Skeletal diseases in Cushing's syndrome: osteoporosis versus arthropathy.

abstract：:Chronic administration of the mineralocorticoid deoxycorticosterone acetate (DOCA) induces a steady and robust increase in salt appetite and plasma Na(+) over the course of treatment. Interestingly, salt appetite behavior persists in rats even with elevated plasma Na(+) levels. Since there is evidence that the pathway...

journal_title：Neuroendocrinology

authors： Lucas LR,Pompei P,McEwen BS

更新日期：2000-06-01 00:00:00

abstract：:Previous studies have indicated that 30 min of swimming in room temperature water is a potent stimulus for the secretion of beta-endorphin (beta E) from the intermediate lobe (IL) of the pituitary in rodents. Repeated daily challenge with this paradigm over days to weeks leads to a progressive increase in proopiomelan...

journal_title：Neuroendocrinology

authors： Young EA,Bronstein D,Akil H

更新日期：1993-09-01 00:00:00

abstract：:VIP stimulated prolactin secretion from incubated rat hemipituitaries. Under the same conditions, the secretion of GH, LH, FSH was not affected. The stimulation of prolactin was dose-dependent, with an apparent affinity of VIP of 10.9 +/- 3.1 nM and a maximal stimulation of 57.7 +/- 4.2%. Secretin, a structurally rela...

journal_title：Neuroendocrinology

authors： Enjalbert A,Arancibia S,Ruberg M,Priam M,Bluet-Pajot MT,Rotsztejn WH,Kordon C

更新日期：1980-09-01 00:00:00

abstract：:Amygdalotomized, sham-operated and intact wild-derived house mice of both sexes were group-caged (8-10) or singly caged for 3 weeks. The weights of ovaries (p is less than 0.05) and uteri (p is less than 0.01) were less in intact and sham-operated grouped females compared to singly caged intact and amygdalotomized fem...

journal_title：Neuroendocrinology

authors： Pasley JN,Powell EW,Cernosek RM,Cernosek SF

更新日期：1978-01-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP), a prolactin (PRL)-releasing factor, has been shown to be synthesized within the anterior pituitary. To test the hypothesis that estrogens increase PRL secretion, at least in part, by stimulating VIP secretion, the concentrations of VIP, peptide histidine isoleucine (PHI) and prepro...

journal_title：Neuroendocrinology

authors： Lam KS,Srivastava G,Lechan RM,Lee T,Reichlin S

更新日期：1990-11-01 00:00:00

abstract：:Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...

journal_title：Neuroendocrinology

authors： González-Parra S,Chowen JA,García-Segura LM,Argente J

更新日期：1996-01-01 00:00:00

abstract：:The present study investigates the role of melanotrope proopiomelanocortin-derived peptide in the interrenal stress response to different stressors in male gilthead sea bream, Sparus aurata. Plasma cortisol and acetyl salmon endorphin (acetyl s-EP), as well as pituitary acetyl s-EP contents, were measured during two s...

journal_title：Neuroendocrinology

authors： Mosconi G,Gallinelli A,Polzonetti-Magni AM,Facchinetti F

更新日期：1998-08-01 00:00:00

abstract：:In order to search for candidate genes related to pituitary adenoma aggressiveness, the present investigation was intended to compare the mRNA expression profile from a pool of four nonfunctional pituitary adenomas (NFPA) with a spinal cord metastasis of a nonfunctional pituitary carcinoma (MNFPC). The metallothionein...

journal_title：Neuroendocrinology

authors： Giorgi RR,Correa-Giannella ML,Casarini AP,Machado MC,Bronstein MD,Cescato VA,Giannella-Neto D

更新日期：2005-01-01 00:00:00

abstract：:The role of endogenous opiate peptides in the mesencephalic central gray (MCG) and their possible interactions with gonadotropin-releasing hormone (GnRH) in the regulation of lordosis behavior was assessed in ovariectomized, estrogen-treated and estrogen-progesterone-treated female rats. Lordosis behavior triggered by...

