Effect of steroids on vasoactive intestinal peptide in discrete brain regions and peripheral tissues.

Abstract:

:The effect of castration and adrenalectomy was studied on vasoactive intestinal peptide (VIP) concentrations in various brain and peripheral structures of male rats. Castration has no effect on any of the structures studied, whereas 4 weeks adrenalectomy (ADX) decreases VIP concentrations in the hippocampus and increases them in the adenohypophysis, two structures known to contain large amounts of glucocorticoid receptors. Corticosterone administration restores VIP levels to control values only in the dorsal hippocampus. In contrast, dexamethasone counteracts both the decrease and the increase of VIP concentrations obtained after ADX in the hippocampus and in the adenohypophysis respectively. The present results suggest that corticosteroids can be involved in the regulation of VIP actions both in the brain and in the adenohypophysis.

journal_name

Neuroendocrinology

journal_title

Neuroendocrinology

authors

Rotsztejn WH,Besson J,Briaud B,Gagnant L,Rosselin G,Kordon C

doi

10.1159/000123090

subject

Has Abstract

pub_date

1980-10-01 00:00:00

pages

287-91

issue

4

eissn

0028-3835

issn

1423-0194

journal_volume

31

pub_type

杂志文章
  • Opioid receptor subtype involvement in maternal behavior in lactating rats.

    abstract::Central or systemic administration of morphine disrupts maternal behavior in steroid-primed, pup-induced virgin and lactating rats. Morphine, the prototypical mu agonist, also interacts with different opioid receptor subtypes. The present study examined the effectiveness of five receptor-selective agonists, in additio...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125762

    authors: Mann PE,Kinsley CH,Bridges RS

    更新日期:1991-05-01 00:00:00

  • The endogenous stimulatory rhythm regulating prolactin secretion is present in the lactating rat.

    abstract::Prolactin (PRL) secretion in the female rat is regulated by an endogenous stimulatory rhythm (ESR), which is normally under the tonic inhibition of dopamine (DA). The ESR consists of a nocturnal (N) component which peaks at approximately 03.00 h, and a diurnal (D) component which peaks at approximately 17.00 h. This E...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125694

    authors: Arey BJ,Kanyicska B,Freeman ME

    更新日期:1991-01-01 00:00:00

  • Purification and characterization of urotensin II and parvalbumin from an elasmobranch fish, Scyliorhinus canicula (common dogfish).

    abstract::The caudal portion of the spinal cord of elasmobranch fish incorporates a diffuse neuroendocrine system. Using an antiserum raised against urotensin II from a teleost fish (goby) to facilitate purification, a peptide structurally related to urotensin II was isolated in pure form from an extract of neuroendocrine tissu...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126119

    authors: Conlon JM,O'Harte F,Smith DD,Balment RJ,Hazon N

    更新日期:1992-02-01 00:00:00

  • Effects of estrogen on oxytocin receptor messenger ribonucleic acid expression in the uterus, pituitary, and forebrain of the female rat.

    abstract::Oxytocin receptors are regulated during parturition and lactation. Gonadal steroids are thought to be key players in this regulation. It is not well documented how oxytocin receptor gene expression is regulated in the CNS. In this study we analyzed potential estrogen effects on the oxytocin receptor mRNA levels in som...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000127160

    authors: Quiñones-Jenab V,Jenab S,Ogawa S,Adan RA,Burbach JP,Pfaff DW

    更新日期:1997-01-01 00:00:00

  • Thyroid hormone level positively regulates NOS and cGMP in the developing rat cerebellum.

    abstract::Thyroid hormones and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling play a significant role in the structural development of the cerebellum, respectively. In the present study, the possible contribution of neuronal NO synthase (NOS) and cGMP in the thyroid hormone-induced structural changes was invest...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000203644

    authors: Serfozo Z,de Vente J,Elekes K

    更新日期:2009-01-01 00:00:00

  • Stimulation of the Hypothalamus and FSH and LH secretion in the ferret.

    abstract::The acute effects of hypothalamic electrical stimulation on the secretion of FSH and LH have been examined in anestrous and estrous ferrets. Basal levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were higher in the anestrous than in the estrous animals; the anestrous animals showed a more mark...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000122674

    authors: Donovan BT,ter Haar MB

    更新日期:1977-01-01 00:00:00

  • Experimentally induced hyperthyroidism disrupts hippocampal long-term potentiation in adult rats.

