' t...

journal_title：Neuroendocrinology

authors： Barofsky AL

更新日期：1979-01-01 00:00:00

abstract：:Amygdalotomized, sham-operated and intact wild-derived house mice of both sexes were group-caged (8-10) or singly caged for 3 weeks. The weights of ovaries (p is less than 0.05) and uteri (p is less than 0.01) were less in intact and sham-operated grouped females compared to singly caged intact and amygdalotomized fem...

journal_title：Neuroendocrinology

authors： Pasley JN,Powell EW,Cernosek RM,Cernosek SF

更新日期：1978-01-01 00:00:00

abstract：:Administration of the bovine pineal peptide threonylseryllysine (TSL) to unilaterally ovariectomized (UO) mice as a single intraperitoneal injection on the day of UO reduced the 5-day compensatory ovarian hypertrophy. The same dose of TSL (175 ng/animal) significantly (p less than 0.01) reduced serum follicle stimulat...

journal_title：Neuroendocrinology

authors： Orts RJ,Bruot BC,Sartin JL

更新日期：1980-08-01 00:00:00

abstract：:Adenylate cyclase activity was studied in anterior pituitary homogenates from young adult (6 months) and old (20 and 24 months) male rats. Basal, NaF-, GTP-, 5'-guanylimidodiphosphate (Gpp(NH)p)- and forskolin-stimulated activities were similar in the three groups, implying that the stimulatory guanyl nucleotide regul...

journal_title：Neuroendocrinology

authors： Robberecht P,Gillard M,Waelbroeck M,Camus JC,De Neef P,Christophe J

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIM:Somatostatin (SST) analogs are mainstay for controlling tumor proliferation and hormone secretion in carcinoid patients. Recent data suggest that extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation may potentiate the anti-tumor effects of SST analogs in carcinoids. Additionally, ERK1/2 pho...

journal_title：Neuroendocrinology

authors： Somnay Y,Chen H,Kunnimalaiyaan M

更新日期：2013-01-01 00:00:00

abstract：:An in vitro perifusion system was used to investigate immunoreactive beta-endorphin (beta-END-I) release from adult human hypothalami in response to dopamine (DA) and the DA receptor antagonist haloperidol (HAL). Administration of a 1 microM pulse of DA consistently elicited a mean (+/- SE) 88 +/- 9% increase (p less ...

journal_title：Neuroendocrinology

authors： Rasmussen DD,Liu JH,Wolf PL,Yen SS

更新日期：1987-03-01 00:00:00

abstract：:Reliable prediction of disease status is a major challenge in managing gastroenteropancreatic neuroendocrine tumors (GEP-NET). The aim of the study was to validate the NETest®, a blood molecular genomic analysis, for predicting the course of disease in individual patients compared to Chromogranin A (CgA). NETest® (nor...

journal_title：Neuroendocrinology

authors： van Treijen MJC,van der Zee D,Heeres BC,Staal FCR,Vriens MR,Saveur LJ,Verbeek WHM,Korse CM,Maas M,Valk GD,Tesselaar M

更新日期：2020-06-03 00:00:00

abstract：:The modulatory actions of ovarian steroids on the norepinephrine (NE) induced alterations in luteinizing hormone (LH) secretion were examined in male and female rats. Long-term (4 weeks) castrated male and female rats bearing chronic third-ventricle cannulae were implanted with intra-atrial catheters. Animals were ble...

journal_title：Neuroendocrinology

authors： Condon TP,Handa RJ,Gorski RA,Sawyer CH,Whitmoyer DI

更新日期：1986-01-01 00:00:00

abstract：:The hypothalamic neurons containing substance P (SP) were examined immunohistochemically in rats with a normal estrous cycle or persistent estrus (PE), in pregnancy and in lactating state. In PE animals, the neurons increased in number 1 week after ovariectomy, but then decreased and disappeared. During pregnancy, the...

journal_title：Neuroendocrinology

authors： Tsuruo Y,Hisano S,Nakanishi J,Katoh S,Daikoku S

更新日期：1987-05-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:High affinity binding of 3H-flunitrazepam (FNZP) to crude membrane preparations of bovine pineal membranes was examined by a rapid filtration procedure through Whatman GFB paper. At 0 degrees C binding reached equilibrium in about 20 min. Scatchard analysis of data at equilibrium revealed a single population of bindin...

