Gastric neuroendocrine tumors.

abstract：:A prolactin (PRL) surge occurs in the female rat during proestrus in response to elevated estradiol levels. The elevated release of ovarian steroids on the day of proestrus is also associated with sexual receptivity. Mating triggers twice-daily PRL surges that supplant the proestrous PRL surge and are responsible for ...

journal_title：Neuroendocrinology

authors： Yang S,Lee Y,Voogt JL

更新日期：1999-04-01 00:00:00

abstract：:alpha-Methyl-p-tyrosine (alpha-MT), a competitive inhibitor of tyrosine hydroxylase, was used to block the synthesis of hypothalamic catecholamines in immature female rats of 14, 16 and 30 days of age and in castrated adults. The administration of alpha-MT (300 mg/kg body weight, free base) induced a significant decay...

journal_title：Neuroendocrinology

authors： Moguilevsky JA,Arias P,Szwarcfarb B,Carbone S,Rondina D

更新日期：1990-10-01 00:00:00

abstract：:Interactions between the hypothalamic-pituitary-adrenocortical (HPA) system and melatonin secretion have been demonstrated, but only the effects of melatonin on the activity of the HPA system have been studied in man. Alterations of melatonin secretion described as low-melatonin syndrome have been demonstrated in pati...

journal_title：Neuroendocrinology

authors： Kellner M,Yassouridis A,Manz B,Steiger A,Holsboer F,Wiedemann K

更新日期：1997-04-01 00:00:00

abstract：:Previous work in many laboratories has shown that luteinizing hormone-releasing hormone (LHRH) neurons display a range of shapes from smooth-contoured to extremely irregular or 'thorny'. To determine if these forms reflect or can be modified by the gonadal steroid milieu, the morphology of LHRH neurons was examined in...

journal_title：Neuroendocrinology

authors： Witkin JW

更新日期：1989-04-01 00:00:00

abstract：:Peptidyl-glycine alpha-amidation activity has been detected in human cerebrospinal fluid (CSF) and in several regions of the central nervous system. Activity was monitored by measuring conversion of mono-125I-D-Tyr-Val-Gly into mono-125I-D-Tyr-Val-NH2. The alpha-amidation activity in CSF is dependent on molecular oxyg...

journal_title：Neuroendocrinology

authors： Wand GS,Ney RL,Mains RE,Eipper BA

更新日期：1985-12-01 00:00:00

abstract：:We studied the effects of selected leukotrienes and hydroxyeicosatetraenoic acids (HETEs) on prolactin release from primary cultures of female rats anterior pituitary cells. Leukotrienes B4, C4, and D4 had no effect on basal prolactin release; however, they did enhance prolactin release that was stimulated by 1 or 5 n...

journal_title：Neuroendocrinology

authors： Judd AM,Spangelo BL,Ehreth JT,MacLeod RM

更新日期：1988-10-01 00:00:00

abstract：:Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...

journal_title：Neuroendocrinology

authors： Terracciano F,Capone A,Montori A,Rinzivillo M,Partelli S,Panzuto F,Pilozzi E,Arcidiacono PG,Sette C,Capurso G

更新日期：2020-07-02 00:00:00

abstract：:The capability of the anterior pituitary gland to secrete growth hormone (GH) in response to an intravenous injection of growth hormone-releasing factor, hpGRF-44, was evaluated in male rats ranging from 22 days to 24 months of age. The increase in GH concentrations following a submaximal dose of hpGRF-44 (0.5 microgr...

journal_title：Neuroendocrinology

authors： Wehrenberg WB,Ling N

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Little information is available concerning prognostic factors for bronchopulmonary large cell neuroendocrine carcinomas (BP-LCNECs) and even less is known about combined LCNECs (Co-LCNECs). We investigated whether an integrated morphological, immunohistochemical, and molecular approach could be used for thei...

journal_title：Neuroendocrinology

authors： Milione M,Maisonneuve P,Grillo F,Mangogna A,Centonze G,Prinzi N,Pusceddu S,Garzone G,Cattaneo L,Busico A,Bossi P,Spaggiari P,Pellegrinelli A,Del Gobbo A,Ferrero S,Kankava K,Pruneri G,Rolli L,Roca E,Bercich L,Tiron

更新日期：2020-05-04 00:00:00

abstract：:Thyroid hormones and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling play a significant role in the structural development of the cerebellum, respectively. In the present study, the possible contribution of neuronal NO synthase (NOS) and cGMP in the thyroid hormone-induced structural changes was invest...

