Effects of amygdaloid lesions on reproductive function of grouped caged mice.

Abstract:

:Amygdalotomized, sham-operated and intact wild-derived house mice of both sexes were group-caged (8-10) or singly caged for 3 weeks. The weights of ovaries (p is less than 0.05) and uteri (p is less than 0.01) were less in intact and sham-operated grouped females compared to singly caged intact and amygdalotomized females. The weight of the reproductive organs in amygdalotomized grouped female mice was not different from singly caged controls. Body weights among amygdalotomized grouped females were heavier (p is less than 0.05) than singly caged controls. Seminal vesicle weights of intact and sham-operated grouped males were less (p is less than 0.05) than that of singly caged controls and grouped amygdalotomized males. Plasma LH values from the various groups coincided with the morphological data. These results support the hypothesis that increased population density impairs reproductive function in mammals. Perhaps the effects of decreased pituitary-gonadal function associated with overcrowding are mediated via amygdalar nuclei.

journal_name

Neuroendocrinology

journal_title

Neuroendocrinology

authors

Pasley JN,Powell EW,Cernosek RM,Cernosek SF

doi

10.1159/000122731

subject

Has Abstract

pub_date

1978-01-01 00:00:00

pages

77-83

issue

2

eissn

0028-3835

issn

1423-0194

journal_volume

25

pub_type

杂志文章
  • Luteinising hormone secretion from the perifused ovine pars tuberalis and pars distalis: effects of gonadotropin-releasing hormone and melatonin.

    abstract::It is not known where melatonin acts to influence the neuroendocrine axis of seasonally breeding mammals. However, since the pars tuberalis (PT) contains the highest density of melatonin receptors, this adenohypophyseal subdivision is a potential target. Gonadotropes are the only immunocytochemically detectable adenoh...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000127247

    authors: Skinner DC,Robinson JE

    更新日期:1997-10-01 00:00:00

  • Repetitive injections of L-glutamic acid, in contrast to those of N-methyl-D,L-aspartic acid, fail to elicit sustained hypothalamic GnRH release in the prepubertal male rhesus monkey (Macaca mulatta).

    abstract::The purpose of the present study was to examine whether repetitive intravenous injections of L-glutamic acid (Glu), like those of N-methyl-D,L-aspartic acid (NMA), are able to elicit a sustained train of gonadotropin releasing hormone (GnRH) discharges from the hypothalamus of the prepubertal male monkey. In order to ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126186

    authors: Medhamurthy R,Gay VL,Plant TM

    更新日期:1992-06-01 00:00:00

  • Olfactory bulbs influence testosterone feedback on gonadotropin secretion in male hamsters on long or short photoperiod.

    abstract::Previous studies have shown that prepubertal olfactory bulbectomy will prevent the testicular regression associated with short photoperiod in golden hamsters. The gonadal regression which normally occurs in hamsters on short photoperiod is known to be due in part to an increased responsiveness of the reproductive neur...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000124839

    authors: Pieper DR,Unthank PD,Shuttie DA,Lobocki CA,Swann JM,Newman S,Subramanian MG

    更新日期:1987-10-01 00:00:00

  • Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.

    abstract::In previous studies, we have shown that male Wistar rats exposed to a single inescapable stressor session (15 min restraint) exhibited 24 h later an anxiogenic-like behavior in the elevated plus-maze (EPM), which was reversed by inhibition of corticosterone (CS) synthesis with metyrapone (75 mg/kg i.p.) 3 h before str...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000054643

    authors: Calvo N,Volosin M

    更新日期:2001-04-01 00:00:00

  • Subfornical organ lesions reduce the pressor effect of systemic angiotensin II.

    abstract::The pressor effect of intravenous angiotensin II (AII) was compared in the unrestrained rat before and after electrolytic lesions of the subfornical organ (SFO), the circumventricular organ of the dorsal third cerebral ventricle. Abdominal aortic and venal caval catheters were used to measure arterial pressure and to ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123107

    authors: Mangiapane ML,Simpson JB

    更新日期:1980-12-01 00:00:00

  • Elevated brain glucose and glycogen concentrations in an animal model of depression.

    abstract:INTRODUCTION:Recent data indicate that there is a link between depression and diabetes and that excess glucocorticoids may play an underlying role in the pathogenesis of both of these diseases. The aim of the present study was to determine whether there are any alterations in glucose, glycogen, glucose transporters, in...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000368607

    authors: Detka J,Kurek A,Basta-Kaim A,Kubera M,Lasoń W,Budziszewska B

    更新日期:2014-01-01 00:00:00

  • Hyperprolactinemia induced by pituitary isografts suppresses the priming effect of LH-releasing hormone in normal and hypogonadal mice.

