Hyperprolactinemia induced by pituitary isografts suppresses the priming effect of LH-releasing hormone in normal and hypogonadal mice.

abstract：:A significant increase of cell multiplication in inoculated ascitic and solid tumors was demonstrated in both DBA/2 and C57BL/6 mice as well as in Wistar rats after radiofrequency lesions in the median hypothalamus (ventromedial and dorsomedial nuclei; part of arcuate nucleus). The following tests were performed: mito...

journal_title：Neuroendocrinology

authors： Bindoni M,Belluardo N,Marchese AE,Cardile V,Mudò G,Cella S,Laguidara A,Denatale G

更新日期：1986-01-01 00:00:00

abstract：:Bromocriptine or other dopamine agonists are usually effective for the treatment of prolactin-secreting adenomas. Five to 18% of prolactinomas, however, do not respond to such therapy. We have shown previously that such resistance to bromocriptine correlates with reduced binding to the D2 receptor subtype of dopamine,...

journal_title：Neuroendocrinology

authors： Caccavelli L,Feron F,Morange I,Rouer E,Benarous R,Dewailly D,Jaquet P,Kordon C,Enjalbert A

更新日期：1994-09-01 00:00:00

abstract：:Both the pituitary-adrenal axis and the pituitary-gonadal axis are under the tonic inhibitory control of endogenous opioid peptides in man. However, the precise opioid receptor involved in the modulation of these hormones remains unknown. The effect of a dose of intravenous naloxone on serum levels of luteinising horm...

journal_title：Neuroendocrinology

authors： Grossman A,Moult PJ,Cunnah D,Besser M

更新日期：1986-01-01 00:00:00

abstract：:Immunoreactive thyroid-stimulating hormone (IR-TSH) has been detected in the hypothalamus and is released in vitro by a calcium-dependent mechanism when the tissue is depolarized. Recently, immunocytochemical studies have revealed that IR-TSH is present in thyrotropes in the pars tuberalis. Therefore, because these th...

journal_title：Neuroendocrinology

authors： De Vito WJ,Connors JM,Hedge GA

更新日期：1985-07-01 00:00:00

abstract：:Neuropeptide W (NPW) is a ligand of the recently deorphaned receptor GPR7. Intracerebroventricular injection of this peptide results in reduced serum growth hormone concentration. Using whole-cell patch clamp recordings from somatostatin (SS) neurons in the hypothalamic arcuate nucleus, identified post-hoc using singl...

journal_title：Neuroendocrinology

authors： Price CJ,Samson WK,Ferguson AV

更新日期：2008-01-01 00:00:00

abstract：:The sleep-wakefulness pattern and brain protein levels were determined in rats for 3 h following these conditions: administration of an inhibitor of protein synthesis (anisomycin), administration of several doses of rat growth hormone (GH) or thyrotropin, and administration of a combination of anisomycin + GH or thyro...

journal_title：Neuroendocrinology

authors： Drucker-Colín RR,Spanis CW,Hunyadi J,Sassin JF,McGaugh JL

更新日期：1975-01-01 00:00:00

abstract：:Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...

journal_title：Neuroendocrinology

authors： Simar MR,Saphier D,Goeders NE

更新日期：1996-01-01 00:00:00

abstract：:The possible role of prostaglandins (PGs) in the hypothalamic control of ovulation has been investigated by studying the effects of indomethacin (ID) and PGs on the release of luteinizing hormone-releasing hormone (LHRH) from hypothalamic synaptosomes. Female rats were chronically pretreated with ID on diestrus 2 (D2)...

journal_title：Neuroendocrinology

authors： Linton EA,Bennett GW,Whitehead SA

更新日期：1979-01-01 00:00:00

abstract：:Brain corticosteroid receptors, the type 1 mineralocorticoid receptor (MR) and the type 2 glucocorticoid receptor (GR), are involved in the regulation of neuroendocrine and behavioral responses during ongoing and stressful conditions. To further investigate the role of MR in these responses, we treated male Wistar rat...

journal_title：Neuroendocrinology

authors： Reul JM,Probst JC,Skutella T,Hirschmann M,Stec IS,Montkowski A,Landgraf R,Holsboer F

更新日期：1997-03-01 00:00:00

abstract：:It has been recently demonstrated that luteinizing hormone-releasing hormone (LHRH) can inhibit LHRH release by the hypothalamus, suggesting an ultrashort feedback of LHRH on LHRH neurons. In order to test this hypothesis, immunocytochemical localization of LHRH was conducted in the preoptic area of the rat brain. Con...

