Comparison of chemotherapeutic treatment outcomes of advanced extrapulmonary neuroendocrine carcinomas and advanced small-cell lung carcinoma.

abstract：:Previous studies have shown that prepubertal olfactory bulbectomy will prevent the testicular regression associated with short photoperiod in golden hamsters. The gonadal regression which normally occurs in hamsters on short photoperiod is known to be due in part to an increased responsiveness of the reproductive neur...

journal_title：Neuroendocrinology

authors： Pieper DR,Unthank PD,Shuttie DA,Lobocki CA,Swann JM,Newman S,Subramanian MG

更新日期：1987-10-01 00:00:00

abstract：:The distribution of gamma-aminobutyric acid (GABA) nerve fibers and cell bodies in the rat hypothalamus and pituitary gland was immunohistochemically examined using antibodies against the GABA-synthesizing enzyme glutamate decarboxylase (GAD). The dense network of GAD-positive nerve fibers was observed to be essential...

journal_title：Neuroendocrinology

authors： Vincent SR,Hökfelt T,Wu JY

更新日期：1982-02-01 00:00:00

abstract：:Neuroendocrine mechanisms governing growth hormone (GH) secretion are sensitive to nutritional status since the normal pulsatile pattern of GH release is disrupted during conditions of food deprivation or malnutrition. A reasonable hypothesis for this occurrence is the alteration of somatostatin and GH-releasing hormo...

journal_title：Neuroendocrinology

authors： Brogan RS,Fife SK,Conley LK,Giustina A,Wehrenberg WB

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. AIM:To evaluate the clinicopathological features and therapeutic outcomes of CP diagnosed in the elderly. PATIENTS AND METHODS:A retrospective, multicenter, national study of C...

journal_title：Neuroendocrinology

authors： Iglesias P,Nocete I,Moure Rodríguez MD,Venegas-Moreno E,Ares J,Biagetti B,Rodríguez Berrocal V,Guerrero-Pérez F,Vicente A,Villar-Taibo R,Cordido F,Paja M,Glerean M,González Rivera N,Dios Fuentes E,Blanco C,Alvaréz-Escolá

更新日期：2020-10-09 00:00:00

abstract：:In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

journal_title：Neuroendocrinology

authors： Clark M,Smith MA,Weiss SR,Post RM

更新日期：1994-05-01 00:00:00

abstract：:To determine whether the inhibitory effect of clonidine (CLON) on renin secretion is due in part to a direct action on the kidneys or due entirely to an action on the brain, the drug was administered intravenously in a dose of 30 microgram/kg to dogs in which the spinal cord had been transected in the cervical region....

journal_title：Neuroendocrinology

authors： Ganong WF,Wise BL,Reid IA,Holland J,Kaplan S,Shackelford R,Boryczka AT

更新日期：1978-01-01 00:00:00

abstract：:To characterize the short-term ACTH secretion pattern and to investigate factors regulating it, pituitary venous (PV) blood was collected using our nonsurgical method from 8 unperturbed horses every 20 or 30 s for approximately 1 h. In all but 1 horse, sampling occurred during the broad circadian maximum in plasma cor...

journal_title：Neuroendocrinology

authors： Alexander SL,Irvine CH,Donald RA

更新日期：1994-09-01 00:00:00

abstract：:The effects of intracerebroventricularly (i.c.v.) injected interleukin-1 beta (IL-1 beta: 1, 2.5, 10, and 25 ng) were studied on plasma growth hormone (GH) and prolactin (PRL) concentrations in freely moving rats chronically implanted with i.c.v. cannulas and intracardial catheters. Significant changes in PRL secretio...

journal_title：Neuroendocrinology

authors： Payne LC,Obal F Jr,Opp MR,Krueger JM

更新日期：1992-07-01 00:00:00

abstract：:This study compares the processing of pro-opiomelanocortin (POMC) at two Lys-Lys cleavage sites, located in the carboxy-terminal domain of the precursor, one site marking the amino terminus of beta-melanocyte-stimulating hormone (beta-MSH) and the other in the carboxy-terminus of beta-endorphin (beta E). These compari...

