Beta-endorphin regulation of LHRH release at the median eminence level: immunocytochemical and physiological evidence in hens.

abstract：:The effect of frontal deafferentation of the medial basal hypothalamus on pro-opiomelanocortin (POMC) gene expression was studied in the intermediate lobe (IL) and anterior lobe (AL) of the pituitary gland in the absence and presence of corticosterone (CORT). The lesion in the basal hypothalamus removed neural inputs ...

journal_title：Neuroendocrinology

authors： Seger MA,van Eekelen JA,Kiss JZ,Burbach JP,de Kloet ER

更新日期：1988-04-01 00:00:00

abstract：:Previous studies indicate that 7 days after testicular administration of naloxone, serum testosterone (T) concentration and basal T secretion in vitro decrease significantly. In neonatal rats, short-term (2 h) intratesticular treatment with 0.3 micrograms (D-Met2-Pro5)-enkephalinamide suppresses steroidogenesis. In th...

journal_title：Neuroendocrinology

authors： Gerendai I,Nemeskéri A,Csernus V

更新日期：1992-09-01 00:00:00

abstract：:Bromocriptine or other dopamine agonists are usually effective for the treatment of prolactin-secreting adenomas. Five to 18% of prolactinomas, however, do not respond to such therapy. We have shown previously that such resistance to bromocriptine correlates with reduced binding to the D2 receptor subtype of dopamine,...

journal_title：Neuroendocrinology

authors： Caccavelli L,Feron F,Morange I,Rouer E,Benarous R,Dewailly D,Jaquet P,Kordon C,Enjalbert A

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The appetite-stimulating hormone ghrelin is a fundamental regulator of human energy metabolism. A series of studies support the notion that long-term appetite and weight regulation may be already programmed in early life and it could be demonstrated that the intrauterine environment affects the ghrelin syste...

journal_title：Neuroendocrinology

authors： Paslakis G,Buchmann AF,Westphal S,Banaschewski T,Hohm E,Zimmermann US,Laucht M,Deuschle M

更新日期：2014-01-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with reproductive, metabolic, and psychological features and significantly increased cardiometabolic risks. PCOS is underpinned by inherent insulin resistance and hyperandrogenism. Obesity, more common in PCOS, plays an important role in the patho...

journal_title：Neuroendocrinology

authors： Chiu WL,Boyle J,Vincent A,Teede H,Moran LJ

更新日期：2017-01-01 00:00:00

abstract：:In the present study we demonstrated that TLQP-21, a biologically active peptide derived from the processing of the larger pro-VGF granin, plays a role in mammotrophic cell differentiation. We used an established in vitro model, the GH3 cell line, which upon treatment with epidermal growth factor develops a mammotroph...

journal_title：Neuroendocrinology

authors： Petrocchi Passeri P,Biondini L,Mongiardi MP,Mordini N,Quaresima S,Frank C,Baratta M,Bartolomucci A,Levi A,Severini C,Possenti R

更新日期：2013-01-01 00:00:00

abstract：:To study the role of the hypothalamus in the regulation of growth hormone (GH) synthesis, the rate of amino acid incorporation into GH in vitro was examined in rats with anterolateral deafferentation of the medial basal hypothalamus. Amino acid incorporation into GH (GH synthesis) decreased significantly 7 days after ...

journal_title：Neuroendocrinology

authors： Ieiri T,Ishikawa K,Suzuki M,Shimoda S

更新日期：1988-05-01 00:00:00

abstract：:Histamine (HA) stimulates the release of the pro-opiomelanocortin (POMC)-derived peptides ACTH, beta-endorphin (beta-END), beta-lipotropin and alpha-melanocyte-stimulating hormone, and HA is involved in the mediation of the stress-induced release of these peptides. The effect of HA is indirect and may involve the hypo...

journal_title：Neuroendocrinology

authors： Kjaer A,Knigge U,Bach FW,Warberg J

更新日期：1992-09-01 00:00:00

abstract：:Hyponatremia due to elevated arginine vasopressin (AVP) secretion increases mortality in liver failure patients. The mechanisms causing dysregulation of AVP secretion are unknown. Our hypothesis is that inappropriate AVP release associated with liver failure is due to increased brain-derived neurotrophic factor (BDNF)...

