Use of melatonin and synthetic TRH to determine site of pineal inhibition of TSH secretion.

abstract：:Measurements of electrical activity and intracellular Ca(2+) levels were performed in perforated-patch clamped GH(3) cells to determine the contribution of large-conductance calcium-activated K(+) (BK) channels to action potential repolarization and size of the associated Ca(2+) oscillations. By examining the dependen...

journal_title：Neuroendocrinology

authors： Miranda P,de la Peña P,Gómez-Varela D,Barros F

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Activation of somatostatin receptors (sstr1-5) by somatostatin and its analogues exerts an inhibitory effect on hormone secretion and provides the basis for the treatment of a range of endocrine diseases such as acromegaly, Cushing's disease and neuroendocrine tumors (NET). The lack of well-characterized com...

journal_title：Neuroendocrinology

authors： Schmid HA,Lambertini C,van Vugt HH,Barzaghi-Rinaudo P,Schäfer J,Hillenbrand R,Sailer AW,Kaufmann M,Nuciforo P

更新日期：2012-01-01 00:00:00

abstract：:Previous studies have shown that the hypothalamic concentration of pro-opiomelanocortin (POMC) mRNA and several POMC-derived peptides increases in the rat 4 weeks after orchiectomy and that this increase can be prevented by testosterone replacement. In this study, we have examined the short-term effects of orchiectomy...

journal_title：Neuroendocrinology

authors： Wardlaw SL,Blum M

更新日期：1990-11-01 00:00:00

abstract：:We have investigated the hypothesis that administration of progesterone to estrogen-treated ovariectomized (OVX) rats enhances the stimulatory effects of neuropeptide Y (NPY) on the secretion of luteinizing hormone-releasing hormone (LHRH) from median eminence (ME) fragments in vitro. Adult rats were bilaterally OVX a...

journal_title：Neuroendocrinology

authors： Sabatino FD,Collins P,McDonald JK

更新日期：1990-12-01 00:00:00

abstract：:Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

journal_title：Neuroendocrinology

authors： Lytras A,Tolis G

更新日期：2006-01-01 00:00:00

abstract：:The presence of vasopressin (VP) in pars distalis of rats and pigs was investigated. Using radioimmunoassay and bioassay of VP, a substance with immunological and biological properties of this hormone was found. This substance was not detected in the adenohypophysis of rats with diabetes insipidus. A partial purificat...

journal_title：Neuroendocrinology

authors： Chateau M,Marchetti J,Burlet A,Boulange M

更新日期：1979-01-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP), a prolactin (PRL)-releasing factor, has been shown to be synthesized within the anterior pituitary. To test the hypothesis that estrogens increase PRL secretion, at least in part, by stimulating VIP secretion, the concentrations of VIP, peptide histidine isoleucine (PHI) and prepro...

journal_title：Neuroendocrinology

authors： Lam KS,Srivastava G,Lechan RM,Lee T,Reichlin S

更新日期：1990-11-01 00:00:00

abstract：:Previous studies have indicated that 30 min of swimming in room temperature water is a potent stimulus for the secretion of beta-endorphin (beta E) from the intermediate lobe (IL) of the pituitary in rodents. Repeated daily challenge with this paradigm over days to weeks leads to a progressive increase in proopiomelan...

journal_title：Neuroendocrinology

authors： Young EA,Bronstein D,Akil H

更新日期：1993-09-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with reproductive, metabolic, and psychological features and significantly increased cardiometabolic risks. PCOS is underpinned by inherent insulin resistance and hyperandrogenism. Obesity, more common in PCOS, plays an important role in the patho...

journal_title：Neuroendocrinology

authors： Chiu WL,Boyle J,Vincent A,Teede H,Moran LJ

更新日期：2017-01-01 00:00:00

abstract：:The effect of intravertebral infusion of angiotensin II on cardiac vagal efferent activity was studied in anesthetized mongrel dogs. Unilateral infusion of doses of angiotensin II as low as 5 ng/kg/min inhibited basal vagal tone and also decreased the slope of the relationship between cardiac vagal efferent activity a...

journal_title：Neuroendocrinology

authors： Potter EK,Reid IA

更新日期：1985-06-01 00:00:00

abstract：:The effects of melatonin administration on thyroid physiology of female hamsters was investigated. A protocol of 25 micrograms given daily as subcutaneous injections late in the light period was found to inhibit blood levels of thyroxin (T4), triiodothyronine (T3) and thyrotropin (TSH). The free T4 index (FT4I) and th...

