Connections of medial preoptic neurons with the median eminence and amygdala. An electrophysiological study in the rat.

abstract：:Using a high-performance liquid chromatography (HPLC) system coupled with an electrochemical detector, the concentrations of dopamine (DA) and 5-hydroxytryptamine (5-HT) and their major specific metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindole-3-acetic acid (5-HIAA), respectively, were measured i...

journal_title：Neuroendocrinology

authors： Kerdelhué B,Bojda F,Lesieur P,Pasqualini C,el Abed A,Lenoir V,Douillet P,Chiueh MC,Palkovits M

更新日期：1989-02-01 00:00:00

abstract：:A double immunocytochemical procedure, with two different chromogens, was used to compare the respective distribution of estrogen receptor-immunoreactive cells and tyrosine hydroxylase-immunoreactive neurons on the same sections of the preoptic region of adult female rainbow trout (Oncorhynchus mykiss). Estrogen recep...

journal_title：Neuroendocrinology

authors： Linard B,Anglade I,Corio M,Navas JM,Pakdel F,Saligaut C,Kah O

更新日期：1996-02-01 00:00:00

abstract：:Measurements of electrical activity and intracellular Ca(2+) levels were performed in perforated-patch clamped GH(3) cells to determine the contribution of large-conductance calcium-activated K(+) (BK) channels to action potential repolarization and size of the associated Ca(2+) oscillations. By examining the dependen...

journal_title：Neuroendocrinology

authors： Miranda P,de la Peña P,Gómez-Varela D,Barros F

更新日期：2003-03-01 00:00:00

abstract：:Estradiol rapidly regulates the activity of arcuate nucleus (ARH) proopiomelanocortin (POMC) neurons that project to the medial preoptic nucleus (MPN) to regulate lordosis. Orphanin FQ/nociceptin (OFQ/N) acts via opioid receptor-like (ORL)-1 receptors to inhibit these POMC neurons. Therefore, we tested the hypothesis ...

journal_title：Neuroendocrinology

authors： Conde K,Meza C,Kelly MJ,Sinchak K,Wagner EJ

更新日期：2016-01-01 00:00:00

abstract：:Neuroanatomical attempts have been made to determine the synapses between luteinizing hormone-releasing hormone (LHRH)-containing neurons and substance P (SP)-containing neurons in the hypothalamus of female rats. Wheat germ agglutinin was injected into the septo-preoptic area (SPA) and found to be incorporated into c...

journal_title：Neuroendocrinology

authors： Tsuruo Y,Kawano H,Hisano S,Kagotani Y,Daikoku S,Zhang T,Yanaihara N

更新日期：1991-03-01 00:00:00

abstract：INTRODUCTION:An increasing number of middle-aged men are being screened for low testosterone levels and the number of prescriptions for various forms of testosterone replacement therapy (TRT) has increased dramatically over the last 10 years. However, the safety of TRT has come into question with some studies suggestin...

journal_title：Neuroendocrinology

authors： Smith C,Contreras-Garza J,Cunningham RL,Wong JM,Vann PH,Metzger D,Kasanga E,Oppong-Gyebi A,Sumien N,Schreihofer DA

更新日期：2020-01-01 00:00:00

abstract：:The effect of catecholamines on plasma levels of immunoreactive ACTH (ACTHi), alpha-MSH (alpha-MSHi), beta-endorphin (beta-ENDi), arginine-vasopressin (AVPi) and of corticosterone (B) was studied in female rats. Intravenous infusion of the specific beta-adrenoceptor-stimulating agent l-isoproterenol in Wistar rats und...

journal_title：Neuroendocrinology

authors： Berkenbosch F,Vermes I,Buijs RM,Tilders FJ

更新日期：1983-08-01 00:00:00

abstract：:Dopaminergic agonists are effective in vivo in inhibiting lactotrope proliferation and prolactin (PRL)-secreting pituitary tumors. The purpose of the present study was to demonstrate in vitro actions of dopaminergic agents on proliferation and cell shape of rat lactotropes. Anterior pituitary cells cultured with serum...

journal_title：Neuroendocrinology

authors： Arita J,Hashi A,Hoshi K,Mazawa S,Suzuki S

更新日期：1998-09-01 00:00:00

abstract：:Insulin-deficient states are associated with an impaired function of the hypothalamic-pituitary-gonadal axis, but the mechanisms underlying hypothalamic alterations in experimental diabetes are still unknown. We investigated the effect of glucose concentrations, in the presence and absence of insulin, on LHRH release ...

journal_title：Neuroendocrinology

authors： Arias P,Rodríguez M,Szwarcfarb B,Sinay IR,Moguilevsky JA

更新日期：1992-09-01 00:00:00

abstract：:Overt Cushing's syndrome is a rare disorder with an annual incidence of 2-3/million of which benign adrenal adenomas account for 0.6/million. The female:male ratio is 3:1. Preliminary data indicate a high proportion of subclinical Cushing's syndrome in certain risk populations such as patients with type 2 diabetes or ...