journal_title：Neuroendocrinology

authors： Balapattabi K,Little JT,Bachelor M,Cunningham JT

更新日期：2020-01-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:Neuronal nitric oxide synthase, e.g. NADPH diaphorase (NADPH-d), catalyzes formation of the free radical, nitric oxide (NO), and occurs within brain structures that have functional significance for energy fuel homeostasis. The following studies examined whether populations of NADPH-d-positive neurons in the hypothalam...

journal_title：Neuroendocrinology

authors： Briski KP,Sylvester PW

更新日期：1999-03-01 00:00:00

abstract：:Unlike rats, but similar to primates, guinea pigs exhibit prolonged function of the corpus luteum and elevated progesterone secretion after ovulation. The gonadotropins, estrogen (E) and progesterone (P) have been examined throughout the guinea pig estrous cycle. However, neither prolactin secretion nor its regulation...

journal_title：Neuroendocrinology

authors： Bethea CL,Hess DL,Widmann AA,Henningfeld JM

更新日期：1995-06-01 00:00:00

abstract：:We have found thyroxine 5'-deiodinase in rat posterior pituitary. The isozyme pattern was different in intermediate and neural lobes. The former contained only type I enzyme. In the neural lobe, in euthyroidism only type I was found while in hypothyroidism type II was a prominent form. Since type II 5'-deiodinase has ...

journal_title：Neuroendocrinology

authors： Tanaka K,Murakami M,Greer MA

更新日期：1987-12-01 00:00:00

abstract：:The effects of ablation of the nucleus medianus on drinking and vasopressin secretion were studied in male Long-Evans rats. The amount of water drunk in 1 h was assessed after subcutaneous injection of 5.8% NaCl (13.34 mosm/kg) or of angiotensin II (1.5 mg/kg). In a separate test with no water available, plasma vasopr...

journal_title：Neuroendocrinology

authors： Mangiapane ML,Thrasher TN,Keil LC,Simpson JB,Ganong WF

更新日期：1983-07-01 00:00:00

abstract：:The present study was designed to investigate the role of glucocorticoids in mediating the stimulatory effect of interleukin-1 (IL-1) upon the adrenocortical (AC) axis. Intact male rats were injected with either vehicle or dexamethasone (DEX) (5-50 micrograms/100 g b.w.) and were subsequently exposed to ether stress o...

journal_title：Neuroendocrinology

authors： Weidenfeld J,Abramsky O,Ovadia H

更新日期：1989-12-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：:Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...

journal_title：Neuroendocrinology

authors： González-Parra S,Chowen JA,García-Segura LM,Argente J

更新日期：1996-01-01 00:00:00

abstract：:A reproductive facet of ghrelin, a stomach-derived orexigenic peptide involved in energy homeostasis, has been recently suggested, and predominantly inhibitory effects of ghrelin upon luteinizing hormone (LH) secretion have been demonstrated in rat models. Yet, the modulatory actions of ghrelin on the gonadotropic axi...

journal_title：Neuroendocrinology

authors： Fernández-Fernández R,Tena-Sempere M,Navarro VM,Barreiro ML,Castellano JM,Aguilar E,Pinilla L

更新日期：2005-01-01 00:00:00

abstract：:In the Siberian hamster the pituitary content of bioassayable MSH has been shown to be seasonally variable, being greater during the long days of spring and summer than during the short days of autumn and winter. Similar changes in the pituitary content of both bioassayable MSH and immunoreactive alpha MSH can be indu...

journal_title：Neuroendocrinology

authors： Logan A,Weatherhead B

更新日期：1980-05-01 00:00:00

abstract：:Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...

journal_title：Neuroendocrinology

authors： Terracciano F,Capone A,Montori A,Rinzivillo M,Partelli S,Panzuto F,Pilozzi E,Arcidiacono PG,Sette C,Capurso G

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. AIM:To evaluate the clinicopathological features and therapeutic outcomes of CP diagnosed in the elderly. PATIENTS AND METHODS:A retrospective, multicenter, national study of C...

journal_title：Neuroendocrinology

authors： Iglesias P,Nocete I,Moure Rodríguez MD,Venegas-Moreno E,Ares J,Biagetti B,Rodríguez Berrocal V,Guerrero-Pérez F,Vicente A,Villar-Taibo R,Cordido F,Paja M,Glerean M,González Rivera N,Dios Fuentes E,Blanco C,Alvaréz-Escolá

