Effects of tumor-induced hyperprolactinemia on LH secretion following stimulation of the medial preoptic area, pituitary responsiveness and the estrogen-induced LH surge.

abstract：:We have previously reported that luteinizing hormone releasing hormone (LH-RH) levels in the medial basal hypothalamus (MBH) of adult male rats castrated for 2 weeks can be raised by testosterone (T) or estradiol (E2) treatment for 3-4 days. The present study was undertaken to determine the time after castration when ...

journal_title：Neuroendocrinology

authors： Kalra PS

更新日期：1985-09-01 00:00:00

abstract：:The effect of sonicated suspensions of phosphatidylserine (PS), an acidic phospholipid, was investigated on prolactin secretion utilizing in vivo and in vitro approaches. Acute and chronic administration of PS reduced plasma prolactin levels during different phases of circadian rhythms. The phospholipid was able to in...

journal_title：Neuroendocrinology

authors： Canonico PL,Annunziato L,Toffano G,Bernardini R,Stanzani S,Foti M,Clementi G,Drago F,Scapagnini U

更新日期：1981-12-01 00:00:00

abstract：:We have examined the effect of electrical stimulation in the subfornical organ (SFO) on the activity of neurons in the medial septum and diagonal band of Broca (MS-DBB) which project to the median eminence in the rat. Previous studies have suggested that septal neurons with such projections are luteinizing hormone rel...

journal_title：Neuroendocrinology

authors： Donevan SD,Ferguson AV

更新日期：1988-07-01 00:00:00

abstract：:We have found thyroxine 5'-deiodinase in rat posterior pituitary. The isozyme pattern was different in intermediate and neural lobes. The former contained only type I enzyme. In the neural lobe, in euthyroidism only type I was found while in hypothyroidism type II was a prominent form. Since type II 5'-deiodinase has ...

journal_title：Neuroendocrinology

authors： Tanaka K,Murakami M,Greer MA

更新日期：1987-12-01 00:00:00

abstract：:Studies were performed to determine the role of thyroid hormone in the suppression of thyrotropin (TSH) by opiates. Serum samples were collected by decapitation 1, 3, 6, 12, 24, or 48 h after rats were implanted with 1 sustained-release morphine (75 mg) or placebo pellet. Morphine decreased TSH by 44% at 1 h and by 83...

journal_title：Neuroendocrinology

authors： Berglund LA,Millard WJ,Gabriel SM,Simpkins JW

更新日期：1990-09-01 00:00:00

abstract：:Phase relation between plasma corticosterone and locomotor activity rhythms was analyzed in individual rats with selective lesions of suprachiasmatic nuclei (SCN). SCN in Wistar male rats were selectively coagulated electrically and the extent of SCN destruction was examined histologically. Spontaneous locomotor activ...

journal_title：Neuroendocrinology

authors： Watanabe K,Hiroshige T

更新日期：1981-07-01 00:00:00

abstract：INTRODUCTION:Acromegaly is commonly complicated by arthropathy and skeletal fragility with high risk of vertebral fractures (VFs). OBJECTIVE:This study aimed to assess whether VFs may be associated with sagittal spine deformities, arthropathy, impaired quality of life (QoL), pain and disability. METHODS:Thirty-eight ...

journal_title：Neuroendocrinology

authors： Cellini M,Biamonte E,Mazza M,Trenti N,Ragucci P,Milani D,Ferrante E,Rossini Z,Lavezzi E,Sala E,Mantovani G,Arosio M,Fornari M,Balzarini L,Lania AG,Mazziotti G

更新日期：2020-09-25 00:00:00

abstract：:Studies were undertaken to determine the effects of chronic stimulation of opiate receptors on the negative feedback effects of testosterone (T) on luteinizing hormone (LH) secretion in the male rat. In an initial study, castrated male rats received replacement levels of T (2 ng/ml) or chronic morphine (M) treatment f...

journal_title：Neuroendocrinology

authors： Gabriel SM,Simpkins JW,Kalra SP,Kalra PS

更新日期：1985-01-01 00:00:00

abstract：:Hypophysectomized male rats with adenohypophyses grafted under the kidney capsule (HG rat) for 3 weeks with or without estradiol implantation, were used to examine prolactin (PRL) secretion independent of hypothalamic influence. Changes in the circulating PRL concentration were monitored by taking blood samples every ...