    abstract::We have investigated the effects of hyperprolactinemia, produced by pituitary isografts under the kidney capsule (16-20 days), on the LH releasing action and priming effect of LH-releasing hormone (LHRH) in normal and hypogonadal (hpg) female mice. The pituitary grafts increased the plasma prolactin concentrations abo...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000124585

    authors: Lewis CE,Fink G,Dow RC,Morris JF

    更新日期:1986-01-01 00:00:00

  • The Neuroendocrine and Metabolic Outcomes of Bariatric Surgery Depend on Presurgical Control over Eating.

    abstract:BACKGROUND:The outcomes of bariatric surgery are very irregular and mostly unpredictable. The search for variables of predictive value is encouraged to help preventing therapeutic failures. OBJECTIVE:We aimed to confirm the hypothesis that preexisting eating behaviors could predict neuroendocrine and metabolic outcome...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000500687

    authors: Muñoz-Rodríguez JR,Rodríguez-Cano T,Polo F,Sáenz-Mateos L,Agarrado A,Segura E,Casas G,Martín-Fernández J,Beato-Fernández L,Salas E,González-Martín C,Alguacil LF

    更新日期:2020-01-01 00:00:00

  • Alpha-melanocyte-stimulating hormone through melanocortin-4 receptor inhibits nitric oxide synthase and cyclooxygenase expression in the hypothalamus of male rats.

    abstract::There is evidence that alpha-melanocyte-stimulating hormone (alpha-MSH) has immunomodulatory and anti-inflammatory actions within the brain. In this study, we tested whether these actions are due to inhibition of the synthesis of nitric oxide (NO) and prostaglandins induced by lipopolysaccharide (LPS). Since melanocor...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000079321

    authors: Caruso C,Mohn C,Karara AL,Rettori V,Watanobe H,Schiöth HB,Seilicovich A,Lasaga M

    更新日期:2004-01-01 00:00:00

  • Neuropeptide Y gene expression in male sheep: influence of photoperiod and testosterone.

    abstract::The frequency of pulsatile release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) is high in the breeding season and low in the nonbreeding season. These alterations in the patterns of GnRH and LH release are due to an interaction of daylength and gonadal steroid negative feedback. A vast amount...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000076631

    authors: Dobbins A,Lubbers LS,Jackson GL,Kuehl DE,Hileman SM

    更新日期:2004-02-01 00:00:00

  • Growth hormone-secreting tumors: genetic aspects and data from animal models.

    abstract::Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,评审

    doi:10.1159/000095525

    authors: Lytras A,Tolis G

    更新日期:2006-01-01 00:00:00

  • GABA neuron systems in hypothalamus and the pituitary gland. Immunohistochemical demonstration using antibodies against glutamate decarboxylase.

    abstract::The distribution of gamma-aminobutyric acid (GABA) nerve fibers and cell bodies in the rat hypothalamus and pituitary gland was immunohistochemically examined using antibodies against the GABA-synthesizing enzyme glutamate decarboxylase (GAD). The dense network of GAD-positive nerve fibers was observed to be essential...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123288

    authors: Vincent SR,Hökfelt T,Wu JY

    更新日期:1982-02-01 00:00:00

  • Subfornical organ connections with septal neurons projecting to the median eminence.

    abstract::We have examined the effect of electrical stimulation in the subfornical organ (SFO) on the activity of neurons in the medial septum and diagonal band of Broca (MS-DBB) which project to the median eminence in the rat. Previous studies have suggested that septal neurons with such projections are luteinizing hormone rel...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000124991

    authors: Donevan SD,Ferguson AV

    更新日期:1988-07-01 00:00:00

  • Use of prolactin receptor antagonist to better understand prolactin regulation of pituitary homeostasis.

    abstract::The anterior pituitary is permanently regulated by processes of apoptosis and proliferation in order to maintain tissue homeostasis. Several factors have been implicated in this regulation and lately, prolactin (PRL) has been included into that list. However, since PRL is secreted by anterior pituitary lactotropes, th...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,评审

    doi:10.1159/000354701

    authors: Ferraris J,Bernichtein S,Pisera D,Goffin V

    更新日期:2013-01-01 00:00:00

  • Determination of guanine nucleotide sensitivity of [125-I]-neuropeptide Y binding in the rat pituitary gland by quantitative autoradiography.