journal_title：Neuroendocrinology

authors： Sirinathsinghji DJ

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:68Gallium DOTA-PET imaging is preferable to standard somatostatin receptor scintigraphy where available; however, its role in the management of lung carcinoid tumours (LC) remains unclear. METHODS:All consecutive patients with histologically confirmed LC from two ENETS Centres of Excellence were identified ...

journal_title：Neuroendocrinology

authors： Lamarca A,Pritchard DM,Westwood T,Papaxoinis G,Nonaka D,Vinjamuri S,Valle JW,Manoharan P,Mansoor W

更新日期：2018-01-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:An initial study was performed to ascertain the effects of anisomycin, a reversible inhibitor of protein synthesis, on pulsatile luteinizing hormone (LH) release in adult, ovarietomized (OVX) rats. For this experiment, rats OVX 3-4 weeks earlier were fitted with indwelling atrial cannulae. On the next day (approximate...

journal_title：Neuroendocrinology

authors： DePaolo LV

更新日期：1989-07-01 00:00:00

abstract：:The role of endogenous opioid peptides in the control of gonadotropin-releasing hormone pulse generator activity was examined in long-term ovariectomized goats by recording the hypothalamic multiple-unit activity specifically associated with pulsatile luteinizing hormone secretion (MUA volleys). Administration of nalo...

journal_title：Neuroendocrinology

authors： Ito K,Tanaka T,Mori Y

更新日期：1993-04-01 00:00:00

abstract：:Central or systemic administration of morphine disrupts maternal behavior in steroid-primed, pup-induced virgin and lactating rats. Morphine, the prototypical mu agonist, also interacts with different opioid receptor subtypes. The present study examined the effectiveness of five receptor-selective agonists, in additio...

journal_title：Neuroendocrinology

authors： Mann PE,Kinsley CH,Bridges RS

更新日期：1991-05-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：:When fetal preoptic area (POA) brain grafts that contain gonadotropin-releasing hormone cells are transplanted into the third ventricle of adult female hypogonadal mice, the animals respond with sexual maturation, persistent estrus, and the ability to ovulate reflexively after mating. However, the absence of normal sp...

journal_title：Neuroendocrinology

authors： Gibson MJ,Kokoris GJ,Silverman AJ

更新日期：1988-08-01 00:00:00

abstract：:After in vivo treatment, progesterone initially decreases tyrosine hydroxylase (TH) activity in the TIDA neurons, but subsequently increases TH activity with prolonged treatment. In order to explore the cellular mechanism for progesterone's effect, this study examined the acute inhibitory action of progesterone on TH ...

journal_title：Neuroendocrinology

authors： Arbogast LA,Voogt JL

更新日期：2002-05-01 00:00:00

abstract：:We studied the effect that beta-endorphin (beta END) might have at the median eminence (ME) on luteinizing hormone (LH)-releasing hormone (LHRH) during the ovulatory cycle of domestic hens. Thus, we assessed (a) the immunocytochemical distribution of beta END and LHRH in the hen ME, (b) the temporal changes in ME and ...

journal_title：Neuroendocrinology

authors： Contijoch AM,Malamed S,Sarkar DK,Advis JP

更新日期：1993-01-01 00:00:00

abstract：:Electrical stimulation in the subfornical organ (SFO) alters the excitability of antidromically identified paraventricular nucleus neurons. Extracellular recordings demonstrate that the dominant effect of single stimuli delivered to the SFO on neurohypophyseal oxytocin and vasopressin containing neurons is an increase...

journal_title：Neuroendocrinology

authors： Ferguson AV,Day TA,Renaud LP

更新日期：1984-11-01 00:00:00

abstract：:Hypophysitis is a relatively rare disease that exerts a strong autoimmune component encompassing different etiologies. Immunomodulatory drugs, such as interferon-α, are known to rarely induce hypophysitis. In recent years, a large number of new biological and immunomodulatory agents have been introduced into clinical ...