journal_title：Neuroendocrinology

authors： Serfozo Z,de Vente J,Elekes K

更新日期：2009-01-01 00:00:00

abstract：:Interleukin-1 (IL-1) and glucocorticoid hormones represent two key mediators involved in the modulation of the neuroimmunoendocrine response to stress. IL-1 is a potent activator of the hypothalamic-pituitary-adrenal (HPA) axis in rodents. In the immune system, glucocorticoids modulate IL-1 production and a number of ...

journal_title：Neuroendocrinology

authors： Betancur C,Lledo A,Borrell J,Guaza C

更新日期：1994-02-01 00:00:00

abstract：:The differences in plasma prolactin concentration between normal and estradiol-implanted male rats were compared after treatment with 3 different stimulating agents of prolactin secretion [ether anesthesia, pimozide (a "specific' dopaminergic receptor blocking agent) and TRH] using conscious, free-moving rats implante...

journal_title：Neuroendocrinology

authors： Piercy M,Shin SH

更新日期：1980-10-01 00:00:00

abstract：:Single rat neurohypophyses were impaled on a platinum electrode, perifused with isotonic medium and fractions of perifusate collected each minute. Arginine vasopressin content of the fractions was measured by radioimmunoassay. The basal release of arginine vasopressin varied from 50 to 350 pg (0.02-0.14 mU/min) betwee...

journal_title：Neuroendocrinology

authors： Bicknell RJ,Leng G

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND/AIM:Somatostatin (SST) analogs are mainstay for controlling tumor proliferation and hormone secretion in carcinoid patients. Recent data suggest that extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation may potentiate the anti-tumor effects of SST analogs in carcinoids. Additionally, ERK1/2 pho...

journal_title：Neuroendocrinology

authors： Somnay Y,Chen H,Kunnimalaiyaan M

更新日期：2013-01-01 00:00:00

abstract：:Estradiol rapidly regulates the activity of arcuate nucleus (ARH) proopiomelanocortin (POMC) neurons that project to the medial preoptic nucleus (MPN) to regulate lordosis. Orphanin FQ/nociceptin (OFQ/N) acts via opioid receptor-like (ORL)-1 receptors to inhibit these POMC neurons. Therefore, we tested the hypothesis ...

journal_title：Neuroendocrinology

authors： Conde K,Meza C,Kelly MJ,Sinchak K,Wagner EJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The chemotherapy for small-cell lung carcinoma (SCLC) has been adopted for advanced extrapulmonary neuroendocrine carcinomas (EP-NECs). The aim of this study was to clarify the efficacy of standard SCLC regimens when used to treat EP-NECs and to compare the outcome with that for SCLC. METHODS:We reviewed th...

journal_title：Neuroendocrinology

authors： Terashima T,Morizane C,Hiraoka N,Tsuda H,Tamura T,Shimada Y,Kaneko S,Kushima R,Ueno H,Kondo S,Ikeda M,Okusaka T

更新日期：2012-01-01 00:00:00

abstract：:A number of neurochemical messengers have been shown to act directly on the melanotrope cells of the pars intermedia of Xenopus laevis to regulate alpha MSH secretion. In the present study the possibility that the melanotropes are also indirectly controlled has been examined. For this purpose, the characteristics of a...

journal_title：Neuroendocrinology

authors： de Koning HP,Jenks BG,Scheenen WJ,de Rijk EP,Caris RT,Roubos EW

更新日期：1991-07-01 00:00:00

abstract：:An influence of thyroid status on the secretory activity of hypothalamic dopaminergic neurons was observed in adult rats and its involvement in the regulation of prolactin (PRL) secretion was examined. The secretory activity of the tuberoinfundibular dopaminergic (TIDA) neurons was evaluated by measurement of dopamine...

journal_title：Neuroendocrinology

authors： Reymond MJ,Benotto W,Lemarchand-Béraud T

更新日期：1987-06-01 00:00:00

abstract：:The level of thyroid hormone in blood has been acutely decreased by about 20--30% within 20 min with the aid of isovolemic exchange transfusion (IET) of thyroid hormone free blood cell suspension (THFBCS) in three groups of rats: (1) intact control (C); (2) median eminence (ME)-lesioned; (3) thalamus (TH)-lesioned. Th...

journal_title：Neuroendocrinology

authors： Langer P,Földes O,Mess B,Kokesová H,Gschwendtová K

更新日期：1977-01-01 00:00:00

abstract：:The caudal portion of the spinal cord of elasmobranch fish incorporates a diffuse neuroendocrine system. Using an antiserum raised against urotensin II from a teleost fish (goby) to facilitate purification, a peptide structurally related to urotensin II was isolated in pure form from an extract of neuroendocrine tissu...

