Subfornical organ lesions reduce the pressor effect of systemic angiotensin II.

abstract：:A patch-clamp study was conducted on cultured frog pituitary melanotrophs, in order to investigate the effects of adrenaline on the electrical activity of these cells. In the whole-cell configuration, adrenaline (1 microM) caused hyperpolarization that was accompanied by a fall in membrane input resistance and a block...

journal_title：Neuroendocrinology

authors： Valentijn JA,Vaudry H,Cazin L

更新日期：1994-01-01 00:00:00

abstract：:The facilitation of sexual receptivity by oxytocin (OT) in female rats is related to the regulation of oxytocin receptors (OTR) by ovarian steroids in the ventromedial nuclei (VMN) of the hypothalamus. In a previous study, we have shown that estradiol benzoate (EB) causes a twofold increase in OTR binding in the VMN. ...

journal_title：Neuroendocrinology

authors： Coirini H,Johnson AE,Schumacher M,McEwen BS

更新日期：1992-03-01 00:00:00

abstract：:To determine whether the inhibitory effect of clonidine (CLON) on renin secretion is due in part to a direct action on the kidneys or due entirely to an action on the brain, the drug was administered intravenously in a dose of 30 microgram/kg to dogs in which the spinal cord had been transected in the cervical region....

journal_title：Neuroendocrinology

authors： Ganong WF,Wise BL,Reid IA,Holland J,Kaplan S,Shackelford R,Boryczka AT

更新日期：1978-01-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：:Studies were undertaken to investigate the nature of receptors involved in the prolactin-releasing action of histamine in male rats. The increase of plasma prolactin levels induced by third-ventricle injection of histamine was blocked by intraventricular injection of ranitidine, an H2-antagonist, but not by systemic a...

journal_title：Neuroendocrinology

authors： Donoso AO,Zárate MB,Seltzer A

更新日期：1983-06-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) stimulates GH secretion in man and the hormonal response is specific. The attenuation of GH response to bolus GHRH after prior exposure of GHRH of up to 24 h was not demonstrated in normal or GH-deficient subjects after more prolonged exposure. This suggests that the partial los...

journal_title：Neuroendocrinology

authors： Low LC

更新日期：1991-01-01 00:00:00

abstract：:Our laboratory has previously described the widespread distribution of an immunoreactive and bioactive rat growth hormone (rGH)-like protein in rat brain. It has also been demonstrated that regulation of pituitary rGH secretion is at least partly mediated by a short-loop negative feedback system. In such a system, inc...

journal_title：Neuroendocrinology

authors： Hojvat S,Emanuele NV,Kirsteins L,Lawrence AM

更新日期：1986-01-01 00:00:00

abstract：:The purpose of this study was to determine the effect of rendering newborn male Sprague-Dawley rats hypothyroid with 131I on development of the hypothalamic-pituitary axis. Hormonal responses to thyrotropin-releasing hormone (TRH), haloperidol (H), and luteinizing hormone-releasing hormone (LHRH) were determined at 9,...

journal_title：Neuroendocrinology

authors： Sowers JR,Resch G,Walker S,Sollars E

更新日期：1980-05-01 00:00:00

abstract：:In the present study we demonstrated that TLQP-21, a biologically active peptide derived from the processing of the larger pro-VGF granin, plays a role in mammotrophic cell differentiation. We used an established in vitro model, the GH3 cell line, which upon treatment with epidermal growth factor develops a mammotroph...

journal_title：Neuroendocrinology

authors： Petrocchi Passeri P,Biondini L,Mongiardi MP,Mordini N,Quaresima S,Frank C,Baratta M,Bartolomucci A,Levi A,Severini C,Possenti R

更新日期：2013-01-01 00:00:00

abstract：:The pituitary-adrenal axis is known to be stimulated during the acute-phase response. As cytokines play a central role in mediating the constellation of host response occurring during the acute-phase response it was of interest to assess the ability of cytokines to stimulate ACTH secretion from normal pituitary cells ...

journal_title：Neuroendocrinology

authors： Kehrer P,Turnill D,Dayer JM,Muller AF,Gaillard RC

更新日期：1988-08-01 00:00:00

abstract：:Galanin-like peptide (GALP) is a 60-amino-acid peptide with structural similarities to galanin and a high affinity for galanin receptors. GALP is expressed by a discrete population of neurons in the arcuate nucleus (ARC) and median eminence of the hypothalamus of several species, including the rat. GALP neurons expres...