journal_title：Neuroendocrinology

authors： Pelletier G

更新日期：1987-11-01 00:00:00

abstract：:During adult-onset peripheral hypothyroidism, the brain maintains normal levels of thyroid hormone for some time through a mechanism of 'central homeostasis'. Although onset, duration, and termination of such a homeostatic phenomenon have been recently evaluated in rat models, the mechanism behind remains unknown. Dur...

journal_title：Neuroendocrinology

authors： Kundu S,Roy S,De J,Biswas A,Pramanik M,Ray AK

更新日期：2007-01-01 00:00:00

abstract：:We have studied some of the neuroendocrine and social correlates of dexamethasone resistance in a nonhuman primate population. Subjects were 51 male Macaca fascicularis monkeys with known behavioral histories and who had been given dexamethasone (DEX) suppression tests a week prior to killing. We compared the subset o...

journal_title：Neuroendocrinology

authors： Brooke SM,de Haas-Johnson AM,Kaplan JR,Manuck SB,Sapolsky RM

更新日期：1994-08-01 00:00:00

abstract：:Met-enkephalin concentrations in the anterior pituitary gland were shown to decline dramatically within the first 24 h after reserpine treatment, with effects apparent as early as 6 h. This was followed by subsequent repletion and late augmentation of Met-enkephalin levels 3 weeks following reserpine. Treatment with t...

journal_title：Neuroendocrinology

authors： George SR,Kertesz M

更新日期：1988-02-01 00:00:00

abstract：:The possible implication of the amygdaloid central nucleus (ACE) of the rat in the control of ACTH secretion in response to immobilization stress was assessed. The ACTH secretion, in response to stress and/or bilateral lesions of the ACE, was correlated with the serotoninergic activity in specific hypothalamic and amy...

journal_title：Neuroendocrinology

authors： Beaulieu S,Di Paolo T,Barden N

更新日期：1986-01-01 00:00:00

abstract：:To study the eyes' role in maintaining the circadian rhythm in pituitary-adrenal function, 24-h patterns of corticosterone levels were compared in intact and blinded adult female rats. Rats were blinded by optic enucleation at approximately 80 days of age. Nonstress plasma corticosterone levels were determined fluorom...

journal_title：Neuroendocrinology

authors： Wilson MM,Rice RW,Critchlow V

更新日期：1976-01-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is involved in the regulation and maintenance of gametogenesis. It exists in multiple molecular forms with different oligosaccharide structures which in turn are influenced by the hormonal milieu. Previous studies from our laboratory demonstrated that antiandrogen administration to i...

journal_title：Neuroendocrinology

authors： Rulli SB,Creus S,Pellizzari E,Cigorraga SB,Calandra RS,Campo S

更新日期：1999-10-01 00:00:00

abstract：:To assess the neuroendocrine correlates of menstrual status migrainosus (MSM) and menstrual migraine (MM), we evaluated the prolactin (PRL) and cortisol responses to the direct central serotoninergic (5-HT) agonist meta-chlorophenylpiperazine (m-CPP) administered orally (0.5 mg/kg) during the follicular (FP: +6, +8) a...

journal_title：Neuroendocrinology

authors： Nappi RE,Sances G,Brundu B,Ghiotto N,Detaddei S,Biancardi C,Polatti F,Nappi G

更新日期：2003-07-01 00:00:00

abstract：:The effects of GABAa receptor activation on the secretion of alpha-melanocyte-stimulating hormone (alpha-MSH) from the superfused pars intermedia of the amphibian Xenopus laevis were examined. The GABAa receptor agonist isoguvacine inhibited secretion of alpha-MSH from the pars intermedia, an action completely antagon...

journal_title：Neuroendocrinology

authors： Jenks BG,de Koning HP,Valentijn K,Roubos EW

更新日期：1993-07-01 00:00:00

abstract：:A consistent group of gonadotropin-releasing hormone (GnRH) cell bodies occurs in the ventral hypothalamic tract at the infundibular lip (IL), just below the arcuate nucleus (ARC), at the site of the so-called GnRH 'pulse generator'. Immunocytochemical studies were performed to examine contacts between these GnRH neur...

journal_title：Neuroendocrinology

authors： Thind KK,Goldsmith PC

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors (NETs) are rare and characterized by a heterogeneous clinical course and an unmet need for better prognostic markers. Plasma cell-free DNA (cfDNA) has prognostic value in other malignancies but is not previously investigated in NETs. We studied cfDNA levels in patients with mainly low g...