journal_title：Neuroendocrinology

authors： Conlon JM,O'Harte F,Smith DD,Balment RJ,Hazon N

更新日期：1992-02-01 00:00:00

abstract：:Hypophysectomized male rats with adenohypophyses grafted under the kidney capsule (HG rat) for 3 weeks with or without estradiol implantation, were used to examine prolactin (PRL) secretion independent of hypothalamic influence. Changes in the circulating PRL concentration were monitored by taking blood samples every ...

journal_title：Neuroendocrinology

authors： Shin SH,Reifel CW

更新日期：1981-03-01 00:00:00

abstract：:Immobilization of adult male rats resulted in concomitant, significant releases of prolactin (PRL) and oxytocin (OT). Naloxone (0.2 mg/kg, i.p.) administration 30 min prior to initiation of restraint resulted in a significant diminution of the PRL response to stress. On the other hand, a significant augmentation of OT...

journal_title：Neuroendocrinology

authors： Samson WK,McDonald JK,Lumpkin MD

更新日期：1985-01-01 00:00:00

abstract：:Knowledge of specific neurotransmitters as well as the pathways and mechanisms regulating appetite in ruminants that continually graze, such as sheep, is incomplete. Although fundamentally agouti-related protein (AGRP) has a similar function across species to increase food intake, the regulation of AGRP may vary acros...

journal_title：Neuroendocrinology

authors： Wagner CG,McMahon CD,Marks DL,Daniel JA,Steele B,Sartin JL

更新日期：2004-01-01 00:00:00

abstract：:Pathologies involving the pituitary stalk (PS) are generally revealed by the presence of diabetes insipidus. The availability of MRI provides a major diagnostic contribution by enabling the visualization of the site of the culprit lesion, especially when it is small. However, when only an enlarged PS is found, the eti...

journal_title：Neuroendocrinology

authors： Hána V,Salenave S,Chanson P

更新日期：2020-01-01 00:00:00

abstract：:The pituitary-adrenal axis is known to be stimulated during the acute-phase response. As cytokines play a central role in mediating the constellation of host response occurring during the acute-phase response it was of interest to assess the ability of cytokines to stimulate ACTH secretion from normal pituitary cells ...

journal_title：Neuroendocrinology

authors： Kehrer P,Turnill D,Dayer JM,Muller AF,Gaillard RC

更新日期：1988-08-01 00:00:00

abstract：:Vasopressin and oxytocin modulate memory processes which effects are dissociated from the typical peripheral endocrine effects of these neuropeptides. Recently, vasopressin has been implicated in the regulation of body temperature. In view of this, experiments were designed to determine whether the antipyretic effect ...

journal_title：Neuroendocrinology

authors： Kovács GL,De Wied D

更新日期：1983-10-01 00:00:00

abstract：:Met-enkephalin concentrations in the anterior pituitary gland were shown to decline dramatically within the first 24 h after reserpine treatment, with effects apparent as early as 6 h. This was followed by subsequent repletion and late augmentation of Met-enkephalin levels 3 weeks following reserpine. Treatment with t...

journal_title：Neuroendocrinology

authors： George SR,Kertesz M

更新日期：1988-02-01 00:00:00

abstract：:Pregnant rats were kept on an ethanol-containing (6% w/v) liquid diet from the 13th day of gestation and serum growth hormone (GH) levels were determined in the offspring after four different experimental paradigms. In controls, administration of cyproheptadine (a serotonin-blocking agent), or insulin, or exposure to ...

journal_title：Neuroendocrinology

authors： Thadani PV

更新日期：1984-04-01 00:00:00

abstract：:Plasma and hypothalamic LHRH was measured by specific radioimmuno-assay in intact and ovariectomized rats, and the values were correlated with peripheral plasma (PP) FSH and LH titers. At most stages of the estrous cycle, plasma LHRH was either undetectable or present at very minimal values. An increase in PP LHRH con...

journal_title：Neuroendocrinology

authors： Wheaton JE,McCann SM

更新日期：1976-01-01 00:00:00

abstract：:Pulsatile gonadotropin-releasing hormone (GnRH) release from the median eminence is critical for the appropriate function of the pituitary gonadotropes and for the generation of a preovulatory gonadotropin surge. The mechanisms by which many GnRH axon terminals are synchronized to release GnRH in a coordinated fashion...

journal_title：Neuroendocrinology

authors： Hosny S,Jennes L

更新日期：1998-02-01 00:00:00