journal_title：Neuroendocrinology

authors： Shen J,Gundlach AL

更新日期：2004-01-01 00:00:00

abstract：:Both the pituitary-adrenal axis and the pituitary-gonadal axis are under the tonic inhibitory control of endogenous opioid peptides in man. However, the precise opioid receptor involved in the modulation of these hormones remains unknown. The effect of a dose of intravenous naloxone on serum levels of luteinising horm...

journal_title：Neuroendocrinology

authors： Grossman A,Moult PJ,Cunnah D,Besser M

更新日期：1986-01-01 00:00:00

abstract：:The obese gene (OB) product, leptin, has been shown to exert control on metabolic processes such as food intake and body weight homeostasis, possibly through a neuropeptide Y (NPY) neurotransmission. More recently, leptin has been shown to control several neuroendocrine axes, modulating pituitary hormone secretions in...

journal_title：Neuroendocrinology

authors： Vuagnat BA,Pierroz DD,Lalaoui M,Englaro P,Pralong FP,Blum WF,Aubert ML

更新日期：1998-05-01 00:00:00

abstract：:The present study was undertaken in order to better characterize the functional state of anterior pituitary gland in young and old rats by using prolactin secretion and incorporation of radioactive phosphate into phosphatidylinositol (PI) as markers. The in vitro incorporation of radiolabeled phosphate into anterior p...

journal_title：Neuroendocrinology

authors： Bonetti AC,Bellini F,Calderini G,Galbiati E,Toffano G

更新日期：1987-02-01 00:00:00

abstract：:In the Siberian hamster the pituitary content of bioassayable MSH has been shown to be seasonally variable, being greater during the long days of spring and summer than during the short days of autumn and winter. Similar changes in the pituitary content of both bioassayable MSH and immunoreactive alpha MSH can be indu...

journal_title：Neuroendocrinology

authors： Logan A,Weatherhead B

更新日期：1980-05-01 00:00:00

abstract：:In the present study we utilized the 7315a PRL- and ACTH-secreting tumor to induce a hyperprolactinemic (HP) state sufficient to profoundly suppress the postcastration LH rise in female rats. Tumor-induced prolactin levels which ranged 2,000-3,000 ng/ml substantially reduced the LH rise in both ovariectomized (OVX) an...

journal_title：Neuroendocrinology

authors： Shu C,Selmanoff M

更新日期：1991-09-01 00:00:00

abstract：:Studies were undertaken to characterize the secretion of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) into the hypophysial-portal circulation of the conscious sheep. In addition, we examined the temporal relationship between the secretion of these two hypothalamic peptides and the secretion of t...

journal_title：Neuroendocrinology

authors： Engler D,Pham T,Fullerton MJ,Ooi G,Funder JW,Clarke IJ

更新日期：1989-04-01 00:00:00

abstract：:A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...

journal_title：Neuroendocrinology

authors： Mick G

更新日期：1995-03-01 00:00:00

abstract：:The possible implication of the amygdaloid central nucleus (ACE) of the rat in the control of ACTH secretion in response to immobilization stress was assessed. The ACTH secretion, in response to stress and/or bilateral lesions of the ACE, was correlated with the serotoninergic activity in specific hypothalamic and amy...

journal_title：Neuroendocrinology

authors： Beaulieu S,Di Paolo T,Barden N

更新日期：1986-01-01 00:00:00

abstract：:Unlike rats, but similar to primates, guinea pigs exhibit prolonged function of the corpus luteum and elevated progesterone secretion after ovulation. The gonadotropins, estrogen (E) and progesterone (P) have been examined throughout the guinea pig estrous cycle. However, neither prolactin secretion nor its regulation...

journal_title：Neuroendocrinology

authors： Bethea CL,Hess DL,Widmann AA,Henningfeld JM

更新日期：1995-06-01 00:00:00

abstract：UNLABELLED:Opioid peptides are present in both the posterior pituitary (PP) and stalk-median eminence (SME). Their effects on the dopaminergic neurons in the SME are well documented, but little is known concerning their role in the regulation of dopamine (DA) release from the PP. The objectives of this study were (1) t...