journal_title：Neuroendocrinology

authors： Oversoe SK,Sorensen BS,Tabaksblat EM,Gronbaek H,Kelsen J

更新日期：2021-01-18 00:00:00

abstract：:The electrical properties of GH3 cells, a transformed line from the rat pituitary, were studied with a current-clamp technique in the presence of triiodothyronine (T3) and reverse triiodothyronine (rT3) and compared with the known effects of T3. rT3 had an effect only in a concentration of 1 microM; action potentials ...

journal_title：Neuroendocrinology

authors： du Pont JS

更新日期：1991-08-01 00:00:00

abstract：:The effects of intracerebroventricularly (i.c.v.) injected interleukin-1 beta (IL-1 beta: 1, 2.5, 10, and 25 ng) were studied on plasma growth hormone (GH) and prolactin (PRL) concentrations in freely moving rats chronically implanted with i.c.v. cannulas and intracardial catheters. Significant changes in PRL secretio...

journal_title：Neuroendocrinology

authors： Payne LC,Obal F Jr,Opp MR,Krueger JM

更新日期：1992-07-01 00:00:00

abstract：:To assess whether gonadotropin-releasing hormone (GnRH) release from the hypothalamus might be altered by hyperprolactinemia in the male rat, we measured in chronically hyperprolactinemic rats the pituitary GnRH receptor content and described the pattern of luteinizing hormone (LH) release during the postcastration ri...

journal_title：Neuroendocrinology

authors： Fox SR,Hoefer MT,Bartke A,Smith MS

更新日期：1987-10-01 00:00:00

abstract：:In the present study the effect of methadone (M) on gonadotropin-releasing hormone in the rat hypothalamus was investigated. The specificity of the M effect was demonstrated by injecting M (100 ng) and the M antagonist, naloxone (5 ng), into the ventromedial hypothalamus. A significant drop in the blood testosterone l...

journal_title：Neuroendocrinology

authors： Singh HH,Purohit V,Ahluwalia BS

更新日期：1982-01-01 00:00:00

abstract：:Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1,...

journal_title：Neuroendocrinology

authors： Jia R,Sulentic P,Xu JM,Grossman AB

更新日期：2017-01-01 00:00:00

abstract：:The effect of in vivo corticosterone manipulation on binding sites for the excitatory neurotransmitter glutamate was determined using radioligand binding to rat brain cryostat sections and crude synaptic membranes. 3H-glutamate binding to regions of the dorsal hippocampal formation was significantly decreased in adren...

journal_title：Neuroendocrinology

authors： Halpain S,McEwen BS

更新日期：1988-09-01 00:00:00

abstract：:Infusion of 2 nmol atrial natriuretic factor (ANF) into the third cerebroventricle of conscious, orchidectomized male rats results in a significant inhibition of prolactin (PRL) secretion. This effect is prevented by prior treatment with the dopamine receptor antagonist, domperidone. Furthermore, domperidone reverses ...

journal_title：Neuroendocrinology

authors： Samson WK,Bianchi R,Mogg R

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Manipulating thyroid hormones has been shown to influence learning and memory. Although a large body of literature is available on the effects of thyroid hormone deficiency on learning and memory functions during developmental or adult-onset hypothyroidism, electrophysiological findings are limited. This lim...

journal_title：Neuroendocrinology

authors： Taşkın E,Artis AS,Bitiktas S,Dolu N,Liman N,Süer C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. AIM:To evaluate the clinicopathological features and therapeutic outcomes of CP diagnosed in the elderly. PATIENTS AND METHODS:A retrospective, multicenter, national study of C...

journal_title：Neuroendocrinology

authors： Iglesias P,Nocete I,Moure Rodríguez MD,Venegas-Moreno E,Ares J,Biagetti B,Rodríguez Berrocal V,Guerrero-Pérez F,Vicente A,Villar-Taibo R,Cordido F,Paja M,Glerean M,González Rivera N,Dios Fuentes E,Blanco C,Alvaréz-Escolá

更新日期：2020-10-09 00:00:00

abstract：:TRPM8 is a member of the melastatin-type transient receptor potential ion channel family. Activation by cold or by agonists (menthol, icilin) induces a transient rise in intracellular free calcium concentration ([Ca(2+)](i)). Our previous study demonstrated that Ca(2+)-permeable cation channels play a role in IGF-1-in...

journal_title：Neuroendocrinology

authors： Mergler S,Strowski MZ,Kaiser S,Plath T,Giesecke Y,Neumann M,Hosokawa H,Kobayashi S,Langrehr J,Neuhaus P,Plöckinger U,Wiedenmann B,Grötzinger C

更新日期：2007-01-01 00:00:00