The corticotropin-releasing hormone network and the hypothalamic-pituitary-adrenal axis: molecular and cellular mechanisms involved.

abstract：:We have attempted to elucidate the effect of glucose concentrations on the release of thyrotropin-releasing hormone (TRH), a brain neuropeptide possessing glucoregulatory function, from rat hypothalamic slices in vitro. Rat hypothalamic slices were preincubated for 60 min at 37 degrees C in Krebs-Ringer bicarbonate (K...

journal_title：Neuroendocrinology

authors： Yamaguchi M,Iriuchijima T,Michimata T,Mori M

更新日期：1991-04-01 00:00:00

abstract：:To assess the neuroendocrine correlates of menstrual status migrainosus (MSM) and menstrual migraine (MM), we evaluated the prolactin (PRL) and cortisol responses to the direct central serotoninergic (5-HT) agonist meta-chlorophenylpiperazine (m-CPP) administered orally (0.5 mg/kg) during the follicular (FP: +6, +8) a...

journal_title：Neuroendocrinology

authors： Nappi RE,Sances G,Brundu B,Ghiotto N,Detaddei S,Biancardi C,Polatti F,Nappi G

更新日期：2003-07-01 00:00:00

abstract：:We have examined the effect of electrical stimulation in the subfornical organ (SFO) on the activity of neurons in the medial septum and diagonal band of Broca (MS-DBB) which project to the median eminence in the rat. Previous studies have suggested that septal neurons with such projections are luteinizing hormone rel...

journal_title：Neuroendocrinology

authors： Donevan SD,Ferguson AV

更新日期：1988-07-01 00:00:00

abstract：:Gastric carcinoids are rare neuroendocrine tumors, usually classified as type I, if associated with atrophic body gastritis; type II, if associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type I, and type III, in the absence of any gastric pathology (sporadic tumors). The pathological features...

journal_title：Neuroendocrinology

authors： Delle Fave G,Capurso G,Annibale B,Panzuto F

更新日期：2004-01-01 00:00:00

abstract：:The influence of catecholamines (CA) on hypothalamic somatostatin (HPT-SRIF) was investigated in rats by using several drugs which interfere with brain CA metabolism. Depletion of brain CA stores by alpha-methyl-rho-tyrosine (AMT) increased HPT-SRIF, while augmented brain CA levels following L-dopa administration decr...

journal_title：Neuroendocrinology

authors： Torres I,Guaza C,Fernandez-Durango R,Borrell J,Charro AL

更新日期：1982-01-01 00:00:00

abstract：:The ligand specificities of sites binding tritium-labeled arginine vasopressin (3H-AVP) were investigated in membrane preparations of rat anterior pituitary gland and liver. Labeled AVP interacted with high-affinity, low-capacity binding sites in liver as well as in pituitary membrane fractions. Binding displacement s...

journal_title：Neuroendocrinology

authors： Antoni FA

更新日期：1984-08-01 00:00:00

abstract：:The distribution of gamma-aminobutyric acid (GABA) nerve fibers and cell bodies in the rat hypothalamus and pituitary gland was immunohistochemically examined using antibodies against the GABA-synthesizing enzyme glutamate decarboxylase (GAD). The dense network of GAD-positive nerve fibers was observed to be essential...

journal_title：Neuroendocrinology

authors： Vincent SR,Hökfelt T,Wu JY

更新日期：1982-02-01 00:00:00

abstract：:Substance P (SP) is known to act on pituitary hormone release either at the hypothalamic level or directly at the pituitary level. In order to investigate whether SP is present in the pituitary gland and to localize the peptide at the cellular and subcellular levels, the immunocytological method was used. Rat pituitar...

journal_title：Neuroendocrinology

authors： Morel G,Chayvialle JA,Kerdelhue B,Dubois PM

更新日期：1982-01-01 00:00:00

abstract：:Plasma TSH responses after an i.v. injection of 100 mg of L-dopa were evaluated by radioimmunoassay in 4 normal euthyroid subjects and in 8 patients with primary hypothyroidism. In agreement with previous results, no variations to plasma TSH levels were observed in the euthyroid subjects. In contrast, in primary hypo...