journal_title：Neuroendocrinology

authors： Garris PA,Ben-Jonathan N

更新日期：1990-10-01 00:00:00

abstract：:In the primate, arginine vasopressin (AVP) is known to activate the hypothalamo-pituitary-adrenal axis and to inhibit LH secretion. In the present study, we investigate the role of the endogenous opioid peptides and corticotropin-releasing hormone (CRH) in these processes. Adult ovariectomized rhesus monkeys bearing a...

journal_title：Neuroendocrinology

authors： Xiao E,Xia-Zhang L,Thornell D,Shalts E,Ferin M

更新日期：1996-09-01 00:00:00

abstract：:Immunoneutralization of endogenous gonadal steroids has recently been shown to modify pineal beta-adrenoceptor function in intact Merino ewes. In the current study, interactions between gonadal steroids and these receptors have been further investigated. beta-Adrenoceptor density and binding affinity both showed time-...

journal_title：Neuroendocrinology

authors： Foldes A,Maxwell CA,Scaramuzzi RJ,Donnelly JB,Hoskinson RM,Rintoul AJ

更新日期：1985-12-01 00:00:00

abstract：:There is extensive evidence that serotonin (5-HT) is implicated in the neuroendocrine control regulating the secretion of several anterior pituitary hormones. It has also been reported that the posterior pituitary is necessary for prolactin (PRL) response to 5-HT as well as to suckling, in which 5-HT implication has b...

journal_title：Neuroendocrinology

authors： Balsa JA,Sánchez-Franco F,Pazos F,Lara JI,Lorenzo MJ,Maldonado G,Cacicedo L

更新日期：1998-11-01 00:00:00

abstract：:The influence of catecholamines (CA) on hypothalamic somatostatin (HPT-SRIF) was investigated in rats by using several drugs which interfere with brain CA metabolism. Depletion of brain CA stores by alpha-methyl-rho-tyrosine (AMT) increased HPT-SRIF, while augmented brain CA levels following L-dopa administration decr...

journal_title：Neuroendocrinology

authors： Torres I,Guaza C,Fernandez-Durango R,Borrell J,Charro AL

更新日期：1982-01-01 00:00:00

abstract：:To assess whether gonadotropin-releasing hormone (GnRH) release from the hypothalamus might be altered by hyperprolactinemia in the male rat, we measured in chronically hyperprolactinemic rats the pituitary GnRH receptor content and described the pattern of luteinizing hormone (LH) release during the postcastration ri...

journal_title：Neuroendocrinology

authors： Fox SR,Hoefer MT,Bartke A,Smith MS

更新日期：1987-10-01 00:00:00

abstract：:Peptidyl-glycine alpha-amidation activity has been detected in human cerebrospinal fluid (CSF) and in several regions of the central nervous system. Activity was monitored by measuring conversion of mono-125I-D-Tyr-Val-Gly into mono-125I-D-Tyr-Val-NH2. The alpha-amidation activity in CSF is dependent on molecular oxyg...

journal_title：Neuroendocrinology

authors： Wand GS,Ney RL,Mains RE,Eipper BA

更新日期：1985-12-01 00:00:00

abstract：:The effect of the antidiarrheal drug loperamide, a mu-opiate agonist, on ACTH secretion and biosynthesis, cAMP generation and phosphoinositide turnover was studied in rat anterior pituitary cell cultures. The cAMP-dependent protein kinase A pathway was stimulated with both corticotropin-releasing hormone (CRH; 2-5 nM)...

journal_title：Neuroendocrinology

authors： Auernhammer CJ,Renner U,Müller OA,Stalla J,Stalla GK

更新日期：1993-06-01 00:00:00

abstract：:The following fragments of LHRH were administered intraventricularly and tested for their ability to enhance sexual receptivity in ovariectomized, estrogen-primed female rats: LHRH1-6 NH2, Ac-LHRH5-10, des-Tyr5-LHRH and des-Gly10-LHRH. LHRH1-6 NH2 had no effect on sexual behavior compared to saline-infused controls. A...

journal_title：Neuroendocrinology

authors： Dudley CA,Vale W,Rivier J,Moss RL

更新日期：1983-06-01 00:00:00

abstract：:The ability of neuropeptides to act as precursors for smaller, biologically active fragments is discussed in terms of their biotransformation. This process may involve cleavage of the parent peptide by peptidase enzymes to produce shorter polypeptides with defined biological activity, though other enzymic processes su...

journal_title：Neuroendocrinology

authors： Griffths EC,McDermott JR

更新日期：1984-12-01 00:00:00