journal_title：Neuroendocrinology

authors： Vriend J,Richardson BA,Vaughan MK,Johnson LY,Reiter RJ

更新日期：1982-01-01 00:00:00

abstract：:The effects of the dopamine (DA) receptor antagonist metoclopramide on the plasma thyroid stimulating hormone (TSH) and prolactin (PRL) levels were studied in 8 patients with subclinical hypothyroidism (defined as absence of clinical signs of hypothyroidism with normal thyroid hormone levels, normal or slightly increa...

journal_title：Neuroendocrinology

authors： Lombardi G,Iodice M,Miletto P,Merola B,Panza N,Annunziato L

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:68Gallium DOTA-PET imaging is preferable to standard somatostatin receptor scintigraphy where available; however, its role in the management of lung carcinoid tumours (LC) remains unclear. METHODS:All consecutive patients with histologically confirmed LC from two ENETS Centres of Excellence were identified ...

journal_title：Neuroendocrinology

authors： Lamarca A,Pritchard DM,Westwood T,Papaxoinis G,Nonaka D,Vinjamuri S,Valle JW,Manoharan P,Mansoor W

更新日期：2018-01-01 00:00:00

abstract：:The effect of aging on the release of gonadotropin-releasing hormone (GnRH) in vitro and of luteinizing hormone (LH) both in vivo and in vitro in ovariectomized (Ovx) rats was studied. Old (21-24 months) and young (3-4 months) rats were Ovx before use. They were injected subcutaneously with estradiol benzoate (25 micr...

journal_title：Neuroendocrinology

authors： Hwang C,Pu HF,Hwang CY,Liu JY,Yao HC,Tung YF,Wang PS

更新日期：1990-08-01 00:00:00

abstract：:The arcuate nucleus-median eminence complex (AM) undergoes major structural and functional changes during normal puberty or if exposed to a pulse of estradiol in the prepuberal period. Those changes are expressed by increased synaptogenesis and by a drastic alteration in the feedback control of anterior pituitary glan...

journal_title：Neuroendocrinology

authors： Rodriguez-Sierra JF,Heydorn WE,Creed GJ,Jacobowitz DM

更新日期：1987-06-01 00:00:00

abstract：:The differences in plasma prolactin concentration between normal and estradiol-implanted male rats were compared after treatment with 3 different stimulating agents of prolactin secretion [ether anesthesia, pimozide (a "specific' dopaminergic receptor blocking agent) and TRH] using conscious, free-moving rats implante...

journal_title：Neuroendocrinology

authors： Piercy M,Shin SH

更新日期：1980-10-01 00:00:00

abstract：:The hypothalamic preoptic area (POA) was electrically stimulated through permanently implanted electrodes in 4 unanesthetized sheep. Initiation of POA stimulation was followed witin 10-20 min by large increases in plasma levels of prolactin (PRL). The stimulation-induced discharges of PRL were consistently observed in...

journal_title：Neuroendocrinology

authors： Malven PV

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

journal_title：Neuroendocrinology

authors： Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

更新日期：2011-01-01 00:00:00

abstract：:Histamine (HA) stimulates the release of the pro-opiomelanocortin (POMC)-derived peptides ACTH, beta-endorphin (beta-END), beta-lipotropin and alpha-melanocyte-stimulating hormone, and HA is involved in the mediation of the stress-induced release of these peptides. The effect of HA is indirect and may involve the hypo...

journal_title：Neuroendocrinology

authors： Kjaer A,Knigge U,Bach FW,Warberg J

更新日期：1992-09-01 00:00:00

abstract：INTRODUCTION:The pituitary gland has a high expression of somatostatin receptors (SSTRs) and is therefore a potential organ at risk for radiation-induced toxicity after 177Lu-DOTATATE treatment. OBJECTIVE:To study changes in pituitary function in patients with neuroendocrine tumors (NETs) treated with dosimetry-based ...

journal_title：Neuroendocrinology

authors： Sundlöv A,Sjögreen-Gleisner K,Tennvall J,Dahl L,Svensson J,Åkesson A,Bernhardt P,Lindgren O