journal_title：Neuroendocrinology

authors： Lin HL,Day NC,Ueda Y,Martin DK,Dixon JE,Seidah NG,Akil H

更新日期：1993-07-01 00:00:00

abstract：:In the present study the effects of intravenously administered corticotropin-releasing hormone (CRH) on the release of proopiomelanocortin (POMC) derivatives such as adrenocorticotropic hormone (ACTH), beta-lipotropin (beta-LPH) and beta-endorphin (beta-END) as well as direct effects of CRH on pain sensitivity were ex...

journal_title：Neuroendocrinology

authors： Matejec R,Uhlich H,Hotz C,Mühling J,Harbach HW,Bödeker RH,Hempelmann G,Teschemacher H

更新日期：2005-01-01 00:00:00

abstract：:The effect of castration and adrenalectomy was studied on vasoactive intestinal peptide (VIP) concentrations in various brain and peripheral structures of male rats. Castration has no effect on any of the structures studied, whereas 4 weeks adrenalectomy (ADX) decreases VIP concentrations in the hippocampus and increa...

journal_title：Neuroendocrinology

authors： Rotsztejn WH,Besson J,Briaud B,Gagnant L,Rosselin G,Kordon C

更新日期：1980-10-01 00:00:00

abstract：:The sheep exhibits a marked sex difference in the timing of the pubertal increase in luteinizing hormone (LH). Male lambs undergo a reduction in sensitivity to inhibitory steroid feedback, leading to an increase in LH by 10 weeks of age, but females remain hypersensitive until 30 weeks of age. Endogenous opioids suppr...

journal_title：Neuroendocrinology

authors： Wood RI,I'Anson H,Ebling FJ,Foster DL

更新日期：1992-12-01 00:00:00

abstract：:Reliable prediction of disease status is a major challenge in managing gastroenteropancreatic neuroendocrine tumors (GEP-NET). The aim of the study was to validate the NETest®, a blood molecular genomic analysis, for predicting the course of disease in individual patients compared to Chromogranin A (CgA). NETest® (nor...

journal_title：Neuroendocrinology

authors： van Treijen MJC,van der Zee D,Heeres BC,Staal FCR,Vriens MR,Saveur LJ,Verbeek WHM,Korse CM,Maas M,Valk GD,Tesselaar M

更新日期：2020-06-03 00:00:00

abstract：:Administration of the bovine pineal peptide threonylseryllysine (TSL) to unilaterally ovariectomized (UO) mice as a single intraperitoneal injection on the day of UO reduced the 5-day compensatory ovarian hypertrophy. The same dose of TSL (175 ng/animal) significantly (p less than 0.01) reduced serum follicle stimulat...

journal_title：Neuroendocrinology

authors： Orts RJ,Bruot BC,Sartin JL

更新日期：1980-08-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:Our previous studies on annexin 5, a member of the annexin family of proteins, have shown its expression in the anterior pituitary gland, its preferential distribution in gonadotropes, and its increase after ovariectomy. In the present study, we examined (1) whether annexin 5 is synthesized in gonadotropes, (2) whethe...

journal_title：Neuroendocrinology

authors： Kawaminami M,Etoh S,Miyaoka H,Sakai M,Nishida M,Kurusu S,Hashimoto I

更新日期：2002-01-01 00:00:00

abstract：:Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...

journal_title：Neuroendocrinology

authors： Simar MR,Saphier D,Goeders NE

更新日期：1996-01-01 00:00:00

abstract：:In vitro and in vivo perfusion techniques were used to examine the changes in the release of beta-endorphin, methionine-enkephalin (met-enkephalin), dynorphin and luteinizing hormone releasing hormone (LHRH) in response to the corticotropin releasing factor (CRF) receptor antagonist, alpha-helical CRF9-41. All four pe...

journal_title：Neuroendocrinology

authors： Nikolarakis KE,Almeida OF,Sirinathsinghji DJ,Herz A

更新日期：1988-06-01 00:00:00

abstract：:We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3-4 days. The present study was undertaken to determine the time after castration when ...

journal_title：Neuroendocrinology

authors： Kalra PS

更新日期：1985-09-01 00:00:00

abstract：:The properties of neuronal-type nicotinic acetylcholine receptors (nAChRs) present on the neuroendocrine cells of the porcine pars intermedia of the pituitary were studied in intact single cell using measurements of the free intracellular Ca2+ concentration ([Ca]i) with the calcium-sensitive dye fura 2. Local applicat...