    abstract:BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000328513

    authors: Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

    更新日期:2011-01-01 00:00:00

  • Effects of short-term constant light on the proestrous luteinizing hormone surge and pituitary responsiveness in the female rat.

    abstract::We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123225

    authors: Watts AG,Fink G

    更新日期:1981-09-01 00:00:00

  • Muscarinic receptors in the preoptic area are sensitive to 17 beta-estradiol during the critical period.

    abstract::The relationship between the steroid hormone 17 beta-estradiol and the muscarinic cholinergic receptors present in the preoptic area (POA), median hypothalamus and posterior hypothalamus of female rats was examined in vitro at various stages of the estrous cycle. Muscarinic receptors varied in a cyclic manner, specifi...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000124103

    authors: Egozi Y,Kloog Y

    更新日期:1985-05-01 00:00:00

  • Regulation of prolactin secretion by dopamine at the level of the hypothalamus in the turkey.

    abstract::Avian prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) neurons residing in the infundibular nuclear complex (INF) of the hypothalamus. This VIPergic activity is modulated by stimulatory dopaminergic inputs. Dynorphin, serotonin (5-HT), dopamine (DA) and VIP all appear to stimulate PRL secr...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000048236

    authors: Youngren O,Chaiseha Y,Al-Zailaie K,Whiting S,Kang SW,El Halawani M

    更新日期:2002-03-01 00:00:00

  • Sheep pineal beta-adrenoceptor function--interaction with gamma-aminobutyric acid.

    abstract::To clarify the role and site of action of gamma-aminobutyric acid (GABA) in ovine pineal glands, we have investigated the effects of aminooxyacetic acid (AOAA), an inhibitor of GABA transaminase, on endogenous GABA content and beta-adrenoceptor mediated pineal function in Merino sheep. A significant elevation of endog...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123892

    authors: Foldes A,Maxwell CA,Rintoul AJ,Edols RW

    更新日期:1984-03-01 00:00:00

  • Luteinising hormone secretion from the perifused ovine pars tuberalis and pars distalis: effects of gonadotropin-releasing hormone and melatonin.

    abstract::It is not known where melatonin acts to influence the neuroendocrine axis of seasonally breeding mammals. However, since the pars tuberalis (PT) contains the highest density of melatonin receptors, this adenohypophyseal subdivision is a potential target. Gonadotropes are the only immunocytochemically detectable adenoh...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000127247

    authors: Skinner DC,Robinson JE

    更新日期:1997-10-01 00:00:00

  • Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage caused by middle cerebral artery occlusion in the ovariectomized female rat.

    abstract::Previous work has demonstrated that physiological concentrations of 17beta-estradiol can protect the female rat brain against middle cerebral artery occlusion (MCAO)-induced ischemic damage. The present study examined whether therapeutic doses of the clinically relevant selective estrogen receptor modulator (SERM), ta...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000068332

    authors: Mehta SH,Dhandapani KM,De Sevilla LM,Webb RC,Mahesh VB,Brann DW

    更新日期:2003-01-01 00:00:00

  • Prolactin expression in the sheep brain.

    abstract::Accumulating evidence in rodents suggests that a prolactin locally synthesized and released within the brain can act together with that taken up from the circulation to modulate neuroendocrine responses. The present study was designed to identify the regional patterns of prolactin expression in the adult and developin...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000114643

    authors: Roselli CE,Bocklandt S,Stadelman HL,Wadsworth T,Vilain E,Stormshak F

    更新日期:2008-01-01 00:00:00

  • Stimulation of prolactin secretion by neuroleptics in rats with medial basal hypothalamic lesions.

    abstract::The ability of dopamine receptor antagonists to stimulate prolactin release in rats with medial basal hypothalamic lesions was investigated. Starting levels of prolactin were elevated to approximately 400 ng/ml in animals in which the tuberoinfundibular dopaminergic neurons were completely destroyed by the lesion. In ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123188

    authors: Cheung CY,Neill AC,Weiner RI

    更新日期:1981-06-01 00:00:00

  • Progesterone reverses the estradiol-induced decrease in tyrosine hydroxylase mRNA levels in the arcuate nucleus.