journal_title：Neuroendocrinology

authors： Minozzi M,Faggiano M,Lombardi G,Carella C,Criscuolo T,Scapagnini U

更新日期：1975-01-01 00:00:00

abstract：:Blood samples were removed via chronic intra-atrial cannulae every 15 min in female rats during the estrous cycle, the last week of pregnancy, parturition and suckling. Growth hormone (GH) secretion during the estrous cycle is characterized by episodic release, occurring approximately once hourly. The surges in GH inc...

journal_title：Neuroendocrinology

authors： Saunders A,Terry LC,Audet J,Brazeau P,Martin JB

更新日期：1976-01-01 00:00:00

abstract：:An influence of thyroid status on the secretory activity of hypothalamic dopaminergic neurons was observed in adult rats and its involvement in the regulation of prolactin (PRL) secretion was examined. The secretory activity of the tuberoinfundibular dopaminergic (TIDA) neurons was evaluated by measurement of dopamine...

journal_title：Neuroendocrinology

authors： Reymond MJ,Benotto W,Lemarchand-Béraud T

更新日期：1987-06-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:The effect of sonicated suspensions of phosphatidylserine (PS), an acidic phospholipid, was investigated on prolactin secretion utilizing in vivo and in vitro approaches. Acute and chronic administration of PS reduced plasma prolactin levels during different phases of circadian rhythms. The phospholipid was able to in...

journal_title：Neuroendocrinology

authors： Canonico PL,Annunziato L,Toffano G,Bernardini R,Stanzani S,Foti M,Clementi G,Drago F,Scapagnini U

更新日期：1981-12-01 00:00:00

abstract：:The neurotransmitter and andrenoceptors involved in the inhibition of luteinizing hormone (LH) release induced by stimulating the locus ceruleus nucleus (LC) have been characterized in ovariectomized, estrogen-primed rats in which the release of LH was triggered by electrical stimulation of the medial preoptic area. B...

journal_title：Neuroendocrinology

authors： Dotti C,Taleisnik S

更新日期：1984-01-01 00:00:00

abstract：:Molecules of astrocyte origin influence gonadotropin-releasing hormone (GnRH) release and GnRH neuronal growth and differentiation. Furthermore, type 1 astrocytes express steroid receptors, presenting the possibility that steroid actions on GnRH neurons might occur via astrocytes. Utilizing GT1-7 cells, a GnRH-secreti...

journal_title：Neuroendocrinology

authors： Zwain IH,Arroyo A,Amato P,Yen SS

更新日期：2002-06-01 00:00:00

abstract：:There is extensive evidence that serotonin (5-HT) is implicated in the neuroendocrine control regulating the secretion of several anterior pituitary hormones. It has also been reported that the posterior pituitary is necessary for prolactin (PRL) response to 5-HT as well as to suckling, in which 5-HT implication has b...

journal_title：Neuroendocrinology

authors： Balsa JA,Sánchez-Franco F,Pazos F,Lara JI,Lorenzo MJ,Maldonado G,Cacicedo L

更新日期：1998-11-01 00:00:00

abstract：:Pathologies involving the pituitary stalk (PS) are generally revealed by the presence of diabetes insipidus. The availability of MRI provides a major diagnostic contribution by enabling the visualization of the site of the culprit lesion, especially when it is small. However, when only an enlarged PS is found, the eti...

journal_title：Neuroendocrinology

authors： Hána V,Salenave S,Chanson P

更新日期：2020-01-01 00:00:00

abstract：:In the Siberian hamster the pituitary content of bioassayable MSH has been shown to be seasonally variable, being greater during the long days of spring and summer than during the short days of autumn and winter. Similar changes in the pituitary content of both bioassayable MSH and immunoreactive alpha MSH can be indu...

journal_title：Neuroendocrinology

authors： Logan A,Weatherhead B

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...

journal_title：Neuroendocrinology

authors： Poletini MO,Kennett JE,McKee DT,Freeman ME

更新日期：2010-01-01 00:00:00

abstract：:The hypothalamic GnRH pulse generator activity, which was assessed by the characteristic increases in the multiple unit activity (MUA) specifically associated with the pulsatile LH secretion (MUA volleys), was monitored throughout the estrous cycle of the female goat. Blood samples were collected daily for analysis of...

journal_title：Neuroendocrinology

authors： Tanaka T,Ozawa T,Hoshino K,Mori Y

更新日期：1995-12-01 00:00:00

abstract：:Using specific antibodies to corticotrophin-releasing factor (CRF) and arginine vasopressin (AVP) we have immunocytochemically located cells and fibres containing these peptides in sheep fetuses. CRF neurones were first detected, in low frequency, in the paraventricular nuclei of fetuses of 90 days of gestation (term ...