更新日期：2020-04-08 00:00:00

abstract：:Medial parvocellular paraventricular corticotropin-releasing hormone (mPVN CRH) cells are critical in generating hypothalamic-pituitary-adrenal (HPA) axis responses to systemic interleukin-1beta (IL-1beta). However, although it is understood that catecholamine inputs are important in initiating mPVN CRH cell responses...

journal_title：Neuroendocrinology

authors： Buller K,Xu Y,Dayas C,Day T

更新日期：2001-02-01 00:00:00

abstract：:The present study was designed to investigate whether the vasoactive intestinal peptide (VIP) concentration in hypothalamic nuclei, dorsal raphe nucleus (DR) and pituitary lobes of lactating rats changes in physiological situations when prolactin (PRL) secretion is stimulated (suckling) or inhibited (pup separation). ...

journal_title：Neuroendocrinology

authors： Chiocchio SR,de las Nieves Parisi M,Vitale ML,Tramezzani JH

更新日期：1991-07-01 00:00:00

abstract：:Several molecular forms related to the decapeptide LHRH were characterized and quantified in various brain structures of intact and castrated male and female rats. Distinct moieties were separated by high performance liquid chromatography (HPLC) and radioimmunoassayed against anti-LHRH antibodies of different specific...

journal_title：Neuroendocrinology

authors： Gautron JP,Pattou E,Leblanc P,L'Héritier A,Kordon C

更新日期：1993-08-01 00:00:00

abstract：:An initial study was performed to ascertain the effects of anisomycin, a reversible inhibitor of protein synthesis, on pulsatile luteinizing hormone (LH) release in adult, ovarietomized (OVX) rats. For this experiment, rats OVX 3-4 weeks earlier were fitted with indwelling atrial cannulae. On the next day (approximate...

journal_title：Neuroendocrinology

authors： DePaolo LV

更新日期：1989-07-01 00:00:00

abstract：:We studied the effect that beta-endorphin (beta END) might have at the median eminence (ME) on luteinizing hormone (LH)-releasing hormone (LHRH) during the ovulatory cycle of domestic hens. Thus, we assessed (a) the immunocytochemical distribution of beta END and LHRH in the hen ME, (b) the temporal changes in ME and ...

journal_title：Neuroendocrinology

authors： Contijoch AM,Malamed S,Sarkar DK,Advis JP

更新日期：1993-01-01 00:00:00

abstract：:Secretion of the growth hormone (GH) in spontaneously hypertensive (SH) male rats has been determined and compared with that of normotensive Wistar-Kyoto (WKY) controls. In a first set of experiments, plasma GH concentration and pituitary GH content were measured in SH rats 30, 60 and 90 days old. 30-day rats showed r...

journal_title：Neuroendocrinology

authors： Aguilar E,Rodríguez ML,Bellido C,de la Fuente M,Pinilla L

更新日期：1990-10-01 00:00:00

abstract：:The recent description of infertility in humans with loss-of-function mutations in genes for neurokinin B (NKB) or its receptor (NK3R) has focused attention on the importance of this tachykinin in the control of GnRH secretion. In a number of species, NKB neurons in the arcuate nucleus also produce two other neuropept...

journal_title：Neuroendocrinology

authors： Goodman RL,Coolen LM,Lehman MN

更新日期：2014-01-01 00:00:00

abstract：:[125I]-neuropeptide Y receptors were characterized in the rat pituitary gland using quantitative autoradiography. Scatchard analysis of saturation isotherms showed high affinity (Kd 8.5 x 10(-11) M) and single class of binding sites (Bmax 0.22 pmol/mg of protein) in the posterior lobe of the pituitary gland, with no s...

journal_title：Neuroendocrinology

authors： Torda T,Saavedra JM

更新日期：1990-10-01 00:00:00

abstract：:The relationship between the steroid hormone 17 beta-estradiol and the muscarinic cholinergic receptors present in the preoptic area (POA), median hypothalamus and posterior hypothalamus of female rats was examined in vitro at various stages of the estrous cycle. Muscarinic receptors varied in a cyclic manner, specifi...

journal_title：Neuroendocrinology

authors： Egozi Y,Kloog Y

更新日期：1985-05-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) stimulates GH secretion in man and the hormonal response is specific. The attenuation of GH response to bolus GHRH after prior exposure of GHRH of up to 24 h was not demonstrated in normal or GH-deficient subjects after more prolonged exposure. This suggests that the partial los...

journal_title：Neuroendocrinology

authors： Low LC

更新日期：1991-01-01 00:00:00