journal_title：Neuroendocrinology

authors： Steffensen C,Bak AM,Rubeck KZ,Jørgensen JO

更新日期：2010-01-01 00:00:00

abstract：:Central or systemic administration of morphine disrupts maternal behavior in steroid-primed, pup-induced virgin and lactating rats. Morphine, the prototypical mu agonist, also interacts with different opioid receptor subtypes. The present study examined the effectiveness of five receptor-selective agonists, in additio...

journal_title：Neuroendocrinology

authors： Mann PE,Kinsley CH,Bridges RS

更新日期：1991-05-01 00:00:00

abstract：:5-hydroxytryptamine (5-HT) synthesis [accumulation of 5-hydroxytryptophan (5-HTP) following inhibition of aromatic L-amino acid decarboxylase with NSD 1015] and metabolism [concentration of the primary metabolite of 5-HT, 5-hydroxyindole-3-acetic acid (5-HIAA)] were measured in the suprachiasmatic (SCN), medial preopt...

journal_title：Neuroendocrinology

authors： Johnston CA,Demarest KT,Moore KE

更新日期：1984-02-01 00:00:00

abstract：CONTEXT:Early pubertal luteinizing hormone (LH), and by inference gonadotropin-releasing hormone (GnRH), pulse secretion is marked by high nocturnal but low daytime frequency; however, the underlying mechanisms remain unclear. Plasma concentrations of progesterone, the major regulator of GnRH frequency in women, increa...

journal_title：Neuroendocrinology

authors： Collins JS,Marshall JC,McCartney CR

更新日期：2012-01-01 00:00:00

abstract：:The relationship between the steroid hormone 17 beta-estradiol and the muscarinic cholinergic receptors present in the preoptic area (POA), median hypothalamus and posterior hypothalamus of female rats was examined in vitro at various stages of the estrous cycle. Muscarinic receptors varied in a cyclic manner, specifi...

journal_title：Neuroendocrinology

authors： Egozi Y,Kloog Y

更新日期：1985-05-01 00:00:00

abstract：:The incidence of obesity is rapidly escalating and has reached epidemic proportions. In all species, including rodents, humans, and sheep, there is large variation in the degree of weight gain across individuals in response to an obesogenic environment. This individual variation is, at least in part, determined by inn...

journal_title：Neuroendocrinology

authors： Henry BA

更新日期：2017-01-01 00:00:00

abstract：:Hemicastration of male rats produced rapid changes in plasma testosterone (T) levels both in summer and in winter. However, in winter, after unilateral castration, the duration of T maximum decrease was found to be longer, but the compensatory increase of blood T following its drop was more dramatic as compared to the...

journal_title：Neuroendocrinology

authors： Naumenko EV,Shishkina GT

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND/AIM:The mode of action of the somatostatin analog octreotide on neuro-endocrine tumour proliferation is largely unknown. Overexpression of the proto-oncogene Akt/PKB (protein kinase B) has been demonstrated in certain neuro-endocrine tumours: Akt activates downstream proteins including mTOR and p70S6K, which...

journal_title：Neuroendocrinology

authors： Grozinsky-Glasberg S,Franchi G,Teng M,Leontiou CA,Ribeiro de Oliveira A Jr,Dalino P,Salahuddin N,Korbonits M,Grossman AB

更新日期：2008-01-01 00:00:00

abstract：:The effect of stress- or lipopolysaccharide (LPS) endotoxin-induced release of ACTH, beta-endorphin (beta-END) and prolactin (PRL) was investigated in two groups of conscious male rats: (1) Rats pretreated with different H3 receptor agonists, which inhibit neuronal histamine (HA) synthesis and release, and (2) rats wi...

journal_title：Neuroendocrinology

authors： Knigge U,Søe-Jensen P,Jorgensen H,Kjaer A,Møller M,Warberg J

更新日期：1999-01-01 00:00:00

abstract：:Plasma and hypothalamic LHRH was measured by specific radioimmuno-assay in intact and ovariectomized rats, and the values were correlated with peripheral plasma (PP) FSH and LH titers. At most stages of the estrous cycle, plasma LHRH was either undetectable or present at very minimal values. An increase in PP LHRH con...

journal_title：Neuroendocrinology

authors： Wheaton JE,McCann SM

更新日期：1976-01-01 00:00:00

abstract：:In goldfish the two native forms of gonadotropin-releasing hormone (GnRH), salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), stimulate both gonadotropin-II (GTH-II) and growth hormone (GH) release. Modifications of GnRH structure at positions 1, 2, 3, and 6 often result in an antagonist in goldfish, an observation w...