journal_title：Neuroendocrinology

authors： Shin SH,Reifel CW

更新日期：1981-03-01 00:00:00

abstract：:The presence of enzymatic activity (tyrosine hydroxylase, dopa-decarboxylase, dopamine-beta-hydroxylase, monoamine oxydase and catechol-O-methyl transferase), as well as dopamine (DA) content and DA synthesis from tyrosine and dopa, were investigated in intact rats partes distales and in grafts (both estrogenized and ...

journal_title：Neuroendocrinology

authors： Iturriza FC,Rubio MC,Gómez Dumm CL,Zieher LM

更新日期：1983-11-01 00:00:00

abstract：:The A1 and A2 brainstem noradrenergic cell groups project to the hypothalamic paraventricular nucleus (PVN), which is involved in integrating the stress response. Bi-directional communication between the brain and immune system is well established, with both neuroendocrine and immune responses being activated by lipop...

journal_title：Neuroendocrinology

authors： Condé GL,Renshaw D,Zubelewicz B,Lightman SL,Harbuz MS

更新日期：1999-09-01 00:00:00

abstract：:The push-pull perfusion technique, in conjunction with specific radioimmunoassays, was used to monitor the release of both arginine vasopressin (AVP) and oxytocin (OXT) within distinct limbic brain areas of conscious female rats. In pregnant rats near term, the release of AVP was greater than that of virgin rats in bo...

journal_title：Neuroendocrinology

authors： Landgraf R,Neumann I,Pittman QJ

更新日期：1991-10-01 00:00:00

abstract：:Previous reports have shown that dopamine (DA) in the zona incerta (ZI) has a stimulatory effect on gonadotrophin release. We have now investigated the possibility that steroids exert their feedback effects on the release of luteinizing hormone (LH) via catecholamine systems in the ZI. Since the same steroid regimes a...

journal_title：Neuroendocrinology

authors： Wilson CA,James MD,Grierson JP,Hole DR

更新日期：1991-02-01 00:00:00

abstract：:The regulation of prolactin secretion by tuberoinfundibular dopamine (DA) neurons appears to be altered in the aged rat: the concentration of prolactin in the serum increases and the activity of the tuberoinfundibular DA neurons decreases. In the young female rat a brief period of stress reduces the tuberoinfundibular...

journal_title：Neuroendocrinology

authors： Demarest KT,Moore KE,Riegle GD

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND/AIMS:Tryptophan is the precursor of serotonin and niacin (vitamin B3). The latter is critical for normal cellular metabolism. Tryptophan and niacin can be deficient in patients with serotonin-producing neuroendocrine tumors (NETs). Niacin deficiency may lead to severe symptoms including pellagra. In patients...

journal_title：Neuroendocrinology

authors： Bouma G,van Faassen M,Kats-Ugurlu G,de Vries EG,Kema IP,Walenkamp AM

更新日期：2016-01-01 00:00:00

abstract：:Previous studies have shown that prepubertal olfactory bulbectomy will prevent the testicular regression associated with short photoperiod in golden hamsters. The gonadal regression which normally occurs in hamsters on short photoperiod is known to be due in part to an increased responsiveness of the reproductive neur...

journal_title：Neuroendocrinology

authors： Pieper DR,Unthank PD,Shuttie DA,Lobocki CA,Swann JM,Newman S,Subramanian MG

更新日期：1987-10-01 00:00:00

abstract：:Acute electrolytic stimulation of the median raphe (MR) nucleus (MR Stim) between 13:00 and 16:00 h on proestrus blocked ovulation in 10 of the 21 rats tested, whereas all sham-treated (MR Sham, no current) animals ovulated normally (n = 12). MR Stim at 16:00 h on proestrus in individual cannulated rats 'turned off' t...

journal_title：Neuroendocrinology

authors： Barofsky AL

更新日期：1979-01-01 00:00:00

abstract：:Observations in experimental allergic encephalomyelitis (EAE), a model for multiple sclerosis (MS), have indicated that a low activity of the hypothalamo-pituitary-adrenal (HPA) system is accompanied by a high susceptibility for EAE in rat strains and that elevated corticosteroid levels are necessary for spontaneous r...

journal_title：Neuroendocrinology

authors： Purba JS,Raadsheer FC,Hofman MA,Ravid R,Polman CH,Kamphorst W,Swaab DF

更新日期：1995-07-01 00:00:00

abstract：:To elucidate the mechanisms of the impaired pituitary response to growth hormone-releasing hormone (GHRH) in aged animals on a cellular basis, a reverse hemolytic plaque assay was performed on dispersed pituitary cells from young (8-month-old) and old (26-month-old) male F344 rats. The proportion of growth hormone (GH...

