Quantitative histochemical studies of the hypothalamus. Control point enzymes following androgen sterilization.

Abstract:

:Three control point enzymes of the Embden-Meyerhof pathway, hexokinase (HK), phosphofructokinase (PFK) and pyruvate kinase (PK) were measured by quantitative histochemical methods in individual hypothalamic nuclei of adult neonatally androgenized female rats. HK activity was significantly increased in anterior hypothalamic nuclei: medial preoptic, lateral preoptic, and suprachiasmatic. PK was significantly elevated in the lateral preoptic and suprachiasmatic nuclei of the anterior hypothalamus and also in the medial mamillary nucleus and median eminence. No significant changes occurred in PFK activity.

journal_name

Neuroendocrinology

journal_title

Neuroendocrinology

authors

Packman PM,Bragdon MJ,Boshans RL

doi

10.1159/000122715

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

261-9

issue

5-6

eissn

0028-3835

issn

1423-0194

journal_volume

24

pub_type

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