journal_title：Neuroendocrinology

authors： Angelousi A,Chatzellis E,Kaltsas G

更新日期：2018-01-01 00:00:00

abstract：:Although glutamate is the predominant excitatory amino acid in the vertebrate central nervous system (CNS) where it affects a variety of physiological processes and pathophysiological states, the role that glutamate receptors may play outside the CNS has not been clearly established. In the present study, the effects ...

journal_title：Neuroendocrinology

authors： Giovannucci DR,Stuenkel EL

更新日期：1995-08-01 00:00:00

abstract：:Pulsatile gonadotropin-releasing hormone (GnRH) release from the median eminence is critical for the appropriate function of the pituitary gonadotropes and for the generation of a preovulatory gonadotropin surge. The mechanisms by which many GnRH axon terminals are synchronized to release GnRH in a coordinated fashion...

journal_title：Neuroendocrinology

authors： Hosny S,Jennes L

更新日期：1998-02-01 00:00:00

abstract：:The known occurrence of opiates in the adrenals stimulated us to determine whether Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2), an endogenous peptide that can act as an antiopiate, is present in these glands and whether adrenalectomy affects its concentrations in plasma. The presence of Tyr-MIF-1 in the adrenals of the rat was sh...

journal_title：Neuroendocrinology

authors： Kastin AJ,Fabre L,Banks WA,Zadina JE

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...

journal_title：Neuroendocrinology

authors： Poletini MO,Kennett JE,McKee DT,Freeman ME

更新日期：2010-01-01 00:00:00

abstract：:Steroid autoradiography was undertaken to determine the neuroanatomical loci which might be involved in the activation of steroid-sensitive behaviors in the Japanese quail (Coturnix japonica). Male and female quail were either surgically gonadectomized or photically regressed and implanted with androgen or estrogen to...

journal_title：Neuroendocrinology

authors： Watson JT,Adkins-Regan E

更新日期：1989-01-01 00:00:00

abstract：:Hypothalamic dopamine (DA) tonically inhibits prolactin (PRL) release from the anterior pituitary gland. Transient escapes from this DA tone elicit a pronounced potentiation of the PRL-releasing action of secretagogues such as thyrotropin-releasing hormone (TRH). Previous evidence has suggested that modulation of Ca(2...

journal_title：Neuroendocrinology

authors： del Mar Hernández M,García Ferreiro RE,García DE,Hernández ME,Clapp C,Martínez de la Escalera G

更新日期：1999-07-01 00:00:00

abstract：:17 alpha-hydroxyprogesterone (up to 200 mug/day) and 11 beta-hydroxyandrostenedione (up to 500 mug) had no effect on PMS-induced ovulation in intact immature rats. 10 mug/day of testosterone propoinate (TP) on days 28-30 of life decreased the percent of animals ovulating and the number of ova produced; this effect per...

journal_title：Neuroendocrinology

authors： Hagino N,Goldzieher JW

更新日期：1975-01-01 00:00:00

abstract：:Glass microknife lesions and immunocytochemistry were used to evaluate luteinizing hormone-releasing hormone (LH-RH)- and somatostatin (SS)-immunoreactive pathways from the preoptic region to the rat median eminence. Cuts were so placed that axons of more caudally located neurons in the periventricular hypothalamic ar...

journal_title：Neuroendocrinology

authors： Jew JY,Léránth C,Arimura A,Palkovits M

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND/AIMS:Estrogen receptor-alpha (ER alpha) splice variants are important for understanding estrogen effects on the brain and estrogen therapy pitfalls. We addressed the question whether a novel ER alpha splice variant TADDI is expressed at the protein level in the human brain and whether it changes in relation ...

journal_title：Neuroendocrinology

authors： Ishunina TA,Swaab DF

更新日期：2009-01-01 00:00:00

abstract：:The postnatal development of the luteinizing hormone-releasing hormone (LHRH) system in male and female rats was investigated using light microscopic immunocytochemistry. An identical number of immunoreactive LHRH cells (about 1,300) was observed for males and females throughout development. Two LHRH cell types, based...

journal_title：Neuroendocrinology

authors： Wray S,Hoffman G

更新日期：1986-01-01 00:00:00