journal_title：Neuroendocrinology

authors： Shimokawa I,Higami Y,Okimoto T,Ikeda T

更新日期：1994-12-01 00:00:00

abstract：:Leptin, the product of the obese gene, is a protein that is secreted primarily from adipocytes. Leptin can influence the function of the pituitary gland through its action on the hypothalamus, but it can also directly act at the level of the pituitary gland. The ability of leptin to induce an increase in intracellular...

journal_title：Neuroendocrinology

authors： Glavaski-Joksimovic A,Rowe EW,Jeftinija K,Scanes CG,Anderson LL,Jeftinija S

更新日期：2004-01-01 00:00:00

abstract：:Substance P (SP) is known to act on pituitary hormone release either at the hypothalamic level or directly at the pituitary level. In order to investigate whether SP is present in the pituitary gland and to localize the peptide at the cellular and subcellular levels, the immunocytological method was used. Rat pituitar...

journal_title：Neuroendocrinology

authors： Morel G,Chayvialle JA,Kerdelhue B,Dubois PM

更新日期：1982-01-01 00:00:00

abstract：:Ciliary neurotropic factor (CNTF) is a neuroregulatory cytokine belonging to the interleukin-6 type cytokine superfamily. Although a few studies have reported a facilitatory action of CNTF on the reproductive axis in rodents, information along this line is still very limited. In this study, we examined a possible role...

journal_title：Neuroendocrinology

authors： Watanobe H,Habu S

更新日期：2001-11-01 00:00:00

abstract：:The effects of acute and chronic administration of a combination of lynestrenol-mestrenol, a widely employed contraceptive medication, on the dopaminergic system of the rat forebrain and striatum were investigated to better understand the biochemical basis of the neurological side-effects of steroid contraceptive drug...

journal_title：Neuroendocrinology

authors： Algeri S,Ponzio F,Dolfini E,Jori A

更新日期：1976-01-01 00:00:00

abstract：:A prolactin (PRL) surge occurs in the female rat during proestrus in response to elevated estradiol levels. The elevated release of ovarian steroids on the day of proestrus is also associated with sexual receptivity. Mating triggers twice-daily PRL surges that supplant the proestrous PRL surge and are responsible for ...

journal_title：Neuroendocrinology

authors： Yang S,Lee Y,Voogt JL

更新日期：1999-04-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) receptors were characterized and their function investigated in mouse pituitary neurointermediate lobe explants. We show that mouse neurointermediate lobes can be maintained for up to 1 month in defined medium. After 8 days in culture, these explants are devoi...

journal_title：Neuroendocrinology

authors： René F,Monnier D,Gaiddon C,Félix JM,Loeffler JP

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...

journal_title：Neuroendocrinology

authors： Poletini MO,Kennett JE,McKee DT,Freeman ME

更新日期：2010-01-01 00:00:00

abstract：:Interruption of hypothalamic growth hormone-releasing hormone (GHRH) secretion by administration of antiserum against GHRH (GHRH-ab) decreases growth hormone (GH) secretion and inhibits growth in rats. The present study was undertaken to investigate whether there is a period of accelerated or catch-up growth following...

journal_title：Neuroendocrinology

authors： Wehrenberg WB,Voltz DM,Cella SG,Müller EE,Gaillard RC

更新日期：1992-10-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：:We studied the effects of selected leukotrienes and hydroxyeicosatetraenoic acids (HETEs) on prolactin release from primary cultures of female rats anterior pituitary cells. Leukotrienes B4, C4, and D4 had no effect on basal prolactin release; however, they did enhance prolactin release that was stimulated by 1 or 5 n...

journal_title：Neuroendocrinology

authors： Judd AM,Spangelo BL,Ehreth JT,MacLeod RM

更新日期：1988-10-01 00:00:00

abstract：CONTEXT:Early pubertal luteinizing hormone (LH), and by inference gonadotropin-releasing hormone (GnRH), pulse secretion is marked by high nocturnal but low daytime frequency; however, the underlying mechanisms remain unclear. Plasma concentrations of progesterone, the major regulator of GnRH frequency in women, increa...

journal_title：Neuroendocrinology

authors： Collins JS,Marshall JC,McCartney CR

更新日期：2012-01-01 00:00:00