journal_title：Neuroendocrinology

authors： Lowenstein PR,Cardinali DP

更新日期：1983-08-01 00:00:00

abstract：:Previous studies have shown that the stimulation of LH release by the opiate receptor blocker, naloxone, can be prevented by catecholamine synthesis inhibitors, suggesting opiate regulation of catecholamine release. The present study tested whether an opiate agonist and antagonist would affect the depletion of hypotha...

journal_title：Neuroendocrinology

authors： Adler BA,Crowley WR

更新日期：1984-03-01 00:00:00

abstract：:Pituitary oxytocin (OT) secretion is inversely related to saline consumption in several experimental models of sodium appetite in rats. Because systemic OT administration does not inhibit sodium appetite, release of OT as a neurotransmitter within the brain, coincident with its secretion from the pituitary, may be rel...

journal_title：Neuroendocrinology

authors： Blackburn RE,Stricker EM,Verbalis JG

更新日期：1992-08-01 00:00:00

abstract：:The obese gene (OB) product, leptin, has been shown to exert control on metabolic processes such as food intake and body weight homeostasis, possibly through a neuropeptide Y (NPY) neurotransmission. More recently, leptin has been shown to control several neuroendocrine axes, modulating pituitary hormone secretions in...

journal_title：Neuroendocrinology

authors： Vuagnat BA,Pierroz DD,Lalaoui M,Englaro P,Pralong FP,Blum WF,Aubert ML

更新日期：1998-05-01 00:00:00

abstract：:Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

journal_title：Neuroendocrinology

authors： Lytras A,Tolis G

更新日期：2006-01-01 00:00:00

abstract：:We have studied some of the neuroendocrine and social correlates of dexamethasone resistance in a nonhuman primate population. Subjects were 51 male Macaca fascicularis monkeys with known behavioral histories and who had been given dexamethasone (DEX) suppression tests a week prior to killing. We compared the subset o...

journal_title：Neuroendocrinology

authors： Brooke SM,de Haas-Johnson AM,Kaplan JR,Manuck SB,Sapolsky RM

更新日期：1994-08-01 00:00:00

abstract：:Characteristic increases in neuronal activity coincident with the pulsatile release of luteinizing hormone from the pituitary gland have been recorded from electrodes chronically implanted in the medial basal hypothalamus of the rhesus monkey. This electrophysiologic manifestation of the hypothalamic 'pulse generator'...

journal_title：Neuroendocrinology

authors： Wilson RC,Kesner JS,Kaufman JM,Uemura T,Akema T,Knobil E

更新日期：1984-09-01 00:00:00

abstract：:The effect of in vivo corticosterone manipulation on binding sites for the excitatory neurotransmitter glutamate was determined using radioligand binding to rat brain cryostat sections and crude synaptic membranes. 3H-glutamate binding to regions of the dorsal hippocampal formation was significantly decreased in adren...

journal_title：Neuroendocrinology

authors： Halpain S,McEwen BS

更新日期：1988-09-01 00:00:00

abstract：:This study compares the processing of pro-opiomelanocortin (POMC) at two Lys-Lys cleavage sites, located in the carboxy-terminal domain of the precursor, one site marking the amino terminus of beta-melanocyte-stimulating hormone (beta-MSH) and the other in the carboxy-terminus of beta-endorphin (beta E). These compari...

journal_title：Neuroendocrinology

authors： Lin HL,Day NC,Ueda Y,Martin DK,Dixon JE,Seidah NG,Akil H

更新日期：1993-07-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:The mechanisms by which leptin influences energy homeostasis are not entirely understood. Several observations indicate that proopiomelanocortin (POMC) is involved in the regulation of food intake and may be a mediator of leptin action. To further study this interaction, a sensitive solution hybridization assay was us...

journal_title：Neuroendocrinology

authors： Korner J,Chua SC Jr,Williams JA,Leibel RL,Wardlaw SL

更新日期：1999-12-01 00:00:00

abstract：:Met-enkephalin concentrations in the anterior pituitary gland were shown to decline dramatically within the first 24 h after reserpine treatment, with effects apparent as early as 6 h. This was followed by subsequent repletion and late augmentation of Met-enkephalin levels 3 weeks following reserpine. Treatment with t...

journal_title：Neuroendocrinology

authors： George SR,Kertesz M

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND/AIMS:A mammalian circannual pacemaker responsible for regulating the seasonal pattern of prolactin has been recently described in sheep. This pacemaker resides within the pars tuberalis, an area of the pituitary gland that densely expresses melatonin receptors. However, the chemical identity of the cell type...

journal_title：Neuroendocrinology

authors： Hodson DJ,Townsend J,Tortonese DJ

更新日期：2013-01-01 00:00:00