journal_title：Neuroendocrinology

authors： Poisbeau P,Trouslard J,Feltz P,Schlichter R

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND/AIMS:The medial amygdala (MeA) responds to olfactory stimuli and alters reproductive physiology. However, the neuronal circuit that relays signals from the MeA to the reproductive axis remains poorly defined. This study aimed to test whether MeA kisspeptin (MeAKiss) neurons in male mice are sensitive to sexu...

journal_title：Neuroendocrinology

authors： Aggarwal S,Tang C,Sing K,Kim HW,Millar RP,Tello JA

更新日期：2019-01-01 00:00:00

abstract：:The sleep-wakefulness pattern and brain protein levels were determined in rats for 3 h following these conditions: administration of an inhibitor of protein synthesis (anisomycin), administration of several doses of rat growth hormone (GH) or thyrotropin, and administration of a combination of anisomycin + GH or thyro...

journal_title：Neuroendocrinology

authors： Drucker-Colín RR,Spanis CW,Hunyadi J,Sassin JF,McGaugh JL

更新日期：1975-01-01 00:00:00

abstract：:The pituitary-adrenal axis is known to be stimulated during the acute-phase response. As cytokines play a central role in mediating the constellation of host response occurring during the acute-phase response it was of interest to assess the ability of cytokines to stimulate ACTH secretion from normal pituitary cells ...

journal_title：Neuroendocrinology

authors： Kehrer P,Turnill D,Dayer JM,Muller AF,Gaillard RC

更新日期：1988-08-01 00:00:00

abstract：:An experiment was performed on 21-day-old male rats to determine the combined effects of pinealectomy, constant light and darkness, and intraperitoneal (i.p.) thyrotropin-releasing hormone (TRH) on pituitary and plasma radioimmunoassayable thyrotropin (TSH), serum thyroxine (T4), and pituitary, thyroid and body weight...

journal_title：Neuroendocrinology

authors： Relkin R

更新日期：1978-01-01 00:00:00

abstract：:The effects of acute stress exposure upon cholecystokinin (CCK) and substance P (SP) concentrations in discrete hypothalamic regions of the adult male rat brain were studied. Animals were exposed to foot shock stress for periods of 2, 4, 10, 30 or 60 min duration; immediately afterwards they were decapitated; brains w...

journal_title：Neuroendocrinology

authors： Siegel RA,Düker EM,Pahnke U,Wuttke W

更新日期：1987-06-01 00:00:00

abstract：:The growth hormone secretagogue receptor subtype 1a (GHSR-1a) is involved in biological actions of ghrelin by triggering intracellular second messengers coupled to heterotrimeric G-protein complex involving Galpha(q/11). Adenosine is a partial agonist of the GHSR-1a, binding to a binding pocket distinct from the one d...

journal_title：Neuroendocrinology

authors： Carreira MC,Camiña JP,Smith RG,Casanueva FF

更新日期：2004-01-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:The clinicopathological features of lung neuroendocrine neoplasms (NEN) with a high proliferative index at the border area between atypical carcinoid and neuroendocrine carcinoma have not been investigated so far. The aim of this study was, therefore, to search for lung NENs which are well differentiated but show Ki67...

journal_title：Neuroendocrinology

authors： Kasajima A,Konukiewitz B,Oka N,Suzuki H,Sakurada A,Okada Y,Kameya T,Ishikawa Y,Sasano H,Weichert W,Klöppel G

更新日期：2019-01-01 00:00:00

abstract：:Nontropical rodents have evolved adaptations to maximize winter survival, including alterations in reproduction, energy balance and immunity. Short-day-housed Siberian hamsters display reductions in body fat and decreases in humoral immunity compared with long-day hamsters. The hormone leptin, secreted by adipose tiss...

journal_title：Neuroendocrinology

authors： Demas GE

更新日期：2002-09-01 00:00:00

abstract：:The exact physiological basis of acute growth hormone (GH) suppression by oral glucose is not fully understood. Glucose-mediated increase in hypothalamic somatostatin seems to be the most plausible explanation. Attempts to better understand its underlying mechanisms are compromised by species disparities in the respon...

journal_title：Neuroendocrinology

authors： Hage M,Kamenický P,Chanson P

更新日期：2019-01-01 00:00:00