    abstract::Estradiol (E2) and progesterone (P4) interact to influence tuberoinfundibular dopaminergic neuronal activity and contribute to the control of prolactin (PRL) release. This study examined tyrosine hydroxylase mRNA signal levels in the arcuate nucleus of the hypothalamus and tyrosine hydroxylase activity in the stalk-me...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126583

    authors: Arbogast LA,Voogt JL

    更新日期:1993-11-01 00:00:00

  • Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and Progression.

    abstract:AIM:To extensively explore microRNA expression profiles in lung carcinoids in correlation with clinical and pathological features. METHODS:A PCR-based array was employed in the screening phase to analyze 752 microRNAs in a discovery set of 12 lung carcinoids, including 6 typical (3 with lymph node metastasis) and 6 at...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000381454

    authors: Rapa I,Votta A,Felice B,Righi L,Giorcelli J,Scarpa A,Speel EJ,Scagliotti GV,Papotti M,Volante M

    更新日期:2015-01-01 00:00:00

  • Stress symptoms induced by repeated morphine withdrawal in comparison to other chronic stress models in mice.

    abstract::The present study was aimed at evaluating chronic stress models in mice with special attention to morphine treatment. We hypothesized that repeated periods of drug withdrawal induce chronic stress. To verify this hypothesis, mice were made dependent on morphine and then subjected to several types of repeated withdrawa...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000087034

    authors: Zelena D,Barna I,Mlynarik M,Gupta OP,Jezova D,Makara GB

    更新日期:2005-01-01 00:00:00

  • Salt appetite in salt-replete rats: involvement of mesolimbic structures in deoxycorticosterone-induced salt craving behavior.

    abstract::Chronic administration of the mineralocorticoid deoxycorticosterone acetate (DOCA) induces a steady and robust increase in salt appetite and plasma Na(+) over the course of treatment. Interestingly, salt appetite behavior persists in rats even with elevated plasma Na(+) levels. Since there is evidence that the pathway...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000054559

    authors: Lucas LR,Pompei P,McEwen BS

    更新日期:2000-06-01 00:00:00

  • 17-beta-estradiol potentiates luteinizing hormone glycosylation and release induced by veratridine, diacylglycerol, and phospholipase C in rat anterior pituitary cells.

    abstract::We determined the effect of 17 beta-estradiol (E2) on synthesis and release of luteinizing hormone (LH) induced by drugs which activate intracellular signal transduction mechanisms in rat anterior pituitary cells. Cells were pretreated with E2 (6 x 10(-10) M) or diluent for 24 h, then washed and incubated for 4 h with...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125405

    authors: Liu TC,Jackson GL

    更新日期:1990-06-01 00:00:00

  • Effects of tumor-induced hyperprolactinemia on LH secretion following stimulation of the medial preoptic area, pituitary responsiveness and the estrogen-induced LH surge.

    abstract::In the present study we utilized the 7315a PRL- and ACTH-secreting tumor to induce a hyperprolactinemic (HP) state sufficient to profoundly suppress the postcastration LH rise in female rats. Tumor-induced prolactin levels which ranged 2,000-3,000 ng/ml substantially reduced the LH rise in both ovariectomized (OVX) an...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125880

    authors: Shu C,Selmanoff M

    更新日期:1991-09-01 00:00:00

  • Loperamide inhibits corticotrophic cell function by a naloxone-insensitive mechanism in the rat in vitro.

    abstract::The effect of the antidiarrheal drug loperamide, a mu-opiate agonist, on ACTH secretion and biosynthesis, cAMP generation and phosphoinositide turnover was studied in rat anterior pituitary cell cultures. The cAMP-dependent protein kinase A pathway was stimulated with both corticotropin-releasing hormone (CRH; 2-5 nM)...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126466

    authors: Auernhammer CJ,Renner U,Müller OA,Stalla J,Stalla GK

    更新日期:1993-06-01 00:00:00

  • Gaseous transmitters and neuroendocrine regulation.