    abstract::[125I]-neuropeptide Y receptors were characterized in the rat pituitary gland using quantitative autoradiography. Scatchard analysis of saturation isotherms showed high affinity (Kd 8.5 x 10(-11) M) and single class of binding sites (Bmax 0.22 pmol/mg of protein) in the posterior lobe of the pituitary gland, with no s...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125608

    authors: Torda T,Saavedra JM

    更新日期:1990-10-01 00:00:00

  • Grade Increases in Gastroenteropancreatic Neuroendocrine Tumor Metastases Compared to the Primary Tumor.

    abstract:BACKGROUND/AIM:The neuroendocrine tumor (NET) proliferation-based grading system (ENETS/WHO) for gastroenteropancreatic (GEP) tumors has proved reliable for prognostic stratification. To date, concerns exist regarding Ki-67 heterogeneity within the tumor and little is known on whether grade varies between primary and s...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000439434

    authors: Grillo F,Albertelli M,Brisigotti MP,Borra T,Boschetti M,Fiocca R,Ferone D,Mastracci L

    更新日期:2016-01-01 00:00:00

  • Connections of medial preoptic neurons with the median eminence and amygdala. An electrophysiological study in the rat.

    abstract::An electrophysiological investigation was conducted on the connection of medial preoptic neurons with the median eminence and the basal and corticomedial amygdala in pentobarbital anesthesized male Sprague-Dawley rats. Of 411 medial preoptic neurons tested with median eminence stimuli, antidromic responses (mean laten...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123237

    authors: Layton BS,Lafontaine S,Renaud LP

    更新日期:1981-01-01 00:00:00

  • Restoration of pituitary prolactin synthesis and release by the administration of morphine to rats bearing a transplanted prolactin-secreting tumor.

    abstract::Rats bearing transplanted prolactin-secreting tumors are known to have very high prolactin levels in the serum, reduced hypothalamic opiate concentrations, increasing hypothalamic dopamine synthesis and increased hypophyseal portal blood dopamine levels. Further, it has been shown that incubation in 3H-leucine of ante...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123211

    authors: Login IS,Nagy I,MacLeod RM

    更新日期:1981-08-01 00:00:00

  • DIETARY FIBERS AND PROTEINS MODULATE BEHAVIOR VIA THE ACTIVATION OF INTESTINAL GLUCONEOGENESIS.

    abstract:INTRODUCTION:Several studies have suggested that diet, especially one enriched in microbiota-fermented fibers or fat, regulates behavior. The underlying mechanisms are currently unknown. We previously reported that certain macronutrients (fermentable fiber and protein) regulate energy homeostasis via the activation of ...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000514289

    authors: Sinet F,Soty M,Zemdegs J,Guiard B,Estrada J,Malleret G,Silva M,Mithieux G,Gautier-Stein A

    更新日期:2021-01-11 00:00:00

  • Progesterone, but not LHRH or prostaglandin E2, induces sequential inhibition of lordosis to various lordogenic agents.

    abstract::In experiment I we studied the capacity of progesterone (P) and two nonsteroidal agents that activate lordosis, but do not bind to the progestin receptor (PR), i.e. luteinizing hormone-releasing hormone (LHRH) and prostaglandin E2 (PGE2) to induce sequential inhibition (SI) in ovariectomized estradiol-primed rats. The...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126457

    authors: González-Mariscal G,Melo AI,Beyer C

    更新日期:1993-05-01 00:00:00

  • Relative efficiency of neural firing patterns for vasopressin release in vitro.

    abstract::Single rat neurohypophyses were impaled on a platinum electrode, perifused with isotonic medium and fractions of perifusate collected each minute. Arginine vasopressin content of the fractions was measured by radioimmunoassay. The basal release of arginine vasopressin varied from 50 to 350 pg (0.02-0.14 mU/min) betwee...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123248

    authors: Bicknell RJ,Leng G

    更新日期:1981-11-01 00:00:00

  • Activation of an inwardly rectifying K+ conductance by orphanin-FQ/nociceptin in vasopressin-containing neurons.

    abstract::The orphanin-FQ/nociceptin (OFQ/N) receptor (previously, ORL1, LC132) has been shown to be coupled to an inwardly rectifying K+ conductance in several neuronal populations. Although OFQ/N receptor mRNA is densely expressed in the supraoptic nucleus (SON), little is known about its coupling to effector system(s). The p...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000054441

    authors: Slugg RM,Rønnekleiv OK,Grandy DK,Kelly MJ

    更新日期:1999-05-01 00:00:00

  • Chromogranin A in diagnosing and monitoring patients with gastroenteropancreatic neuroendocrine neoplasms: a large series from a single institution.