journal_title：Neuroendocrinology

authors： Levidiotis M,Oldfield B,Wintour EM

更新日期：1987-11-01 00:00:00

abstract：:The possible role of prostaglandins (PGs) in the hypothalamic control of ovulation has been investigated by studying the effects of indomethacin (ID) and PGs on the release of luteinizing hormone-releasing hormone (LHRH) from hypothalamic synaptosomes. Female rats were chronically pretreated with ID on diestrus 2 (D2)...

journal_title：Neuroendocrinology

authors： Linton EA,Bennett GW,Whitehead SA

更新日期：1979-01-01 00:00:00

abstract：:This study was carried out to clarify the central effects of neuropeptide Y (NPY) on gonadotropin and prolactin (PRL) release in the male rat and to evaluate the hypothesis that it may play a role in negative feedback regulation of gonadotropin secretion in the male. NPY (4 micrograms in 2 microliters 0.9% NaCl) or an...

journal_title：Neuroendocrinology

authors： Reznikov AG,McCann SM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Type I gastric carcinoids (TIGCs) are neuroendocrine neoplasms arising from enterochromaffin-like cells in atrophic body gastritis. Data regarding their evolution in prospective series are scarce, thus treatment and follow-up are not codified. Our aim was to evaluate clinical outcome and recurrence in TIGCs ...

journal_title：Neuroendocrinology

authors： Merola E,Sbrozzi-Vanni A,Panzuto F,D'Ambra G,Di Giulio E,Pilozzi E,Capurso G,Lahner E,Bordi C,Annibale B,Delle Fave G

更新日期：2012-01-01 00:00:00

abstract：:Distribution and properties of receptors for gonadotropin-releasing hormone (GnRH) were analyzed in the brain of adult male rats. Binding of the iodinated GnRH agonist Des-Gly10-(D-Ala6)-GnRH ethylamide was studied in hippocampus and anterior pituitary using three convergent approaches: quantitative autoradiography on...

journal_title：Neuroendocrinology

authors： Leblanc P,Crumeyrolle M,Latouche J,Jordan D,Fillion G,L'Heritier A,Kordon C,Dussaillant M,Rostène W,Haour F

更新日期：1988-11-01 00:00:00

abstract：:Studies were undertaken to investigate the nature of receptors involved in the prolactin-releasing action of histamine in male rats. The increase of plasma prolactin levels induced by third-ventricle injection of histamine was blocked by intraventricular injection of ranitidine, an H2-antagonist, but not by systemic a...

journal_title：Neuroendocrinology

authors： Donoso AO,Zárate MB,Seltzer A

更新日期：1983-06-01 00:00:00

abstract：:Hypertension in male and aging female rodents is associated with glutamate-dependent plasticity in the hypothalamus, but existing models have failed to capture distinct transitional menopausal phases that could have a significant impact on the synaptic plasticity and emergent hypertension. In rodents, accelerated ovar...

journal_title：Neuroendocrinology

authors： Marques-Lopes J,Tesfaye E,Israilov S,Van Kempen TA,Wang G,Glass MJ,Pickel VM,Iadecola C,Waters EM,Milner TA

更新日期：2017-01-01 00:00:00

abstract：:To determine whether the inhibitory effect of clonidine (CLON) on renin secretion is due in part to a direct action on the kidneys or due entirely to an action on the brain, the drug was administered intravenously in a dose of 30 microgram/kg to dogs in which the spinal cord had been transected in the cervical region....

journal_title：Neuroendocrinology

authors： Ganong WF,Wise BL,Reid IA,Holland J,Kaplan S,Shackelford R,Boryczka AT

更新日期：1978-01-01 00:00:00

abstract：:Acute electrolytic stimulation of the median raphe (MR) nucleus (MR Stim) between 13:00 and 16:00 h on proestrus blocked ovulation in 10 of the 21 rats tested, whereas all sham-treated (MR Sham, no current) animals ovulated normally (n = 12). MR Stim at 16:00 h on proestrus in individual cannulated rats 'turned off' t...

journal_title：Neuroendocrinology

authors： Barofsky AL

更新日期：1979-01-01 00:00:00