    abstract::Recent work has demonstrated that the brain has the capacity to synthesize impressive amounts of the gases nitric oxide (NO) and carbon monoxide (CO). There is growing evidence that these gaseous molecules function as novel neural messengers in the brain. This article reviews the pertinent literature concerning the pu...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,评审

    doi:10.1159/000127201

    authors: Brann DW,Bhat GK,Lamar CA,Mahesh VB

    更新日期:1997-06-01 00:00:00

  • Corticosteroids influence the action potential firing pattern of hippocampal subfield CA3 pyramidal cells.

    abstract::Corticosteroids regulate gene expression through the activation of mineralocorticoid and glucocorticoid receptors. The hippocampus contains the highest density of mineralocorticoid and glucocorticoid receptors in the central nervous system. The modulation of neuron excitability by corticosteroids in hippocampal subfie...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000054299

    authors: Okuhara DY,Beck SG

    更新日期:1998-01-01 00:00:00

  • 68Gallium DOTANOC-PET Imaging in Lung Carcinoids: Impact on Patients' Management.

    abstract:BACKGROUND:68Gallium DOTA-PET imaging is preferable to standard somatostatin receptor scintigraphy where available; however, its role in the management of lung carcinoid tumours (LC) remains unclear. METHODS:All consecutive patients with histologically confirmed LC from two ENETS Centres of Excellence were identified ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000472717

    authors: Lamarca A,Pritchard DM,Westwood T,Papaxoinis G,Nonaka D,Vinjamuri S,Valle JW,Manoharan P,Mansoor W

    更新日期:2018-01-01 00:00:00

  • Comparative immunohistochemical study of the distribution of neuropeptide Y, growth hormone-releasing factor and the carboxyterminus of precursor protein GHRF in the human hypothalamic infundibular area.

    abstract::It is now well documented that various polyclonal antisera to the human growth hormone-releasing factor (hGHRF, somatocrinin) visualize in the brain by immunohistochemistry the classical hypothalamic hypophysiotropic neurons and also antigens present in otherwise characterized peptidergic neuronal systems. The nature ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125370

    authors: Ciofi P,Tramu G,Bloch B

    更新日期:1990-04-01 00:00:00

  • Opposite changes of pituitary and ovarian receptors for LHRH in ageing rats: further evidence for a direct neural control of ovarian LHRH receptor activity.

    abstract::Hypophyseal and ovarian receptors for the neurohormone LHRH (LHRH-R) have been measured in young (3-4 months), middle-aged (8-11 months), constant estrous (CE, 10-14 months) and pseudopregnant (PR, 16-18 months) rats in order to study whether changes in hypothalamic and/or peripheral LHRH-like peptide production might...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125018

    authors: Marchetti B,Cioni M

    更新日期:1988-09-01 00:00:00

  • Growth hormone-releasing hormone: clinical studies and therapeutic aspects.

    abstract::Growth hormone-releasing hormone (GHRH) stimulates GH secretion in man and the hormonal response is specific. The attenuation of GH response to bolus GHRH after prior exposure of GHRH of up to 24 h was not demonstrated in normal or GH-deficient subjects after more prolonged exposure. This suggests that the partial los...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,评审

    doi:10.1159/000125793

    authors: Low LC

    更新日期:1991-01-01 00:00:00

  • Central electrophysiologic correlates of pulsatile luteinizing hormone secretion in the rhesus monkey.

    abstract::Characteristic increases in neuronal activity coincident with the pulsatile release of luteinizing hormone from the pituitary gland have been recorded from electrodes chronically implanted in the medial basal hypothalamus of the rhesus monkey. This electrophysiologic manifestation of the hypothalamic 'pulse generator'...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123988

    authors: Wilson RC,Kesner JS,Kaufman JM,Uemura T,Akema T,Knobil E

    更新日期:1984-09-01 00:00:00

  • Site of gamma-aminobutyric acid (GABA)-mediated inhibition of growth hormone secretion in the rat.

    abstract::The effect of altering gamma-aminobutyric acid (GABA) activity on growth hormone (GH) secretion of freely moving chronically cannulated male rats was studied. Systemic injection of the GABA agonist muscimol (2 mg/kg i.v.) inhibited the anticipated secretory episode. Increasing brain GABA levels by gamma-acetylenic-GAB...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000124031

    authors: Fiók J,Acs Z,Makara GB,Erdö SL

    更新日期:1984-12-01 00:00:00