journal_title：Neuroendocrinology

authors： Murthy CK,Turner RJ,Wong AO,Rao PD,Rivier JE,Peter RE

更新日期：1994-06-01 00:00:00

abstract：:Oxytocin receptors are regulated during parturition and lactation. Gonadal steroids are thought to be key players in this regulation. It is not well documented how oxytocin receptor gene expression is regulated in the CNS. In this study we analyzed potential estrogen effects on the oxytocin receptor mRNA levels in som...

journal_title：Neuroendocrinology

authors： Quiñones-Jenab V,Jenab S,Ogawa S,Adan RA,Burbach JP,Pfaff DW

更新日期：1997-01-01 00:00:00

abstract：:We have attempted to elucidate the effect of glucose concentrations on the release of thyrotropin-releasing hormone (TRH), a brain neuropeptide possessing glucoregulatory function, from rat hypothalamic slices in vitro. Rat hypothalamic slices were preincubated for 60 min at 37 degrees C in Krebs-Ringer bicarbonate (K...

journal_title：Neuroendocrinology

authors： Yamaguchi M,Iriuchijima T,Michimata T,Mori M

更新日期：1991-04-01 00:00:00

abstract：:Parturition is initiated in sheep by an increase in the activity of the fetal hypothalamus-pituitary-adrenal (HPA) axis. Prostaglandins, known to augment the activity of this endocrine axis, have long been proposed as involved in the initiation of paturition. We have previously demonstrated that endogenously produced ...

journal_title：Neuroendocrinology

authors： Deauseault D,Giroux D,Wood CE

更新日期：2000-05-01 00:00:00

abstract：:The neurohypophysial peptide hormone [Arg8]vasopressin (AVP) has well documented pressor effects in the periphery. These are mediated by vasopressin receptors (VPRs) of the V1a subtype, expressed by vascular smooth muscle cells, which induce vascular contraction when activated. AVP also has effects on the vasculature ...

journal_title：Neuroendocrinology

authors： Sermasi E,Howl J,Pyner S,Wheatley M,Coote JH

更新日期：1995-12-01 00:00:00

abstract：:In experiment I we studied the capacity of progesterone (P) and two nonsteroidal agents that activate lordosis, but do not bind to the progestin receptor (PR), i.e. luteinizing hormone-releasing hormone (LHRH) and prostaglandin E2 (PGE2) to induce sequential inhibition (SI) in ovariectomized estradiol-primed rats. The...

journal_title：Neuroendocrinology

authors： González-Mariscal G,Melo AI,Beyer C

更新日期：1993-05-01 00:00:00

abstract：:To characterize the short-term ACTH secretion pattern and to investigate factors regulating it, pituitary venous (PV) blood was collected using our nonsurgical method from 8 unperturbed horses every 20 or 30 s for approximately 1 h. In all but 1 horse, sampling occurred during the broad circadian maximum in plasma cor...

journal_title：Neuroendocrinology

authors： Alexander SL,Irvine CH,Donald RA

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Synaptic plasticity is the neuronal capacity to modify the function and structure of dendritic spines (DS) in response to neuromodulators. Sex steroids, particularly 17β-estradiol (E2) and progesterone (P4), are key regulators in the control of DS formation through multiprotein complexes including WAVE1 prot...

journal_title：Neuroendocrinology

authors： Uzair ID,Flamini MI,Sanchez AM

更新日期：2020-01-01 00:00:00

abstract：:This study was carried out to clarify the central effects of neuropeptide Y (NPY) on gonadotropin and prolactin (PRL) release in the male rat and to evaluate the hypothesis that it may play a role in negative feedback regulation of gonadotropin secretion in the male. NPY (4 micrograms in 2 microliters 0.9% NaCl) or an...

journal_title：Neuroendocrinology

authors： Reznikov AG,McCann SM

更新日期：1993-06-01 00:00:00

abstract：:Vasoactive intestinal peptide (VIP), a prolactin (PRL)-releasing factor, has been shown to be synthesized within the anterior pituitary. To test the hypothesis that estrogens increase PRL secretion, at least in part, by stimulating VIP secretion, the concentrations of VIP, peptide histidine isoleucine (PHI) and prepro...

journal_title：Neuroendocrinology

authors： Lam KS,Srivastava G,Lechan RM,Lee T,Reichlin S

更新日期：1990-11-01 00:00:00

abstract：:Amygdalotomized, sham-operated and intact wild-derived house mice of both sexes were group-caged (8-10) or singly caged for 3 weeks. The weights of ovaries (p is less than 0.05) and uteri (p is less than 0.01) were less in intact and sham-operated grouped females compared to singly caged intact and amygdalotomized fem...

journal_title：Neuroendocrinology

authors： Pasley JN,Powell EW,Cernosek RM,Cernosek SF

更新日期：1978-01-01 00:00:00