更新日期：2020-10-09 00:00:00

abstract：:The influence of catecholamines (CA) on hypothalamic somatostatin (HPT-SRIF) was investigated in rats by using several drugs which interfere with brain CA metabolism. Depletion of brain CA stores by alpha-methyl-rho-tyrosine (AMT) increased HPT-SRIF, while augmented brain CA levels following L-dopa administration decr...

journal_title：Neuroendocrinology

authors： Torres I,Guaza C,Fernandez-Durango R,Borrell J,Charro AL

更新日期：1982-01-01 00:00:00

abstract：:Brain angiotensin II (AII) receptors play a role in the regulation of luteinizing hormone release. This action is thought to involve luteinizing hormone-releasing hormone containing neurons in the preoptic-anterior hypothalamic (POAH) area of the brain. Previous studies have demonstrated a discrete locus of AII recept...

journal_title：Neuroendocrinology

authors： Grove KL,Cook VI,Speth RC

更新日期：1992-08-01 00:00:00

abstract：:The effects of ovarian steroids on baseline blood pressure and on changes of mean arterial pressure in response to centrally administered angiotensin II, prostaglandin E1, and prostaglandin E2 were examined. Ovariectomized rats treated with estradiol or progesterone showed no change of resting blood pressures relative...

journal_title：Neuroendocrinology

authors： Skoog KM,Kenney NJ

更新日期：1983-02-01 00:00:00

abstract：:The effects of (D-Met2,Pro5)-enkephalinamide--a superactive enkephalin analogue--on the preovulatory discharge of gonadotrophic hormones and on ovulation were investigated. Injection of the opioid (16 nmol) into a lateral cerebral ventricle of regularly cycling female rats immediately before the critical period on the...

journal_title：Neuroendocrinology

authors： Köves K,Marton J,Molnár J,Halász B

更新日期：1981-02-01 00:00:00

abstract：:An in vitro perifusion system was used to investigate immunoreactive beta-endorphin (beta-END-I) release from adult human hypothalami in response to dopamine (DA) and the DA receptor antagonist haloperidol (HAL). Administration of a 1 microM pulse of DA consistently elicited a mean (+/- SE) 88 +/- 9% increase (p less ...

journal_title：Neuroendocrinology

authors： Rasmussen DD,Liu JH,Wolf PL,Yen SS

更新日期：1987-03-01 00:00:00

abstract：:In 2016, the third version of guidelines for the diagnosis and treatment of neuroendocrine tumors (NETs) has been published by the European Neuroendocrine Tumor Society (ENETS). These guidelines reflect the progress in treatment of NETs, and by comparing the newest guidelines with the first guidelines of 2001, this pr...

journal_title：Neuroendocrinology

authors： Zandee WT,de Herder WW

更新日期：2018-01-01 00:00:00

abstract：:The role of endogenous opiate peptides in the mesencephalic central gray (MCG) and their possible interactions with gonadotropin-releasing hormone (GnRH) in the regulation of lordosis behavior was assessed in ovariectomized, estrogen-treated and estrogen-progesterone-treated female rats. Lordosis behavior triggered by...

journal_title：Neuroendocrinology

authors： Sirinathsinghji DJ

更新日期：1984-09-01 00:00:00

abstract：:Somatostatin (ST) inhibits gastrointestinal motility and exocrine and endocrine secretions. In animals, ST has been demonstrated to decrease food intake. We investigated, in a randomized double-blind investigation in 10 healthy humans, the effects of an intravenous ST infusion compared to saline on subjective hunger f...

journal_title：Neuroendocrinology

authors： Lieverse RJ,Jansen JB,Masclee AM,Lamers CB

更新日期：1995-02-01 00:00:00

abstract：:We measured the concentration of oxytocin and vasopressin in microdissected areas of the hypothalamus and posterior pituitary in weanling and adult female rats. Oxytocin concentration was significantly less in adult rats as compared to weanling rats in the supraoptic nucleus, median eminence, and retrochiasmatic area ...

journal_title：Neuroendocrinology

authors： Jackson R,George JM

更新日期：1980-08-01 00:00:00