    abstract:BACKGROUND/AIMS:Plasma chromogranin A (CgA) is the most widely used biochemical biomarker in the diagnostic workup and follow-up of gastroenteropancreatic neuroendo- crine neoplasms (GEP-NENs). Herein, we assessed the clinical utility of CgA in diagnosing and monitoring a large series of GEP-NENs. PATIENTS AND METHODS...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000369818

    authors: Massironi S,Rossi RE,Casazza G,Conte D,Ciafardini C,Galeazzi M,Peracchi M

    更新日期:2014-01-01 00:00:00

  • Bombesin-like immunoreactivity in the forebrain and pituitary and regulation of anterior pituitary hormone release by bombesin in goldfish.

    abstract::The presence and distribution of bombesin (BBS)/gastrin-releasing peptide (GRP)-like immunoreactivity (IR) was examined in the goldfish pituitary and forebrain. BBS/GRP-like IR nerve fibres were consistently observed throughout the pituitary neurointermediate lobe (NIL); occasionally, BBS/GRP-like material was localiz...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126858

    authors: Himick BA,Peter RE

    更新日期:1995-04-01 00:00:00

  • Modulation of hippocampal glucocorticoid and mineralocorticoid receptor mRNA expression by amygdaloid kindling.

    abstract::In situ hybridization was used to examine the effects of amygdala kindling on the expression of mRNAs for mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) in the rat hippocampus. Kindling increased MR mRNA levels in the dentate gyrus of the hippocampus 4 h after the last seizure, and these levels rem...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000126691

    authors: Clark M,Smith MA,Weiss SR,Post RM

    更新日期:1994-05-01 00:00:00

  • Influence of ACTH on tyrosine hydroxylase activity in the locus coeruleus of mouse brain.

    abstract::Tyrosine hydroxylase activity in noradrenergic neurons of the locus coeruleus was found to rise in bilaterally adrenalectomized adult mice, with maximum increase of the enzyme activity (52% above control) occurring 7 days after the surgery. No such increase of tyrosine hydroxylase activity was found in dopaminergic ne...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000123902

    authors: Markey KA,Sze PY

    更新日期:1984-04-01 00:00:00

  • Everolimus in Combination with Octreotide Long-Acting Repeatable in a First-Line Setting for Patients with Neuroendocrine Tumors: A 5-Year Update.

    abstract:BACKGROUND:We previously presented data of this multicentric, phase II study showing that everolimus plus octreotide long-acting repeatable (LAR) for advanced neuroendocrine neoplasms (NENs), in the first line setting, is an active and safe treatment. We now present updated data at 5 years. METHODS:Patients with advan...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000479587

    authors: Bajetta E,Catena L,Pusceddu S,Spada F,Iannacone C,Sarno I,Di Menna G,Dottorini L,Marte AM

    更新日期:2018-01-01 00:00:00

  • The endogenous stimulatory rhythm regulating prolactin secretion is present in the lactating rat.

    abstract::Prolactin (PRL) secretion in the female rat is regulated by an endogenous stimulatory rhythm (ESR), which is normally under the tonic inhibition of dopamine (DA). The ESR consists of a nocturnal (N) component which peaks at approximately 03.00 h, and a diurnal (D) component which peaks at approximately 17.00 h. This E...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000125694

    authors: Arey BJ,Kanyicska B,Freeman ME

    更新日期:1991-01-01 00:00:00

  • Cells of proopiomelanocortin lineage from the rodent anterior pituitary lack sexually dimorphic expression of neurofilaments.

    abstract::Lactotrophs, gonadotrophs, thyrotrophs and somatotrophs of the rat anterior pituitary (AP) express 68-kDa neurofilaments (NF68) and other neuronal markers. NF68 expression in the AP appears to be estrogen-dependent, but its significance is unknown. The aims of this work were: (1) to establish the expression pattern of...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000095548

    authors: Fiordelisio T,Millán-Aldaco D,Hernández-Cruz A

    更新日期:2006-01-01 00:00:00

  • Effect of L-dopa on plasma TSH levels in primary hypothyroidism.

    abstract::Plasma TSH responses after an i.v. injection of 100 mg of L-dopa were evaluated by radioimmunoassay in 4 normal euthyroid subjects and in 8 patients with primary hypothyroidism. In agreement with previous results, no variations to plasma TSH levels were observed in the euthyroid subjects. In contrast, in primary hypo...

    journal_title:Neuroendocrinology

    pub_type: 杂志文章

    doi:10.1159/000122350

    authors: Minozzi M,Faggiano M,Lombardi G,Carella C,Criscuolo T,Scapagnini U

    更新日期:1975-01-01 00:00:00